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Acute myocardial infarction

MedGen UID:
57611
•Concept ID:
C0155626
•
Disease or Syndrome
Synonyms: Acute Myocardial Infarction; acute myocardial infarction; acute myocardial infarction (disease); AMI - Acute myocardial infarction; myocardial infarction (disease), acute
SNOMED CT: AMI - Acute myocardial infarction (57054005); Acute myocardial infarction (57054005)
 
Monarch Initiative: MONDO:0004781

Definition

Necrosis of the myocardium, as a result of interruption of the blood supply to the area. It is characterized by a severe and rapid onset of symptoms that may include chest pain, often radiating to the left arm and left side of the neck, dyspnea, sweating, and palpitations. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • Acute myocardial infarction

Professional guidelines

PubMed

Cardiogenic Shock: Pathogenesis, Classification, and Management.
Sarma D, Jentzer JC
Crit Care Clin 2024 Jan;40(1):37-56. Epub 2023 Jul 6 doi: 10.1016/j.ccc.2023.05.001. PMID: 37973356
Fundamental Pathobiology of Coronary Atherosclerosis and Clinical Implications for Chronic Ischemic Heart Disease Management-The Plaque Hypothesis: A Narrative Review.
Stone PH, Libby P, Boden WE
JAMA Cardiol 2023 Feb 1;8(2):192-201. doi: 10.1001/jamacardio.2022.3926. PMID: 36515941Free PMC Article
Management of cardiogenic shock.
Thiele H, de Waha-Thiele S, Freund A, Zeymer U, Desch S, Fitzgerald S
EuroIntervention 2021 Aug 27;17(6):451-465. doi: 10.4244/EIJ-D-20-01296. PMID: 34413010Free PMC Article

Curated

UK NICE guideline NG185, Acute coronary syndromes, 2020

Recent clinical studies

Etiology

Assessment of Inflammatory Hematological Ratios (NLR, PLR, MLR, LMR and Monocyte/HDL-Cholesterol Ratio) in Acute Myocardial Infarction and Particularities in Young Patients.
Tudurachi BS, Anghel L, Tudurachi A, Sascău RA, Stătescu C
Int J Mol Sci 2023 Sep 21;24(18) doi: 10.3390/ijms241814378. PMID: 37762680Free PMC Article
Acute Myocardial Infarction: Etiologies and Mimickers in Young Patients.
Krittanawong C, Khawaja M, Tamis-Holland JE, Girotra S, Rao SV
J Am Heart Assoc 2023 Sep 19;12(18):e029971. doi: 10.1161/JAHA.123.029971. PMID: 37724944Free PMC Article
Acute Myocardial Infarction in Pregnancy.
Gédéon T, Akl E, D'Souza R, Altit G, Rowe H, Flannery A, Siriki P, Bhatia K, Thorne S, Malhamé I
Curr Probl Cardiol 2022 Nov;47(11):101327. Epub 2022 Jul 25 doi: 10.1016/j.cpcardiol.2022.101327. PMID: 35901856
Acute Myocardial Infarction after Laboratory-Confirmed Influenza Infection.
Kwong JC, Schwartz KL, Campitelli MA, Chung H, Crowcroft NS, Karnauchow T, Katz K, Ko DT, McGeer AJ, McNally D, Richardson DC, Rosella LC, Simor A, Smieja M, Zahariadis G, Gubbay JB
N Engl J Med 2018 Jan 25;378(4):345-353. doi: 10.1056/NEJMoa1702090. PMID: 29365305
Acute myocardial infarction.
Reed GW, Rossi JE, Cannon CP
Lancet 2017 Jan 14;389(10065):197-210. Epub 2016 Aug 5 doi: 10.1016/S0140-6736(16)30677-8. PMID: 27502078

Diagnosis

The Rise of T2.
Nagel E, Pappas L
JACC Cardiovasc Imaging 2024 Jun;17(6):622-624. Epub 2024 May 8 doi: 10.1016/j.jcmg.2024.03.013. PMID: 38727645
Acute Myocardial Infarction: Etiologies and Mimickers in Young Patients.
Krittanawong C, Khawaja M, Tamis-Holland JE, Girotra S, Rao SV
J Am Heart Assoc 2023 Sep 19;12(18):e029971. doi: 10.1161/JAHA.123.029971. PMID: 37724944Free PMC Article
Treatment strategies of acute myocardial infarction: updates on revascularization, pharmacological therapy, and beyond.
Saito Y, Oyama K, Tsujita K, Yasuda S, Kobayashi Y
J Cardiol 2023 Feb;81(2):168-178. Epub 2022 Jul 23 doi: 10.1016/j.jjcc.2022.07.003. PMID: 35882613
Acute Myocardial Infarction after Laboratory-Confirmed Influenza Infection.
Kwong JC, Schwartz KL, Campitelli MA, Chung H, Crowcroft NS, Karnauchow T, Katz K, Ko DT, McGeer AJ, McNally D, Richardson DC, Rosella LC, Simor A, Smieja M, Zahariadis G, Gubbay JB
N Engl J Med 2018 Jan 25;378(4):345-353. doi: 10.1056/NEJMoa1702090. PMID: 29365305
The acute myocardial infarction.
Pollard TJ
Prim Care 2000 Sep;27(3):631-49;vi. doi: 10.1016/s0095-4543(05)70167-6. PMID: 10918673

Therapy

Stem cells therapy in acute myocardial infarction: a new era?
Carbone RG, Monselise A, Bottino G, Negrini S, Puppo F
Clin Exp Med 2021 May;21(2):231-237. Epub 2021 Jan 23 doi: 10.1007/s10238-021-00682-3. PMID: 33484381Free PMC Article
Oxygen therapy for acute myocardial infarction.
Cabello JB, Burls A, Emparanza JI, Bayliss SE, Quinn T
Cochrane Database Syst Rev 2016 Dec 19;12(12):CD007160. doi: 10.1002/14651858.CD007160.pub4. PMID: 27991651Free PMC Article
A randomized trial of propranolol in patients with acute myocardial infarction. I. Mortality results.
JAMA 1982 Mar 26;247(12):1707-14. doi: 10.1001/jama.1982.03320370021023. PMID: 7038157
Timolol-induced reduction in mortality and reinfarction in patients surviving acute myocardial infarction.
Norwegian Multicenter Study Group
N Engl J Med 1981 Apr 2;304(14):801-7. doi: 10.1056/NEJM198104023041401. PMID: 7010157
Effect on mortality of metoprolol in acute myocardial infarction. A double-blind randomised trial.
Hjalmarson A, Elmfeldt D, Herlitz J, Holmberg S, Málek I, Nyberg G, Rydén L, Swedberg K, Vedin A, Waagstein F, Waldenström A, Waldenström J, Wedel H, Wilhelmsen L, Wilhelmsson C
Lancet 1981 Oct 17;2(8251):823-7. doi: 10.1016/s0140-6736(81)91101-6. PMID: 6116950

Prognosis

Acute Myocardial Infarction Following Hospitalization for Gastrointestinal Bleeding: Incidence, Predictors, Management, and Outcomes.
Rubinfeld GD, Berger JS, Smilowitz NR
Am J Med 2022 Aug;135(8):e263-e278. Epub 2022 Apr 22 doi: 10.1016/j.amjmed.2022.03.030. PMID: 35469734Free PMC Article
The landscape of cardiogenic shock: epidemiology and current definitions.
Palacios Ordonez C, Garan AR
Curr Opin Cardiol 2022 May 1;37(3):236-240. Epub 2022 Mar 11 doi: 10.1097/HCO.0000000000000957. PMID: 35275890
Early Readmissions After Acute Myocardial Infarction.
Kwok CS, Wong CW, Shufflebotham H, Brindley L, Fatima T, Shufflebotham A, Barker D, Pawala A, Heatlie G, Mamas MA
Am J Cardiol 2017 Sep 1;120(5):723-728. Epub 2017 Jun 15 doi: 10.1016/j.amjcard.2017.05.049. PMID: 28728745
Siena EVAR Score.
Setacci F, Sirignano P, Galzerano G, De Donato G, Ceriello D, Paroni G, Cappelli A, Setacci C
J Cardiovasc Surg (Torino) 2012 Apr;53(2):229-34. PMID: 22456646
Cardiogenic shock.
Hollenberg SM, Kavinsky CJ, Parrillo JE
Ann Intern Med 1999 Jul 6;131(1):47-59. doi: 10.7326/0003-4819-131-1-199907060-00010. PMID: 10391815

Clinical prediction guides

The Rise of T2.
Nagel E, Pappas L
JACC Cardiovasc Imaging 2024 Jun;17(6):622-624. Epub 2024 May 8 doi: 10.1016/j.jcmg.2024.03.013. PMID: 38727645
Accelerated -Rule-Out of acute Myocardial Infarction using prehospital copeptin and in-hospital troponin: The AROMI study.
Pedersen CK, Stengaard C, Bøtker MT, Søndergaard HM, Dodt KK, Terkelsen CJ
Eur Heart J 2023 Oct 12;44(38):3875-3888. doi: 10.1093/eurheartj/ehad447. PMID: 37477353Free PMC Article
Diagnostic and prognostic value of biomarkers in acute myocardial infarction.
Chen Y, Tao Y, Zhang L, Xu W, Zhou X
Postgrad Med J 2019 Apr;95(1122):210-216. Epub 2019 Apr 4 doi: 10.1136/postgradmedj-2019-136409. PMID: 30948439
Heartbeat: Rule-out of acute myocardial infarction - risky business.
Bradley SM, Otto CM
Heart 2016 Aug 15;102(16):1249-50. doi: 10.1136/heartjnl-2016-310271. PMID: 27471189
Internal validation of predictive models: efficiency of some procedures for logistic regression analysis.
Steyerberg EW, Harrell FE Jr, Borsboom GJ, Eijkemans MJ, Vergouwe Y, Habbema JD
J Clin Epidemiol 2001 Aug;54(8):774-81. doi: 10.1016/s0895-4356(01)00341-9. PMID: 11470385

Recent systematic reviews

Complete Percutaneous Coronary Revascularization in Acute Coronary Syndromes With Multivessel Coronary Disease: A Systematic Review.
Faro DC, Laudani C, Agnello FG, Ammirabile N, Finocchiaro S, Legnazzi M, Mauro MS, Mazzone PM, Occhipinti G, Rochira C, Scalia L, Spagnolo M, Greco A, Capodanno D
JACC Cardiovasc Interv 2023 Oct 9;16(19):2347-2364. doi: 10.1016/j.jcin.2023.07.043. PMID: 37821180
Extracorporeal life support during cardiac arrest and cardiogenic shock: a systematic review and meta-analysis.
Ouweneel DM, Schotborgh JV, Limpens J, Sjauw KD, Engström AE, Lagrand WK, Cherpanath TGV, Driessen AHG, de Mol BAJM, Henriques JPS
Intensive Care Med 2016 Dec;42(12):1922-1934. Epub 2016 Sep 19 doi: 10.1007/s00134-016-4536-8. PMID: 27647331Free PMC Article
Participation and adherence to cardiac rehabilitation programs. A systematic review.
Ruano-Ravina A, Pena-Gil C, Abu-Assi E, Raposeiras S, van 't Hof A, Meindersma E, Bossano Prescott EI, González-Juanatey JR
Int J Cardiol 2016 Nov 15;223:436-443. Epub 2016 Aug 13 doi: 10.1016/j.ijcard.2016.08.120. PMID: 27557484
Progestin-only contraception and thromboembolism: A systematic review.
Tepper NK, Whiteman MK, Marchbanks PA, James AH, Curtis KM
Contraception 2016 Dec;94(6):678-700. Epub 2016 May 3 doi: 10.1016/j.contraception.2016.04.014. PMID: 27153743Free PMC Article
beta Blockade after myocardial infarction: systematic review and meta regression analysis.
Freemantle N, Cleland J, Young P, Mason J, Harrison J
BMJ 1999 Jun 26;318(7200):1730-7. doi: 10.1136/bmj.318.7200.1730. PMID: 10381708Free PMC Article

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    Clinical resources

    Practice guidelines

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      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Curated

    • NICE, 2020
      UK NICE guideline NG185, Acute coronary syndromes, 2020

    Consumer resources

    Reviews

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