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Eosinophilic meningitis

MedGen UID:
509620
•Concept ID:
C0154652
•
Disease or Syndrome
Synonyms: Eosinophilic Meningitis; eosinophilic meningitis
SNOMED CT: Eosinophilic meningitis (25671008)
 
Monarch Initiative: MONDO:0001015

Definition

Meningitis in which eosinophils predominate in the cerebrospinal fluid. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEosinophilic meningitis

Professional guidelines

PubMed

Angiostrongylus cantonensis in travelers: clinical manifestations, diagnosis, and treatment.
Ansdell V, Wattanagoon Y
Curr Opin Infect Dis 2018 Oct;31(5):399-408. doi: 10.1097/QCO.0000000000000481. PMID: 30138142
Guest Editor's message: Eosinophilic meningitis caused by Angiostrongylus cantonensis, the rat lungworm: biology, distribution, epidemiology, detection, diagnosis, treatment, and management.
Cowie RH
Hawaii J Med Public Health 2013 Jun;72(6 Suppl 2):3-4. PMID: 23901370Free PMC Article
Treatment of angiostrongyliasis.
Sawanyawisuth K, Sawanyawisuth K
Trans R Soc Trop Med Hyg 2008 Oct;102(10):990-6. Epub 2008 May 27 doi: 10.1016/j.trstmh.2008.04.021. PMID: 18501934

Recent clinical studies

Etiology

Diagnostic importance of eosinophilic meningitis in HIV-positive and HIV-negative patients.
de Almeida SM, de Souza CV, Pletsch L, Kovaliuk SK, Hummelgen A Jr, Piseta VV, Haurani CRA, Mendes IS, Yamada EY, Fröehner IS, Pinheiro RL, de Fátima Gabriel A, Cogo LL, Lira LNA, Kim MSM, Singer GMB
J Neurovirol 2019 Jun;25(3):331-341. Epub 2019 Jan 23 doi: 10.1007/s13365-019-00722-5. PMID: 30673998
Corticosteroids for parasitic eosinophilic meningitis.
Thanaviratananich S, Thanaviratananich S, Ngamjarus C
Cochrane Database Syst Rev 2015 Feb 17;2015(2):CD009088. doi: 10.1002/14651858.CD009088.pub3. PMID: 25687750Free PMC Article
Eosinophilic meningitis caused by Angiostrongylus cantonensis--a neglected disease with escalating importance.
Eamsobhana P
Trop Biomed 2014 Dec;31(4):569-78. PMID: 25776582
Eosinophilic meningitis.
Sawanyawisuth K, Chotmongkol V
Handb Clin Neurol 2013;114:207-15. doi: 10.1016/B978-0-444-53490-3.00015-7. PMID: 23829911
Corticosteroids for parasitic eosinophilic meningitis.
Thanaviratananich S, Thanaviratananich S, Ngamjarus C
Cochrane Database Syst Rev 2012 Oct 17;10:CD009088. doi: 10.1002/14651858.CD009088.pub2. PMID: 23076953

Diagnosis

Tropical spastic paraparesis.
Román GC
Handb Clin Neurol 2023;196:149-156. doi: 10.1016/B978-0-323-98817-9.00026-0. PMID: 37620067
Pediatric angiostrongyliasis.
Lombard F, Basset D, Cambonie G, Bastien P, Jeziorski E
Med Sante Trop 2018 Feb 1;28(1):76-81. doi: 10.1684/mst.2018.0756. PMID: 29616650
Tropical myelopathies.
Román GC
Handb Clin Neurol 2014;121:1521-48. doi: 10.1016/B978-0-7020-4088-7.00102-4. PMID: 24365434
Eosinophilic meningitis.
Sawanyawisuth K, Chotmongkol V
Handb Clin Neurol 2013;114:207-15. doi: 10.1016/B978-0-444-53490-3.00015-7. PMID: 23829911
Eosinophilic meningitis.
Lo Re V 3rd, Gluckman SJ
Am J Med 2003 Feb 15;114(3):217-23. doi: 10.1016/s0002-9343(02)01495-x. PMID: 12637136

Therapy

Angiostrongylus cantonensis in travelers: clinical manifestations, diagnosis, and treatment.
Ansdell V, Wattanagoon Y
Curr Opin Infect Dis 2018 Oct;31(5):399-408. doi: 10.1097/QCO.0000000000000481. PMID: 30138142
Corticosteroids for parasitic eosinophilic meningitis.
Thanaviratananich S, Thanaviratananich S, Ngamjarus C
Cochrane Database Syst Rev 2015 Feb 17;2015(2):CD009088. doi: 10.1002/14651858.CD009088.pub3. PMID: 25687750Free PMC Article
Corticosteroids for parasitic eosinophilic meningitis.
Thanaviratananich S, Thanaviratananich S, Ngamjarus C
Cochrane Database Syst Rev 2012 Oct 17;10:CD009088. doi: 10.1002/14651858.CD009088.pub2. PMID: 23076953
Human Angiostrongylus cantonensis: an update.
Wang QP, Wu ZD, Wei J, Owen RL, Lun ZR
Eur J Clin Microbiol Infect Dis 2012 Apr;31(4):389-95. Epub 2011 Jul 5 doi: 10.1007/s10096-011-1328-5. PMID: 21725905
Treatment of angiostrongyliasis.
Sawanyawisuth K, Sawanyawisuth K
Trans R Soc Trop Med Hyg 2008 Oct;102(10):990-6. Epub 2008 May 27 doi: 10.1016/j.trstmh.2008.04.021. PMID: 18501934

Prognosis

Corticosteroids for parasitic eosinophilic meningitis.
Thanaviratananich S, Thanaviratananich S, Ngamjarus C
Cochrane Database Syst Rev 2015 Feb 17;2015(2):CD009088. doi: 10.1002/14651858.CD009088.pub3. PMID: 25687750Free PMC Article
Central nervous system manifestations of Angiostrongylus cantonensis infection.
Martins YC, Tanowitz HB, Kazacos KR
Acta Trop 2015 Jan;141(Pt A):46-53. Epub 2014 Oct 13 doi: 10.1016/j.actatropica.2014.10.002. PMID: 25312338Free PMC Article
Angiostrongyliasis in Thailand: epidemiology and laboratory investigations.
Eamsobhana P
Hawaii J Med Public Health 2013 Jun;72(6 Suppl 2):28-32. PMID: 23901379Free PMC Article
Corticosteroids for parasitic eosinophilic meningitis.
Thanaviratananich S, Thanaviratananich S, Ngamjarus C
Cochrane Database Syst Rev 2012 Oct 17;10:CD009088. doi: 10.1002/14651858.CD009088.pub2. PMID: 23076953
Angiostrongylus (Parastrongylus) eosinophilic meningitis.
Koo J, Pien F, Kliks MM
Rev Infect Dis 1988 Nov-Dec;10(6):1155-62. doi: 10.1093/clinids/10.6.1155. PMID: 3060943

Clinical prediction guides

RPAcan3990: an Ultrasensitive Recombinase Polymerase Assay To Detect Angiostrongylus cantonensis DNA.
Sears WJ, Qvarnstrom Y, Nutman TB
J Clin Microbiol 2021 Aug 18;59(9):e0118521. doi: 10.1128/JCM.01185-21. PMID: 34132583Free PMC Article
MicroRNA miR-155-5p knockdown attenuates Angiostrongylus cantonensis-induced eosinophilic meningitis by downregulating MMP9 and TSLP proteins.
Zhou X, Zhang J, Liu J, Guo J, Wei Y, Li J, He P, Lan T, Peng L, Li H
Int J Parasitol 2021 Jan;51(1):13-22. Epub 2020 Sep 20 doi: 10.1016/j.ijpara.2020.07.013. PMID: 32966836
Physiology and immunity of the invasive giant African snail, Achatina (Lissachatina) fulica, intermediate host of Angiostrongylus cantonensis.
Lima MG, Augusto RC, Pinheiro J, Thiengo SC
Dev Comp Immunol 2020 Apr;105:103579. Epub 2019 Dec 23 doi: 10.1016/j.dci.2019.103579. PMID: 31877327
Magnetic resonance imaging findings and clinical manifestations in cerebral angiostrongyliasis from Dali, China.
Yang B, Yang L, Chen Y, Lu G
Brain Behav 2019 Aug;9(8):e01361. Epub 2019 Jul 17 doi: 10.1002/brb3.1361. PMID: 31313505Free PMC Article
Corticosteroids for parasitic eosinophilic meningitis.
Thanaviratananich S, Thanaviratananich S, Ngamjarus C
Cochrane Database Syst Rev 2015 Feb 17;2015(2):CD009088. doi: 10.1002/14651858.CD009088.pub3. PMID: 25687750Free PMC Article

Recent systematic reviews

Chronic eosinophilic meningitis as a manifestation of isolated spinal neurocysticercosis: A rare case and a review of literature.
Shashidhar A, Savardekar AR, Mundlamuri RC, Netravathi M, Nalini A, Chickabasaviah YT, Arivazhagan A, Rao MB
Neurol India 2018 Mar-Apr;66(2):561-564. doi: 10.4103/0028-3886.227297. PMID: 29547198
Corticosteroids for parasitic eosinophilic meningitis.
Thanaviratananich S, Thanaviratananich S, Ngamjarus C
Cochrane Database Syst Rev 2015 Feb 17;2015(2):CD009088. doi: 10.1002/14651858.CD009088.pub3. PMID: 25687750Free PMC Article
Corticosteroids for parasitic eosinophilic meningitis.
Thanaviratananich S, Thanaviratananich S, Ngamjarus C
Cochrane Database Syst Rev 2012 Oct 17;10:CD009088. doi: 10.1002/14651858.CD009088.pub2. PMID: 23076953

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