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Postsurgical hypothyroidism

MedGen UID:
509534
•Concept ID:
C0154157
•
Disease or Syndrome
Synonyms: Hypothyroidism after surgery; post-surgical hypothyroidism; Postoperative hypothyroidism; postoperative hypothyroidism; postsurgical hypothyroidism
SNOMED CT: Postoperative hypothyroidism (27059002); Postsurgical hypothyroidism (27059002); Hypothyroidism after surgery (27059002)
 
Monarch Initiative: MONDO:0002002

Professional guidelines

PubMed

Hypothyroidisim following hemithyroidectomy: incidence, risk factors, and management.
McHenry CR, Slusarczyk SJ
Surgery 2000 Dec;128(6):994-8. doi: 10.1067/msy.2000.110242. PMID: 11114634

Recent clinical studies

Etiology

Preliminary Results of a Double-Blind Randomized Controlled Trial Evaluating the Cardiometabolic Effects of Levothyroxine and Liothyronine Compared to Levothyroxine with Placebo in Athyreotic Low-Risk Thyroid Cancer Patients.
Biondi B, Pucci M, Pontieri G, Formisano P, Esposito R
Thyroid 2023 Dec;33(12):1402-1413. Epub 2023 Oct 23 doi: 10.1089/thy.2023.0135. PMID: 37725587
Attaining biochemical euthyroidism early after total thyroidectomy in Graves' disease may lower long-term morbidity risk.
Liu X, Wong CKH, Chan WWL, Tang EHM, Woo YC, Liu SYW, Lam CLK, Lang BHH
BJS Open 2022 Jul 7;6(4) doi: 10.1093/bjsopen/zrac079. PMID: 35822337Free PMC Article
Postoperative thyroid hormone supplementation rates following thyroid lobectomy.
Wilson M, Patel A, Goldner W, Baker J, Sayed Z, Fingeret AL
Am J Surg 2021 Apr;221(4):804-808. Epub 2020 Jul 9 doi: 10.1016/j.amjsurg.2020.07.001. PMID: 32682499
Postoperative thyroid hormone supplementation rates following thyroid lobectomy.
Wilson M, Patel A, Goldner W, Baker J, Sayed Z, Fingeret AL
Am J Surg 2020 Nov;220(5):1169-1173. Epub 2020 Jul 1 doi: 10.1016/j.amjsurg.2020.06.052. PMID: 32684294
Thyroid carcinoma.
Sherman SI
Lancet 2003 Feb 8;361(9356):501-11. doi: 10.1016/s0140-6736(03)12488-9. PMID: 12583960

Diagnosis

Preliminary Results of a Double-Blind Randomized Controlled Trial Evaluating the Cardiometabolic Effects of Levothyroxine and Liothyronine Compared to Levothyroxine with Placebo in Athyreotic Low-Risk Thyroid Cancer Patients.
Biondi B, Pucci M, Pontieri G, Formisano P, Esposito R
Thyroid 2023 Dec;33(12):1402-1413. Epub 2023 Oct 23 doi: 10.1089/thy.2023.0135. PMID: 37725587
The Role of Serum Procalcitonin in Predicting Bacterial Sepsis in Patients With Hypothyroidism.
Shirali AS, Wu JX, Zhu CY, Ocampo A, Tseng CH, Du L, Livhits MJ, Leung AM, Yeh MW
J Clin Endocrinol Metab 2019 Dec 1;104(12):5915-5922. doi: 10.1210/jc.2019-01082. PMID: 31361312
Selective or radical surgical strategy in functional autonomy of the thyroid in endemic areas.
Pandev R, Kouzi A, Cherkezov G, Damyanov D
Khirurgiia (Sofiia) 2013;(2):12-4. PMID: 24151744
Prediction of hypothyroidism after hemithyroidectomy: a biochemical and pathological analysis.
Koh YW, Lee SW, Choi EC, Lee JD, Mok JO, Kim HK, Koh ES, Lee JY, Kim SC
Eur Arch Otorhinolaryngol 2008 Apr;265(4):453-7. Epub 2007 Nov 3 doi: 10.1007/s00405-007-0513-8. PMID: 17978827
Thyroid carcinoma.
Sherman SI
Lancet 2003 Feb 8;361(9356):501-11. doi: 10.1016/s0140-6736(03)12488-9. PMID: 12583960

Therapy

Preliminary Results of a Double-Blind Randomized Controlled Trial Evaluating the Cardiometabolic Effects of Levothyroxine and Liothyronine Compared to Levothyroxine with Placebo in Athyreotic Low-Risk Thyroid Cancer Patients.
Biondi B, Pucci M, Pontieri G, Formisano P, Esposito R
Thyroid 2023 Dec;33(12):1402-1413. Epub 2023 Oct 23 doi: 10.1089/thy.2023.0135. PMID: 37725587
Attaining biochemical euthyroidism early after total thyroidectomy in Graves' disease may lower long-term morbidity risk.
Liu X, Wong CKH, Chan WWL, Tang EHM, Woo YC, Liu SYW, Lam CLK, Lang BHH
BJS Open 2022 Jul 7;6(4) doi: 10.1093/bjsopen/zrac079. PMID: 35822337Free PMC Article
Postoperative thyroid hormone supplementation rates following thyroid lobectomy.
Wilson M, Patel A, Goldner W, Baker J, Sayed Z, Fingeret AL
Am J Surg 2021 Apr;221(4):804-808. Epub 2020 Jul 9 doi: 10.1016/j.amjsurg.2020.07.001. PMID: 32682499
Self-Reported Allergy to Thyroid Replacement Therapy: A Multicenter Retrospective Chart Review.
Chamorro-Pareja N, Carrillo-Martin I, Haehn DA, Westphal SA, Park MA, Bernet VJ, Gonzalez-Estrada A
Endocr Pract 2020 Jul;26(7):761-767. Epub 2020 Nov 24 doi: 10.4158/EP-2019-0488. PMID: 33471645
Postoperative thyroid hormone supplementation rates following thyroid lobectomy.
Wilson M, Patel A, Goldner W, Baker J, Sayed Z, Fingeret AL
Am J Surg 2020 Nov;220(5):1169-1173. Epub 2020 Jul 1 doi: 10.1016/j.amjsurg.2020.06.052. PMID: 32684294

Prognosis

Self-Reported Allergy to Thyroid Replacement Therapy: A Multicenter Retrospective Chart Review.
Chamorro-Pareja N, Carrillo-Martin I, Haehn DA, Westphal SA, Park MA, Bernet VJ, Gonzalez-Estrada A
Endocr Pract 2020 Jul;26(7):761-767. Epub 2020 Nov 24 doi: 10.4158/EP-2019-0488. PMID: 33471645
The Role of Serum Procalcitonin in Predicting Bacterial Sepsis in Patients With Hypothyroidism.
Shirali AS, Wu JX, Zhu CY, Ocampo A, Tseng CH, Du L, Livhits MJ, Leung AM, Yeh MW
J Clin Endocrinol Metab 2019 Dec 1;104(12):5915-5922. doi: 10.1210/jc.2019-01082. PMID: 31361312
Pancytopenia: a rare complication of Graves' disease.
Garla VV, Abdul Salim S, Yanes-Cardozo LL
BMJ Case Rep 2018 Mar 9;2018 doi: 10.1136/bcr-2017-223887. PMID: 29525760Free PMC Article
Prediction of hypothyroidism after hemithyroidectomy: a biochemical and pathological analysis.
Koh YW, Lee SW, Choi EC, Lee JD, Mok JO, Kim HK, Koh ES, Lee JY, Kim SC
Eur Arch Otorhinolaryngol 2008 Apr;265(4):453-7. Epub 2007 Nov 3 doi: 10.1007/s00405-007-0513-8. PMID: 17978827
Thyroid carcinoma.
Sherman SI
Lancet 2003 Feb 8;361(9356):501-11. doi: 10.1016/s0140-6736(03)12488-9. PMID: 12583960

Clinical prediction guides

Preliminary Results of a Double-Blind Randomized Controlled Trial Evaluating the Cardiometabolic Effects of Levothyroxine and Liothyronine Compared to Levothyroxine with Placebo in Athyreotic Low-Risk Thyroid Cancer Patients.
Biondi B, Pucci M, Pontieri G, Formisano P, Esposito R
Thyroid 2023 Dec;33(12):1402-1413. Epub 2023 Oct 23 doi: 10.1089/thy.2023.0135. PMID: 37725587
Self-Reported Allergy to Thyroid Replacement Therapy: A Multicenter Retrospective Chart Review.
Chamorro-Pareja N, Carrillo-Martin I, Haehn DA, Westphal SA, Park MA, Bernet VJ, Gonzalez-Estrada A
Endocr Pract 2020 Jul;26(7):761-767. Epub 2020 Nov 24 doi: 10.4158/EP-2019-0488. PMID: 33471645
The Role of Serum Procalcitonin in Predicting Bacterial Sepsis in Patients With Hypothyroidism.
Shirali AS, Wu JX, Zhu CY, Ocampo A, Tseng CH, Du L, Livhits MJ, Leung AM, Yeh MW
J Clin Endocrinol Metab 2019 Dec 1;104(12):5915-5922. doi: 10.1210/jc.2019-01082. PMID: 31361312
Concurrent Hypoparathyroidism Is Associated With Impaired Physical Function and Quality of Life in Hypothyroidism.
Sikjaer T, Moser E, Rolighed L, Underbjerg L, Bislev LS, Mosekilde L, Rejnmark L
J Bone Miner Res 2016 Jul;31(7):1440-8. Epub 2016 Mar 31 doi: 10.1002/jbmr.2812. PMID: 26865527
Prediction of hypothyroidism after hemithyroidectomy: a biochemical and pathological analysis.
Koh YW, Lee SW, Choi EC, Lee JD, Mok JO, Kim HK, Koh ES, Lee JY, Kim SC
Eur Arch Otorhinolaryngol 2008 Apr;265(4):453-7. Epub 2007 Nov 3 doi: 10.1007/s00405-007-0513-8. PMID: 17978827

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