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Malignant Neoplasm of Body of Penis

MedGen UID:
509338
•Concept ID:
C0153600
•
Neoplastic Process
Synonyms: Cancer of body of penis; Malignant neoplasm of body of penis; Malignant tumor of body of penis; Malignant tumor of shaft of penis
SNOMED CT: Malignant tumor of body of penis (188230001); Malignant neoplasm of body of penis (188230001); Cancer of body of penis (188230001); Malignant tumor of shaft of penis (188230001)

Definition

Evidence of a malignant neoplasm of the body of the penis. [from NCI]

Professional guidelines

PubMed

Current Disease Management of Primary Urethral Carcinoma.
Janisch F, Abufaraj M, Fajkovic H, Kimura S, Iwata T, Nyirady P, Rink M, Shariat SF
Eur Urol Focus 2019 Sep;5(5):722-734. Epub 2019 Jul 13 doi: 10.1016/j.euf.2019.07.001. PMID: 31307949
Penile Cancer: Contemporary Lymph Node Management.
O'Brien JS, Perera M, Manning T, Bozin M, Cabarkapa S, Chen E, Lawrentschuk N
J Urol 2017 Jun;197(6):1387-1395. Epub 2017 Jan 20 doi: 10.1016/j.juro.2017.01.059. PMID: 28115191
Endoscopic Treatment of Vesicourethral Stenosis after Radical Prostatectomy: Outcomes and Predictors of Success.
LaBossiere JR, Cheung D, Rourke K
J Urol 2016 May;195(5):1495-1500. Epub 2015 Dec 21 doi: 10.1016/j.juro.2015.12.073. PMID: 26719028

Recent clinical studies

Etiology

Pathology of Squamous Cell Carcinoma of the Penis: Back to Square One.
Sanchez DF, Oliveira P
Urol Clin North Am 2024 Aug;51(3):313-325. Epub 2024 Apr 12 doi: 10.1016/j.ucl.2024.03.003. PMID: 38925734
Prognostic predictors of lymph node metastasis in penile cancer: a systematic review.
Zekan DS, Dahman A, Hajiran AJ, Luchey AM, Chahoud J, Spiess PE
Int Braz J Urol 2021 Sep-Oct;47(5):943-956. doi: 10.1590/S1677-5538.IBJU.2020.0959. PMID: 33650835Free PMC Article
Prostate Stereotactic Body Radiation Therapy: An Overview of Toxicity and Dose Response.
Wang K, Mavroidis P, Royce TJ, Falchook AD, Collins SP, Sapareto S, Sheets NC, Fuller DB, El Naqa I, Yorke E, Grimm J, Jackson A, Chen RC
Int J Radiat Oncol Biol Phys 2021 May 1;110(1):237-248. Epub 2020 Dec 22 doi: 10.1016/j.ijrobp.2020.09.054. PMID: 33358229Free PMC Article
TGF-β and microRNA Interplay in Genitourinary Cancers.
Boguslawska J, Kryst P, Poletajew S, Piekielko-Witkowska A
Cells 2019 Dec 12;8(12) doi: 10.3390/cells8121619. PMID: 31842336Free PMC Article
Pathophysiology and Contributing Factors in Postprostatectomy Incontinence: A Review.
Heesakkers J, Farag F, Bauer RM, Sandhu J, De Ridder D, Stenzl A
Eur Urol 2017 Jun;71(6):936-944. Epub 2016 Oct 6 doi: 10.1016/j.eururo.2016.09.031. PMID: 27720536

Diagnosis

Papillomaviruses and cancer: commonalities and differences in HPV carcinogenesis at different sites of the body.
Egawa N
Int J Clin Oncol 2023 Aug;28(8):956-964. Epub 2023 May 18 doi: 10.1007/s10147-023-02340-y. PMID: 37199886Free PMC Article
Preputial melanoma.
Tchernev G, Temelkova I
Wien Med Wochenschr 2021 Feb;171(1-2):41-42. Epub 2020 May 7 doi: 10.1007/s10354-020-00751-4. PMID: 32382854
TGF-β and microRNA Interplay in Genitourinary Cancers.
Boguslawska J, Kryst P, Poletajew S, Piekielko-Witkowska A
Cells 2019 Dec 12;8(12) doi: 10.3390/cells8121619. PMID: 31842336Free PMC Article
Hepatic capsular retraction: An updated MR imaging review.
Panick CEP, Ward RD, Coppa C, Liu PS
Eur J Radiol 2019 Apr;113:15-23. Epub 2019 Jan 31 doi: 10.1016/j.ejrad.2019.01.037. PMID: 30927940
Penile cancer: organ-sparing surgery.
Pompeo AC, Zequi Sde C, Pompeo AS
Curr Opin Urol 2015 Mar;25(2):121-8. doi: 10.1097/MOU.0000000000000149. PMID: 25599291

Therapy

Prostate Stereotactic Body Radiation Therapy: An Overview of Toxicity and Dose Response.
Wang K, Mavroidis P, Royce TJ, Falchook AD, Collins SP, Sapareto S, Sheets NC, Fuller DB, El Naqa I, Yorke E, Grimm J, Jackson A, Chen RC
Int J Radiat Oncol Biol Phys 2021 May 1;110(1):237-248. Epub 2020 Dec 22 doi: 10.1016/j.ijrobp.2020.09.054. PMID: 33358229Free PMC Article
Review of optimal techniques for robotic-assisted radical prostatectomy.
Kasabwala K, Patel NA, Hu JC
Curr Opin Urol 2018 Mar;28(2):102-107. doi: 10.1097/MOU.0000000000000473. PMID: 29300208
Pathophysiology and Contributing Factors in Postprostatectomy Incontinence: A Review.
Heesakkers J, Farag F, Bauer RM, Sandhu J, De Ridder D, Stenzl A
Eur Urol 2017 Jun;71(6):936-944. Epub 2016 Oct 6 doi: 10.1016/j.eururo.2016.09.031. PMID: 27720536
Penile cancer and phallus preservation strategies: a review of current literature.
Zukiwskyj M, Daly P, Chung E
BJU Int 2013 Nov;112 Suppl 2:21-6. doi: 10.1111/bju.12205. PMID: 24127672
Monitoring of human papillomavirus vaccination.
Dillner J, Arbyn M, Unger E, Dillner L
Clin Exp Immunol 2011 Jan;163(1):17-25. Epub 2010 Nov 9 doi: 10.1111/j.1365-2249.2010.04268.x. PMID: 21062269Free PMC Article

Prognosis

Pathology of Squamous Cell Carcinoma of the Penis: Back to Square One.
Sanchez DF, Oliveira P
Urol Clin North Am 2024 Aug;51(3):313-325. Epub 2024 Apr 12 doi: 10.1016/j.ucl.2024.03.003. PMID: 38925734
Prognostic predictors of lymph node metastasis in penile cancer: a systematic review.
Zekan DS, Dahman A, Hajiran AJ, Luchey AM, Chahoud J, Spiess PE
Int Braz J Urol 2021 Sep-Oct;47(5):943-956. doi: 10.1590/S1677-5538.IBJU.2020.0959. PMID: 33650835Free PMC Article
Preputial melanoma.
Tchernev G, Temelkova I
Wien Med Wochenschr 2021 Feb;171(1-2):41-42. Epub 2020 May 7 doi: 10.1007/s10354-020-00751-4. PMID: 32382854
TGF-β and microRNA Interplay in Genitourinary Cancers.
Boguslawska J, Kryst P, Poletajew S, Piekielko-Witkowska A
Cells 2019 Dec 12;8(12) doi: 10.3390/cells8121619. PMID: 31842336Free PMC Article
Current Disease Management of Primary Urethral Carcinoma.
Janisch F, Abufaraj M, Fajkovic H, Kimura S, Iwata T, Nyirady P, Rink M, Shariat SF
Eur Urol Focus 2019 Sep;5(5):722-734. Epub 2019 Jul 13 doi: 10.1016/j.euf.2019.07.001. PMID: 31307949

Clinical prediction guides

Pathology of Squamous Cell Carcinoma of the Penis: Back to Square One.
Sanchez DF, Oliveira P
Urol Clin North Am 2024 Aug;51(3):313-325. Epub 2024 Apr 12 doi: 10.1016/j.ucl.2024.03.003. PMID: 38925734
Papillomaviruses and cancer: commonalities and differences in HPV carcinogenesis at different sites of the body.
Egawa N
Int J Clin Oncol 2023 Aug;28(8):956-964. Epub 2023 May 18 doi: 10.1007/s10147-023-02340-y. PMID: 37199886Free PMC Article
Clinical significance and risk factors of urethrovesical anastomotic urinary leakage following robot-assisted radical prostatectomy: a multi-institutional study.
Kakutani S, Takeshima Y, Yamada Y, Fujimura T, Nagamoto S, Enomoto Y, Hakozaki Y, Kimura N, Teshima T, Akiyama Y, Sato Y, Kawai T, Yamada D, Kume H
BMC Urol 2021 May 3;21(1):75. doi: 10.1186/s12894-021-00844-1. PMID: 33941161Free PMC Article
Prognostic predictors of lymph node metastasis in penile cancer: a systematic review.
Zekan DS, Dahman A, Hajiran AJ, Luchey AM, Chahoud J, Spiess PE
Int Braz J Urol 2021 Sep-Oct;47(5):943-956. doi: 10.1590/S1677-5538.IBJU.2020.0959. PMID: 33650835Free PMC Article
Cystoscopic findings: a video tutorial.
Lenherr SM, Crosby EC, Cameron AP
Int Urogynecol J 2015 Jun;26(6):921-3. Epub 2015 Jan 27 doi: 10.1007/s00192-014-2614-4. PMID: 25619539Free PMC Article

Recent systematic reviews

Prognostic predictors of lymph node metastasis in penile cancer: a systematic review.
Zekan DS, Dahman A, Hajiran AJ, Luchey AM, Chahoud J, Spiess PE
Int Braz J Urol 2021 Sep-Oct;47(5):943-956. doi: 10.1590/S1677-5538.IBJU.2020.0959. PMID: 33650835Free PMC Article
Prostate Stereotactic Body Radiation Therapy: An Overview of Toxicity and Dose Response.
Wang K, Mavroidis P, Royce TJ, Falchook AD, Collins SP, Sapareto S, Sheets NC, Fuller DB, El Naqa I, Yorke E, Grimm J, Jackson A, Chen RC
Int J Radiat Oncol Biol Phys 2021 May 1;110(1):237-248. Epub 2020 Dec 22 doi: 10.1016/j.ijrobp.2020.09.054. PMID: 33358229Free PMC Article
Tumor Control Probability Modeling and Systematic Review of the Literature of Stereotactic Body Radiation Therapy for Prostate Cancer.
Royce TJ, Mavroidis P, Wang K, Falchook AD, Sheets NC, Fuller DB, Collins SP, El Naqa I, Song DY, Ding GX, Nahum AE, Jackson A, Grimm J, Yorke E, Chen RC
Int J Radiat Oncol Biol Phys 2021 May 1;110(1):227-236. Epub 2020 Sep 6 doi: 10.1016/j.ijrobp.2020.08.014. PMID: 32900561Free PMC Article
Current Disease Management of Primary Urethral Carcinoma.
Janisch F, Abufaraj M, Fajkovic H, Kimura S, Iwata T, Nyirady P, Rink M, Shariat SF
Eur Urol Focus 2019 Sep;5(5):722-734. Epub 2019 Jul 13 doi: 10.1016/j.euf.2019.07.001. PMID: 31307949
Penile Cancer: Contemporary Lymph Node Management.
O'Brien JS, Perera M, Manning T, Bozin M, Cabarkapa S, Chen E, Lawrentschuk N
J Urol 2017 Jun;197(6):1387-1395. Epub 2017 Jan 20 doi: 10.1016/j.juro.2017.01.059. PMID: 28115191

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