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Malignant Neoplasm of Head of Pancreas

MedGen UID:
509298
•Concept ID:
C0153458
•
Neoplastic Process
Synonyms: Ca head of pancreas; Malignant tumor of head of pancreas
SNOMED CT: Ca head of pancreas (363419009); Malignant tumor of head of pancreas (363419009)

Definition

Evidence of a malignant neoplasm of the head of pancreas. [from NCI]

Professional guidelines

PubMed

The Diagnosis and Treatment of Ampullary Carcinoma.
Walter D, Schnitzbauer AA, Schulze F, Trojan J
Dtsch Arztebl Int 2023 Oct 27;120(43):729-735. doi: 10.3238/arztebl.m2023.0195. PMID: 37656482Free PMC Article
Ampullary Adenocarcinoma, Version 1.2023, NCCN Clinical Practice Guidelines in Oncology.
Chiorean EG, Chiaro MD, Tempero MA, Malafa MP, Benson AB, Cardin DB, Christensen JA, Chung V, Czito B, Dillhoff M, Donahue TR, Dotan E, Fountzilas C, Glazer ES, Hardacre J, Hawkins WG, Klute K, Ko AH, Kunstman JW, LoConte N, Lowy AM, Masood A, Moravek C, Nakakura EK, Narang AK, Nardo L, Obando J, Polanco PM, Reddy S, Reyngold M, Scaife C, Shen J, Truty MJ, Vollmer C, Wolff RA, Wolpin BM, Rn BM, Lubin S, Darlow SD
J Natl Compr Canc Netw 2023 Jul;21(7):753-782. doi: 10.6004/jnccn.2023.0034. PMID: 37433437
Controversies in the diagnosis and treatment of periampullary tumours.
Skórzewska M, Kurzawa P, Ciszewski T, Pelc Z, Polkowski WP
Surg Oncol 2022 Sep;44:101853. Epub 2022 Sep 14 doi: 10.1016/j.suronc.2022.101853. PMID: 36152420

Recent clinical studies

Etiology

A Multi-Institutional Phase 2 Trial of Ablative 5-Fraction Stereotactic Magnetic Resonance-Guided On-Table Adaptive Radiation Therapy for Borderline Resectable and Locally Advanced Pancreatic Cancer.
Parikh PJ, Lee P, Low DA, Kim J, Mittauer KE, Bassetti MF, Glide-Hurst CK, Raldow AC, Yang Y, Portelance L, Padgett KR, Zaki B, Zhang R, Kim H, Henke LE, Price AT, Mancias JD, Williams CL, Ng J, Pennell R, Pfeffer MR, Levin D, Mueller AC, Mooney KE, Kelly P, Shah AP, Boldrini L, Placidi L, Fuss M, Chuong MD
Int J Radiat Oncol Biol Phys 2023 Nov 15;117(4):799-808. Epub 2023 May 19 doi: 10.1016/j.ijrobp.2023.05.023. PMID: 37210048
Pancreatic head cancer - Current surgery techniques.
Olakowski M, Grudzińska E
Asian J Surg 2023 Jan;46(1):73-81. Epub 2022 Jun 6 doi: 10.1016/j.asjsur.2022.05.117. PMID: 35680512
Solid pseudopapilar neoplasm of the pancreas.
Salinas W, Marani M, Reimondez S, Alcaraz Á, Signorini F, Maraschio M, Giordano E, Obeide L
Cir Cir 2021;89(2):263-268. doi: 10.24875/CIRU.19001163. PMID: 33784288
Pancreatic resection for cancer-the Heidelberg technique.
Schneider M, Strobel O, Hackert T, Büchler MW
Langenbecks Arch Surg 2019 Dec;404(8):1017-1022. Epub 2019 Nov 14 doi: 10.1007/s00423-019-01839-1. PMID: 31728630
Peripancreatic schwannoma.
Kuo TC, Yang CY, Wu JM, Huang PH, Lai HS, Lee PH, Tien YW
Surgery 2013 Apr;153(4):542-8. Epub 2012 Oct 24 doi: 10.1016/j.surg.2012.08.066. PMID: 23102676

Diagnosis

The Diagnosis and Treatment of Ampullary Carcinoma.
Walter D, Schnitzbauer AA, Schulze F, Trojan J
Dtsch Arztebl Int 2023 Oct 27;120(43):729-735. doi: 10.3238/arztebl.m2023.0195. PMID: 37656482Free PMC Article
Solid pseudopapilar neoplasm of the pancreas.
Salinas W, Marani M, Reimondez S, Alcaraz Á, Signorini F, Maraschio M, Giordano E, Obeide L
Cir Cir 2021;89(2):263-268. doi: 10.24875/CIRU.19001163. PMID: 33784288
The surgical anatomy of the lymphatic system of the pancreas.
Cesmebasi A, Malefant J, Patel SD, Du Plessis M, Renna S, Tubbs RS, Loukas M
Clin Anat 2015 May;28(4):527-37. Epub 2014 Sep 15 doi: 10.1002/ca.22461. PMID: 25220721
Peripancreatic schwannoma.
Kuo TC, Yang CY, Wu JM, Huang PH, Lai HS, Lee PH, Tien YW
Surgery 2013 Apr;153(4):542-8. Epub 2012 Oct 24 doi: 10.1016/j.surg.2012.08.066. PMID: 23102676
Pancreatoblastoma.
Saif MW
JOP 2007 Jan 9;8(1):55-63. PMID: 17228135

Therapy

A Multi-Institutional Phase 2 Trial of Ablative 5-Fraction Stereotactic Magnetic Resonance-Guided On-Table Adaptive Radiation Therapy for Borderline Resectable and Locally Advanced Pancreatic Cancer.
Parikh PJ, Lee P, Low DA, Kim J, Mittauer KE, Bassetti MF, Glide-Hurst CK, Raldow AC, Yang Y, Portelance L, Padgett KR, Zaki B, Zhang R, Kim H, Henke LE, Price AT, Mancias JD, Williams CL, Ng J, Pennell R, Pfeffer MR, Levin D, Mueller AC, Mooney KE, Kelly P, Shah AP, Boldrini L, Placidi L, Fuss M, Chuong MD
Int J Radiat Oncol Biol Phys 2023 Nov 15;117(4):799-808. Epub 2023 May 19 doi: 10.1016/j.ijrobp.2023.05.023. PMID: 37210048
Appraising the causal role of smoking in multiple diseases: A systematic review and meta-analysis of Mendelian randomization studies.
Larsson SC, Burgess S
EBioMedicine 2022 Aug;82:104154. Epub 2022 Jul 8 doi: 10.1016/j.ebiom.2022.104154. PMID: 35816897Free PMC Article
Exercise for cancer cachexia in adults.
Grande AJ, Silva V, Sawaris Neto L, Teixeira Basmage JP, Peccin MS, Maddocks M
Cochrane Database Syst Rev 2021 Mar 18;3(3):CD010804. doi: 10.1002/14651858.CD010804.pub3. PMID: 33735441Free PMC Article
Human oral microbiome and prospective risk for pancreatic cancer: a population-based nested case-control study.
Fan X, Alekseyenko AV, Wu J, Peters BA, Jacobs EJ, Gapstur SM, Purdue MP, Abnet CC, Stolzenberg-Solomon R, Miller G, Ravel J, Hayes RB, Ahn J
Gut 2018 Jan;67(1):120-127. Epub 2016 Oct 14 doi: 10.1136/gutjnl-2016-312580. PMID: 27742762Free PMC Article
Radiation Therapy Oncology Group consensus panel guidelines for the delineation of the clinical target volume in the postoperative treatment of pancreatic head cancer.
Goodman KA, Regine WF, Dawson LA, Ben-Josef E, Haustermans K, Bosch WR, Turian J, Abrams RA
Int J Radiat Oncol Biol Phys 2012 Jul 1;83(3):901-8. Epub 2012 Apr 5 doi: 10.1016/j.ijrobp.2012.01.022. PMID: 22483737Free PMC Article

Prognosis

The microbiome and rise of early-onset cancers: knowledge gaps and research opportunities.
Mima K, Hamada T, Inamura K, Baba H, Ugai T, Ogino S
Gut Microbes 2023 Dec;15(2):2269623. Epub 2023 Oct 30 doi: 10.1080/19490976.2023.2269623. PMID: 37902043Free PMC Article
The Diagnosis and Treatment of Ampullary Carcinoma.
Walter D, Schnitzbauer AA, Schulze F, Trojan J
Dtsch Arztebl Int 2023 Oct 27;120(43):729-735. doi: 10.3238/arztebl.m2023.0195. PMID: 37656482Free PMC Article
Ampullary Adenocarcinoma, Version 1.2023, NCCN Clinical Practice Guidelines in Oncology.
Chiorean EG, Chiaro MD, Tempero MA, Malafa MP, Benson AB, Cardin DB, Christensen JA, Chung V, Czito B, Dillhoff M, Donahue TR, Dotan E, Fountzilas C, Glazer ES, Hardacre J, Hawkins WG, Klute K, Ko AH, Kunstman JW, LoConte N, Lowy AM, Masood A, Moravek C, Nakakura EK, Narang AK, Nardo L, Obando J, Polanco PM, Reddy S, Reyngold M, Scaife C, Shen J, Truty MJ, Vollmer C, Wolff RA, Wolpin BM, Rn BM, Lubin S, Darlow SD
J Natl Compr Canc Netw 2023 Jul;21(7):753-782. doi: 10.6004/jnccn.2023.0034. PMID: 37433437
Peripancreatic schwannoma.
Kuo TC, Yang CY, Wu JM, Huang PH, Lai HS, Lee PH, Tien YW
Surgery 2013 Apr;153(4):542-8. Epub 2012 Oct 24 doi: 10.1016/j.surg.2012.08.066. PMID: 23102676
Pancreatoblastoma.
Saif MW
JOP 2007 Jan 9;8(1):55-63. PMID: 17228135

Clinical prediction guides

Malignant Solid Pseudopapillary Neoplasm of the Pancreas: An Orthogonal Analysis.
Fleming AM, Hendrick LE, Yakoub D, Abdelhafeez H, Deneve JL, Langham MR Jr, Glazer ES, Davidoff AM, Merchant NB, Dickson PV, Murphy AJ
Ann Surg Oncol 2024 Jan;31(1):475-487. Epub 2023 Sep 28 doi: 10.1245/s10434-023-14343-0. PMID: 37768414
Clinical outcomes of minimally invasive duodenum-preserving pancreatic head resection.
Zu G, Chen W, Wu D, Zhang Y, Chen X
BMC Surg 2023 Sep 21;23(1):288. doi: 10.1186/s12893-023-02170-9. PMID: 37735367Free PMC Article
Clinical and Histological Basis of Adenosquamous Carcinoma of the Pancreas: A 30-year Experience.
Moslim MA, Lefton MD, Ross EA, Mackrides N, Reddy SS
J Surg Res 2021 Mar;259:350-356. Epub 2020 Nov 13 doi: 10.1016/j.jss.2020.09.024. PMID: 33190924Free PMC Article
PROGNOSIS IN CHRONIC PANCREATITIS AND CANCER WITH A PRIMARY LESION OF THE PANCREATIC HEAD.
Kryvoruchko IA, Teslenko MM, Andreyeshchev SA, Teslenko CM, Arsenyev AV
Klin Khir 2016 Oct;(10):34-9. PMID: 30479111
The surgical anatomy of the lymphatic system of the pancreas.
Cesmebasi A, Malefant J, Patel SD, Du Plessis M, Renna S, Tubbs RS, Loukas M
Clin Anat 2015 May;28(4):527-37. Epub 2014 Sep 15 doi: 10.1002/ca.22461. PMID: 25220721

Recent systematic reviews

Malignant Solid Pseudopapillary Neoplasm of the Pancreas: An Orthogonal Analysis.
Fleming AM, Hendrick LE, Yakoub D, Abdelhafeez H, Deneve JL, Langham MR Jr, Glazer ES, Davidoff AM, Merchant NB, Dickson PV, Murphy AJ
Ann Surg Oncol 2024 Jan;31(1):475-487. Epub 2023 Sep 28 doi: 10.1245/s10434-023-14343-0. PMID: 37768414
Appraising the causal role of smoking in multiple diseases: A systematic review and meta-analysis of Mendelian randomization studies.
Larsson SC, Burgess S
EBioMedicine 2022 Aug;82:104154. Epub 2022 Jul 8 doi: 10.1016/j.ebiom.2022.104154. PMID: 35816897Free PMC Article
Intraductal tubulopapillary neoplasm (ITPN) of the pancreas: a distinct entity among pancreatic tumors.
Paolino G, Esposito I, Hong SM, Basturk O, Mattiolo P, Kaneko T, Veronese N, Scarpa A, Adsay V, Luchini C
Histopathology 2022 Sep;81(3):297-309. Epub 2022 May 27 doi: 10.1111/his.14698. PMID: 35583805Free PMC Article
Pancreas-Preserving Total Duodenectomy: A Systematic Review.
Cantalejo-Díaz M, Ramia-Ángel JM, Palomares-Cano A, Serradilla-Martín M
Dig Surg 2021;38(3):186-197. Epub 2021 May 17 doi: 10.1159/000515718. PMID: 34000717
Exercise for cancer cachexia in adults.
Grande AJ, Silva V, Sawaris Neto L, Teixeira Basmage JP, Peccin MS, Maddocks M
Cochrane Database Syst Rev 2021 Mar 18;3(3):CD010804. doi: 10.1002/14651858.CD010804.pub3. PMID: 33735441Free PMC Article

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