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Malignant Neoplasm of Posterior Wall of Oropharynx

MedGen UID:
509273
•Concept ID:
C0153390
•
Neoplastic Process
Synonyms: Malignant neoplasm of posterior wall of oropharynx; Malignant tumor of posterior wall of oropharynx
SNOMED CT: Malignant tumor of posterior wall of oropharynx (187688008); Malignant neoplasm of posterior wall of oropharynx (187688008)

Definition

Evidence of a malignant neoplasm of the posterior wall of oropharynx. [from NCI]

Professional guidelines

PubMed

Oncological results of salvage treatment in patients with oropharynx carcinoma treated with radiotherapy.
León X, Neumann E, Holgado A, Vásquez R, Pujol A, Quer M
Acta Otorrinolaringol Esp (Engl Ed) 2024 Jan-Feb;75(1):8-16. Epub 2023 Jun 29 doi: 10.1016/j.otoeng.2023.06.008. PMID: 37393035
Psychosocial Oncology: Optimizing Outcomes through Interdisciplinary Care in Head and Neck Oncology.
Henry M
Curr Oncol 2023 Jul 19;30(7):6859-6861. doi: 10.3390/curroncol30070501. PMID: 37504361Free PMC Article
Oncological and functional outcomes of transoral surgery for the treatment of oropharyngeal cancer.
Chauhan P, Byrne H, Taylor E, Sheahan P
Ir J Med Sci 2015 Dec;184(4):825-30. Epub 2014 Aug 23 doi: 10.1007/s11845-014-1183-3. PMID: 25149079

Recent clinical studies

Etiology

Case series report: radiation-induced oropharyngeal carcinoma.
Salman S, Doweck I, Taha T, Billan S
Anticancer Drugs 2023 Feb 1;34(2):325-331. Epub 2022 Nov 15 doi: 10.1097/CAD.0000000000001411. PMID: 36730617
Determination of posterolateral oropharyngeal wall thickness and the potential implications for transoral surgical margins in tonsil cancer.
Tomblinson CM, Fletcher GP, Hu LS, Mi L, Howard BE, Nagel TH, Hinni ML, Hoxworth JM
Head Neck 2021 Jul;43(7):2185-2192. Epub 2021 Mar 29 doi: 10.1002/hed.26693. PMID: 33780072
The relationship between posterior pharyngeal wall thickness and swallowing function after radiation therapy.
Evangelista LM, Bayoumi A, Dyer BA, Shukla RP, Rao SD, Belafsky PC
Acta Otolaryngol 2020 Aug;140(8):693-696. Epub 2020 Apr 27 doi: 10.1080/00016489.2020.1752933. PMID: 32340517
Anatomic variations associated with antrochoanal polyps.
Gursoy M, Erdogan N, Cetinoglu YK, Dag F, Eren E, Uluc ME
Niger J Clin Pract 2019 May;22(5):603-608. doi: 10.4103/njcp.njcp_419_18. PMID: 31089013
Transoral oropharyngeal resection classification: Proposal of the SCORL working group.
Virós Porcuna D, Avilés Jurado F, Pollán Guisasola C, Ramírez Ruiz RD, García Lorenzo J, Tobed Secall M, Vilaseca González I, Costa González JM, Soteras Olle J, Casamitjana Claramunt F, Sumarroca Trouboul A, Hijano Esqué R, Viscasillas Pallàs G, Mañós Pujol M, Quer Agustí M
Acta Otorrinolaringol Esp (Engl Ed) 2017 Sep-Oct;68(5):289-293. Epub 2017 May 12 doi: 10.1016/j.otorri.2017.03.006. PMID: 28504187

Diagnosis

A collision tumor of nasopharyngeal carcinoma and primary mantle cell lymphoma in the nasopharynx: a case report and review of the literature.
Jiang M, Yuan XP, Zhang H, Li CQ, Mao YL, Chen WL
BMC Oral Health 2023 Sep 17;23(1):672. doi: 10.1186/s12903-023-03415-y. PMID: 37718438Free PMC Article
Case series report: radiation-induced oropharyngeal carcinoma.
Salman S, Doweck I, Taha T, Billan S
Anticancer Drugs 2023 Feb 1;34(2):325-331. Epub 2022 Nov 15 doi: 10.1097/CAD.0000000000001411. PMID: 36730617
Advance oropharyngeal mucoepidermoid carcinoma in a 9-year-old boy: A case report and review of literature.
Ajiya A, Shuaibu IY, Yahuza MA
Afr J Paediatr Surg 2022 Apr-Jun;19(2):105-108. doi: 10.4103/ajps.AJPS_133_20. PMID: 35017381Free PMC Article
Transoral endoscopic examination of head and neck region.
Hamada K, Ishihara R, Yamasaki Y, Akasaka T, Arao M, Iwatsubo T, Shichijo S, Matsuura N, Nakahira H, Kanesaka T, Yamamoto S, Takeuchi Y, Higashino K, Uedo N, Kawahara Y, Okada H
Dig Endosc 2018 Jul;30(4):516-521. Epub 2018 Apr 26 doi: 10.1111/den.13071. PMID: 29637617
Parapharyngeal liposarcoma: a case report.
Li H, Zhou X, Ran Q, Wang L
Diagn Pathol 2013 Mar 7;8:42. doi: 10.1186/1746-1596-8-42. PMID: 23497351Free PMC Article

Therapy

The relationship between posterior pharyngeal wall thickness and swallowing function after radiation therapy.
Evangelista LM, Bayoumi A, Dyer BA, Shukla RP, Rao SD, Belafsky PC
Acta Otolaryngol 2020 Aug;140(8):693-696. Epub 2020 Apr 27 doi: 10.1080/00016489.2020.1752933. PMID: 32340517
A phase 1 trial of Vorinostat in combination with concurrent chemoradiation therapy in the treatment of advanced staged head and neck squamous cell carcinoma.
Teknos TN, Grecula J, Agrawal A, Old MO, Ozer E, Carrau R, Kang S, Rocco J, Blakaj D, Diavolitsis V, Kumar B, Kumar P, Pan Q, Palettas M, Wei L, Baiocchi R, Savvides P
Invest New Drugs 2019 Aug;37(4):702-710. Epub 2018 Dec 19 doi: 10.1007/s10637-018-0696-4. PMID: 30569244
A long-term follow-up study after split-course irradiation with concurrent chemotherapy (carboplatin) for locally advanced head and neck cancer and a review of the literature.
Pradier O, Christiansen H, Ambrosch P, Kron M, Schmidberger H, Hess CF
ORL J Otorhinolaryngol Relat Spec 2004;66(6):325-31. doi: 10.1159/000081890. PMID: 15668532
Hodgkin's disease primarily involving the oropharynx: case report and review of the literature.
Aloulou S, Farhat H, Bosq J, Vanel D, Ribrag V, Turhan AG, Girinsky T, Fermé C
Hematol J 2002;3(3):164-7. doi: 10.1038/sj.thj.6200166. PMID: 12111654
Carcinoma of the soft palate and the posterior oropharyngeal wall.
Mak-Kregar S, Keus RB, Balm AJ, Hilgers FJ
Clin Otolaryngol Allied Sci 1994 Feb;19(1):22-7. doi: 10.1111/j.1365-2273.1994.tb01142.x. PMID: 8174296

Prognosis

Oncological results of salvage treatment in patients with oropharynx carcinoma treated with radiotherapy.
León X, Neumann E, Holgado A, Vásquez R, Pujol A, Quer M
Acta Otorrinolaringol Esp (Engl Ed) 2024 Jan-Feb;75(1):8-16. Epub 2023 Jun 29 doi: 10.1016/j.otoeng.2023.06.008. PMID: 37393035
A collision tumor of nasopharyngeal carcinoma and primary mantle cell lymphoma in the nasopharynx: a case report and review of the literature.
Jiang M, Yuan XP, Zhang H, Li CQ, Mao YL, Chen WL
BMC Oral Health 2023 Sep 17;23(1):672. doi: 10.1186/s12903-023-03415-y. PMID: 37718438Free PMC Article
A european multicenter study evaluating the flex robotic system in transoral robotic surgery.
Lang S, Mattheis S, Hasskamp P, Lawson G, Güldner C, Mandapathil M, Schuler P, Hoffmann T, Scheithauer M, Remacle M
Laryngoscope 2017 Feb;127(2):391-395. Epub 2016 Oct 26 doi: 10.1002/lary.26358. PMID: 27783427
Elective Nodal Irradiation and Patterns of Failure in Head and Neck Cancer After Primary Radiation Therapy.
Kjems J, Gothelf AB, Håkansson K, Specht L, Kristensen CA, Friborg J
Int J Radiat Oncol Biol Phys 2016 Mar 15;94(4):775-82. Epub 2016 Jan 6 doi: 10.1016/j.ijrobp.2015.12.380. PMID: 26972650
Pharyngeal wall carcinoma treated with radiotherapy: impact of treatment technique and fractionation.
Fein DA, Mendenhall WM, Parsons JT, Stringer SP, Cassisi NJ, Million RR
Int J Radiat Oncol Biol Phys 1993 Aug 1;26(5):751-7. doi: 10.1016/0360-3016(93)90488-h. PMID: 8344842

Clinical prediction guides

The relationship between posterior pharyngeal wall thickness and swallowing function after radiation therapy.
Evangelista LM, Bayoumi A, Dyer BA, Shukla RP, Rao SD, Belafsky PC
Acta Otolaryngol 2020 Aug;140(8):693-696. Epub 2020 Apr 27 doi: 10.1080/00016489.2020.1752933. PMID: 32340517
Transoral endoscopic examination of head and neck region.
Hamada K, Ishihara R, Yamasaki Y, Akasaka T, Arao M, Iwatsubo T, Shichijo S, Matsuura N, Nakahira H, Kanesaka T, Yamamoto S, Takeuchi Y, Higashino K, Uedo N, Kawahara Y, Okada H
Dig Endosc 2018 Jul;30(4):516-521. Epub 2018 Apr 26 doi: 10.1111/den.13071. PMID: 29637617
Nonuniform Distribution of High-risk Human Papillomavirus in Squamous Cell Carcinomas of the Oropharynx: Rethinking the Anatomic Boundaries of Oral and Oropharyngeal Carcinoma From an Oncologic HPV Perspective.
Gelwan E, Malm IJ, Khararjian A, Fakhry C, Bishop JA, Westra WH
Am J Surg Pathol 2017 Dec;41(12):1722-1728. doi: 10.1097/PAS.0000000000000929. PMID: 28877058
Elective Nodal Irradiation and Patterns of Failure in Head and Neck Cancer After Primary Radiation Therapy.
Kjems J, Gothelf AB, Håkansson K, Specht L, Kristensen CA, Friborg J
Int J Radiat Oncol Biol Phys 2016 Mar 15;94(4):775-82. Epub 2016 Jan 6 doi: 10.1016/j.ijrobp.2015.12.380. PMID: 26972650
Parapharyngeal liposarcoma: a case report.
Li H, Zhou X, Ran Q, Wang L
Diagn Pathol 2013 Mar 7;8:42. doi: 10.1186/1746-1596-8-42. PMID: 23497351Free PMC Article

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