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Gingivostomatitis

MedGen UID:
508414
•Concept ID:
C0149704
•
Disease or Syndrome
SNOMED CT: Gingivostomatitis (20607006)

Professional guidelines

PubMed

Diagnostic Methods and Management Strategies of Herpes Simplex and Herpes Zoster Infections.
Mehrmal S, Mojica R, Guo AM, Missall TA
Clin Geriatr Med 2024 Feb;40(1):147-175. Epub 2023 Oct 8 doi: 10.1016/j.cger.2023.09.003. PMID: 38000858
Supportive care and antiviral treatments in primary herpetic gingivostomatitis: a systematic review.
Coppola N, Cantile T, Adamo D, Canfora F, Baldares S, Riccitiello F, Musella G, Mignogna MDD, Leuci S
Clin Oral Investig 2023 Nov;27(11):6333-6344. Epub 2023 Sep 21 doi: 10.1007/s00784-023-05250-5. PMID: 37733027Free PMC Article
Congenital neutropenia: diagnosis, molecular bases and patient management.
Donadieu J, Fenneteau O, Beaupain B, Mahlaoui N, Chantelot CB
Orphanet J Rare Dis 2011 May 19;6:26. doi: 10.1186/1750-1172-6-26. PMID: 21595885Free PMC Article

Recent clinical studies

Etiology

Supportive care and antiviral treatments in primary herpetic gingivostomatitis: a systematic review.
Coppola N, Cantile T, Adamo D, Canfora F, Baldares S, Riccitiello F, Musella G, Mignogna MDD, Leuci S
Clin Oral Investig 2023 Nov;27(11):6333-6344. Epub 2023 Sep 21 doi: 10.1007/s00784-023-05250-5. PMID: 37733027Free PMC Article
Clinical features of gingivostomatitis due to primary infection of herpes simplex virus in children.
Huang CW, Hsieh CH, Lin MR, Huang YC
BMC Infect Dis 2020 Oct 20;20(1):782. doi: 10.1186/s12879-020-05509-2. PMID: 33081701Free PMC Article
Acyclovir for herpetic gingivostomatitis in children.
Goldman RD
Can Fam Physician 2016 May;62(5):403-4. PMID: 27255621Free PMC Article
WITHDRAWN: Acyclovir for treating primary herpetic gingivostomatitis.
Nasser M, Fedorowicz Z, Khoshnevisan MH, Shahiri Tabarestani M
Cochrane Database Syst Rev 2016 Jan 19;2016(1):CD006700. doi: 10.1002/14651858.CD006700.pub3. PMID: 26784280Free PMC Article
Glucose-6-phosphatase deficiency.
Froissart R, Piraud M, Boudjemline AM, Vianey-Saban C, Petit F, Hubert-Buron A, Eberschweiler PT, Gajdos V, Labrune P
Orphanet J Rare Dis 2011 May 20;6:27. doi: 10.1186/1750-1172-6-27. PMID: 21599942Free PMC Article

Diagnosis

Supportive care and antiviral treatments in primary herpetic gingivostomatitis: a systematic review.
Coppola N, Cantile T, Adamo D, Canfora F, Baldares S, Riccitiello F, Musella G, Mignogna MDD, Leuci S
Clin Oral Investig 2023 Nov;27(11):6333-6344. Epub 2023 Sep 21 doi: 10.1007/s00784-023-05250-5. PMID: 37733027Free PMC Article
Oral manifestations of COVID-19 disease: A review article.
Iranmanesh B, Khalili M, Amiri R, Zartab H, Aflatoonian M
Dermatol Ther 2021 Jan;34(1):e14578. Epub 2020 Dec 13 doi: 10.1111/dth.14578. PMID: 33236823Free PMC Article
The controversial natural history of oral herpes simplex virus type 1 infection.
Petti S, Lodi G
Oral Dis 2019 Nov;25(8):1850-1865. Epub 2019 Nov 27 doi: 10.1111/odi.13234. PMID: 31733122
Ulcerated Lesions of the Oral Mucosa: Clinical and Histologic Review.
Fitzpatrick SG, Cohen DM, Clark AN
Head Neck Pathol 2019 Mar;13(1):91-102. Epub 2019 Mar 7 doi: 10.1007/s12105-018-0981-8. PMID: 30701449Free PMC Article
Herpes Simplex Virus Type 1 infection: overview on relevant clinico-pathological features.
Arduino PG, Porter SR
J Oral Pathol Med 2008 Feb;37(2):107-21. doi: 10.1111/j.1600-0714.2007.00586.x. PMID: 18197856

Therapy

Supportive care and antiviral treatments in primary herpetic gingivostomatitis: a systematic review.
Coppola N, Cantile T, Adamo D, Canfora F, Baldares S, Riccitiello F, Musella G, Mignogna MDD, Leuci S
Clin Oral Investig 2023 Nov;27(11):6333-6344. Epub 2023 Sep 21 doi: 10.1007/s00784-023-05250-5. PMID: 37733027Free PMC Article
Clinical features of gingivostomatitis due to primary infection of herpes simplex virus in children.
Huang CW, Hsieh CH, Lin MR, Huang YC
BMC Infect Dis 2020 Oct 20;20(1):782. doi: 10.1186/s12879-020-05509-2. PMID: 33081701Free PMC Article
Acyclovir for herpetic gingivostomatitis in children.
Goldman RD
Can Fam Physician 2016 May;62(5):403-4. PMID: 27255621Free PMC Article
WITHDRAWN: Acyclovir for treating primary herpetic gingivostomatitis.
Nasser M, Fedorowicz Z, Khoshnevisan MH, Shahiri Tabarestani M
Cochrane Database Syst Rev 2016 Jan 19;2016(1):CD006700. doi: 10.1002/14651858.CD006700.pub3. PMID: 26784280Free PMC Article
Herpes Simplex Virus Type 1 infection: overview on relevant clinico-pathological features.
Arduino PG, Porter SR
J Oral Pathol Med 2008 Feb;37(2):107-21. doi: 10.1111/j.1600-0714.2007.00586.x. PMID: 18197856

Prognosis

Evaluation of stem-cell therapies in companion animal disease models: a concise review (2015-2023).
Williams ZJ, Pezzanite LM, Chow L, Rockow M, Dow SW
Stem Cells 2024 Aug 1;42(8):677-705. doi: 10.1093/stmcls/sxae034. PMID: 38795363
Congenital disseminated HSV-1 infection in preterm twins after primary gingivostomatitis of the mother: case report and review of the literature.
Mercolini F, Verdi F, Eisendle K, Messner H, Staffler A
Z Geburtshilfe Neonatol 2014 Dec;218(6):261-4. Epub 2014 Dec 17 doi: 10.1055/s-0034-1385854. PMID: 25518832
Glucose-6-phosphatase deficiency.
Froissart R, Piraud M, Boudjemline AM, Vianey-Saban C, Petit F, Hubert-Buron A, Eberschweiler PT, Gajdos V, Labrune P
Orphanet J Rare Dis 2011 May 20;6:27. doi: 10.1186/1750-1172-6-27. PMID: 21599942Free PMC Article
Management of primary herpetic gingivostomatitis in young children.
Faden H
Pediatr Emerg Care 2006 Apr;22(4):268-9. doi: 10.1097/01.pec.0000218982.46225.f5. PMID: 16651921
Primary herpes simplex virus type 1 gingivostomatitis during the second and third trimester of pregnancy: foetal and pregnancy outcome.
Pardo J, Yogev Y, Ben-Haroush A, Hod M, Amir J
Scand J Infect Dis 2004;36(3):179-81. doi: 10.1080/00365540410019354. PMID: 15119361

Clinical prediction guides

Low-Dose Rituximab for Bullous Pemphigoid. Protocol and Single-Center Experience.
Suárez-Carantoña C, Jiménez-Cauhé J, González-García A, Fernández-Guarino M, Asunción Ballester M
Actas Dermosifiliogr 2023 Jan;114(1):T62-T68. Epub 2022 Nov 8 doi: 10.1016/j.ad.2021.10.024. PMID: 36368587
Low-Dose Rituximab for Bullous Pemphigoid. Protocol and Single-Center Experience.
Suárez-Carantoña C, Jiménez-Cauhé J, González-García A, Fernández-Guarino M, Asunción Ballester M
Actas Dermosifiliogr 2023 Jan;114(1):62-68. Epub 2022 Jul 20 doi: 10.1016/j.ad.2021.10.018. PMID: 35868546
The perceived association of oral diseases and general pathology among doctors of different specialties.
Teodorescu IM, Preoteasa E, Preoteasa CT, Murariu-Măgureanu C, Teodorescu C
J Med Life 2022 Aug;15(8):1052-1057. doi: 10.25122/jml-2022-0021. PMID: 36188646Free PMC Article
ASSESSMENT OF ALLERGIES TO FOOD AND ADDITIVES IN PATIENTS WITH ANGIOEDEMA, BURNING MOUTH SYNDROME, CHEILITIS, GINGIVOSTOMATITIS, ORAL LICHENOID REACTIONS, AND PERIORAL DERMATITIS.
Domić I, Budmir J, Novak I, Mravak-Stipetić M, Lugović-Mihić L
Acta Clin Croat 2021 Jun;60(2):276-281. doi: 10.20471/acc.2021.60.02.14. PMID: 34744278Free PMC Article
Oral health status in children with acute lymphoblastic leukemia.
Javed F, Utreja A, Bello Correa FO, Al-Askar M, Hudieb M, Qayyum F, Al-Rasheed A, Almas K, Al-Hezaimi K
Crit Rev Oncol Hematol 2012 Sep;83(3):303-9. Epub 2011 Dec 3 doi: 10.1016/j.critrevonc.2011.11.003. PMID: 22137828

Recent systematic reviews

Supportive care and antiviral treatments in primary herpetic gingivostomatitis: a systematic review.
Coppola N, Cantile T, Adamo D, Canfora F, Baldares S, Riccitiello F, Musella G, Mignogna MDD, Leuci S
Clin Oral Investig 2023 Nov;27(11):6333-6344. Epub 2023 Sep 21 doi: 10.1007/s00784-023-05250-5. PMID: 37733027Free PMC Article
Oral manifestations related to malaria: A systematic review.
Shuai Y, Liu B, Zhou G, Rong L, Niu C, Jin L
Oral Dis 2021 Oct;27(7):1616-1620. Epub 2020 Aug 2 doi: 10.1111/odi.13549. PMID: 32657518
WITHDRAWN: Acyclovir for treating primary herpetic gingivostomatitis.
Nasser M, Fedorowicz Z, Khoshnevisan MH, Shahiri Tabarestani M
Cochrane Database Syst Rev 2016 Jan 19;2016(1):CD006700. doi: 10.1002/14651858.CD006700.pub3. PMID: 26784280Free PMC Article
Acyclovir for treating primary herpetic gingivostomatitis.
Nasser M, Fedorowicz Z, Khoshnevisan MH, Shahiri Tabarestani M
Cochrane Database Syst Rev 2008 Oct 8;(4):CD006700. doi: 10.1002/14651858.CD006700.pub2. PMID: 18843726

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