U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Symptoms of depression

MedGen UID:
39170
Concept ID:
C0086132
Mental or Behavioral Dysfunction
Synonyms: Depression, Emotional; Depressive Symptom; Depressive Symptoms; Emotional Depression; Symptom, Depressive
SNOMED CT: Symptoms of depression (394924000); Depressive symptoms (394924000)

Professional guidelines

PubMed

Czerwińska A, Pawłowski T
Psychiatr Pol 2020 Jun 30;54(3):453-466. doi: 10.12740/PP/OnlineFirst/105415. PMID: 33038880
Villa RF, Ferrari F, Moretti A
Pharmacol Ther 2018 Apr;184:131-144. Epub 2017 Nov 9 doi: 10.1016/j.pharmthera.2017.11.005. PMID: 29128343
Carek PJ, Laibstain SE, Carek SM
Int J Psychiatry Med 2011;41(1):15-28. doi: 10.2190/PM.41.1.c. PMID: 21495519

Recent clinical studies

Etiology

Chayadi E, Baes N, Kiropoulos L
PLoS One 2022;17(7):e0269519. Epub 2022 Jul 14 doi: 10.1371/journal.pone.0269519. PMID: 35834503Free PMC Article
Airaksinen J, Komulainen K, García-Velázquez R, Määttänen I, Gluschkoff K, Savelieva K, Jokela M
Compr Psychiatry 2021 Aug;109:152253. Epub 2021 Jun 12 doi: 10.1016/j.comppsych.2021.152253. PMID: 34147730
Watt JA, Goodarzi Z, Veroniki AA, Nincic V, Khan PA, Ghassemi M, Lai Y, Treister V, Thompson Y, Schneider R, Tricco AC, Straus SE
BMJ 2021 Mar 24;372:n532. doi: 10.1136/bmj.n532. PMID: 33762262Free PMC Article
Okun ML, Mancuso RA, Hobel CJ, Schetter CD, Coussons-Read M
J Behav Med 2018 Oct;41(5):703-710. Epub 2018 Jul 20 doi: 10.1007/s10865-018-9950-7. PMID: 30030650Free PMC Article
Buchberger B, Huppertz H, Krabbe L, Lux B, Mattivi JT, Siafarikas A
Psychoneuroendocrinology 2016 Aug;70:70-84. Epub 2016 Apr 29 doi: 10.1016/j.psyneuen.2016.04.019. PMID: 27179232

Diagnosis

van Barneveld E, Manders J, van Osch FHM, van Poll M, Visser L, van Hanegem N, Lim AC, Bongers MY, Leue C
J Womens Health (Larchmt) 2022 Feb;31(2):219-230. Epub 2021 Jun 2 doi: 10.1089/jwh.2021.0021. PMID: 34077695
Airaksinen J, Komulainen K, García-Velázquez R, Määttänen I, Gluschkoff K, Savelieva K, Jokela M
Compr Psychiatry 2021 Aug;109:152253. Epub 2021 Jun 12 doi: 10.1016/j.comppsych.2021.152253. PMID: 34147730
Watt JA, Goodarzi Z, Veroniki AA, Nincic V, Khan PA, Ghassemi M, Lai Y, Treister V, Thompson Y, Schneider R, Tricco AC, Straus SE
BMJ 2021 Mar 24;372:n532. doi: 10.1136/bmj.n532. PMID: 33762262Free PMC Article
Buchberger B, Huppertz H, Krabbe L, Lux B, Mattivi JT, Siafarikas A
Psychoneuroendocrinology 2016 Aug;70:70-84. Epub 2016 Apr 29 doi: 10.1016/j.psyneuen.2016.04.019. PMID: 27179232
Marantz S, Coates S
J Am Acad Child Adolesc Psychiatry 1991 Mar;30(2):310-5. doi: 10.1097/00004583-199103000-00022. PMID: 2016237

Therapy

Lewis BA, Schuver K, Dunsiger S, Samson L, Frayeh AL, Terrell CA, Ciccolo JT, Fischer J, Avery MD
BMC Pregnancy Childbirth 2021 Nov 22;21(1):785. doi: 10.1186/s12884-021-04257-8. PMID: 34802425Free PMC Article
Francis HM, Stevenson RJ, Chambers JR, Gupta D, Newey B, Lim CK
PLoS One 2019;14(10):e0222768. Epub 2019 Oct 9 doi: 10.1371/journal.pone.0222768. PMID: 31596866Free PMC Article
Sosa-Reina MD, Nunez-Nagy S, Gallego-Izquierdo T, Pecos-Martín D, Monserrat J, Álvarez-Mon M
Biomed Res Int 2017;2017:2356346. Epub 2017 Sep 20 doi: 10.1155/2017/2356346. PMID: 29291206Free PMC Article
Cooney GM, Dwan K, Greig CA, Lawlor DA, Rimer J, Waugh FR, McMurdo M, Mead GE
Cochrane Database Syst Rev 2013 Sep 12;2013(9):CD004366. doi: 10.1002/14651858.CD004366.pub6. PMID: 24026850Free PMC Article
Maratos AS, Gold C, Wang X, Crawford MJ
Cochrane Database Syst Rev 2008 Jan 23;(1):CD004517. doi: 10.1002/14651858.CD004517.pub2. PMID: 18254052

Prognosis

Yang L, Deng YT, Leng Y, Ou YN, Li YZ, Chen SD, He XY, Wu BS, Huang SY, Zhang YR, Kuo K, Feng W, Dong Q, Feng JF, Suckling J, Smith AD, Li F, Cheng W, Yu JT
Biol Psychiatry 2023 May 1;93(9):802-809. Epub 2022 Sep 5 doi: 10.1016/j.biopsych.2022.08.026. PMID: 36526487
Wang YH, Li JQ, Shi JF, Que JY, Liu JJ, Lappin JM, Leung J, Ravindran AV, Chen WQ, Qiao YL, Shi J, Lu L, Bao YP
Mol Psychiatry 2020 Jul;25(7):1487-1499. Epub 2019 Nov 19 doi: 10.1038/s41380-019-0595-x. PMID: 31745237
Francis HM, Stevenson RJ, Chambers JR, Gupta D, Newey B, Lim CK
PLoS One 2019;14(10):e0222768. Epub 2019 Oct 9 doi: 10.1371/journal.pone.0222768. PMID: 31596866Free PMC Article
Griffiths RR, Johnson MW, Carducci MA, Umbricht A, Richards WA, Richards BD, Cosimano MP, Klinedinst MA
J Psychopharmacol 2016 Dec;30(12):1181-1197. doi: 10.1177/0269881116675513. PMID: 27909165Free PMC Article
Desai SV, Law TJ, Needham DM
Crit Care Med 2011 Feb;39(2):371-9. doi: 10.1097/CCM.0b013e3181fd66e5. PMID: 20959786

Clinical prediction guides

Freitas PHB, Meireles AL, Ribeiro IKDS, Abreu MNS, Paula W, Cardoso CS
Rev Lat Am Enfermagem 2023;31:e3884. Epub 2023 Apr 17 doi: 10.1590/1518-8345.6315.3884. PMID: 37075384Free PMC Article
Patten RK, McIlvenna LC, Moreno-Asso A, Hiam D, Stepto NK, Rosenbaum S, Parker AG
Sci Rep 2023 Feb 21;13(1):3025. doi: 10.1038/s41598-023-29503-1. PMID: 36810865Free PMC Article
Chen B, Benzien C, Faria V, Ning Y, Cuevas M, Linke J, Croy I, Haehner A, Hummel T
ORL J Otorhinolaryngol Relat Spec 2021;83(3):135-143. Epub 2021 Mar 23 doi: 10.1159/000513751. PMID: 33756467
Okun ML, Mancuso RA, Hobel CJ, Schetter CD, Coussons-Read M
J Behav Med 2018 Oct;41(5):703-710. Epub 2018 Jul 20 doi: 10.1007/s10865-018-9950-7. PMID: 30030650Free PMC Article
Slykerman RF, Hood F, Wickens K, Thompson JMD, Barthow C, Murphy R, Kang J, Rowden J, Stone P, Crane J, Stanley T, Abels P, Purdie G, Maude R, Mitchell EA; Probiotic in Pregnancy Study Group
EBioMedicine 2017 Oct;24:159-165. Epub 2017 Sep 14 doi: 10.1016/j.ebiom.2017.09.013. PMID: 28943228Free PMC Article

Recent systematic reviews

Orgeta V, Leung P, Del-Pino-Casado R, Qazi A, Orrell M, Spector AE, Methley AM
Cochrane Database Syst Rev 2022 Apr 25;4(4):CD009125. doi: 10.1002/14651858.CD009125.pub3. PMID: 35466396Free PMC Article
Barberio B, Zamani M, Black CJ, Savarino EV, Ford AC
Lancet Gastroenterol Hepatol 2021 May;6(5):359-370. Epub 2021 Mar 12 doi: 10.1016/S2468-1253(21)00014-5. PMID: 33721557
Sosa-Reina MD, Nunez-Nagy S, Gallego-Izquierdo T, Pecos-Martín D, Monserrat J, Álvarez-Mon M
Biomed Res Int 2017;2017:2356346. Epub 2017 Sep 20 doi: 10.1155/2017/2356346. PMID: 29291206Free PMC Article
Nascimento SL, Surita FG, Cecatti JG
Curr Opin Obstet Gynecol 2012 Dec;24(6):387-94. doi: 10.1097/GCO.0b013e328359f131. PMID: 23014142
Maratos AS, Gold C, Wang X, Crawford MJ
Cochrane Database Syst Rev 2008 Jan 23;(1):CD004517. doi: 10.1002/14651858.CD004517.pub2. PMID: 18254052

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...