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Alcoholic polyneuropathy

MedGen UID:
39087
•Concept ID:
C0085677
•
Disease or Syndrome
Synonyms: Alcohol Induced Peripheral Neuropathy; Alcohol Induced Polyneuropathy; Alcohol Related Autonomic Polyneuropathy; Alcohol Related Polyneuropathy; Alcohol-Induced Peripheral Neuropathies; Alcohol-Induced Peripheral Neuropathy; Alcohol-Induced Polyneuropathies; Alcohol-Induced Polyneuropathy; Alcohol-Related Autonomic Polyneuropathies; Alcohol-Related Autonomic Polyneuropathy; Alcohol-Related Polyneuropathies; Alcohol-Related Polyneuropathy; Alcoholic Neuropathies; Alcoholic Neuropathy; Alcoholic Polyneuritides; Alcoholic Polyneuritis; Alcoholic Polyneuropathies; Alcoholic Polyneuropathy; Autonomic Polyneuropathies, Alcohol-Related; Autonomic Polyneuropathy, Alcohol-Related; Neuropathies, Alcohol-Induced Peripheral; Neuropathies, Alcoholic; Neuropathy, Alcohol-Induced Peripheral; Neuropathy, Alcoholic; Peripheral Neuropathies, Alcohol-Induced; Peripheral Neuropathy, Alcohol Induced; Peripheral Neuropathy, Alcohol-Induced; Polyneuritides, Alcoholic; Polyneuritis, Alcoholic; Polyneuropathies, Alcohol-Induced; Polyneuropathies, Alcohol-Related; Polyneuropathies, Alcohol-Related Autonomic; Polyneuropathies, Alcoholic; Polyneuropathy, Alcohol-Induced; Polyneuropathy, Alcohol-Related; Polyneuropathy, Alcohol-Related Autonomic; Polyneuropathy, Alcoholic
SNOMED CT: Alcoholic peripheral neuropathy (7916009); Alcoholic polyneuropathy (7916009); Alcohol-induced polyneuropathy (7916009)
 
Monarch Initiative: MONDO:0006645

Definition

Any disease affecting more than one nerve. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAlcoholic polyneuropathy

Professional guidelines

PubMed

The role of biofactors in the prevention and treatment of age-related diseases.
Frank J, Kisters K, Stirban OA, Obeid R, Lorkowski S, Wallert M, Egert S, Podszun MC, Eckert GP, Pettersen JA, Venturelli S, Classen HG, Golombek J
Biofactors 2021 Jul;47(4):522-550. Epub 2021 Mar 26 doi: 10.1002/biof.1728. PMID: 33772908
Role of curcumin in the management of pathological pain.
Sun J, Chen F, Braun C, Zhou YQ, Rittner H, Tian YK, Cai XY, Ye DW
Phytomedicine 2018 Sep 15;48:129-140. Epub 2018 Apr 17 doi: 10.1016/j.phymed.2018.04.045. PMID: 30195871
Alcoholic neuropathy: possible mechanisms and future treatment possibilities.
Chopra K, Tiwari V
Br J Clin Pharmacol 2012 Mar;73(3):348-62. doi: 10.1111/j.1365-2125.2011.04111.x. PMID: 21988193Free PMC Article

Recent clinical studies

Etiology

Increased incidence of alcohol use disorder and alcohol-related psychiatric disorders in patients with obstructive sleep apnea: A nationwide population-based cohort study.
Huang YP, Chien WC, Chung CH, Huang YC, Kuo SC, Chen CY, Chen TY, Chang HA, Kao YC, Chang SY, Yeh YW, Tzeng NS
Sleep Med 2023 Jan;101:197-204. Epub 2022 Nov 17 doi: 10.1016/j.sleep.2022.10.031. PMID: 36403533
Clinical Safety and Tolerability of A2NTX, a Novel Low-Molecular-Weight Neurotoxin Derived from Botulinum Neurotoxin Subtype A2, in Comparison with Subtype A1 Toxins.
Takeuchi T, Okuno T, Miyashiro A, Kohda T, Miyamoto R, Izumi Y, Kozaki S, Kaji R
Toxins (Basel) 2021 Nov 22;13(11) doi: 10.3390/toxins13110824. PMID: 34822610Free PMC Article
Alcohol and melatonin.
Kurhaluk N
Chronobiol Int 2021 Jun;38(6):785-800. Epub 2021 Mar 24 doi: 10.1080/07420528.2021.1899198. PMID: 33761823
Treatment of alcoholic polyneuropathy with vitamin B complex: a randomised controlled trial.
Peters TJ, Kotowicz J, Nyka W, Kozubski W, Kuznetsov V, Vanderbist F, de Niet S, Marcereuil D, Coffiner M
Alcohol Alcohol 2006 Nov-Dec;41(6):636-42. Epub 2006 Aug 21 doi: 10.1093/alcalc/agl058. PMID: 16926172
Influence of genetic variations of ethanol-metabolizing enzymes on phenotypes of alcohol-related disorders.
Higuchi S, Matsushita S, Masaki T, Yokoyama A, Kimura M, Suzuki G, Mochizuki H
Ann N Y Acad Sci 2004 Oct;1025:472-80. doi: 10.1196/annals.1316.058. PMID: 15542751

Diagnosis

Increased incidence of alcohol use disorder and alcohol-related psychiatric disorders in patients with obstructive sleep apnea: A nationwide population-based cohort study.
Huang YP, Chien WC, Chung CH, Huang YC, Kuo SC, Chen CY, Chen TY, Chang HA, Kao YC, Chang SY, Yeh YW, Tzeng NS
Sleep Med 2023 Jan;101:197-204. Epub 2022 Nov 17 doi: 10.1016/j.sleep.2022.10.031. PMID: 36403533
Spatial analysis of alcohol-related mortality in Slovakia.
Kubák M, Gavurová B, Kulhánek A
Cent Eur J Public Health 2019 Dec;27 Suppl:S48-S54. doi: 10.21101/cejph.a5766. PMID: 31901192
Strength-duration properties of sensory and motor axons in alcoholic polyneuropathy.
Yerdelen D, Koc F, Uysal H
Neurol Res 2008 Sep;30(7):746-50. Epub 2008 May 16 doi: 10.1179/174313208X291694. PMID: 18489821
Alcoholic polyneuropathy.
Shields RW Jr
Muscle Nerve 1985 Mar-Apr;8(3):183-7. doi: 10.1002/mus.880080302. PMID: 4058462
Alcoholic polyneuropathy.
Juntunen J
Acta Med Scand Suppl 1985;703:265-72. doi: 10.1111/j.0954-6820.1985.tb08922.x. PMID: 3867243

Therapy

Increased incidence of alcohol use disorder and alcohol-related psychiatric disorders in patients with obstructive sleep apnea: A nationwide population-based cohort study.
Huang YP, Chien WC, Chung CH, Huang YC, Kuo SC, Chen CY, Chen TY, Chang HA, Kao YC, Chang SY, Yeh YW, Tzeng NS
Sleep Med 2023 Jan;101:197-204. Epub 2022 Nov 17 doi: 10.1016/j.sleep.2022.10.031. PMID: 36403533
Clinical Safety and Tolerability of A2NTX, a Novel Low-Molecular-Weight Neurotoxin Derived from Botulinum Neurotoxin Subtype A2, in Comparison with Subtype A1 Toxins.
Takeuchi T, Okuno T, Miyashiro A, Kohda T, Miyamoto R, Izumi Y, Kozaki S, Kaji R
Toxins (Basel) 2021 Nov 22;13(11) doi: 10.3390/toxins13110824. PMID: 34822610Free PMC Article
Alcohol and melatonin.
Kurhaluk N
Chronobiol Int 2021 Jun;38(6):785-800. Epub 2021 Mar 24 doi: 10.1080/07420528.2021.1899198. PMID: 33761823
Strength-duration properties of sensory and motor axons in alcoholic polyneuropathy.
Yerdelen D, Koc F, Uysal H
Neurol Res 2008 Sep;30(7):746-50. Epub 2008 May 16 doi: 10.1179/174313208X291694. PMID: 18489821
Benfotiamine in treatment of alcoholic polyneuropathy: an 8-week randomized controlled study (BAP I Study).
Woelk H, Lehrl S, Bitsch R, Köpcke W
Alcohol Alcohol 1998 Nov-Dec;33(6):631-8. doi: 10.1093/alcalc/33.6.631. PMID: 9872352

Prognosis

Increased incidence of alcohol use disorder and alcohol-related psychiatric disorders in patients with obstructive sleep apnea: A nationwide population-based cohort study.
Huang YP, Chien WC, Chung CH, Huang YC, Kuo SC, Chen CY, Chen TY, Chang HA, Kao YC, Chang SY, Yeh YW, Tzeng NS
Sleep Med 2023 Jan;101:197-204. Epub 2022 Nov 17 doi: 10.1016/j.sleep.2022.10.031. PMID: 36403533
Spatial analysis of alcohol-related mortality in Slovakia.
Kubák M, Gavurová B, Kulhánek A
Cent Eur J Public Health 2019 Dec;27 Suppl:S48-S54. doi: 10.21101/cejph.a5766. PMID: 31901192
Benfotiamine in treatment of alcoholic polyneuropathy: an 8-week randomized controlled study (BAP I Study).
Woelk H, Lehrl S, Bitsch R, Köpcke W
Alcohol Alcohol 1998 Nov-Dec;33(6):631-8. doi: 10.1093/alcalc/33.6.631. PMID: 9872352
Drinking habits and peripheral alcoholic neuropathy.
Kemppainen R, Juntunen J, Hillbom M
Acta Neurol Scand 1982 Jan;65(1):11-8. doi: 10.1111/j.1600-0404.1982.tb03056.x. PMID: 6278809
Evidence of vagal neuropathy in chronic alcoholics.
Duncan G, Johnson RH, Lambie DG, Whiteside EA
Lancet 1980 Nov 15;2(8203):1053-7. doi: 10.1016/s0140-6736(80)92275-8. PMID: 6107680

Clinical prediction guides

Benfotiamine in treatment of alcoholic polyneuropathy: an 8-week randomized controlled study (BAP I Study).
Woelk H, Lehrl S, Bitsch R, Köpcke W
Alcohol Alcohol 1998 Nov-Dec;33(6):631-8. doi: 10.1093/alcalc/33.6.631. PMID: 9872352
Remission of severe alcoholic polyneuropathy after liver transplantation.
Spahn TW, Lohse AW, Otto G, Tettenborn B, Hopf HC, Meyer zum Büschenfelde KH
Z Gastroenterol 1995 Dec;33(12):711-4. PMID: 8585254
Is heat hypoalgesia a useful parameter in quantitative thermal testing of alcoholic polyneuropathy?
Hilz MJ, Claus D, Neundörfer B, Zimmermann P, Berić A
Muscle Nerve 1994 Dec;17(12):1456-60. doi: 10.1002/mus.880171215. PMID: 7969246
Bulbocavernosus reflex in normal men and in patients with neurogenic bladder and/or impotence.
Ertekin C, Reel F
J Neurol Sci 1976 May;28(1):1-15. doi: 10.1016/0022-510x(76)90044-7. PMID: 180261

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