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Lentivirus infection

MedGen UID:
38233
•Concept ID:
C0079680
•
Disease or Syndrome
Synonyms: Infection, Lentivirus; Infections, Lentivirus; Lentivirus Infection; Lentivirus Infections
SNOMED CT: Disease caused by Lentivirus (24907000)
 
Monarch Initiative: MONDO:0022034

Definition

Virus diseases caused by the Lentivirus genus. They are multi-organ diseases characterized by long incubation periods and persistent infection. [from MONDO]

Professional guidelines

PubMed

CD24 is a novel target of chimeric antigen receptor T cells for the treatment of triple negative breast cancer.
Yang P, Yu F, Yao Z, Ding X, Xu H, Zhang J
Cancer Immunol Immunother 2023 Oct;72(10):3191-3202. Epub 2023 Jul 7 doi: 10.1007/s00262-023-03491-7. PMID: 37418008Free PMC Article
Evaluating adipose-derived stem cell exosomes as miRNA drug delivery systems for the treatment of bladder cancer.
Liu T, Li T, Zheng Y, Xu X, Sun R, Zhan S, Guo X, Zhao Z, Zhu W, Feng B, Wei F, Jiang N, Wang J, Chen X, Fang F, Guo H, Yang R
Cancer Med 2022 Oct;11(19):3687-3699. Epub 2022 Apr 20 doi: 10.1002/cam4.4745. PMID: 35441482Free PMC Article
The in vitro and in vivo treatment effects of overexpressed lentiviral vector-mediated human BMP2 gene in the femoral bone marrow stromal cells of osteoporotic rats.
Zhao B, Wang Q, Tao T, Li J, Lin Q
Int J Mol Med 2013 Dec;32(6):1355-65. Epub 2013 Sep 25 doi: 10.3892/ijmm.2013.1507. PMID: 24068163

Recent clinical studies

Etiology

CBX4 suppresses CD8(+) T cell antitumor immunity by reprogramming glycolytic metabolism.
Wang J, Jia W, Zhou X, Ma Z, Liu J, Lan P
Theranostics 2024;14(10):3793-3809. Epub 2024 Jun 17 doi: 10.7150/thno.95748. PMID: 38994031Free PMC Article
ErbB4 affects Th1/Th17 cell differentiation and promotes psoriasis progression.
Tang R, Cui H, Dou R, Tao L, Tan L, Guo T, Luo D
Cell Mol Biol (Noisy-le-grand) 2023 Nov 30;69(12):1-5. doi: 10.14715/cmb/2023.69.12.1. PMID: 38063127
KIF2C promotes clear cell renal cell carcinoma progression via activating JAK2/STAT3 signaling pathway.
Deng H, Gong X, Ji G, Li C, Cheng S
Mol Cell Probes 2023 Dec;72:101938. Epub 2023 Oct 28 doi: 10.1016/j.mcp.2023.101938. PMID: 37863123
Antioxioxidant and antiapoptotic effects of Thymosin β4 in Aβ-induced SH-SY5Y cells via the 5-HTR1A/ERK axis.
Zhang GH, Chin KL, Yan SY, Pare R
PLoS One 2023;18(10):e0287817. Epub 2023 Oct 3 doi: 10.1371/journal.pone.0287817. PMID: 37788276Free PMC Article
Safety considerations in vector development.
Kappes JC, Wu X
Somat Cell Mol Genet 2001 Nov;26(1-6):147-58. doi: 10.1023/a:1021082815013. PMID: 12465466

Diagnosis

Sympathetic β(2)-adrenergic receptor blockade overcomes docetaxel resistance in prostate cancer.
Zhang M, Chen F, Sun X, Huang Y, Zeng Y, Chen J, Wu S, Xu C
Biochem Biophys Res Commun 2023 May 21;657:69-79. Epub 2023 Mar 21 doi: 10.1016/j.bbrc.2023.03.046. PMID: 36989842
LHPP inhibits hepatocellular carcinoma cell growth and metastasis.
Liao L, Duan D, Liu Y, Chen L
Cell Cycle 2020 Jul;19(14):1846-1854. Epub 2020 Jun 24 doi: 10.1080/15384101.2020.1783472. PMID: 32578511Free PMC Article
MiR-873/PD-L1 axis regulates the stemness of breast cancer cells.
Gao L, Guo Q, Li X, Yang X, Ni H, Wang T, Zhao Q, Liu H, Xing Y, Xi T, Zheng L
EBioMedicine 2019 Mar;41:395-407. Epub 2019 Feb 23 doi: 10.1016/j.ebiom.2019.02.034. PMID: 30803931Free PMC Article
HSP90AA1-mediated autophagy promotes drug resistance in osteosarcoma.
Xiao X, Wang W, Li Y, Yang D, Li X, Shen C, Liu Y, Ke X, Guo S, Guo Z
J Exp Clin Cancer Res 2018 Aug 28;37(1):201. doi: 10.1186/s13046-018-0880-6. PMID: 30153855Free PMC Article
Safety considerations in vector development.
Kappes JC, Wu X
Somat Cell Mol Genet 2001 Nov;26(1-6):147-58. doi: 10.1023/a:1021082815013. PMID: 12465466

Therapy

Sympathetic β(2)-adrenergic receptor blockade overcomes docetaxel resistance in prostate cancer.
Zhang M, Chen F, Sun X, Huang Y, Zeng Y, Chen J, Wu S, Xu C
Biochem Biophys Res Commun 2023 May 21;657:69-79. Epub 2023 Mar 21 doi: 10.1016/j.bbrc.2023.03.046. PMID: 36989842
S6K1 amplification confers innate resistance to CDK4/6 inhibitors through activating c-Myc pathway in patients with estrogen receptor-positive breast cancer.
Mo H, Liu X, Xue Y, Chen H, Guo S, Li Z, Wang S, Li C, Han J, Fu M, Song Y, Li D, Ma F
Mol Cancer 2022 Aug 30;21(1):171. doi: 10.1186/s12943-022-01642-5. PMID: 36042494Free PMC Article
MiR-873/PD-L1 axis regulates the stemness of breast cancer cells.
Gao L, Guo Q, Li X, Yang X, Ni H, Wang T, Zhao Q, Liu H, Xing Y, Xi T, Zheng L
EBioMedicine 2019 Mar;41:395-407. Epub 2019 Feb 23 doi: 10.1016/j.ebiom.2019.02.034. PMID: 30803931Free PMC Article
HSP90AA1-mediated autophagy promotes drug resistance in osteosarcoma.
Xiao X, Wang W, Li Y, Yang D, Li X, Shen C, Liu Y, Ke X, Guo S, Guo Z
J Exp Clin Cancer Res 2018 Aug 28;37(1):201. doi: 10.1186/s13046-018-0880-6. PMID: 30153855Free PMC Article
The FcγR of humans and non-human primates and their interaction with IgG: implications for induction of inflammation, resistance to infection and the use of therapeutic monoclonal antibodies.
Hogarth PM, Anania JC, Wines BD
Curr Top Microbiol Immunol 2014;382:321-52. doi: 10.1007/978-3-319-07911-0_15. PMID: 25116107

Prognosis

ZNF554 Inhibits Endometrial Cancer Progression via Regulating RBM5 and Inactivating WNT/β-Catenin Signaling Pathway.
Zhu CC, Sun HL, Long TF, Lyu YY, Liu JL, Ni GT
Curr Med Sci 2024 Apr;44(2):406-418. Epub 2024 Apr 15 doi: 10.1007/s11596-024-2845-7. PMID: 38619681
ErbB4 affects Th1/Th17 cell differentiation and promotes psoriasis progression.
Tang R, Cui H, Dou R, Tao L, Tan L, Guo T, Luo D
Cell Mol Biol (Noisy-le-grand) 2023 Nov 30;69(12):1-5. doi: 10.14715/cmb/2023.69.12.1. PMID: 38063127
KIF2C promotes clear cell renal cell carcinoma progression via activating JAK2/STAT3 signaling pathway.
Deng H, Gong X, Ji G, Li C, Cheng S
Mol Cell Probes 2023 Dec;72:101938. Epub 2023 Oct 28 doi: 10.1016/j.mcp.2023.101938. PMID: 37863123
S6K1 amplification confers innate resistance to CDK4/6 inhibitors through activating c-Myc pathway in patients with estrogen receptor-positive breast cancer.
Mo H, Liu X, Xue Y, Chen H, Guo S, Li Z, Wang S, Li C, Han J, Fu M, Song Y, Li D, Ma F
Mol Cancer 2022 Aug 30;21(1):171. doi: 10.1186/s12943-022-01642-5. PMID: 36042494Free PMC Article
Safety considerations in vector development.
Kappes JC, Wu X
Somat Cell Mol Genet 2001 Nov;26(1-6):147-58. doi: 10.1023/a:1021082815013. PMID: 12465466

Clinical prediction guides

ErbB4 affects Th1/Th17 cell differentiation and promotes psoriasis progression.
Tang R, Cui H, Dou R, Tao L, Tan L, Guo T, Luo D
Cell Mol Biol (Noisy-le-grand) 2023 Nov 30;69(12):1-5. doi: 10.14715/cmb/2023.69.12.1. PMID: 38063127
S6K1 amplification confers innate resistance to CDK4/6 inhibitors through activating c-Myc pathway in patients with estrogen receptor-positive breast cancer.
Mo H, Liu X, Xue Y, Chen H, Guo S, Li Z, Wang S, Li C, Han J, Fu M, Song Y, Li D, Ma F
Mol Cancer 2022 Aug 30;21(1):171. doi: 10.1186/s12943-022-01642-5. PMID: 36042494Free PMC Article
A novel miRNA-762/NFIX pathway modulates LPS-induced acute lung injury.
Zhang XL, An J, Deng YZ, Fang XZ, Xu CY, Liu XF, Bai ZH, Zhang G, Cui MY
Int Immunopharmacol 2021 Nov;100:108066. Epub 2021 Sep 4 doi: 10.1016/j.intimp.2021.108066. PMID: 34492536
HASPIN is involved in the progression of gallbladder carcinoma.
Zhu D, Gu X, Lin Z, Yu D, Wang J, Li L
Exp Cell Res 2020 May 15;390(2):111863. Epub 2020 Jan 25 doi: 10.1016/j.yexcr.2020.111863. PMID: 31987787
Safety considerations in vector development.
Kappes JC, Wu X
Somat Cell Mol Genet 2001 Nov;26(1-6):147-58. doi: 10.1023/a:1021082815013. PMID: 12465466

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