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Urethritis

MedGen UID:
52934
•Concept ID:
C0041976
•
Disease or Syndrome
Synonym: Urethritides
SNOMED CT: Inflammation of urethra (31822004); Urethritis (31822004)
 
HPO: HP:0500006
Monarch Initiative: MONDO:0005297

Definition

Inflammation of the urethra. [from HPO]

Professional guidelines

PubMed

Epidemiology, Natural History, Diagnosis, and Treatment of Trichomonas vaginalis in Men.
Van Gerwen OT, Camino AF, Sharma J, Kissinger PJ, Muzny CA
Clin Infect Dis 2021 Sep 15;73(6):1119-1124. doi: 10.1093/cid/ciab514. PMID: 34079999Free PMC Article
Sexually transmitted diseases treatment guidelines, 2015.
Workowski KA, Bolan GA; Centers for Disease Control and Prevention
MMWR Recomm Rep 2015 Jun 5;64(RR-03):1-137. PMID: 26042815Free PMC Article
Urinary retention in adults: diagnosis and initial management.
Selius BA, Subedi R
Am Fam Physician 2008 Mar 1;77(5):643-50. PMID: 18350762

Recent clinical studies

Etiology

Meningococcal Urethritis: Old and New.
Burns BL, Rhoads DD
J Clin Microbiol 2022 Nov 16;60(11):e0057522. Epub 2022 Aug 15 doi: 10.1128/jcm.00575-22. PMID: 35969045Free PMC Article
Idiopathic hemorrhagic urethritis of childhood.
Eyer de Jesus L, Fazecas T, Anderson KM, Dekermacher S
J Pediatr Urol 2020 Oct;16(5):690-699. Epub 2020 Jul 22 doi: 10.1016/j.jpurol.2020.07.021. PMID: 32762951
Mycoplasma genitalium Infection in Men.
Horner PJ, Martin DH
J Infect Dis 2017 Jul 15;216(suppl_2):S396-S405. doi: 10.1093/infdis/jix145. PMID: 28838074Free PMC Article
Epididymitis.
Taylor SN
Clin Infect Dis 2015 Dec 15;61 Suppl 8:S770-3. doi: 10.1093/cid/civ812. PMID: 26602616
Mycoplasma genitalium: a review.
Daley GM, Russell DB, Tabrizi SN, McBride J
Int J STD AIDS 2014 Jun;25(7):475-87. Epub 2014 Feb 11 doi: 10.1177/0956462413515196. PMID: 24517928

Diagnosis

Nongonococcal tysonitis.
Vallejo-Ruiz MS, Sandoval-Garcés M, Bru-Gorraiz FJ, Martín-Gorgojo A
Int J STD AIDS 2024 Feb;35(2):155-157. Epub 2023 Oct 18 doi: 10.1177/09564624231208241. PMID: 37852285
Meningococcal Urethritis: Old and New.
Burns BL, Rhoads DD
J Clin Microbiol 2022 Nov 16;60(11):e0057522. Epub 2022 Aug 15 doi: 10.1128/jcm.00575-22. PMID: 35969045Free PMC Article
Urethritis.
Am Fam Physician 2021 May 1;103(9):Online. PMID: 33929176
Urethritis: Rapid Evidence Review.
Sell J, Nasir M, Courchesne C
Am Fam Physician 2021 May 1;103(9):553-558. PMID: 33929174
Epididymitis.
Taylor SN
Clin Infect Dis 2015 Dec 15;61 Suppl 8:S770-3. doi: 10.1093/cid/civ812. PMID: 26602616

Therapy

Urethritis.
Am Fam Physician 2021 May 1;103(9):Online. PMID: 33929176
Mycoplasma genitalium Infection in Men.
Horner PJ, Martin DH
J Infect Dis 2017 Jul 15;216(suppl_2):S396-S405. doi: 10.1093/infdis/jix145. PMID: 28838074Free PMC Article
Grepafloxacin.
Wagstaff AJ, Balfour JA
Drugs 1997 May;53(5):817-24; discussion 825-7. doi: 10.2165/00003495-199753050-00007. PMID: 9129868
Azithromycin in gonorrhoea.
Waugh MA
Int J STD AIDS 1996;7 Suppl 1:2-4. doi: 10.1258/0956462961917212. PMID: 8652723
Nongonococcal urethritis.
Kogan BA
Urology 1981 Mar;17(3):219-22. doi: 10.1016/0090-4295(81)90032-7. PMID: 6782735

Prognosis

2021 European guideline on the management of Mycoplasma genitalium infections.
Jensen JS, Cusini M, Gomberg M, Moi H, Wilson J, Unemo M
J Eur Acad Dermatol Venereol 2022 May;36(5):641-650. Epub 2022 Feb 19 doi: 10.1111/jdv.17972. PMID: 35182080
Reactive arthritis: a clinical review.
Jubber A, Moorthy A
J R Coll Physicians Edinb 2021 Sep;51(3):288-297. doi: 10.4997/JRCPE.2021.319. PMID: 34528623
Idiopathic hemorrhagic urethritis of childhood.
Eyer de Jesus L, Fazecas T, Anderson KM, Dekermacher S
J Pediatr Urol 2020 Oct;16(5):690-699. Epub 2020 Jul 22 doi: 10.1016/j.jpurol.2020.07.021. PMID: 32762951
Reactive arthritis.
Kwiatkowska B, Filipowicz-Sosnowska A
Pol Arch Med Wewn 2009 Jan-Feb;119(1-2):60-5. PMID: 19341180
Gynecological chlamydial infections.
Weström L
Infection 1982;10 Suppl 1:S40-5. doi: 10.1007/BF01640713. PMID: 7044982

Clinical prediction guides

Clinical performance of four multiplex real-time PCR kits detecting urogenital and sexually transmitted pathogens.
Pereyre S, Caméléna F, Hénin N, Berçot B, Bébéar C
Clin Microbiol Infect 2022 May;28(5):733.e7-733.e13. Epub 2021 Oct 2 doi: 10.1016/j.cmi.2021.09.028. PMID: 34610459
Reactive arthritis: images.
Aitken-Saavedra J, Maturana-Ramirez A, Fernández Moraga J, Doro Dias V, Galdino-Santos L, Pineda Flores D
Dermatol Online J 2021 Jul 15;27(7) doi: 10.5070/D327754373. PMID: 34391335
Clinical profile and co-infections of urethritis in males.
Bellinato F, Maurelli M, Gisondi P, Lleo Fernandez M, Girolomoni G
Ital J Dermatol Venerol 2021 Dec;156(6):681-685. Epub 2021 Jan 11 doi: 10.23736/S2784-8671.20.06773-5. PMID: 33423450
Mycoplasma genitalium: Accurate Diagnosis Is Necessary for Adequate Treatment.
Gaydos CA
J Infect Dis 2017 Jul 15;216(suppl_2):S406-S411. doi: 10.1093/infdis/jix104. PMID: 28838072Free PMC Article
Mycoplasma genitalium: a review.
Daley GM, Russell DB, Tabrizi SN, McBride J
Int J STD AIDS 2014 Jun;25(7):475-87. Epub 2014 Feb 11 doi: 10.1177/0956462413515196. PMID: 24517928

Recent systematic reviews

Treatment of Mycoplasma genitalium infection in pregnancy: A systematic review of international guidelines.
Drew RJ, Eogan M
Int J Gynaecol Obstet 2024 Jul;166(1):27-34. Epub 2024 Mar 15 doi: 10.1002/ijgo.15469. PMID: 38491782
Association of mycoplasma with prostate cancer: A systematic review and meta-analysis.
Tantengco OAG, Aquino IMC, de Castro Silva M, Rojo RD, Abad CLR
Cancer Epidemiol 2021 Dec;75:102021. Epub 2021 Sep 10 doi: 10.1016/j.canep.2021.102021. PMID: 34517226
Prevalence of Mycoplasma genitalium in different population groups: systematic review andmeta-analysis.
Baumann L, Cina M, Egli-Gany D, Goutaki M, Halbeisen FS, Lohrer GR, Ali H, Scott P, Low N
Sex Transm Infect 2018 Jun;94(4):255-262. Epub 2018 Feb 9 doi: 10.1136/sextrans-2017-053384. PMID: 29440466Free PMC Article
Human parasitic protozoan infection to infertility: a systematic review.
Shiadeh MN, Niyyati M, Fallahi S, Rostami A
Parasitol Res 2016 Feb;115(2):469-77. Epub 2015 Nov 16 doi: 10.1007/s00436-015-4827-y. PMID: 26573517
Are Ureaplasma spp. a cause of nongonococcal urethritis? A systematic review and meta-analysis.
Zhang N, Wang R, Li X, Liu X, Tang Z, Liu Y
PLoS One 2014;9(12):e113771. Epub 2014 Dec 2 doi: 10.1371/journal.pone.0113771. PMID: 25463970Free PMC Article

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