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Epidemic louse-borne typhus

MedGen UID:
21744
Concept ID:
C0041473
Disease or Syndrome
Synonyms: Epidemic Louse-Borne Typhus; Epidemic Typhus; Fever, Jail; Infection, Rickettsia prowazekii; Jail Fever; Louse Borne Typhus; Louse-Borne Typhus; Louse-Borne Typhus, Epidemic; Rickettsia prowazekii Infection; Rickettsia prowazekii Infections; Typhus, Epidemic; Typhus, Epidemic Louse Borne; Typhus, Epidemic Louse-Borne; Typhus, Louse-Borne
SNOMED CT: Louse-borne epidemic typhus (39111003); European typhus (39111003); Tabardillo (39111003); Fleckfieber (39111003); Louse-borne typhus fever (39111003); Tifus exanthematico (39111003); Louse-borne typhus (39111003); Epidemic typhus (39111003); Classical typhus (39111003); Typhus due to Rickettsia prowazekii (39111003); Exanthematic typhus (39111003)
Modes of inheritance:
Not genetically inherited
MedGen UID:
988794
Concept ID:
CN307044
Finding
Source: Orphanet
clinical entity without genetic inheritance.
 
Monarch Initiative: MONDO:0019362
Orphanet: ORPHA83314

Definition

A Rickettsial disease characterized by malaise and vague symptoms before the onset of high fever, headache, severe myalgias and less commonly petechial rash on the trunk and limbs, nausea, vomiting, coughing and pneumonia. Most patients also have some central nervous system disturbances, such as meningeal irritation, confusion, drowsiness, seizures, coma, and hearing loss. [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEpidemic louse-borne typhus
Follow this link to review classifications for Epidemic louse-borne typhus in Orphanet.

Professional guidelines

PubMed

Chan C, Demetriades AK
J Med Biogr 2023 Feb;31(1):4-9. Epub 2021 Feb 27 doi: 10.1177/0967772021994560. PMID: 33641510Free PMC Article
Botelho-Nevers E, Socolovschi C, Raoult D, Parola P
Expert Rev Anti Infect Ther 2012 Dec;10(12):1425-37. doi: 10.1586/eri.12.139. PMID: 23253320
Perine PL, Krause DW, Awoke S, McDade JE
Lancet 1974 Sep 28;2(7883):742-4. doi: 10.1016/s0140-6736(74)90940-4. PMID: 4143011

Recent clinical studies

Etiology

Polak A, Pawlikowska-Łagód K, Zagaja A, Grzybowski A
Clin Dermatol 2023 Nov-Dec;41(6):767-771. Epub 2023 Sep 21 doi: 10.1016/j.clindermatol.2023.09.009. PMID: 37741590
Ouarti B, Mbogning Fonkou DM, Houhamdi L, Mediannikov O, Parola P
Acta Trop 2023 Jan;237:106709. Epub 2022 Oct 2 doi: 10.1016/j.actatropica.2022.106709. PMID: 36198330
Buchanan R
Br J Hosp Med (Lond) 2018 Oct 2;79(10):C146-C149. doi: 10.12968/hmed.2018.79.10.C146. PMID: 30290740
Burns JN, Acuna-Soto R, Stahle DW
Emerg Infect Dis 2014 Mar;20(3):442-7. doi: 10.3201/eid2003.131366. PMID: 24564928Free PMC Article
Badiaga S, Brouqui P
Clin Microbiol Infect 2012 Apr;18(4):332-7. Epub 2012 Feb 23 doi: 10.1111/j.1469-0691.2012.03778.x. PMID: 22360386

Diagnosis

Buchanan R
Br J Hosp Med (Lond) 2018 Oct 2;79(10):C146-C149. doi: 10.12968/hmed.2018.79.10.C146. PMID: 30290740
Angelakis E, Bechah Y, Raoult D
Microbiol Spectr 2016 Aug;4(4) doi: 10.1128/microbiolspec.PoH-0010-2015. PMID: 27726780
Dalton J, Shaw R, Democratis J
Lancet 2014 Mar 22;383(9922):1098. doi: 10.1016/S0140-6736(14)60262-2. PMID: 24656202
Littman RJ
Mt Sinai J Med 2009 Oct;76(5):456-67. doi: 10.1002/msj.20137. PMID: 19787658
Bechah Y, Capo C, Mege JL, Raoult D
Lancet Infect Dis 2008 Jul;8(7):417-26. doi: 10.1016/S1473-3099(08)70150-6. PMID: 18582834

Therapy

Olivo-Freites C, Davar K, Gallardo-Huizar O, Vijayan T, Younes R
Am J Trop Med Hyg 2024 Jan 3;110(1):150-154. Epub 2023 Dec 4 doi: 10.4269/ajtmh.22-0794. PMID: 38052087Free PMC Article
Alarcón J, Sanosyan A, Contreras ZA, Ngo VP, Carpenter A, Hacker JK, Probert WS, Terashita D, Balter S, Halai UA
MMWR Morb Mortal Wkly Rep 2023 Aug 4;72(31):838-843. doi: 10.15585/mmwr.mm7231a1. PMID: 37535465Free PMC Article
Warrell CE, Osborne J, Nabarro L, Gibney B, Carter DP, Warner J, Houlihan CF, Brooks TJG, Rampling T
J Infect 2023 May;86(5):446-452. Epub 2023 Mar 21 doi: 10.1016/j.jinf.2023.03.015. PMID: 36948252
Azizi MH, Bahadori M, Azizi F
Arch Iran Med 2016 Oct;19(10):747-750. PMID: 27743443
Botelho-Nevers E, Socolovschi C, Raoult D, Parola P
Expert Rev Anti Infect Ther 2012 Dec;10(12):1425-37. doi: 10.1586/eri.12.139. PMID: 23253320

Prognosis

Han L, Zhang Y, Jin X, Ren H, Teng Z, Sun Z, Xu J, Qin T
Int J Infect Dis 2024 Mar;140:52-61. Epub 2023 Dec 30 doi: 10.1016/j.ijid.2023.12.013. PMID: 38163619
Yomogida K, Kjemtrup A, Martínez-López B, Ibrahim M, Contreras Z, Ngo V, Halai UA, Balter S, Feaster M, Zahn M, Shearer E, Sorvillo R, Balanji N, Torres C, Prado B, Porse C, Kramer V
Am J Trop Med Hyg 2024 Jan 3;110(1):142-149. Epub 2023 Dec 18 doi: 10.4269/ajtmh.23-0272. PMID: 38109767Free PMC Article
Alarcón J, Sanosyan A, Contreras ZA, Ngo VP, Carpenter A, Hacker JK, Probert WS, Terashita D, Balter S, Halai UA
MMWR Morb Mortal Wkly Rep 2023 Aug 4;72(31):838-843. doi: 10.15585/mmwr.mm7231a1. PMID: 37535465Free PMC Article
Golshani SA, Mansourbakht G, Alembizar F
Arch Iran Med 2022 Nov 1;25(11):758-764. doi: 10.34172/aim.2022.120. PMID: 37543902Free PMC Article
Littman RJ
Mt Sinai J Med 2009 Oct;76(5):456-67. doi: 10.1002/msj.20137. PMID: 19787658

Clinical prediction guides

Dzul-Rosado K, Panti-Balam C, Lavín-Sánchez D, Palma-Chan A, Caamal-Poot M, Achach-Medina K, Quiñones-Vega C, Lugo-Caballero C, Noh-Pech H, Tello-Martín R, López-Ávila K, Arias-León J, González-Reynoso A, Puerto-Manzano F
Acta Trop 2024 Jan;249:107048. Epub 2023 Nov 4 doi: 10.1016/j.actatropica.2023.107048. PMID: 37931342
Song WY, Lv Y, Yin PW, Yang YY, Guo XG
Parasit Vectors 2023 May 16;16(1):164. doi: 10.1186/s13071-023-05789-y. PMID: 37194039Free PMC Article
Hotez PJ, Booker C
PLoS Negl Trop Dis 2020 Feb;14(2):e0008064. Epub 2020 Feb 27 doi: 10.1371/journal.pntd.0008064. PMID: 32106246Free PMC Article
Trung NV, Hoi LT, Thuong NTH, Toan TK, Huong TTK, Hoa TM, Fox A, Kinh NV, van Doorn HR, Wertheim HFL, Bryant JE, Nadjm B
Am J Trop Med Hyg 2017 May;96(5):1084-1087. doi: 10.4269/ajtmh.16-0399. PMID: 28500808Free PMC Article
Gillespie JJ, Beier MS, Rahman MS, Ammerman NC, Shallom JM, Purkayastha A, Sobral BS, Azad AF
PLoS One 2007 Mar 7;2(3):e266. doi: 10.1371/journal.pone.0000266. PMID: 17342200Free PMC Article

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