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Infection by larvae of Trichinella

MedGen UID:
21645
Concept ID:
C0040896
Disease or Syndrome
Synonyms: Human trichinellosis; Infection with trichinella; Trichinellosis; Trichiniasis; Trichinosis
SNOMED CT: Trichinellosis (709018004); Infection by larvae of Trichinella (709018004); Trichiniasis (709018004); Trichinosis (709018004); Trichinelliasis (709018004); Infection caused by larvae of Trichinella (709018004)
Modes of inheritance:
Not genetically inherited
MedGen UID:
988794
Concept ID:
CN307044
Finding
Source: Orphanet
clinical entity without genetic inheritance.
 
Monarch Initiative: MONDO:0019444
Orphanet: ORPHA863

Definition

Trichinellosis is a zoonotic parasitic disease caused by the consumption of raw or undercooked meat (pork and wild game) infected by nematodes of the genus <i>Trichinella</i> and that is characterized by an enteral (intestinal) phase, that can be asymptomatic or that can manifests with diarrhea, nausea, vomiting and abdominal pain, and a parenteral (muscular) phase, manifesting with fever, periorbital edema, muscle swelling and pain, weakness, and in some cases, skin rash and peripheral edema. Rarely, potentially fatal cardiac (i.e. myocarditis), pulmonary (i.e. pneumonitis, respiratory failure), and nervous system (i.e. meningoencephalitis) complications may occur. [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVInfection by larvae of Trichinella
Follow this link to review classifications for Infection by larvae of Trichinella in Orphanet.

Professional guidelines

PubMed

Zarlenga D, Thompson P, Pozio E
Res Vet Sci 2020 Dec;133:289-296. Epub 2020 Sep 1 doi: 10.1016/j.rvsc.2020.08.012. PMID: 33199264
Shimoni Z, Froom P
Expert Rev Anti Infect Ther 2015;13(10):1279-88. Epub 2015 Aug 4 doi: 10.1586/14787210.2015.1075394. PMID: 26243167
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Recent clinical studies

Etiology

Eslahi AV, KarimiPourSaryazdi A, Olfatifar M, de Carvalho LMM, Foroutan M, Karim MR, Badri M, Ketzis JK
Vet Med Sci 2022 Nov;8(6):2466-2481. Epub 2022 Sep 22 doi: 10.1002/vms3.951. PMID: 36137293Free PMC Article
Alban L, Häsler B, van Schaik G, Ruegg S
Exp Parasitol 2020 Jan;208:107808. Epub 2019 Nov 22 doi: 10.1016/j.exppara.2019.107808. PMID: 31765613
Rostami A, Gamble HR, Dupouy-Camet J, Khazan H, Bruschi F
Food Microbiol 2017 Jun;64:65-71. Epub 2016 Dec 22 doi: 10.1016/j.fm.2016.12.012. PMID: 28213036
Johnston CJ, McSorley HJ, Anderton SM, Wigmore SJ, Maizels RM
Transplantation 2014 Jan 27;97(2):127-32. doi: 10.1097/TP.0b013e3182a53f59. PMID: 24025322Free PMC Article
Pozio E, Darwin Murrell K
Adv Parasitol 2006;63:367-439. doi: 10.1016/S0065-308X(06)63005-4. PMID: 17134656

Diagnosis

Pyzocha N, Cuda A
Am Fam Physician 2023 Nov;108(5):487-493. PMID: 37983700
Zarlenga D, Thompson P, Pozio E
Res Vet Sci 2020 Dec;133:289-296. Epub 2020 Sep 1 doi: 10.1016/j.rvsc.2020.08.012. PMID: 33199264
Van De N, Thi Nga V, Dorny P, Vu Trung N, Ngoc Minh P, Trung Dung D, Pozio E
Am J Trop Med Hyg 2015 Jun;92(6):1265-70. Epub 2015 Apr 6 doi: 10.4269/ajtmh.14-0570. PMID: 25846295Free PMC Article
Schmutzhard E, Helbok R
Handb Clin Neurol 2014;121:1403-43. doi: 10.1016/B978-0-7020-4088-7.00096-1. PMID: 24365428
Bruschi F, Brunetti E, Pozio E
Handb Clin Neurol 2013;114:243-9. doi: 10.1016/B978-0-444-53490-3.00019-4. PMID: 23829915

Therapy

Pyzocha N, Cuda A
Am Fam Physician 2023 Nov;108(5):487-493. PMID: 37983700
Shimoni Z, Froom P
Expert Rev Anti Infect Ther 2015;13(10):1279-88. Epub 2015 Aug 4 doi: 10.1586/14787210.2015.1075394. PMID: 26243167
Katz M
Drugs 1977 Feb;13(2):124-36. doi: 10.2165/00003495-197713020-00002. PMID: 319991
Br Med J 1970 Mar 14;1(5697):676-7. PMID: 5443972Free PMC Article
Thomas PK
Br Med J 1970 Feb 14;1(5693):413-5. doi: 10.1136/bmj.1.5693.413. PMID: 5265023Free PMC Article

Prognosis

Uthailak N, Adisakwattana P, Chienwichai P, Tipthara P, Tarning J, Thawornkuno C, Thiangtrongjit T, Reamtong O
Front Cell Infect Microbiol 2023;13:1306567. Epub 2023 Dec 8 doi: 10.3389/fcimb.2023.1306567. PMID: 38145042Free PMC Article
Fredriksson-Ahomaa M
Foodborne Pathog Dis 2019 Mar;16(3):153-165. Epub 2018 Nov 27 doi: 10.1089/fpd.2018.2512. PMID: 30481068
Nunes MC, Guimarães Júnior MH, Diamantino AC, Gelape CL, Ferrari TC
Heart 2017 May;103(9):651-658. Epub 2017 Mar 11 doi: 10.1136/heartjnl-2016-309870. PMID: 28285268
Sofronic-Milosavljevic L, Ilic N, Pinelli E, Gruden-Movsesijan A
J Immunol Res 2015;2015:523875. Epub 2015 May 31 doi: 10.1155/2015/523875. PMID: 26114122Free PMC Article
Hotez PJ, Gurwith M
Int J Infect Dis 2011 Sep;15(9):e611-9. Epub 2011 Jul 16 doi: 10.1016/j.ijid.2011.05.006. PMID: 21763173

Clinical prediction guides

Chu KB, Lee HA, Kang HJ, Moon EK, Quan FS
Cells 2020 May 25;9(5) doi: 10.3390/cells9051314. PMID: 32466130Free PMC Article
Pavic S, Andric A, Sofronic-Milosavljevic LJ, Gnjatovic M, Mitić I, Vasilev S, Sparic R, Pavic A
Med Mal Infect 2020 Sep;50(6):520-524. Epub 2019 Nov 12 doi: 10.1016/j.medmal.2019.10.008. PMID: 31732242
Nunes MC, Guimarães Júnior MH, Diamantino AC, Gelape CL, Ferrari TC
Heart 2017 May;103(9):651-658. Epub 2017 Mar 11 doi: 10.1136/heartjnl-2016-309870. PMID: 28285268
Saracino MP, Calcagno MA, Beauche EB, Garnier A, Vila CC, Granchetti H, Taus MR, Venturiello SM
Vet Parasitol 2016 Nov 15;231:2-7. Epub 2016 Jun 24 doi: 10.1016/j.vetpar.2016.06.019. PMID: 27349972
Mukaratirwa S, La Grange L, Pfukenyi DM
Acta Trop 2013 Jan;125(1):82-9. Epub 2012 Oct 5 doi: 10.1016/j.actatropica.2012.09.005. PMID: 23041114

Recent systematic reviews

Eslahi AV, KarimiPourSaryazdi A, Olfatifar M, de Carvalho LMM, Foroutan M, Karim MR, Badri M, Ketzis JK
Vet Med Sci 2022 Nov;8(6):2466-2481. Epub 2022 Sep 22 doi: 10.1002/vms3.951. PMID: 36137293Free PMC Article
Moazeni M, Khamesipour F, Anyona DN, Dida GO
Zoonoses Public Health 2019 Feb;66(1):140-154. Epub 2018 Dec 21 doi: 10.1111/zph.12547. PMID: 30575317
Ng-Nguyen D, Stevenson MA, Traub RJ
Parasit Vectors 2017 Mar 21;10(1):150. doi: 10.1186/s13071-017-2085-9. PMID: 28320455Free PMC Article
Devleesschauwer B, Ale A, Torgerson P, Praet N, Maertens de Noordhout C, Pandey BD, Pun SB, Lake R, Vercruysse J, Joshi DD, Havelaar AH, Duchateau L, Dorny P, Speybroeck N
PLoS Negl Trop Dis 2014;8(1):e2634. Epub 2014 Jan 2 doi: 10.1371/journal.pntd.0002634. PMID: 24392178Free PMC Article
Neghina R, Neghina AM
Foodborne Pathog Dis 2011 Sep;8(9):943-8. Epub 2011 Apr 27 doi: 10.1089/fpd.2011.0861. PMID: 21524198

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