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Substance dependence

MedGen UID:
20989
•Concept ID:
C0038580
•
Mental or Behavioral Dysfunction
Synonyms: Addiction, Substance; Chemical Dependence; Chemical Dependences; Dependence, Chemical; Dependence, Substance; Dependences, Chemical; Substance Addiction; Substance Dependence
SNOMED CT: Substance dependence (1254812006)
 
Monarch Initiative: MONDO:0004938

Definition

The psychological or physiological need to take a substance in order to experience its effects or to avoid the effects of its absence. [from MONDO]

Professional guidelines

PubMed

Treatment resistance in psychiatry: state of the art and new directions.
Howes OD, Thase ME, Pillinger T
Mol Psychiatry 2022 Jan;27(1):58-72. Epub 2021 Jul 13 doi: 10.1038/s41380-021-01200-3. PMID: 34257409Free PMC Article
Psychosocial impact of COVID-19.
Dubey S, Biswas P, Ghosh R, Chatterjee S, Dubey MJ, Chatterjee S, Lahiri D, Lavie CJ
Diabetes Metab Syndr 2020 Sep-Oct;14(5):779-788. Epub 2020 May 27 doi: 10.1016/j.dsx.2020.05.035. PMID: 32526627Free PMC Article
Prevalence, psychosocial correlates and service utilization of depressive and anxiety disorders in Hong Kong: the Hong Kong Mental Morbidity Survey (HKMMS).
Lam LC, Wong CS, Wang MJ, Chan WC, Chen EY, Ng RM, Hung SF, Cheung EF, Sham PC, Chiu HF, Lam M, Chang WC, Lee EH, Chiang TP, Lau JT, van Os J, Lewis G, Bebbington P
Soc Psychiatry Psychiatr Epidemiol 2015 Sep;50(9):1379-88. Epub 2015 Feb 8 doi: 10.1007/s00127-015-1014-5. PMID: 25660760

Recent clinical studies

Etiology

Androgen abuse: Risks and adverse effects in men.
Grant B, Hyams E, Davies R, Minhas S, Jayasena CN
Ann N Y Acad Sci 2024 Aug;1538(1):56-70. Epub 2024 Jul 23 doi: 10.1111/nyas.15187. PMID: 39041466
Family-Based Treatments for Adolescent Substance Use.
Horigian VE, Anderson AR, Szapocznik J
Child Adolesc Psychiatr Clin N Am 2016 Oct;25(4):603-28. Epub 2016 Aug 3 doi: 10.1016/j.chc.2016.06.001. PMID: 27613341Free PMC Article
Addiction and suicide: A review.
Yuodelis-Flores C, Ries RK
Am J Addict 2015 Mar;24(2):98-104. Epub 2015 Feb 2 doi: 10.1111/ajad.12185. PMID: 25644860
The genetics of substance dependence.
Wang JC, Kapoor M, Goate AM
Annu Rev Genomics Hum Genet 2012;13:241-61. Epub 2012 Jun 11 doi: 10.1146/annurev-genom-090711-163844. PMID: 22703173Free PMC Article
Epilepsy and dependence.
Martinove M
Neuropsychopharmacol Hung 2010 Mar;12(1):295-300. PMID: 20305305

Diagnosis

Gambling Disorder as an Addictive Disorder and Creative Psychopharmacotherapy.
Hasanović M, Kuldija A, Pajević I, Jakovljević M, Hasanović M
Psychiatr Danub 2021 Spring-Summer;33(Suppl 4):1118-1129. PMID: 35354178
History of the Concept of Addiction.
Nathan PE, Conrad M, Skinstad AH
Annu Rev Clin Psychol 2016;12:29-51. Epub 2015 Nov 11 doi: 10.1146/annurev-clinpsy-021815-093546. PMID: 26565120
Development and validation of a smartphone addiction scale (SAS).
Kwon M, Lee JY, Won WY, Park JW, Min JA, Hahn C, Gu X, Choi JH, Kim DJ
PLoS One 2013;8(2):e56936. Epub 2013 Feb 27 doi: 10.1371/journal.pone.0056936. PMID: 23468893Free PMC Article
Alcoholism & depression.
Hall M
Home Healthc Nurse 2012 Oct;30(9):543-50; quiz 550-2. doi: 10.1097/NHH.0b013e31826a6719. PMID: 23026991
Epilepsy and dependence.
Martinove M
Neuropsychopharmacol Hung 2010 Mar;12(1):295-300. PMID: 20305305

Therapy

Ketamine for the acute treatment of severe suicidal ideation: double blind, randomised placebo controlled trial.
Abbar M, Demattei C, El-Hage W, Llorca PM, Samalin L, Demaricourt P, Gaillard R, Courtet P, Vaiva G, Gorwood P, Fabbro P, Jollant F
BMJ 2022 Feb 2;376:e067194. doi: 10.1136/bmj-2021-067194. PMID: 35110300Free PMC Article
DARK Classics in Chemical Neuroscience: Loperamide.
Malinky CA, Lindsley CW, Han C
ACS Chem Neurosci 2021 Aug 18;12(16):2964-2973. Epub 2021 Aug 4 doi: 10.1021/acschemneuro.1c00382. PMID: 34346690
Effectiveness of a housing support team intervention with a recovery-oriented approach on hospital and emergency department use by homeless people with severe mental illness: a randomised controlled trial.
Tinland A, Loubière S, Boucekine M, Boyer L, Fond G, Girard V, Auquier P
Epidemiol Psychiatr Sci 2020 Sep 30;29:e169. doi: 10.1017/S2045796020000785. PMID: 32996442Free PMC Article
Trajectories and mental health-related predictors of perceived discrimination and stigma among homeless adults with mental illness.
Mejia-Lancheros C, Lachaud J, O'Campo P, Wiens K, Nisenbaum R, Wang R, Hwang SW, Stergiopoulos V
PLoS One 2020;15(2):e0229385. Epub 2020 Feb 27 doi: 10.1371/journal.pone.0229385. PMID: 32106225Free PMC Article
Dimethyltryptamine: Endogenous Role and Therapeutic Potential.
Rodrigues AV, Almeida FJ, Vieira-Coelho MA
J Psychoactive Drugs 2019 Sep-Oct;51(4):299-310. Epub 2019 Apr 25 doi: 10.1080/02791072.2019.1602291. PMID: 31018803

Prognosis

Trajectories and mental health-related predictors of perceived discrimination and stigma among homeless adults with mental illness.
Mejia-Lancheros C, Lachaud J, O'Campo P, Wiens K, Nisenbaum R, Wang R, Hwang SW, Stergiopoulos V
PLoS One 2020;15(2):e0229385. Epub 2020 Feb 27 doi: 10.1371/journal.pone.0229385. PMID: 32106225Free PMC Article
Addiction theory matters-Why there is no dependence on caffeine or antidepressant medication.
Heinz A, Daedelow LS, Wackerhagen C, Di Chiara G
Addict Biol 2020 Mar;25(2):e12735. Epub 2019 Mar 21 doi: 10.1111/adb.12735. PMID: 30896084
Impulsiveness and burn patients.
Palmu R, Partonen T, Suominen K, Vuola J
Burns 2019 Feb;45(1):63-68. Epub 2018 Oct 2 doi: 10.1016/j.burns.2018.08.017. PMID: 30286951
Global statistics on alcohol, tobacco and illicit drug use: 2017 status report.
Peacock A, Leung J, Larney S, Colledge S, Hickman M, Rehm J, Giovino GA, West R, Hall W, Griffiths P, Ali R, Gowing L, Marsden J, Ferrari AJ, Grebely J, Farrell M, Degenhardt L
Addiction 2018 Oct;113(10):1905-1926. Epub 2018 Jun 4 doi: 10.1111/add.14234. PMID: 29749059
A gradient of childhood self-control predicts health, wealth, and public safety.
Moffitt TE, Arseneault L, Belsky D, Dickson N, Hancox RJ, Harrington H, Houts R, Poulton R, Roberts BW, Ross S, Sears MR, Thomson WM, Caspi A
Proc Natl Acad Sci U S A 2011 Feb 15;108(7):2693-8. Epub 2011 Jan 24 doi: 10.1073/pnas.1010076108. PMID: 21262822Free PMC Article

Clinical prediction guides

Differences in the associations between psychoactive substance use and alexithymia: A series of Meta-analyses.
Kun B, Alpay P, Bodó V, Molnár Á, Horváth A, Karsai S, Somlai RS, Takacs ZK, Kökönyei G
Clin Psychol Rev 2023 Jul;103:102297. Epub 2023 Jun 2 doi: 10.1016/j.cpr.2023.102297. PMID: 37290244
Trajectories and mental health-related predictors of perceived discrimination and stigma among homeless adults with mental illness.
Mejia-Lancheros C, Lachaud J, O'Campo P, Wiens K, Nisenbaum R, Wang R, Hwang SW, Stergiopoulos V
PLoS One 2020;15(2):e0229385. Epub 2020 Feb 27 doi: 10.1371/journal.pone.0229385. PMID: 32106225Free PMC Article
Development of the Yale Food Addiction Scale Version 2.0.
Gearhardt AN, Corbin WR, Brownell KD
Psychol Addict Behav 2016 Feb;30(1):113-21. doi: 10.1037/adb0000136. PMID: 26866783
Gambling and problem gambling in The Netherlands.
Goudriaan AE
Addiction 2014 Jul;109(7):1066-71. Epub 2013 Jun 6 doi: 10.1111/add.12213. PMID: 23742239
Development and validation of a smartphone addiction scale (SAS).
Kwon M, Lee JY, Won WY, Park JW, Min JA, Hahn C, Gu X, Choi JH, Kim DJ
PLoS One 2013;8(2):e56936. Epub 2013 Feb 27 doi: 10.1371/journal.pone.0056936. PMID: 23468893Free PMC Article

Recent systematic reviews

The Tolerability and Safety of Psilocybin in Psychiatric and Substance-Dependence Conditions: A Systematic Review.
Kaminski D, Reinert JP
Ann Pharmacother 2024 Aug;58(8):811-826. Epub 2023 Oct 30 doi: 10.1177/10600280231205645. PMID: 37902038
Nature of glutamate alterations in substance dependence: A systematic review and meta-analysis of proton magnetic resonance spectroscopy studies.
Chen T, Tan H, Lei H, Li X, Wu Q, Xu X, Ye Y, Zhong N, Du J, Jiang H, Su H, Zhao M
Psychiatry Res Neuroimaging 2021 Sep 30;315:111329. Epub 2021 Jul 7 doi: 10.1016/j.pscychresns.2021.111329. PMID: 34271295
Substance Use and Recidivism Outcomes for Prison-Based Drug and Alcohol Interventions.
de Andrade D, Ritchie J, Rowlands M, Mann E, Hides L
Epidemiol Rev 2018 Jun 1;40(1):121-133. doi: 10.1093/epirev/mxy004. PMID: 29733373
Mobile phone messaging for illicit drug and alcohol dependence: A systematic review of the literature.
Tofighi B, Nicholson JM, McNeely J, Muench F, Lee JD
Drug Alcohol Rev 2017 Jul;36(4):477-491. Epub 2017 May 5 doi: 10.1111/dar.12535. PMID: 28474374
A review of the psychometric properties of the CRAFFT instrument: 1999-2010.
Dhalla S, Zumbo BD, Poole G
Curr Drug Abuse Rev 2011 Mar;4(1):57-64. doi: 10.2174/1874473711104010057. PMID: 21466499

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