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Phlegmon

MedGen UID:
45874
Concept ID:
C0031557
Pathologic Function
Synonym: Phlegmonous cellulitis
SNOMED CT: Phlegmon (190280006); Phlegmonous cellulitis (190280006)

Definition

Purulent inflammation of the cellular or areolar tissue. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPhlegmon

Professional guidelines

PubMed

Mitchell KB, Johnson HM
Surg Clin North Am 2022 Dec;102(6):973-987. doi: 10.1016/j.suc.2022.06.002. PMID: 36335932
Di Saverio S, Podda M, De Simone B, Ceresoli M, Augustin G, Gori A, Boermeester M, Sartelli M, Coccolini F, Tarasconi A, De' Angelis N, Weber DG, Tolonen M, Birindelli A, Biffl W, Moore EE, Kelly M, Soreide K, Kashuk J, Ten Broek R, Gomes CA, Sugrue M, Davies RJ, Damaskos D, Leppäniemi A, Kirkpatrick A, Peitzman AB, Fraga GP, Maier RV, Coimbra R, Chiarugi M, Sganga G, Pisanu A, De' Angelis GL, Tan E, Van Goor H, Pata F, Di Carlo I, Chiara O, Litvin A, Campanile FC, Sakakushev B, Tomadze G, Demetrashvili Z, Latifi R, Abu-Zidan F, Romeo O, Segovia-Lohse H, Baiocchi G, Costa D, Rizoli S, Balogh ZJ, Bendinelli C, Scalea T, Ivatury R, Velmahos G, Andersson R, Kluger Y, Ansaloni L, Catena F
World J Emerg Surg 2020 Apr 15;15(1):27. doi: 10.1186/s13017-020-00306-3. PMID: 32295644Free PMC Article
Wilkins T, Embry K, George R
Am Fam Physician 2013 May 1;87(9):612-20. PMID: 23668524

Recent clinical studies

Etiology

García-Callejo FJ, Alba-García JR, Orozco-Núñez S, Martínez-Giménez L, Balaguer-García R, Ruescas-Gómez L
Acta Otorrinolaringol Esp (Engl Ed) 2023 Mar-Apr;74(2):108-115. Epub 2023 Mar 9 doi: 10.1016/j.otoeng.2022.04.003. PMID: 36906064Free PMC Article
Thompson DT, Hrabe JE
Gastroenterol Clin North Am 2021 Jun;50(2):475-488. Epub 2021 Apr 23 doi: 10.1016/j.gtc.2021.02.014. PMID: 34024453
Darwazeh G, Cunningham SC, Kowdley GC
Am Surg 2016 Jan;82(1):11-5. PMID: 26802841
Brook I
Am J Emerg Med 2016 Mar;34(3):609-10. Epub 2015 Dec 2 doi: 10.1016/j.ajem.2015.11.063. PMID: 26689849
Wilkins T, Embry K, George R
Am Fam Physician 2013 May 1;87(9):612-20. PMID: 23668524

Diagnosis

Douglas P
Womens Health (Lond) 2022 Jan-Dec;18:17455057221091349. doi: 10.1177/17455057221091349. PMID: 35441543Free PMC Article
Thompson DT, Hrabe JE
Gastroenterol Clin North Am 2021 Jun;50(2):475-488. Epub 2021 Apr 23 doi: 10.1016/j.gtc.2021.02.014. PMID: 34024453
Di Saverio S, Podda M, De Simone B, Ceresoli M, Augustin G, Gori A, Boermeester M, Sartelli M, Coccolini F, Tarasconi A, De' Angelis N, Weber DG, Tolonen M, Birindelli A, Biffl W, Moore EE, Kelly M, Soreide K, Kashuk J, Ten Broek R, Gomes CA, Sugrue M, Davies RJ, Damaskos D, Leppäniemi A, Kirkpatrick A, Peitzman AB, Fraga GP, Maier RV, Coimbra R, Chiarugi M, Sganga G, Pisanu A, De' Angelis GL, Tan E, Van Goor H, Pata F, Di Carlo I, Chiara O, Litvin A, Campanile FC, Sakakushev B, Tomadze G, Demetrashvili Z, Latifi R, Abu-Zidan F, Romeo O, Segovia-Lohse H, Baiocchi G, Costa D, Rizoli S, Balogh ZJ, Bendinelli C, Scalea T, Ivatury R, Velmahos G, Andersson R, Kluger Y, Ansaloni L, Catena F
World J Emerg Surg 2020 Apr 15;15(1):27. doi: 10.1186/s13017-020-00306-3. PMID: 32295644Free PMC Article
Raghavan M, Lazzeri E, Palestro CJ
Semin Nucl Med 2018 Mar;48(2):131-147. Epub 2018 Feb 6 doi: 10.1053/j.semnuclmed.2017.11.001. PMID: 29452617
Wilkins T, Embry K, George R
Am Fam Physician 2013 May 1;87(9):612-20. PMID: 23668524

Therapy

García-Callejo FJ, Alba-García JR, Orozco-Núñez S, Martínez-Giménez L, Balaguer-García R, Ruescas-Gómez L
Acta Otorrinolaringol Esp (Engl Ed) 2023 Mar-Apr;74(2):108-115. Epub 2023 Mar 9 doi: 10.1016/j.otoeng.2022.04.003. PMID: 36906064Free PMC Article
Di Saverio S, Podda M, De Simone B, Ceresoli M, Augustin G, Gori A, Boermeester M, Sartelli M, Coccolini F, Tarasconi A, De' Angelis N, Weber DG, Tolonen M, Birindelli A, Biffl W, Moore EE, Kelly M, Soreide K, Kashuk J, Ten Broek R, Gomes CA, Sugrue M, Davies RJ, Damaskos D, Leppäniemi A, Kirkpatrick A, Peitzman AB, Fraga GP, Maier RV, Coimbra R, Chiarugi M, Sganga G, Pisanu A, De' Angelis GL, Tan E, Van Goor H, Pata F, Di Carlo I, Chiara O, Litvin A, Campanile FC, Sakakushev B, Tomadze G, Demetrashvili Z, Latifi R, Abu-Zidan F, Romeo O, Segovia-Lohse H, Baiocchi G, Costa D, Rizoli S, Balogh ZJ, Bendinelli C, Scalea T, Ivatury R, Velmahos G, Andersson R, Kluger Y, Ansaloni L, Catena F
World J Emerg Surg 2020 Apr 15;15(1):27. doi: 10.1186/s13017-020-00306-3. PMID: 32295644Free PMC Article
López JJ, Deans KJ, Minneci PC
Curr Opin Pediatr 2017 Jun;29(3):358-362. doi: 10.1097/MOP.0000000000000487. PMID: 28306630
Brook I
Am J Emerg Med 2016 Mar;34(3):609-10. Epub 2015 Dec 2 doi: 10.1016/j.ajem.2015.11.063. PMID: 26689849
Wilkins T, Embry K, George R
Am Fam Physician 2013 May 1;87(9):612-20. PMID: 23668524

Prognosis

Mahomed N, Kilborn T, Smit EJ, Chu WCW, Young CYM, Koranteng N, Kasznia-Brown J, Winant AJ, Lee EY, Sodhi KS
Pediatr Radiol 2023 Aug;53(9):1799-1828. Epub 2023 May 23 doi: 10.1007/s00247-023-05648-z. PMID: 37217783Free PMC Article
Mitchell KB, Johnson HM, Rodríguez JM, Eglash A, Scherzinger C, Zakarija-Grkovic I, Cash KW, Berens P, Miller B; Academy of Breastfeeding Medicine
Breastfeed Med 2022 May;17(5):360-376. doi: 10.1089/bfm.2022.29207.kbm. PMID: 35576513
Raghavan M, Lazzeri E, Palestro CJ
Semin Nucl Med 2018 Mar;48(2):131-147. Epub 2018 Feb 6 doi: 10.1053/j.semnuclmed.2017.11.001. PMID: 29452617
Darwazeh G, Cunningham SC, Kowdley GC
Am Surg 2016 Jan;82(1):11-5. PMID: 26802841
Place RJ, Simmang CL, Huber PJ Jr
South Med J 2000 Jan;93(1):76-9. PMID: 10653074

Clinical prediction guides

Di Saverio S, Podda M, De Simone B, Ceresoli M, Augustin G, Gori A, Boermeester M, Sartelli M, Coccolini F, Tarasconi A, De' Angelis N, Weber DG, Tolonen M, Birindelli A, Biffl W, Moore EE, Kelly M, Soreide K, Kashuk J, Ten Broek R, Gomes CA, Sugrue M, Davies RJ, Damaskos D, Leppäniemi A, Kirkpatrick A, Peitzman AB, Fraga GP, Maier RV, Coimbra R, Chiarugi M, Sganga G, Pisanu A, De' Angelis GL, Tan E, Van Goor H, Pata F, Di Carlo I, Chiara O, Litvin A, Campanile FC, Sakakushev B, Tomadze G, Demetrashvili Z, Latifi R, Abu-Zidan F, Romeo O, Segovia-Lohse H, Baiocchi G, Costa D, Rizoli S, Balogh ZJ, Bendinelli C, Scalea T, Ivatury R, Velmahos G, Andersson R, Kluger Y, Ansaloni L, Catena F
World J Emerg Surg 2020 Apr 15;15(1):27. doi: 10.1186/s13017-020-00306-3. PMID: 32295644Free PMC Article
Raghavan M, Lazzeri E, Palestro CJ
Semin Nucl Med 2018 Mar;48(2):131-147. Epub 2018 Feb 6 doi: 10.1053/j.semnuclmed.2017.11.001. PMID: 29452617
Cheng Y, Xiong X, Lu J, Wu S, Zhou R, Cheng N
Cochrane Database Syst Rev 2017 Jun 2;6(6):CD011670. doi: 10.1002/14651858.CD011670.pub2. PMID: 28574593Free PMC Article
Tan JP, Barazanchi AW, Singh PP, Hill AG, Maccormick AD
Int J Surg 2016 Feb;26:43-52. Epub 2016 Jan 9 doi: 10.1016/j.ijsu.2016.01.005. PMID: 26777741
Wyrzykowski AD, Feliciano DV, George TA, Tremblay LN, Rozycki GS, Murphy TW, Dente CJ
Am Surg 2005 Aug;71(8):653-6; discussion 656-7. PMID: 16217947

Recent systematic reviews

Zhou S, Cheng Y, Cheng N, Gong J, Tu B
Cochrane Database Syst Rev 2024 May 2;5(5):CD011670. doi: 10.1002/14651858.CD011670.pub3. PMID: 38695830Free PMC Article
Solis-Pazmino P, Oka K, La K, Termeie O, Figueroa LA, Pilatuna E, Solis-Pazmino D, Harnegie MP, Cohen J, Barnajian M, Nasseri Y
Langenbecks Arch Surg 2023 Nov 9;408(1):432. doi: 10.1007/s00423-023-03164-0. PMID: 37940770Free PMC Article
Cheng Y, Xiong X, Lu J, Wu S, Zhou R, Cheng N
Cochrane Database Syst Rev 2017 Jun 2;6(6):CD011670. doi: 10.1002/14651858.CD011670.pub2. PMID: 28574593Free PMC Article
Darwazeh G, Cunningham SC, Kowdley GC
Am Surg 2016 Jan;82(1):11-5. PMID: 26802841
Tan JP, Barazanchi AW, Singh PP, Hill AG, Maccormick AD
Int J Surg 2016 Feb;26:43-52. Epub 2016 Jan 9 doi: 10.1016/j.ijsu.2016.01.005. PMID: 26777741

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