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Aggressive periodontitis(PPP; JPD; JP)

MedGen UID:
10661
•Concept ID:
C0031106
•
Disease or Syndrome
Synonyms: Aggressive Periodontitis; Circumpubertal Periodontitis; Early Onset Periodontitis; Early-Onset Periodontitides; Early-Onset Periodontitis; Juvenile Periodontitides; Juvenile Periodontitis; Periodontitides, Early-Onset; Periodontitides, Juvenile; Periodontitis, Aggressive; Periodontitis, Circumpubertal; Periodontitis, Early-Onset; Periodontitis, Juvenile; Periodontitis, Prepubertal; Prepubertal Periodontitis
SNOMED CT: Aggressive periodontitis (449908004); Juvenile periodontitis (449908004)
 
OMIM®: 170650

Definition

Inflammation and loss of PERIODONTIUM that is characterized by rapid attachment loss and bone destruction in the presence of little local factors such as DENTAL PLAQUE and DENTAL CALCULUS. This highly destructive form of periodontitis often occurs in young people and was called early-onset periodontitis, but this disease also appears in old people. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAggressive periodontitis

Professional guidelines

PubMed

Orthodontic treatment in periodontally compromised patients: a systematic review.
Erbe C, Heger S, Kasaj A, Berres M, Wehrbein H
Clin Oral Investig 2023 Jan;27(1):79-89. Epub 2022 Dec 11 doi: 10.1007/s00784-022-04822-1. PMID: 36502508Free PMC Article
Evidence-Based Update on Diagnosis and Management of Gingivitis and Periodontitis.
Kumar S
Dent Clin North Am 2019 Jan;63(1):69-81. Epub 2018 Oct 29 doi: 10.1016/j.cden.2018.08.005. PMID: 30447793
Nonsurgical periodontal treatment.
Aimetti M
Int J Esthet Dent 2014 Summer;9(2):251-67. PMID: 24765632

Recent clinical studies

Etiology

Aggressive periodontitis and NOD2 variants.
Mizuno N, Kume K, Nagatani Y, Matsuda S, Iwata T, Ouhara K, Kajiya M, Takeda K, Matsuda Y, Tada Y, Ohsawa R, Morino H, Mihara K, Fujita T, Kawaguchi H, Shiba H, Kawakami H, Kurihara H
J Hum Genet 2020 Oct;65(10):841-846. Epub 2020 May 19 doi: 10.1038/s10038-020-0777-z. PMID: 32424308
Classification and diagnosis of aggressive periodontitis.
Fine DH, Patil AG, Loos BG
J Periodontol 2018 Jun;89 Suppl 1:S103-S119. doi: 10.1002/JPER.16-0712. PMID: 29926947
Treatment of aggressive periodontitis.
Teughels W, Dhondt R, Dekeyser C, Quirynen M
Periodontol 2000 2014 Jun;65(1):107-33. doi: 10.1111/prd.12020. PMID: 24738589
Epidemiology and demographics of aggressive periodontitis.
Susin C, Haas AN, Albandar JM
Periodontol 2000 2014 Jun;65(1):27-45. doi: 10.1111/prd.12019. PMID: 24738585
Aggressive periodontitis: case definition and diagnostic criteria.
Albandar JM
Periodontol 2000 2014 Jun;65(1):13-26. doi: 10.1111/prd.12014. PMID: 24738584

Diagnosis

Evidence-Based Update on Diagnosis and Management of Gingivitis and Periodontitis.
Kumar S
Dent Clin North Am 2019 Jan;63(1):69-81. Epub 2018 Oct 29 doi: 10.1016/j.cden.2018.08.005. PMID: 30447793
Staging and grading of periodontitis: Framework and proposal of a new classification and case definition.
Tonetti MS, Greenwell H, Kornman KS
J Clin Periodontol 2018 Jun;45 Suppl 20:S149-S161. doi: 10.1111/jcpe.12945. PMID: 29926495
Aggressive periodontitis.
Kar K
J Calif Dent Assoc 2011 Jun;39(6):372-4. PMID: 21823494
Diagnosis and classification of periodontal disease.
Highfield J
Aust Dent J 2009 Sep;54 Suppl 1:S11-26. doi: 10.1111/j.1834-7819.2009.01140.x. PMID: 19737262
Periodontal diseases in the child and adolescent.
Oh TJ, Eber R, Wang HL
J Clin Periodontol 2002 May;29(5):400-10. doi: 10.1034/j.1600-051x.2002.290504.x. PMID: 12060422

Therapy

Periodontitis and stroke: A Mendelian randomization study.
Ma C, Wu M, Gao J, Liu C, Xie Y, Lv Q, Zhang X
Brain Behav 2023 Feb;13(2):e2888. Epub 2023 Jan 9 doi: 10.1002/brb3.2888. PMID: 36621868Free PMC Article
Orthodontic treatment in periodontally compromised patients: a systematic review.
Erbe C, Heger S, Kasaj A, Berres M, Wehrbein H
Clin Oral Investig 2023 Jan;27(1):79-89. Epub 2022 Dec 11 doi: 10.1007/s00784-022-04822-1. PMID: 36502508Free PMC Article
Vitamin D and Periodontitis: A Systematic Review and Meta-Analysis.
Machado V, Lobo S, Proença L, Mendes JJ, Botelho J
Nutrients 2020 Jul 22;12(8) doi: 10.3390/nu12082177. PMID: 32708032Free PMC Article
Orthodontic treatment in patients with aggressive periodontitis.
Carvalho CV, Saraiva L, Bauer FPF, Kimura RY, Souto MLS, Bernardo CC, Pannuti CM, Romito GA, Pustiglioni FE
Am J Orthod Dentofacial Orthop 2018 Apr;153(4):550-557. doi: 10.1016/j.ajodo.2017.08.018. PMID: 29602347
Periodontal diseases.
Kinane DF, Stathopoulou PG, Papapanou PN
Nat Rev Dis Primers 2017 Jun 22;3:17038. doi: 10.1038/nrdp.2017.38. PMID: 28805207

Prognosis

Periodontitis and stroke: A Mendelian randomization study.
Ma C, Wu M, Gao J, Liu C, Xie Y, Lv Q, Zhang X
Brain Behav 2023 Feb;13(2):e2888. Epub 2023 Jan 9 doi: 10.1002/brb3.2888. PMID: 36621868Free PMC Article
Management of periodontic-endodontic lesion in aggressive periodontitis-9 months follow-up: Report of a case.
Kavarthapu A, Malaiappan S
Indian J Dent Res 2019 Jan-Feb;30(1):149-153. doi: 10.4103/ijdr.IJDR_417_17. PMID: 30900677
Staging and grading of periodontitis: Framework and proposal of a new classification and case definition.
Tonetti MS, Greenwell H, Kornman KS
J Periodontol 2018 Jun;89 Suppl 1:S159-S172. doi: 10.1002/JPER.18-0006. PMID: 29926952
Staging and grading of periodontitis: Framework and proposal of a new classification and case definition.
Tonetti MS, Greenwell H, Kornman KS
J Clin Periodontol 2018 Jun;45 Suppl 20:S149-S161. doi: 10.1111/jcpe.12945. PMID: 29926495
Nonsurgical periodontal treatment.
Aimetti M
Int J Esthet Dent 2014 Summer;9(2):251-67. PMID: 24765632

Clinical prediction guides

Antibiotics against Periodontal Biofilms.
Guentsch A
Monogr Oral Sci 2021;29:119-132. Epub 2020 Dec 21 doi: 10.1159/000510188. PMID: 33427226
Classification and diagnosis of aggressive periodontitis.
Fine DH, Patil AG, Loos BG
J Periodontol 2018 Jun;89 Suppl 1:S103-S119. doi: 10.1002/JPER.16-0712. PMID: 29926947
Aggressive periodontitis: The unsolved mystery.
Clark D, Febbraio M, Levin L
Quintessence Int 2017;48(2):103-111. doi: 10.3290/j.qi.a37387. PMID: 28133644
Aggressive periodontitis: case definition and diagnostic criteria.
Albandar JM
Periodontol 2000 2014 Jun;65(1):13-26. doi: 10.1111/prd.12014. PMID: 24738584
Early-onset periodontitis.
Tonetti MS, Mombelli A
Ann Periodontol 1999 Dec;4(1):39-53. doi: 10.1902/annals.1999.4.1.39. PMID: 10863374

Recent systematic reviews

Orthodontic treatment in periodontally compromised patients: a systematic review.
Erbe C, Heger S, Kasaj A, Berres M, Wehrbein H
Clin Oral Investig 2023 Jan;27(1):79-89. Epub 2022 Dec 11 doi: 10.1007/s00784-022-04822-1. PMID: 36502508Free PMC Article
Adjunctive systemic antimicrobials for the non-surgical treatment of periodontitis.
Khattri S, Kumbargere Nagraj S, Arora A, Eachempati P, Kusum CK, Bhat KG, Johnson TM, Lodi G
Cochrane Database Syst Rev 2020 Nov 16;11(11):CD012568. doi: 10.1002/14651858.CD012568.pub2. PMID: 33197289Free PMC Article
Vitamin D and Periodontitis: A Systematic Review and Meta-Analysis.
Machado V, Lobo S, Proença L, Mendes JJ, Botelho J
Nutrients 2020 Jul 22;12(8) doi: 10.3390/nu12082177. PMID: 32708032Free PMC Article
Antimicrobial photodynamic therapy for the treatment of periodontitis and peri-implantitis: An American Academy of Periodontology best evidence review.
Chambrone L, Wang HL, Romanos GE
J Periodontol 2018 Jul;89(7):783-803. doi: 10.1902/jop.2017.170172. PMID: 30133749
Association between depression and periodontitis: a systematic review and meta-analysis.
Araújo MM, Martins CC, Costa LC, Cota LO, Faria RL, Cunha FA, Costa FO
J Clin Periodontol 2016 Mar;43(3):216-28. Epub 2016 Mar 6 doi: 10.1111/jcpe.12510. PMID: 26743451

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