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Odontogenic cyst

MedGen UID:
14461
•Concept ID:
C0028879
•
Disease or Syndrome
Synonyms: Cyst, Odontogenic; Cysts, Odontogenic; Odontogenic Cyst; Odontogenic Cysts
SNOMED CT: Odontogenic cyst (235110008); Odontogenic cyst (28727003); Developmental odontogenic cyst (28727003)
 
Monarch Initiative: MONDO:0006328

Definition

A cyst in the jaw that arises from tissues of tooth development. [from NCI]

Professional guidelines

PubMed

Digital pathology-based artificial intelligence models for differential diagnosis and prognosis of sporadic odontogenic keratocysts.
Cai X, Zhang H, Wang Y, Zhang J, Li T
Int J Oral Sci 2024 Feb 26;16(1):16. doi: 10.1038/s41368-024-00287-y. PMID: 38403665Free PMC Article
Differential diagnosis between calcifying odontogenic cyst and adenomatoid odontogenic tumor by computed tomography images.
Okura S, Igarashi C, Wakae-Morita S, Eda T, Ito H, Nakashima K, Sugisaki M, Ito Y, Kobayashi K
Oral Radiol 2022 Jan;38(1):99-104. Epub 2021 Apr 27 doi: 10.1007/s11282-021-00531-9. PMID: 33907948
Odontogenic keratocysts/keratocystic odontogenic tumours: biological characteristics, clinical manifestation and treatment.
Pazdera J, Kolar Z, Zboril V, Tvrdy P, Pink R
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2014 Jun;158(2):170-4. Epub 2012 Jun 1 doi: 10.5507/bp.2012.048. PMID: 23073530

Recent clinical studies

Etiology

Differential diagnosis between calcifying odontogenic cyst and adenomatoid odontogenic tumor by computed tomography images.
Okura S, Igarashi C, Wakae-Morita S, Eda T, Ito H, Nakashima K, Sugisaki M, Ito Y, Kobayashi K
Oral Radiol 2022 Jan;38(1):99-104. Epub 2021 Apr 27 doi: 10.1007/s11282-021-00531-9. PMID: 33907948
Comparative analysis between developmental and inflammatory odontogenic cysts: retrospective study and literature review.
Kammer PV, Mello FW, Rivero ERC
Oral Maxillofac Surg 2020 Mar;24(1):73-84. Epub 2019 Dec 19 doi: 10.1007/s10006-019-00816-8. PMID: 31858303
Odontogenic Cysts.
Rajendra Santosh AB
Dent Clin North Am 2020 Jan;64(1):105-119. Epub 2019 Oct 18 doi: 10.1016/j.cden.2019.08.002. PMID: 31735221
Intraosseous mucoepidermoid carcinoma: Outcome review.
Merna C, Kita A, Wester J, Diaz-Aguilar D, Goldstein JD, Palma Diaz F, Blackwell K, St John MA
Laryngoscope 2018 May;128(5):1083-1092. Epub 2017 Aug 22 doi: 10.1002/lary.26832. PMID: 28833169
Calcifying epithelial odontogenic cyst.
Manohar B, Baidya D, Shetty N, Mathur A, Makhijani B
J Exp Ther Oncol 2017 Nov;12(2):151-156. PMID: 29161784

Diagnosis

Pediatric Oral Pathology: Odontogenic Cysts.
Summersgill KF
Pediatr Dev Pathol 2023 Nov-Dec;26(6):609-620. Epub 2023 May 22 doi: 10.1177/10935266231176245. PMID: 37212213
Unicystic Ameloblastoma of Mandible: A Case Report.
Rayamajhi S, Shrestha S, Shakya S, Bhandari S, Twayana AR, Shahi K
JNMA J Nepal Med Assoc 2022 Jul 1;60(251):657-660. doi: 10.31729/jnma.7566. PMID: 36705195Free PMC Article
Odontogenic and Developmental Oral Lesions in Pediatric Patients.
Bilodeau EA, Hunter KD
Head Neck Pathol 2021 Mar;15(1):71-84. Epub 2021 Mar 15 doi: 10.1007/s12105-020-01284-3. PMID: 33723756Free PMC Article
Odontogenic Cysts and Neoplasms.
Bilodeau EA, Collins BM
Surg Pathol Clin 2017 Mar;10(1):177-222. Epub 2016 Dec 29 doi: 10.1016/j.path.2016.10.006. PMID: 28153133
Ameloblastic Carcinoma.
Gunaratne DA, Coleman HG, Lim L, Morgan GJ
Am J Case Rep 2015 Jul 1;16:415-9. doi: 10.12659/AJCR.893918. PMID: 26126621Free PMC Article

Therapy

The Incidence of Devitalization of Vital Teeth Associated with Pathologies of the Jaws Following Surgical Intervention: A Mixed-case Study.
Alharbi MA, Alghamdi A, Kattan SA, Austah O, Othman B, Haddad S, Aljumaiah A, Barayan MA, Attar EA
J Contemp Dent Pract 2023 Oct 1;24(10):750-756. doi: 10.5005/jp-journals-10024-3567. PMID: 38152907
5-fluorouacil in the treatment of odontogenic keratocysts-incidence of recurrence and inferior alveolar nerve paresthesia: a systematic review.
Melean LP, Guerrero LM, Lopez L
Oral Maxillofac Surg 2023 Sep;27(3):489-496. Epub 2022 Jun 18 doi: 10.1007/s10006-022-01090-x. PMID: 35715708
A comparative study of the expression of cyclin D1, COX-2, and KI-67 in odontogenic keratocyst vs. ameloblastoma vs. orthokeratinized odontogenic cyst.
Martín-Hernán F, Campo-Trapero J, Cano-Sánchez J, García-Martín R, Martínez-López M, Ballestín-Carcavilla C
Rev Esp Patol 2022 Apr-Jun;55(2):90-95. Epub 2021 Aug 28 doi: 10.1016/j.patol.2021.05.005. PMID: 35483774
Comparing the efficacy of sinus irrigation with traditional Caldwell-Luc procedure following odontogenic cyst surgery involving the maxillary sinus.
Gang N, JiaMin C, Ye W, FuPing X, HuanHuan L, LiSong L
Sci Rep 2021 Sep 13;11(1):18136. doi: 10.1038/s41598-021-97477-z. PMID: 34518580Free PMC Article
Reclassification and treatment of odontogenic keratocysts: A cohort study.
Ribeiro-Júnior O, Borba AM, Alves CAF, Gouveia MM, Deboni MCZ, Naclério-Homem MDG
Braz Oral Res 2017 Dec 18;31:e98. doi: 10.1590/1807-3107bor-2017.vol31.0098. PMID: 29267660

Prognosis

Digital pathology-based artificial intelligence models for differential diagnosis and prognosis of sporadic odontogenic keratocysts.
Cai X, Zhang H, Wang Y, Zhang J, Li T
Int J Oral Sci 2024 Feb 26;16(1):16. doi: 10.1038/s41368-024-00287-y. PMID: 38403665Free PMC Article
Ghost cells unveiled: A comprehensive review.
Garg A, Malhotra R, Urs AB
J Oral Biosci 2022 Jun;64(2):202-209. Epub 2022 Apr 6 doi: 10.1016/j.job.2022.03.005. PMID: 35398253
Odontogenic and Developmental Oral Lesions in Pediatric Patients.
Bilodeau EA, Hunter KD
Head Neck Pathol 2021 Mar;15(1):71-84. Epub 2021 Mar 15 doi: 10.1007/s12105-020-01284-3. PMID: 33723756Free PMC Article
Intraosseous mucoepidermoid carcinoma: Outcome review.
Merna C, Kita A, Wester J, Diaz-Aguilar D, Goldstein JD, Palma Diaz F, Blackwell K, St John MA
Laryngoscope 2018 May;128(5):1083-1092. Epub 2017 Aug 22 doi: 10.1002/lary.26832. PMID: 28833169
Odontogenic Cysts and Neoplasms.
Bilodeau EA, Collins BM
Surg Pathol Clin 2017 Mar;10(1):177-222. Epub 2016 Dec 29 doi: 10.1016/j.path.2016.10.006. PMID: 28153133

Clinical prediction guides

Histopathological and histomorphometric analysis of glandular odontogenic cyst-A diagnostic aid.
Heiliczer S, Shmuly T, Avishai G, Zlotogorski-Hurvitz A, Vered M, Mamber L, Kaplan I
Oral Dis 2023 Nov;29(8):3306-3312. Epub 2022 Dec 15 doi: 10.1111/odi.14415. PMID: 36305228
Buccal bifurcation cyst: A case series and review of the literature.
Ruddocks LA, Fitzpatrick SG, Bhattacharyya I, Islam MN, Cohen DM
J Am Dent Assoc 2022 May;153(5):421-428. Epub 2022 Feb 4 doi: 10.1016/j.adaj.2021.10.002. PMID: 35125168
Differential diagnosis between calcifying odontogenic cyst and adenomatoid odontogenic tumor by computed tomography images.
Okura S, Igarashi C, Wakae-Morita S, Eda T, Ito H, Nakashima K, Sugisaki M, Ito Y, Kobayashi K
Oral Radiol 2022 Jan;38(1):99-104. Epub 2021 Apr 27 doi: 10.1007/s11282-021-00531-9. PMID: 33907948
Intraosseous mucoepidermoid carcinoma: Outcome review.
Merna C, Kita A, Wester J, Diaz-Aguilar D, Goldstein JD, Palma Diaz F, Blackwell K, St John MA
Laryngoscope 2018 May;128(5):1083-1092. Epub 2017 Aug 22 doi: 10.1002/lary.26832. PMID: 28833169
Calcifying odontogenic cysts.
Rojo R, Prados-Frutos JC, Gutierrez Lázaro I, Herguedas Alonso JA
J Stomatol Oral Maxillofac Surg 2017 Apr;118(2):122-124. Epub 2017 Feb 11 doi: 10.1016/j.jormas.2016.10.007. PMID: 28345512

Recent systematic reviews

Hybrid odontogenic lesions: A systematic review of 203 cases reported in the literature.
Pontes FSC, Mosqueda-Taylor A, de Souza LL, de Paula LP, Batista LAL, Rodrigues-Fernandes CI, Paiva E Costa AM, de Abreu MC, Gomez RS, de Oliveira EM, Fonseca FP, Rahimi S, Brennan PA, Pontes HAR
J Oral Pathol Med 2022 Jan;51(1):5-12. Epub 2021 Sep 20 doi: 10.1111/jop.13238. PMID: 34469012
Cyst or Tumor? A systematic review and meta-analysis on the expression of p53 marker in Odontogenic Keratocysts.
Slusarenko da Silva Y, Stoelinga PJW, Grillo R, da Graça Naclério-Homem M
J Craniomaxillofac Surg 2021 Dec;49(12):1101-1106. Epub 2021 Sep 28 doi: 10.1016/j.jcms.2021.09.015. PMID: 34620539
Frequency of odontogenic cysts and tumors: a systematic review.
Johnson NR, Gannon OM, Savage NW, Batstone MD
J Investig Clin Dent 2014 Feb;5(1):9-14. Epub 2013 Jun 14 doi: 10.1111/jicd.12044. PMID: 23766099
Orthokeratinized odontogenic cyst: a systematic review.
Macdonald-Jankowski DS
Dentomaxillofac Radiol 2010 Dec;39(8):455-67. doi: 10.1259/dmfr/19728573. PMID: 21062939Free PMC Article
Glandular odontogenic cyst: systematic review.
Macdonald-Jankowski DS
Dentomaxillofac Radiol 2010 Mar;39(3):127-39. doi: 10.1259/dmfr/30943934. PMID: 20203274Free PMC Article

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