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Neoplasm Invasiveness

MedGen UID:
10210
•Concept ID:
C0027626
•
Pathologic Function
Synonyms: Invasion, Neoplasm; Invasiveness, Neoplasm; Neoplasm Invasion

Definition

Ability of neoplasms to infiltrate and actively destroy surrounding tissue. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNeoplasm Invasiveness

Professional guidelines

PubMed

Urinary symptoms in women receiving carboplatin/paclitaxel for treatment of gynecologic cancers.
Strauchon CJ, Dengler KL, Gruber DD, Katebi Kashi P, Aungst MJ, Trikhacheva A, Bicher A, Von Pechmann W
Int J Gynecol Cancer 2020 Sep;30(9):1418-1423. Epub 2020 Jul 12 doi: 10.1136/ijgc-2020-001529. PMID: 32655011
Conservative Management Following Complete Clinical Response to Neoadjuvant Chemotherapy of Muscle Invasive Bladder Cancer: Contemporary Outcomes of a Multi-Institutional Cohort Study.
Mazza P, Moran GW, Li G, Robins DJ, Matulay JT, Herr HW, Decastro GJ, McKiernan JM, Anderson CB
J Urol 2018 Nov;200(5):1005-1013. Epub 2018 May 19 doi: 10.1016/j.juro.2018.05.078. PMID: 29787740Free PMC Article
Incidence, Clinicopathological Risk Factors, Management and Outcomes of Nonmuscle Invasive Recurrence after Complete Response to Trimodality Therapy for Muscle Invasive Bladder Cancer.
Sanchez A, Wszolek MF, Niemierko A, Clayman RH, Drumm M, Rodríguez D, Feldman AS, Dahl DM, Heney NM, Shipley WU, Zietman AL, Efstathiou JA
J Urol 2018 Feb;199(2):407-415. Epub 2017 Sep 1 doi: 10.1016/j.juro.2017.08.106. PMID: 28870862

Recent clinical studies

Etiology

Perineural invasion-associated biomarkers for tumor development.
Liu Q, Ma Z, Cao Q, Zhao H, Guo Y, Liu T, Li J
Biomed Pharmacother 2022 Nov;155:113691. Epub 2022 Sep 12 doi: 10.1016/j.biopha.2022.113691. PMID: 36095958
Nipple-Sparing Mastectomy.
Smith BL, Coopey SB
Adv Surg 2018 Sep;52(1):113-126. Epub 2018 Jun 20 doi: 10.1016/j.yasu.2018.03.008. PMID: 30098607
Invisible Retinoblastoma.
Saktanasate J, Vongkulsiri S, Khoo CT
JAMA Ophthalmol 2015 Jul;133(7):e151123. Epub 2015 Jul 9 doi: 10.1001/jamaophthalmol.2015.1123. PMID: 26158440
Pseudomyxoma peritonei.
Smeenk RM, Bruin SC, van Velthuysen ML, Verwaal VJ
Curr Probl Surg 2008 Aug;45(8):527-75. doi: 10.1067/j.cpsurg.2008.04.003. PMID: 18590843
The aged breast.
Walker RA, Martin CV
J Pathol 2007 Jan;211(2):232-40. doi: 10.1002/path.2079. PMID: 17200937

Diagnosis

Tumor-Associated Macrophages (TAMs) in Colorectal Cancer (CRC): From Mechanism to Therapy and Prognosis.
Wang H, Tian T, Zhang J
Int J Mol Sci 2021 Aug 6;22(16) doi: 10.3390/ijms22168470. PMID: 34445193Free PMC Article
Exosomes in cancer development, metastasis, and immunity.
Zhang L, Yu D
Biochim Biophys Acta Rev Cancer 2019 Apr;1871(2):455-468. Epub 2019 Apr 30 doi: 10.1016/j.bbcan.2019.04.004. PMID: 31047959Free PMC Article
Epithelial Mesenchymal Transition in Tumor Metastasis.
Mittal V
Annu Rev Pathol 2018 Jan 24;13:395-412. doi: 10.1146/annurev-pathol-020117-043854. PMID: 29414248
Aggressive angiomyxoma.
Sutton BJ, Laudadio J
Arch Pathol Lab Med 2012 Feb;136(2):217-21. doi: 10.5858/arpa.2011-0056-RS. PMID: 22288973
Invasion and metastasis.
Steeg PS
Curr Opin Oncol 1992 Feb;4(1):134-41. doi: 10.1097/00001622-199202000-00018. PMID: 1375513

Therapy

Approaches to Non-Muscle-Invasive Bladder Cancer.
Slovacek H, Zhuo J, Taylor JM
Curr Oncol Rep 2021 Jul 16;23(9):105. doi: 10.1007/s11912-021-01091-1. PMID: 34269918
Defining cisplatin eligibility in patients with muscle-invasive bladder cancer.
Jiang DM, Gupta S, Kitchlu A, Meraz-Munoz A, North SA, Alimohamed NS, Blais N, Sridhar SS
Nat Rev Urol 2021 Feb;18(2):104-114. Epub 2021 Jan 11 doi: 10.1038/s41585-020-00404-6. PMID: 33432181
Treatment of muscle-invasive and advanced bladder cancer in 2020.
Patel VG, Oh WK, Galsky MD
CA Cancer J Clin 2020 Sep;70(5):404-423. Epub 2020 Aug 7 doi: 10.3322/caac.21631. PMID: 32767764
Inflammatory fibroblasts in cancer.
Lim H, Moon A
Arch Pharm Res 2016 Aug;39(8):1021-31. Epub 2016 Jul 6 doi: 10.1007/s12272-016-0787-8. PMID: 27384063
Twenty-year follow-up of a randomized trial comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer.
Fisher B, Anderson S, Bryant J, Margolese RG, Deutsch M, Fisher ER, Jeong JH, Wolmark N
N Engl J Med 2002 Oct 17;347(16):1233-41. doi: 10.1056/NEJMoa022152. PMID: 12393820

Prognosis

HPV Vaccination and the Risk of Invasive Cervical Cancer.
Lei J, Ploner A, Elfström KM, Wang J, Roth A, Fang F, Sundström K, Dillner J, Sparén P
N Engl J Med 2020 Oct 1;383(14):1340-1348. doi: 10.1056/NEJMoa1917338. PMID: 32997908
Active Surveillance as First-Line Management of Papillary Microcarcinoma.
Ito Y, Miyauchi A
Annu Rev Med 2019 Jan 27;70:369-379. Epub 2018 Sep 19 doi: 10.1146/annurev-med-051517-125510. PMID: 30230964
Endometrial cancer.
Sorosky JI
Obstet Gynecol 2008 Feb;111(2 Pt 1):436-47. doi: 10.1097/AOG.0b013e318162f690. PMID: 18238985
Neuroendocrine tumours (carcinoids) of the appendix.
Stinner B, Rothmund M
Best Pract Res Clin Gastroenterol 2005 Oct;19(5):729-38. doi: 10.1016/j.bpg.2005.06.003. PMID: 16253897
Dermatofibrosarcoma protuberans.
Gloster HM Jr
J Am Acad Dermatol 1996 Sep;35(3 Pt 1):355-74; quiz 375-6. doi: 10.1016/s0190-9622(96)90597-6. PMID: 8784271

Clinical prediction guides

Ultrasound-based deep learning radiomics in the assessment of pathological complete response to neoadjuvant chemotherapy in locally advanced breast cancer.
Jiang M, Li CL, Luo XM, Chuan ZR, Lv WZ, Li X, Cui XW, Dietrich CF
Eur J Cancer 2021 Apr;147:95-105. Epub 2021 Feb 24 doi: 10.1016/j.ejca.2021.01.028. PMID: 33639324
Is gastric cancer becoming a rare disease? A global assessment of predicted incidence trends to 2035.
Arnold M, Park JY, Camargo MC, Lunet N, Forman D, Soerjomataram I
Gut 2020 May;69(5):823-829. Epub 2020 Jan 30 doi: 10.1136/gutjnl-2019-320234. PMID: 32001553Free PMC Article
Progressive tissue biomarker profiling in non-muscle-invasive bladder cancer.
D'Andrea D, Hassler MR, Abufaraj M, Soria F, Ertl IE, Ilijazi D, Mari A, Foerster B, Egger G, Shariat SF
Expert Rev Anticancer Ther 2018 Jul;18(7):695-703. Epub 2018 May 9 doi: 10.1080/14737140.2018.1474104. PMID: 29737231
Risk stratification in extramammary Paget disease.
Cohen JM, Granter SR, Werchniak AE
Clin Exp Dermatol 2015 Jul;40(5):473-8. Epub 2015 May 26 doi: 10.1111/ced.12690. PMID: 26011765
Primary cardiac tumors.
Leja MJ, Shah DJ, Reardon MJ
Tex Heart Inst J 2011;38(3):261-2. PMID: 21720466Free PMC Article

Recent systematic reviews

Diagnosis and Treatment of Non-Muscle Invasive Bladder Cancer: AUA/SUO Guideline.
Chang SS, Boorjian SA, Chou R, Clark PE, Daneshmand S, Konety BR, Pruthi R, Quale DZ, Ritch CR, Seigne JD, Skinner EC, Smith ND, McKiernan JM
J Urol 2016 Oct;196(4):1021-9. Epub 2016 Jun 16 doi: 10.1016/j.juro.2016.06.049. PMID: 27317986
Neoadjuvant Chemotherapy for Muscle-Invasive Bladder Cancer: A Systematic Review and Two-Step Meta-Analysis.
Yin M, Joshi M, Meijer RP, Glantz M, Holder S, Harvey HA, Kaag M, Fransen van de Putte EE, Horenblas S, Drabick JJ
Oncologist 2016 Jun;21(6):708-15. Epub 2016 Apr 6 doi: 10.1634/theoncologist.2015-0440. PMID: 27053504Free PMC Article
Risk Factors for Cutaneous Squamous Cell Carcinoma Recurrence, Metastasis, and Disease-Specific Death: A Systematic Review and Meta-analysis.
Thompson AK, Kelley BF, Prokop LJ, Murad MH, Baum CL
JAMA Dermatol 2016 Apr;152(4):419-28. doi: 10.1001/jamadermatol.2015.4994. PMID: 26762219Free PMC Article
Carboplatin- or cisplatin-based chemotherapy in first-line treatment of small-cell lung cancer: the COCIS meta-analysis of individual patient data.
Rossi A, Di Maio M, Chiodini P, Rudd RM, Okamoto H, Skarlos DV, Früh M, Qian W, Tamura T, Samantas E, Shibata T, Perrone F, Gallo C, Gridelli C, Martelli O, Lee SM
J Clin Oncol 2012 May 10;30(14):1692-8. Epub 2012 Apr 2 doi: 10.1200/JCO.2011.40.4905. PMID: 22473169
Neoadjuvant chemotherapy in invasive bladder cancer: update of a systematic review and meta-analysis of individual patient data advanced bladder cancer (ABC) meta-analysis collaboration.
Advanced Bladder Cancer (ABC) Meta-analysis Collaboration
Eur Urol 2005 Aug;48(2):202-5; discussion 205-6. Epub 2005 Apr 21 doi: 10.1016/j.eururo.2005.04.006. PMID: 15939524

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