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Musculoskeletal pain

MedGen UID:: 6472
•Concept ID:: C0026858
•: Finding

Synonyms:	Musculoskeletal Pain; Musculoskeletal Pains; Pain, Musculoskeletal; Pains, Musculoskeletal
SNOMED CT:	Rheumatic pain (279069000); Musculoskeletal pain (279069000)

Definition

Pain that originates in the bones, muscles, tendons or ligaments. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVMusculoskeletal pain

Phenotypic abnormality
- Abnormality of the musculoskeletal system
  - Abnormality of the musculature
    - Abnormal skeletal muscle morphology
      - Myopathy
        Musculoskeletal pain
        Myalgia
        COVID-19-Associated Myalgia
        Exercise-induced myalgia
        Gastrocnemius myalgia
        Pelvic girdle pain

Professional guidelines

PubMed

Fibromyalgia: Pathogenesis, Mechanisms, Diagnosis and Treatment Options Update.

Siracusa R, Paola RD, Cuzzocrea S, Impellizzeri D
Int J Mol Sci 2021 Apr 9;22(8) doi: 10.3390/ijms22083891. PMID: 33918736 Free PMC Article

Four common types of bursitis: diagnosis and management.

Aaron DL, Patel A, Kayiaros S, Calfee R
J Am Acad Orthop Surg 2011 Jun;19(6):359-67. doi: 10.5435/00124635-201106000-00006. PMID: 21628647

Central post-stroke pain: clinical characteristics, pathophysiology, and management.

Klit H, Finnerup NB, Jensen TS
Lancet Neurol 2009 Sep;8(9):857-68. doi: 10.1016/S1474-4422(09)70176-0. PMID: 19679277

See all (674)

Recent clinical studies

Etiology

Which Portion of Physiotherapy Treatments' Effect Is Not Attributable to the Specific Effects in People With Musculoskeletal Pain? A Meta-Analysis of Randomized Placebo-Controlled Trials.

Ezzatvar Y, Dueñas L, Balasch-Bernat M, Lluch-Girbés E, Rossettini G
J Orthop Sports Phys Ther 2024 Jun;54(6):391-399. doi: 10.2519/jospt.2024.12126. PMID: 38602164

Text Neck Syndrome in Children and Adolescents.

David D, Giannini C, Chiarelli F, Mohn A
Int J Environ Res Public Health 2021 Feb 7;18(4) doi: 10.3390/ijerph18041565. PMID: 33562204 Free PMC Article

Musculoskeletal pain and menopause.

Watt FE
Post Reprod Health 2018 Mar;24(1):34-43. Epub 2018 Feb 7 doi: 10.1177/2053369118757537. PMID: 29412042

Trigger Point Dry Needling.

J Orthop Sports Phys Ther 2017 Mar;47(3):150. doi: 10.2519/jospt.2017.0502. PMID: 28245743

Chronic Pain: Where the Body Meets the Brain.

Crofford LJ
Trans Am Clin Climatol Assoc 2015;126:167-83. PMID: 26330672 Free PMC Article

See all (5358)

Diagnosis

Text Neck Syndrome in Children and Adolescents.

David D, Giannini C, Chiarelli F, Mohn A
Int J Environ Res Public Health 2021 Feb 7;18(4) doi: 10.3390/ijerph18041565. PMID: 33562204 Free PMC Article

Musculoskeletal pain and menopause.

Watt FE
Post Reprod Health 2018 Mar;24(1):34-43. Epub 2018 Feb 7 doi: 10.1177/2053369118757537. PMID: 29412042

The assessment of musculoskeletal pain.

Hawker GA
Clin Exp Rheumatol 2017 Sep-Oct;35 Suppl 107(5):8-12. Epub 2017 Sep 28 PMID: 28967361

Growing Pains.

Lehman PJ, Carl RL
Sports Health 2017 Mar-Apr;9(2):132-138. Epub 2017 Feb 8 doi: 10.1177/1941738117692533. PMID: 28177851 Free PMC Article

The efficacy of pain neuroscience education on musculoskeletal pain: A systematic review of the literature.

Louw A, Zimney K, Puentedura EJ, Diener I
Physiother Theory Pract 2016 Jul;32(5):332-55. Epub 2016 Jun 28 doi: 10.1080/09593985.2016.1194646. PMID: 27351541

See all (3209)

Therapy

Which Portion of Physiotherapy Treatments' Effect Is Not Attributable to the Specific Effects in People With Musculoskeletal Pain? A Meta-Analysis of Randomized Placebo-Controlled Trials.

Ezzatvar Y, Dueñas L, Balasch-Bernat M, Lluch-Girbés E, Rossettini G
J Orthop Sports Phys Ther 2024 Jun;54(6):391-399. doi: 10.2519/jospt.2024.12126. PMID: 38602164

Acupuncture and Chronic Musculoskeletal Pain.

Zhang Y, Wang C
Curr Rheumatol Rep 2020 Sep 25;22(11):80. doi: 10.1007/s11926-020-00954-z. PMID: 32978666 Free PMC Article

Cognitive functional therapy compared with a group-based exercise and education intervention for chronic low back pain: a multicentre randomised controlled trial (RCT).

O'Keeffe M, O'Sullivan P, Purtill H, Bargary N, O'Sullivan K
Br J Sports Med 2020 Jul;54(13):782-789. Epub 2019 Oct 19 doi: 10.1136/bjsports-2019-100780. PMID: 31630089 Free PMC Article

Acupuncture for Chronic Pain: Update of an Individual Patient Data Meta-Analysis.

Vickers AJ, Vertosick EA, Lewith G, MacPherson H, Foster NE, Sherman KJ, Irnich D, Witt CM, Linde K; Acupuncture Trialists' Collaboration
J Pain 2018 May;19(5):455-474. Epub 2017 Dec 2 doi: 10.1016/j.jpain.2017.11.005. PMID: 29198932 Free PMC Article

The Effectiveness of Trigger Point Dry Needling for Musculoskeletal Conditions by Physical Therapists: A Systematic Review and Meta-analysis.

Gattie E, Cleland JA, Snodgrass S
J Orthop Sports Phys Ther 2017 Mar;47(3):133-149. Epub 2017 Feb 3 doi: 10.2519/jospt.2017.7096. PMID: 28158962

See all (3376)

Prognosis

Global, regional, and national burden of neck pain, 1990-2020, and projections to 2050: a systematic analysis of the Global Burden of Disease Study 2021.

GBD 2021 Neck Pain Collaborators
Lancet Rheumatol 2024 Mar;6(3):e142-e155. doi: 10.1016/S2665-9913(23)00321-1. PMID: 38383088 Free PMC Article

Vascular involvement in axial spondyloarthropathies.

Prati C, Demougeot C, Guillot X, Sondag M, Verhoeven F, Wendling D
Joint Bone Spine 2019 Mar;86(2):159-163. Epub 2018 May 19 doi: 10.1016/j.jbspin.2018.05.003. PMID: 29787813

Adult Degenerative Lumbar Scoliosis.

Wong E, Altaf F, Oh LJ, Gray RJ
Orthopedics 2017 Nov 1;40(6):e930-e939. Epub 2017 Jun 9 doi: 10.3928/01477447-20170606-02. PMID: 28598493

Proximal Hamstring Tendinosis and Partial Ruptures.

Startzman AN, Fowler O, Carreira D
Orthopedics 2017 Jul 1;40(4):e574-e582. Epub 2017 Feb 14 doi: 10.3928/01477447-20170208-05. PMID: 28195608

Management of lumbar spinal stenosis.

Lurie J, Tomkins-Lane C
BMJ 2016 Jan 4;352:h6234. doi: 10.1136/bmj.h6234. PMID: 26727925 Free PMC Article

See all (1990)

Clinical prediction guides

The Tampa Scale of Kinesiophobia: A Systematic Review of Its Psychometric Properties in People With Musculoskeletal Pain.

Dupuis F, Cherif A, Batcho C, Massé-Alarie H, Roy JS
Clin J Pain 2023 May 1;39(5):236-247. doi: 10.1097/AJP.0000000000001104. PMID: 36917768

Besharati A, Daneshmandi H, Zareh K, Fakherpour A, Zoaktafi M
Int J Occup Saf Ergon 2020 Sep;26(3):632-638. Epub 2018 Nov 13 doi: 10.1080/10803548.2018.1501238. PMID: 30015596

The Effectiveness of Trigger Point Dry Needling for Musculoskeletal Conditions by Physical Therapists: A Systematic Review and Meta-analysis.

Gattie E, Cleland JA, Snodgrass S
J Orthop Sports Phys Ther 2017 Mar;47(3):133-149. Epub 2017 Feb 3 doi: 10.2519/jospt.2017.7096. PMID: 28158962

Clinical indicators of 'nociceptive', 'peripheral neuropathic' and 'central' mechanisms of musculoskeletal pain. A Delphi survey of expert clinicians.

Smart KM, Blake C, Staines A, Doody C
Man Ther 2010 Feb;15(1):80-7. Epub 2009 Aug 12 doi: 10.1016/j.math.2009.07.005. PMID: 19679504

Minimal clinically important changes in chronic musculoskeletal pain intensity measured on a numerical rating scale.

Salaffi F, Stancati A, Silvestri CA, Ciapetti A, Grassi W
Eur J Pain 2004 Aug;8(4):283-91. doi: 10.1016/j.ejpain.2003.09.004. PMID: 15207508

See all (3552)

Recent systematic reviews

Effectiveness of Pain Neuroscience Education in Patients with Chronic Musculoskeletal Pain and Central Sensitization: A Systematic Review.

Lepri B, Romani D, Storari L, Barbari V
Int J Environ Res Public Health 2023 Feb 24;20(5) doi: 10.3390/ijerph20054098. PMID: 36901108 Free PMC Article

What does best practice care for musculoskeletal pain look like? Eleven consistent recommendations from high-quality clinical practice guidelines: systematic review.

Lin I, Wiles L, Waller R, Goucke R, Nagree Y, Gibberd M, Straker L, Maher CG, O'Sullivan PPB
Br J Sports Med 2020 Jan;54(2):79-86. Epub 2019 Mar 2 doi: 10.1136/bjsports-2018-099878. PMID: 30826805

Trigger Point Dry Needling.

J Orthop Sports Phys Ther 2017 Mar;47(3):150. doi: 10.2519/jospt.2017.0502. PMID: 28245743

The Effectiveness of Trigger Point Dry Needling for Musculoskeletal Conditions by Physical Therapists: A Systematic Review and Meta-analysis.

Gattie E, Cleland JA, Snodgrass S
J Orthop Sports Phys Ther 2017 Mar;47(3):133-149. Epub 2017 Feb 3 doi: 10.2519/jospt.2017.7096. PMID: 28158962

Management of lumbar spinal stenosis.

Lurie J, Tomkins-Lane C
BMJ 2016 Jan 4;352:h6234. doi: 10.1136/bmj.h6234. PMID: 26727925 Free PMC Article

See all (630)

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Musculoskeletal pain

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

Table of contents

Practice guidelines

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