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Mastitis

MedGen UID:
9901
•Concept ID:
C0024894
•
Disease or Syndrome
Synonyms: breast infection; breast inflammation; inflammation of breast; inflammatory breast disease; inflammatory disease of breast; mastitis
 
HPO: HP:0040407
Monarch Initiative: MONDO:0006849

Definition

Mastitis is defined as an inflammation of the breast and may or may not be accompanied by infection. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMastitis

Professional guidelines

PubMed

Management of Mastitis, Abscess, and Fistula.
Snider HC
Surg Clin North Am 2022 Dec;102(6):1103-1116. doi: 10.1016/j.suc.2022.06.007. PMID: 36335928
Management of granulomatous lobular mastitis: an international multidisciplinary consensus (2021 edition).
Yuan QQ, Xiao SY, Farouk O, Du YT, Sheybani F, Tan QT, Akbulut S, Cetin K, Alikhassi A, Yaghan RJ, Durur-Subasi I, Altintoprak F, Eom TI, Alper F, Hasbahceci M, Martínez-Ramos D, Oztekin PS, Kwong A, Pluguez-Turull CW, Brownson KE, Chandanwale S, Habibi M, Lan LY, Zhou R, Zeng XT, Bai J, Bai JW, Chen QR, Chen X, Zha XM, Dai WJ, Dai ZJ, Feng QY, Gao QJ, Gao RF, Han BS, Hou JX, Hou W, Liao HY, Luo H, Liu ZR, Lu JH, Luo B, Ma XP, Qian J, Qin JY, Wei W, Wei G, Xu LY, Xue HC, Yang HW, Yang WG, Zhang CJ, Zhang F, Zhang GX, Zhang SK, Zhang SQ, Zhang YQ, Zhang YP, Zhang SC, Zhao DW, Zheng XM, Zheng LW, Xu GR, Zhou WB, Wu GS
Mil Med Res 2022 Apr 26;9(1):20. doi: 10.1186/s40779-022-00380-5. PMID: 35473758Free PMC Article
Treatment of Staphylococcus aureus Infections.
David MZ, Daum RS
Curr Top Microbiol Immunol 2017;409:325-383. doi: 10.1007/82_2017_42. PMID: 28900682

Recent clinical studies

Etiology

Idiopathic Granulomatous Mastitis.
Dilaveri C, Degnim A, Lee C, DeSimone D, Moldoveanu D, Ghosh K
Breast J 2024;2024:6693720. Epub 2024 Jan 25 doi: 10.1155/2024/6693720. PMID: 38304866Free PMC Article
Risk Factors, Symptoms, and Treatment of Lactational Mastitis.
Louis-Jacques AF, Berwick M, Mitchell KB
JAMA 2023 Feb 21;329(7):588-589. doi: 10.1001/jama.2023.0004. PMID: 36701134
Incidence of and Risk Factors for Lactational Mastitis: A Systematic Review.
Wilson E, Woodd SL, Benova L
J Hum Lact 2020 Nov;36(4):673-686. Epub 2020 Apr 14 doi: 10.1177/0890334420907898. PMID: 32286139Free PMC Article
Postdelivery Emergencies.
Wheaton N, Al-Abdullah A, Haertlein T
Emerg Med Clin North Am 2019 May;37(2):287-300. doi: 10.1016/j.emc.2019.01.014. PMID: 30940373
Management of mastitis in breastfeeding women.
Spencer JP
Am Fam Physician 2008 Sep 15;78(6):727-31. PMID: 18819238

Diagnosis

Idiopathic Granulomatous Mastitis.
Dilaveri C, Degnim A, Lee C, DeSimone D, Moldoveanu D, Ghosh K
Breast J 2024;2024:6693720. Epub 2024 Jan 25 doi: 10.1155/2024/6693720. PMID: 38304866Free PMC Article
Management of Mastitis, Abscess, and Fistula.
Snider HC
Surg Clin North Am 2022 Dec;102(6):1103-1116. doi: 10.1016/j.suc.2022.06.007. PMID: 36335928
Inflammatory diseases of the breast.
Scott DM
Best Pract Res Clin Obstet Gynaecol 2022 Sep;83:72-87. Epub 2021 Dec 8 doi: 10.1016/j.bpobgyn.2021.11.013. PMID: 34991976
Idiopathic Granulomatous Mastitis: Etiology, Clinical Manifestation, Diagnosis and Treatment.
Yin Y, Liu X, Meng Q, Han X, Zhang H, Lv Y
J Invest Surg 2022 Mar;35(3):709-720. Epub 2021 Mar 10 doi: 10.1080/08941939.2021.1894516. PMID: 33691563
Mastitis, Breast Abscess, and Granulomatous Mastitis.
Omranipour R, Vasigh M
Adv Exp Med Biol 2020;1252:53-61. doi: 10.1007/978-3-030-41596-9_7. PMID: 32816262

Therapy

Risk Factors, Symptoms, and Treatment of Lactational Mastitis.
Louis-Jacques AF, Berwick M, Mitchell KB
JAMA 2023 Feb 21;329(7):588-589. doi: 10.1001/jama.2023.0004. PMID: 36701134
The preventive and therapeutic effects of probiotics on mastitis: A systematic review and meta-analysis.
Yu Q, Xu C, Wang M, Zhu J, Yu L, Yang Z, Liu S, Gao X
PLoS One 2022;17(9):e0274467. Epub 2022 Sep 9 doi: 10.1371/journal.pone.0274467. PMID: 36084006Free PMC Article
An update on granulomatous mastitis: a rare and complex condition.
Coombe RF, Hamed H
Br J Hosp Med (Lond) 2021 May 2;82(5):1-7. Epub 2021 May 7 doi: 10.12968/hmed.2020.0718. PMID: 34076525
Treatments for breast engorgement during lactation.
Zakarija-Grkovic I, Stewart F
Cochrane Database Syst Rev 2020 Sep 18;9(9):CD006946. doi: 10.1002/14651858.CD006946.pub4. PMID: 32944940Free PMC Article
Management of mastitis in breastfeeding women.
Spencer JP
Am Fam Physician 2008 Sep 15;78(6):727-31. PMID: 18819238

Prognosis

Idiopathic Granulomatous Mastitis.
Dilaveri C, Degnim A, Lee C, DeSimone D, Moldoveanu D, Ghosh K
Breast J 2024;2024:6693720. Epub 2024 Jan 25 doi: 10.1155/2024/6693720. PMID: 38304866Free PMC Article
Academy of Breastfeeding Medicine Clinical Protocol #36: The Mastitis Spectrum, Revised 2022.
Mitchell KB, Johnson HM, Rodríguez JM, Eglash A, Scherzinger C, Zakarija-Grkovic I, Cash KW, Berens P, Miller B; Academy of Breastfeeding Medicine
Breastfeed Med 2022 May;17(5):360-376. doi: 10.1089/bfm.2022.29207.kbm. PMID: 35576513
Pathology of IgG4-related sclerosing mastitis.
Erivwo P, Turashvili G
J Clin Pathol 2021 Aug;74(8):475-482. Epub 2020 Dec 16 doi: 10.1136/jclinpath-2020-207029. PMID: 33328182
Incidence of and Risk Factors for Lactational Mastitis: A Systematic Review.
Wilson E, Woodd SL, Benova L
J Hum Lact 2020 Nov;36(4):673-686. Epub 2020 Apr 14 doi: 10.1177/0890334420907898. PMID: 32286139Free PMC Article
Infectious and Inflammatory Breast Disease.
Faguy K
Radiol Technol 2018 Jan;89(3):279M-295M. PMID: 29298955

Clinical prediction guides

Idiopathic Granulomatous Mastitis.
Dilaveri C, Degnim A, Lee C, DeSimone D, Moldoveanu D, Ghosh K
Breast J 2024;2024:6693720. Epub 2024 Jan 25 doi: 10.1155/2024/6693720. PMID: 38304866Free PMC Article
Idiopathic Granulomatous Mastitis: Etiology, Clinical Manifestation, Diagnosis and Treatment.
Yin Y, Liu X, Meng Q, Han X, Zhang H, Lv Y
J Invest Surg 2022 Mar;35(3):709-720. Epub 2021 Mar 10 doi: 10.1080/08941939.2021.1894516. PMID: 33691563
Idiopathic granulomatous mastitis: case series and clinical review.
Nguyen MH, Molland JG, Kennedy S, Gray TJ, Limaye S
Intern Med J 2021 Nov;51(11):1791-1797. Epub 2021 Oct 29 doi: 10.1111/imj.15112. PMID: 34713960
The gut microbiota contributes to the development of Staphylococcus aureus-induced mastitis in mice.
Hu X, Guo J, Zhao C, Jiang P, Maimai T, Yanyi L, Cao Y, Fu Y, Zhang N
ISME J 2020 Jul;14(7):1897-1910. Epub 2020 Apr 27 doi: 10.1038/s41396-020-0651-1. PMID: 32341472Free PMC Article
Granulomatous Lobular Mastitis.
Mahlab-Guri K, Asher I, Allweis T, Diment J, Sthoeger ZM, Mavor E
Isr Med Assoc J 2015 Aug;17(8):476-80. PMID: 26394488

Recent systematic reviews

The preventive and therapeutic effects of probiotics on mastitis: A systematic review and meta-analysis.
Yu Q, Xu C, Wang M, Zhu J, Yu L, Yang Z, Liu S, Gao X
PLoS One 2022;17(9):e0274467. Epub 2022 Sep 9 doi: 10.1371/journal.pone.0274467. PMID: 36084006Free PMC Article
Interventions for preventing mastitis after childbirth.
Crepinsek MA, Taylor EA, Michener K, Stewart F
Cochrane Database Syst Rev 2020 Sep 29;9(9):CD007239. doi: 10.1002/14651858.CD007239.pub4. PMID: 32987448Free PMC Article
Treatments for breast engorgement during lactation.
Zakarija-Grkovic I, Stewart F
Cochrane Database Syst Rev 2020 Sep 18;9(9):CD006946. doi: 10.1002/14651858.CD006946.pub4. PMID: 32944940Free PMC Article
Incidence of and Risk Factors for Lactational Mastitis: A Systematic Review.
Wilson E, Woodd SL, Benova L
J Hum Lact 2020 Nov;36(4):673-686. Epub 2020 Apr 14 doi: 10.1177/0890334420907898. PMID: 32286139Free PMC Article
Effectiveness of breast massage for the treatment of women with breastfeeding problems: a systematic review.
Anderson L, Kynoch K, Kildea S, Lee N
JBI Database System Rev Implement Rep 2019 Aug;17(8):1668-1694. doi: 10.11124/JBISRIR-2017-003932. PMID: 31135656

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