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Lymphocytic choriomeningitis

MedGen UID:
44220
•Concept ID:
C0024266
•
Disease or Syndrome
Synonyms: Armstrong Syndrome; Armstrong's Syndrome; Choriomeningitis, Lymphocytic; Encephalomyelitis, Lymphocytic Choriomeningitis Virus; Lymphocytic Choriomeningitis; Lymphocytic Choriomeningitis Virus Encephalomyelitis; Syndrome, Armstrong; Syndrome, Armstrong's
SNOMED CT: Lymphocytic choriomeningitis virus encephalomyelitis (397961002); Lymphocytic choriomeningitis (398136003); LCM - Lymphocytic choriomeningitis (398136003); Armstrong's disease (398136003); Infection caused by Lymphocytic choriomeningitis virus (721781004); Lymphocytic choriomeningitis virus infection (721781004); Encephalomyelitis caused by lymphocytic choriomeningitis virus (397961002); Lymphocytic meningitis (276064006); Lymphocytic meningoencephalitis (276817007); Meningitis caused by lymphocytic choriomeningitis virus (398136003)
 
Monarch Initiative: MONDO:0001449

Definition

Meningitis in which lymphocytes predominate in the cerebrospinal fluid. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLymphocytic choriomeningitis

Professional guidelines

PubMed

Tissue-resident memory T cells in the era of (Neo) adjuvant melanoma management.
Plunkett KR, Armitage JD, Inderjeeth AJ, McDonnell AM, Waithman J, Lau PKH
Front Immunol 2022;13:1048758. Epub 2022 Nov 16 doi: 10.3389/fimmu.2022.1048758. PMID: 36466880Free PMC Article
Large viral meningoencephalitis CSF serologic panel lacks utility in clinical decisions and outcomes.
Berklite L, Mitchell S, Wheeler SE
Clin Biochem 2022 Nov-Dec;109-110:17-22. Epub 2022 Sep 6 doi: 10.1016/j.clinbiochem.2022.09.001. PMID: 36075469
Assessment of risk for transplant-transmissible infectious encephalitis among deceased organ donors.
Smalley HK, Anand N, Buczek D, Buczek N, Lin T, Rajore T, Wacker M, Basavaraju SV, Gurbaxani BM, Hammett T, Keskinocak P, Sokol J, Kuehnert MJ
Transpl Infect Dis 2018 Oct;20(5):e12933. Epub 2018 Jun 15 doi: 10.1111/tid.12933. PMID: 29809311

Recent clinical studies

Etiology

Neurodevelopmental outcomes in congenital and perinatal infections.
Fortin O, Mulkey SB
Curr Opin Infect Dis 2023 Oct 1;36(5):405-413. Epub 2023 Jul 19 doi: 10.1097/QCO.0000000000000946. PMID: 37466092Free PMC Article
Progranulin mediates immune evasion of pancreatic ductal adenocarcinoma through regulation of MHCI expression.
Cheung PF, Yang J, Fang R, Borgers A, Krengel K, Stoffel A, Althoff K, Yip CW, Siu EHL, Ng LWC, Lang KS, Cham LB, Engel DR, Soun C, Cima I, Scheffler B, Striefler JK, Sinn M, Bahra M, Pelzer U, Oettle H, Markus P, Smeets EMM, Aarntzen EHJG, Savvatakis K, Liffers ST, Lueong SS, Neander C, Bazarna A, Zhang X, Paschen A, Crawford HC, Chan AWH, Cheung ST, Siveke JT
Nat Commun 2022 Jan 10;13(1):156. doi: 10.1038/s41467-021-27088-9. PMID: 35013174Free PMC Article
TOX reinforces the phenotype and longevity of exhausted T cells in chronic viral infection.
Alfei F, Kanev K, Hofmann M, Wu M, Ghoneim HE, Roelli P, Utzschneider DT, von Hoesslin M, Cullen JG, Fan Y, Eisenberg V, Wohlleber D, Steiger K, Merkler D, Delorenzi M, Knolle PA, Cohen CJ, Thimme R, Youngblood B, Zehn D
Nature 2019 Jul;571(7764):265-269. Epub 2019 Jun 17 doi: 10.1038/s41586-019-1326-9. PMID: 31207605
Infections: a double-edge sword in autoimmunity.
Shamriz O, Shoenfeld Y
Curr Opin Rheumatol 2018 Jul;30(4):365-372. doi: 10.1097/BOR.0000000000000490. PMID: 29847440
A Primate Model for Viral Hemorrhagic Fever.
Salvato MS, Lukashevich IS, Yang Y, Medina-Moreno S, Djavani M, Bryant J, Rodas JD, Zapata JC
Methods Mol Biol 2018;1604:279-290. doi: 10.1007/978-1-4939-6981-4_22. PMID: 28986843

Diagnosis

Neurodevelopmental outcomes in congenital and perinatal infections.
Fortin O, Mulkey SB
Curr Opin Infect Dis 2023 Oct 1;36(5):405-413. Epub 2023 Jul 19 doi: 10.1097/QCO.0000000000000946. PMID: 37466092Free PMC Article
Viral Encephalitis.
Venkatesan A, Murphy OC
Neurol Clin 2018 Nov;36(4):705-724. Epub 2018 Sep 20 doi: 10.1016/j.ncl.2018.07.001. PMID: 30366550
Congenital infections.
Bale JF Jr
Neurol Clin 2002 Nov;20(4):1039-60, vii. doi: 10.1016/s0733-8619(02)00014-2. PMID: 12616680
Viral meningitis.
Rotbart HA
Semin Neurol 2000;20(3):277-92. doi: 10.1055/s-2000-9427. PMID: 11051293
Zoonoses.
Goscienski PJ
Pediatr Infect Dis 1983 Jan-Feb;2(1):69-81. doi: 10.1097/00006454-198301000-00018. PMID: 6340080

Therapy

Platinum-Based Chemotherapy Attenuates the Effector Response of CD8 T Cells to Concomitant PD-1 Blockade.
Mariniello A, Nasti TH, Chang DY, Hashimoto M, Malik S, McManus DT, Lee J, McGuire DJ, Cardenas MA, Umana P, Nicolini V, Antia R, Saha A, Buchwald Z, Kissick H, Ghorani E, Novello S, Sangiolo D, Scagliotti GV, Ramalingam SS, Ahmed R
Clin Cancer Res 2024 May 1;30(9):1833-1845. doi: 10.1158/1078-0432.CCR-23-1316. PMID: 37992307Free PMC Article
PD-1 combination therapy with IL-2 modifies CD8(+) T cell exhaustion program.
Hashimoto M, Araki K, Cardenas MA, Li P, Jadhav RR, Kissick HT, Hudson WH, McGuire DJ, Obeng RC, Wieland A, Lee J, McManus DT, Ross JL, Im SJ, Lee J, Lin JX, Hu B, West EE, Scharer CD, Freeman GJ, Sharpe AH, Ramalingam SS, Pellerin A, Teichgräber V, Greenleaf WJ, Klein C, Goronzy JJ, Umaña P, Leonard WJ, Smith KA, Ahmed R
Nature 2022 Oct;610(7930):173-181. Epub 2022 Sep 28 doi: 10.1038/s41586-022-05257-0. PMID: 36171288Free PMC Article
JAK/STAT pathway inhibition sensitizes CD8 T cells to dexamethasone-induced apoptosis in hyperinflammation.
Meyer LK, Verbist KC, Albeituni S, Scull BP, Bassett RC, Stroh AN, Tillman H, Allen CE, Hermiston ML, Nichols KE
Blood 2020 Aug 6;136(6):657-668. doi: 10.1182/blood.2020006075. PMID: 32530039Free PMC Article
Liposome-based vaccines.
Schwendener RA, Ludewig B, Cerny A, Engler O
Methods Mol Biol 2010;605:163-75. doi: 10.1007/978-1-60327-360-2_11. PMID: 20072880
Interleukin-12.
Brunda MJ
J Leukoc Biol 1994 Feb;55(2):280-8. doi: 10.1002/jlb.55.2.280. PMID: 7905508

Prognosis

Immunomodulatory Role of Interferons in Viral and Bacterial Infections.
Mertowska P, Smolak K, Mertowski S, Grywalska E
Int J Mol Sci 2023 Jun 14;24(12) doi: 10.3390/ijms241210115. PMID: 37373262Free PMC Article
Zoonotic Potential of Brucella microti.
Hubálek Z, Křivanová A, Nesvadbová J, Rudolf I
Vector Borne Zoonotic Dis 2023 Aug;23(8):437-439. Epub 2023 Jun 27 doi: 10.1089/vbz.2022.0085. PMID: 37367199
Single MHC-I Expression Promotes Virus-Induced Liver Immunopathology.
Xu HC, Huang J, Pandyra AA, Pandey P, Wang R, Zhang Z, Zhuang Y, Gertzen CGW, Münk C, Herebian D, Borkhardt A, Recher M, Gohlke H, Esposito I, Oberbarnscheidt M, Häussinger D, Lang KS, Lang PA
Hepatol Commun 2022 Jul;6(7):1620-1633. Epub 2022 Feb 14 doi: 10.1002/hep4.1913. PMID: 35166071Free PMC Article
Prediction of cancer neoepitopes needs new rules.
Brennick CA, George MM, Srivastava PK, Karandikar SH
Semin Immunol 2020 Feb;47:101387. Epub 2020 Jan 14 doi: 10.1016/j.smim.2020.101387. PMID: 31952902
A Primate Model for Viral Hemorrhagic Fever.
Salvato MS, Lukashevich IS, Yang Y, Medina-Moreno S, Djavani M, Bryant J, Rodas JD, Zapata JC
Methods Mol Biol 2018;1604:279-290. doi: 10.1007/978-1-4939-6981-4_22. PMID: 28986843

Clinical prediction guides

Platinum-Based Chemotherapy Attenuates the Effector Response of CD8 T Cells to Concomitant PD-1 Blockade.
Mariniello A, Nasti TH, Chang DY, Hashimoto M, Malik S, McManus DT, Lee J, McGuire DJ, Cardenas MA, Umana P, Nicolini V, Antia R, Saha A, Buchwald Z, Kissick H, Ghorani E, Novello S, Sangiolo D, Scagliotti GV, Ramalingam SS, Ahmed R
Clin Cancer Res 2024 May 1;30(9):1833-1845. doi: 10.1158/1078-0432.CCR-23-1316. PMID: 37992307Free PMC Article
PD-1 combination therapy with IL-2 modifies CD8(+) T cell exhaustion program.
Hashimoto M, Araki K, Cardenas MA, Li P, Jadhav RR, Kissick HT, Hudson WH, McGuire DJ, Obeng RC, Wieland A, Lee J, McManus DT, Ross JL, Im SJ, Lee J, Lin JX, Hu B, West EE, Scharer CD, Freeman GJ, Sharpe AH, Ramalingam SS, Pellerin A, Teichgräber V, Greenleaf WJ, Klein C, Goronzy JJ, Umaña P, Leonard WJ, Smith KA, Ahmed R
Nature 2022 Oct;610(7930):173-181. Epub 2022 Sep 28 doi: 10.1038/s41586-022-05257-0. PMID: 36171288Free PMC Article
A Primate Model for Viral Hemorrhagic Fever.
Salvato MS, Lukashevich IS, Yang Y, Medina-Moreno S, Djavani M, Bryant J, Rodas JD, Zapata JC
Methods Mol Biol 2018;1604:279-290. doi: 10.1007/978-1-4939-6981-4_22. PMID: 28986843
Interleukin-12.
Brunda MJ
J Leukoc Biol 1994 Feb;55(2):280-8. doi: 10.1002/jlb.55.2.280. PMID: 7905508
Zoonoses.
Goscienski PJ
Pediatr Infect Dis 1983 Jan-Feb;2(1):69-81. doi: 10.1097/00006454-198301000-00018. PMID: 6340080

Recent systematic reviews

Maternal environmental risk factors for congenital hydrocephalus: a systematic review.
Kalyvas AV, Kalamatianos T, Pantazi M, Lianos GD, Stranjalis G, Alexiou GA
Neurosurg Focus 2016 Nov;41(5):E3. doi: 10.3171/2016.8.FOCUS16280. PMID: 27798989
Zoonotic and Vector-Borne Infections Among Urban Homeless and Marginalized People in the United States and Europe, 1990-2014.
Leibler JH, Zakhour CM, Gadhoke P, Gaeta JM
Vector Borne Zoonotic Dis 2016 Jul;16(7):435-44. Epub 2016 May 9 doi: 10.1089/vbz.2015.1863. PMID: 27159039
Viral infections in workers in hospital and research laboratory settings: a comparative review of infection modes and respective biosafety aspects.
Pedrosa PB, Cardoso TA
Int J Infect Dis 2011 Jun;15(6):e366-76. Epub 2011 Apr 14 doi: 10.1016/j.ijid.2011.03.005. PMID: 21497126Free PMC Article

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