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Kell blood group system(KEL)

MedGen UID:
7196
•Concept ID:
C0022546
•
Classification
Synonyms: BLOOD GROUP--KELL-CELLANO SYSTEM; K(0); KEL; Ko
SNOMED CT: Kell blood group system (115686000); ISBT system KEL (115686000); ISBT system 006 (115686000)
 
Gene (location): KEL (7q34)
 
OMIM®: 110900

Definition

Multiple erythrocytic antigens that comprise at least three pairs of alternates and amorphs, determined by one complex gene or possibly several genes at closely linked loci. The system is important in transfusion reactions. Its expression involves the X-chromosome. [from MeSH]

Professional guidelines

PubMed

Predicting anti-Kell-mediated hemolytic disease of the fetus and newborn: diagnostic accuracy of laboratory management.
Slootweg YM, Lindenburg IT, Koelewijn JM, Van Kamp IL, Oepkes D, De Haas M
Am J Obstet Gynecol 2018 Oct;219(4):393.e1-393.e8. Epub 2018 Jul 29 doi: 10.1016/j.ajog.2018.07.020. PMID: 30063902
Fetal anaemia: diagnosis and management.
Brennand J, Cameron A
Best Pract Res Clin Obstet Gynaecol 2008 Feb;22(1):15-29. Epub 2007 Oct 1 doi: 10.1016/j.bpobgyn.2007.08.005. PMID: 17904904
Prenatal diagnosis of Kell blood group genotypes: KEL1 and KEL2.
Lee S, Bennett PR, Overton T, Warwick R, Wu X, Redman CM
Am J Obstet Gynecol 1996 Aug;175(2):455-9. doi: 10.1016/s0002-9378(96)70161-8. PMID: 8765268

Recent systematic reviews

Standard Compared With Extended Red Blood Cell Antigen Matching for Prevention of Subsequent Hemolytic Disease of the Fetus and Newborn: A Systematic Review.
Sugrue RP, Olsen J, Abi Antoun ME, Skalla LA, Cate J, James AH, Stonehill A, Watkins V, Telen MJ, Federspiel JJ
Obstet Gynecol 2024 Oct 1;144(4):444-453. Epub 2024 Aug 8 doi: 10.1097/AOG.0000000000005701. PMID: 39116441Free PMC Article

Supplemental Content

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    Related information

    • ClinVar
      Related medical variations
    • Gene
      Related information in NCBI Gene
    • GTR
      Related information in GTR
    • GTR(Clinical)
      Clinical tests in GTR
    • MeSH
      Related Medical Subject Headings
    • OMIM
      Related records in OMIM
    • OMIM(Genes)
      OMIM records containing genes associated with phenotypes registered in MedGen
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

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