U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Hyperesthesia

MedGen UID:
9361
Concept ID:
C0020453
Sign or Symptom
Synonyms: Hyperesthesias; Hyperesthetic Sensation; Hyperesthetic Sensations; Oxyesthesia; Oxyesthesias; Sensation, Hyperesthetic; Sensations, Hyperesthetic
SNOMED CT: Hyperesthesia (14151009); Hyperesthesia (increased sensitivity) (14151009); Heightened sensation (14151009); Increased sensitivity - sensation (14151009); Hypersensitivity - sensation (14151009); Heightened sensation of skin (14151009)
 
HPO: HP:0100963

Definition

Increased sensitivity to stimulation, excluding the special senses, which may refer to various modes of cutaneous sensibility including touch and thermal sensation without pain, as well as to pain. [from HPO]

Term Hierarchy

Professional guidelines

PubMed

Labib A, Burke O, Nichols A, Maderal AD
J Am Acad Dermatol 2023 Dec;89(6):1192-1200. Epub 2023 Jul 28 doi: 10.1016/j.jaad.2023.06.063. PMID: 37517675
Yaksh TL, Fisher CJ, Hockman TM, Wiese AJ
Curr Neuropharmacol 2017;15(2):232-259. doi: 10.2174/1570159x14666160307145542. PMID: 26861470Free PMC Article
Hovaguimian A, Gibbons CH
Curr Pain Headache Rep 2011 Jun;15(3):193-200. doi: 10.1007/s11916-011-0181-7. PMID: 21286866Free PMC Article

Recent clinical studies

Etiology

Usui N, Kobayashi H, Shimada S
Int J Mol Sci 2023 Mar 13;24(6) doi: 10.3390/ijms24065487. PMID: 36982559Free PMC Article
Agarwal N, Aroor S, Saini P, Gupta A, Kaur N
Surg Infect (Larchmt) 2016 Oct;17(5):615-21. Epub 2016 Jul 27 doi: 10.1089/sur.2015.191. PMID: 27463090
Deiteren A, de Wit A, van der Linden L, De Man JG, Pelckmans PA, De Winter BY
Acta Gastroenterol Belg 2016 Mar;79(1):29-38. PMID: 26852761
Rolke R, Baron R, Maier C, Tölle TR, Treede -DR, Beyer A, Binder A, Birbaumer N, Birklein F, Bötefür IC, Braune S, Flor H, Huge V, Klug R, Landwehrmeyer GB, Magerl W, Maihöfner C, Rolko C, Schaub C, Scherens A, Sprenger T, Valet M, Wasserka B
Pain 2006 Aug;123(3):231-243. Epub 2006 May 11 doi: 10.1016/j.pain.2006.01.041. PMID: 16697110
Thompson TP, Pearce J, Chang G, Madamba J
Spine (Phila Pa 1976) 2004 Aug 15;29(16):E353-6. doi: 10.1097/01.brs.0000134689.84162.e7. PMID: 15303045

Diagnosis

Mahajan R, Kulkarni R, Stoopler ET
Spec Care Dentist 2022 Nov;42(6):555-564. Epub 2022 May 23 doi: 10.1111/scd.12726. PMID: 35605234
Šitum M, Kolić M, Franceschi N, Pećina M
Acta Clin Croat 2018 Dec;57(4):721-725. doi: 10.20471/acc.2018.57.04.14. PMID: 31168209Free PMC Article
Schwartz DP, Robbins MS, Grosberg BM
Curr Pain Headache Rep 2013 Jun;17(6):340. doi: 10.1007/s11916-013-0340-0. PMID: 23616207
Peñarrocha M, Cervelló MA, Martí E, Bagán JV
Oral Dis 2007 Mar;13(2):141-50. doi: 10.1111/j.1601-0825.2006.01356.x. PMID: 17305614
Rolke R, Baron R, Maier C, Tölle TR, Treede -DR, Beyer A, Binder A, Birbaumer N, Birklein F, Bötefür IC, Braune S, Flor H, Huge V, Klug R, Landwehrmeyer GB, Magerl W, Maihöfner C, Rolko C, Schaub C, Scherens A, Sprenger T, Valet M, Wasserka B
Pain 2006 Aug;123(3):231-243. Epub 2006 May 11 doi: 10.1016/j.pain.2006.01.041. PMID: 16697110

Therapy

Fujita Y, Murakami T, Nakamura A
Int J Mol Sci 2021 Feb 25;22(5) doi: 10.3390/ijms22052301. PMID: 33669048Free PMC Article
Schwartz DP, Robbins MS, Grosberg BM
Curr Pain Headache Rep 2013 Jun;17(6):340. doi: 10.1007/s11916-013-0340-0. PMID: 23616207
Hovaguimian A, Gibbons CH
Curr Pain Headache Rep 2011 Jun;15(3):193-200. doi: 10.1007/s11916-011-0181-7. PMID: 21286866Free PMC Article
Graff-Radford SB, Solberg WK
J Craniomandib Disord 1992 Fall;6(4):260-5. PMID: 1298761
Saddique A, Peterson CD
Vet Hum Toxicol 1983 Feb;25(1):16-22. PMID: 6338655

Prognosis

Lu YY, Qin H, Lu CC, Wu MK, Zhang CL, Wu CH
Postgrad Med J 2022 Jun;98(1160):450-455. Epub 2021 Feb 4 doi: 10.1136/postgradmedj-2020-139550. PMID: 33541932Free PMC Article
Uddin Z, MacDermid JC
Pain Med 2016 Sep;17(9):1694-703. Epub 2016 Feb 18 doi: 10.1093/pm/pnv105. PMID: 26893116
Boogaard S, Heymans MW, de Vet HC, Peters ML, Loer SA, Zuurmond WW, Perez RS
Pain Physician 2015 Sep-Oct;18(5):433-57. PMID: 26431122
Atalay NS, Ercidogan O, Akkaya N, Sahin F
Pain Physician 2014 Mar-Apr;17(2):179-85. PMID: 24658479
Latronico N, Shehu I, Seghelini E
Curr Opin Crit Care 2005 Aug;11(4):381-90. doi: 10.1097/01.ccx.0000168530.30702.3e. PMID: 16015120

Clinical prediction guides

Baek SK, Shin SW, Koh SJ, Kim JH, Kim HJ, Shim BY, Kang SY, Bae SB, Yun HJ, Sym SJ, Han HS, Gil HY
PLoS One 2021;16(8):e0252781. Epub 2021 Aug 17 doi: 10.1371/journal.pone.0252781. PMID: 34403429Free PMC Article
Agarwal N, Aroor S, Saini P, Gupta A, Kaur N
Surg Infect (Larchmt) 2016 Oct;17(5):615-21. Epub 2016 Jul 27 doi: 10.1089/sur.2015.191. PMID: 27463090
Uddin Z, MacDermid JC
Pain Med 2016 Sep;17(9):1694-703. Epub 2016 Feb 18 doi: 10.1093/pm/pnv105. PMID: 26893116
Boogaard S, Heymans MW, de Vet HC, Peters ML, Loer SA, Zuurmond WW, Perez RS
Pain Physician 2015 Sep-Oct;18(5):433-57. PMID: 26431122
Rolke R, Baron R, Maier C, Tölle TR, Treede -DR, Beyer A, Binder A, Birbaumer N, Birklein F, Bötefür IC, Braune S, Flor H, Huge V, Klug R, Landwehrmeyer GB, Magerl W, Maihöfner C, Rolko C, Schaub C, Scherens A, Sprenger T, Valet M, Wasserka B
Pain 2006 Aug;123(3):231-243. Epub 2006 May 11 doi: 10.1016/j.pain.2006.01.041. PMID: 16697110

Recent systematic reviews

Bruin LL, Hundepool CA, Duraku LS, Mureau MAM, Zuidam JM
J Plast Reconstr Aesthet Surg 2022 Jan;75(1):1-9. Epub 2021 Oct 8 doi: 10.1016/j.bjps.2021.09.028. PMID: 34736849
Addar A, Marwan Y, Algarni N, Algarni N, Berry GK, Benaroch T
Foot (Edinb) 2021 Dec;49:101864. Epub 2021 Sep 22 doi: 10.1016/j.foot.2021.101864. PMID: 34597922
Boogaard S, Heymans MW, de Vet HC, Peters ML, Loer SA, Zuurmond WW, Perez RS
Pain Physician 2015 Sep-Oct;18(5):433-57. PMID: 26431122
Ducic I, Zakaria HM, Felder JM 3rd, Fantus S
Aesthet Surg J 2014 Aug;34(6):841-56. Epub 2014 Aug 1 doi: 10.1177/1090820X14536726. PMID: 24951626
Andrews JC
Obstet Gynecol Surv 2011 May;66(5):299-315. doi: 10.1097/OGX.0b013e3182277fb7. PMID: 21794194

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...