U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Granuloma, Respiratory Tract

MedGen UID:
6675
•Concept ID:
C0018200
•
Disease or Syndrome
Synonyms: Granuloma, Respiratory System; Respiratory System Granuloma; Respiratory System Granulomas; Respiratory Tract Granuloma; Respiratory Tract Granulomas

Definition

Granulomatous disorders affecting one or more sites in the respiratory tract. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGranuloma, Respiratory Tract

Professional guidelines

PubMed

Diagnosis and Treatment of Benign Pediatric Lesions.
Hron TA, Kavanagh KR, Murray N
Otolaryngol Clin North Am 2019 Aug;52(4):657-668. Epub 2019 May 11 doi: 10.1016/j.otc.2019.03.010. PMID: 31088693
Management of Bronchial Complications After Lung Transplantation and Sequelae.
Varela A, Hoyos L, Romero A, Campo-Cañaveral JL, Crowley S
Thorac Surg Clin 2018 Aug;28(3):365-375. doi: 10.1016/j.thorsurg.2018.04.006. PMID: 30054074
Treatment of post-intubation laryngeal granulomas: systematic review and proportional meta-analysis.
Rimoli CF, Martins RHG, Catâneo DC, Imamura R, Catâneo AJM
Braz J Otorhinolaryngol 2018 Nov-Dec;84(6):781-789. Epub 2018 Apr 14 doi: 10.1016/j.bjorl.2018.03.003. PMID: 29699879Free PMC Article

Recent clinical studies

Etiology

Managing Granulomatous-Lymphocytic Interstitial Lung Disease in Common Variable Immunodeficiency Disorders: e-GLILDnet International Clinicians Survey.
van de Ven AAJM, Alfaro TM, Robinson A, Baumann U, Bergeron A, Burns SO, Condliffe AM, Fevang B, Gennery AR, Haerynck F, Jacob J, Jolles S, Malphettes M, Meignin V, Milota T, van Montfrans J, Prasse A, Quinti I, Renzoni E, Stolz D, Warnatz K, Hurst JR
Front Immunol 2020;11:606333. Epub 2020 Nov 26 doi: 10.3389/fimmu.2020.606333. PMID: 33324422Free PMC Article
The End of the Binary Era: Revisiting the Spectrum of Tuberculosis.
Lin PL, Flynn JL
J Immunol 2018 Nov 1;201(9):2541-2548. doi: 10.4049/jimmunol.1800993. PMID: 30348659Free PMC Article
Differential diagnosis of granulomatous lung disease: clues and pitfalls: Number 4 in the Series "Pathology for the clinician" Edited by Peter Dorfmüller and Alberto Cavazza.
Ohshimo S, Guzman J, Costabel U, Bonella F
Eur Respir Rev 2017 Sep 30;26(145) Epub 2017 Aug 9 doi: 10.1183/16000617.0012-2017. PMID: 28794143Free PMC Article
Lung transplantation in sarcoidosis.
Shah L
Semin Respir Crit Care Med 2007 Feb;28(1):134-40. doi: 10.1055/s-2007-970339. PMID: 17330198
Genetics of sarcoidosis.
Iannuzzi MC
Semin Respir Crit Care Med 2007 Feb;28(1):15-21. doi: 10.1055/s-2007-970330. PMID: 17330189

Diagnosis

Granulomatous Lung Diseases: A Practical Approach and Review of Common Entities.
Chan JCK, Boland JM
Surg Pathol Clin 2024 Jun;17(2):173-192. Epub 2023 Dec 16 doi: 10.1016/j.path.2023.11.004. PMID: 38692803
Pulmonary Hyalinizing Granuloma.
Karakurt G, Duger M
Arch Bronconeumol 2022 Dec;58(12):821-822. Epub 2022 Jul 21 doi: 10.1016/j.arbres.2022.07.009. PMID: 35914957
Pulmonary sarcoidosis.
Lynch JP 3rd, Ma YL, Koss MN, White ES
Semin Respir Crit Care Med 2007 Feb;28(1):53-74. doi: 10.1055/s-2007-970333. PMID: 17330192
Pathology of sarcoidosis.
Rosen Y
Semin Respir Crit Care Med 2007 Feb;28(1):36-52. doi: 10.1055/s-2007-970332. PMID: 17330191
Chronic hypersensitivity pneumonitis.
Churg A, Muller NL, Flint J, Wright JL
Am J Surg Pathol 2006 Feb;30(2):201-8. doi: 10.1097/01.pas.0000184806.38037.3c. PMID: 16434894

Therapy

Stimulants and the lung : review of literature.
Tseng W, Sutter ME, Albertson TE
Clin Rev Allergy Immunol 2014 Feb;46(1):82-100. doi: 10.1007/s12016-013-8376-9. PMID: 23760760
Pulmonary affectation of vasculitis.
Martín-Suñé N, Ríos-Blanco JJ
Arch Bronconeumol 2012 Nov;48(11):410-8. Epub 2012 Jun 6 doi: 10.1016/j.arbres.2012.04.007. PMID: 22682604
Pulmonary sarcoidosis.
Lynch JP 3rd, Ma YL, Koss MN, White ES
Semin Respir Crit Care Med 2007 Feb;28(1):53-74. doi: 10.1055/s-2007-970333. PMID: 17330192
Chronic hypersensitivity pneumonitis.
Churg A, Muller NL, Flint J, Wright JL
Am J Surg Pathol 2006 Feb;30(2):201-8. doi: 10.1097/01.pas.0000184806.38037.3c. PMID: 16434894
Interferon-induced granulomatous lung disease.
Marzouk K, Saleh S, Kannass M, Sharma OP
Curr Opin Pulm Med 2004 Sep;10(5):435-40. doi: 10.1097/01.mcp.0000134400.88832.9c. PMID: 15316444

Prognosis

Current Sarcoidosis Models and the Importance of Focusing on the Granuloma.
Locke LW, Schlesinger LS, Crouser ED
Front Immunol 2020;11:1719. Epub 2020 Aug 4 doi: 10.3389/fimmu.2020.01719. PMID: 32849608Free PMC Article
Pulmonary affectation of vasculitis.
Martín-Suñé N, Ríos-Blanco JJ
Arch Bronconeumol 2012 Nov;48(11):410-8. Epub 2012 Jun 6 doi: 10.1016/j.arbres.2012.04.007. PMID: 22682604
Lung transplantation in sarcoidosis.
Shah L
Semin Respir Crit Care Med 2007 Feb;28(1):134-40. doi: 10.1055/s-2007-970339. PMID: 17330198
Pulmonary sarcoidosis.
Lynch JP 3rd, Ma YL, Koss MN, White ES
Semin Respir Crit Care Med 2007 Feb;28(1):53-74. doi: 10.1055/s-2007-970333. PMID: 17330192
Genetics of sarcoidosis.
Iannuzzi MC
Semin Respir Crit Care Med 2007 Feb;28(1):15-21. doi: 10.1055/s-2007-970330. PMID: 17330189

Clinical prediction guides

A computational model tracks whole-lung Mycobacterium tuberculosis infection and predicts factors that inhibit dissemination.
Wessler T, Joslyn LR, Borish HJ, Gideon HP, Flynn JL, Kirschner DE, Linderman JJ
PLoS Comput Biol 2020 May;16(5):e1007280. Epub 2020 May 20 doi: 10.1371/journal.pcbi.1007280. PMID: 32433646Free PMC Article
Immunological roulette: Luck or something more? Considering the connections between host and environment in TB.
Pearl JE, Das M, Cooper AM
Cell Mol Immunol 2018 Mar;15(3):226-232. Epub 2018 Jan 29 doi: 10.1038/cmi.2017.145. PMID: 29375129Free PMC Article
Differential diagnosis of granulomatous lung disease: clues and pitfalls: Number 4 in the Series "Pathology for the clinician" Edited by Peter Dorfmüller and Alberto Cavazza.
Ohshimo S, Guzman J, Costabel U, Bonella F
Eur Respir Rev 2017 Sep 30;26(145) Epub 2017 Aug 9 doi: 10.1183/16000617.0012-2017. PMID: 28794143Free PMC Article
A hybrid multi-compartment model of granuloma formation and T cell priming in tuberculosis.
Marino S, El-Kebir M, Kirschner D
J Theor Biol 2011 Jul 7;280(1):50-62. Epub 2011 Apr 1 doi: 10.1016/j.jtbi.2011.03.022. PMID: 21443879Free PMC Article
Lung transplantation in sarcoidosis.
Shah L
Semin Respir Crit Care Med 2007 Feb;28(1):134-40. doi: 10.1055/s-2007-970339. PMID: 17330198

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...