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Paroxysmal dyspnea

MedGen UID:
41682
•Concept ID:
C0013405
•
Disease or Syndrome
Synonyms: Dyspnea, Paroxysmal; Paroxysmal Dyspnea
SNOMED CT: Paroxysmal dyspnea (59265000)
 
HPO: HP:0012763

Definition

A sudden attack of dyspnea that occurs while the affected person is at rest. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVParoxysmal dyspnea

Professional guidelines

PubMed

THE DIAGNOSIS AND TREATMENT OF ASTHMA IN THE ELDERLY.
TAUB SJ
Geriatrics 1964 Apr;19:235-9. PMID: 14141802
The management of three cardiovascular emergencies; shock, paroxysmal dyspnea and refractory congestive failure.
LEVINE HD
Harofe Haivri Heb Med J 1958;1:208-18. PMID: 13548724
The differential diagnosis between cardiac and bronchial asthma.
GELFAND M
Int Rec Med Gen Pract Clin 1953 Oct;166(10):420-4. PMID: 13108359

Recent clinical studies

Etiology

Paroxysmal dyspnea in Parkinson's disease: Respiratory dyskinesias and autonomic hyperventilation are not the same.
Friedman JH
Parkinsonism Relat Disord 2021 Aug;89:197-198. Epub 2021 Jul 9 doi: 10.1016/j.parkreldis.2021.07.008. PMID: 34266744
Prevalence of Febrile Seizures, Epilepsy, and Other Paroxysmal Attacks in a Swedish Cohort of 4-Year-Old Children.
Nilsson G, Fernell E, Arvidsson T, Neville B, Olsson I, Gillberg C
Neuropediatrics 2016 Dec;47(6):368-373. Epub 2016 Aug 14 doi: 10.1055/s-0036-1586731. PMID: 27522228
Sinus of Valsalva aneurysm with rupture. Case report and literature review.
Galicia-Tornell MM, Marín-Solís B, Mercado-Astorga O, Espinoza-Anguiano S, Martínez-Martínez M, Villalpando-Mendoza E
Cir Cir 2009 Nov-Dec;77(6):441-5. PMID: 20433789
Value of orthopnea, paroxysmal nocturnal dyspnea, and medications in prospective population studies of incident heart failure.
Ekundayo OJ, Howard VJ, Safford MM, McClure LA, Arnett D, Allman RM, Howard G, Ahmed A
Am J Cardiol 2009 Jul 15;104(2):259-64. Epub 2009 May 14 doi: 10.1016/j.amjcard.2009.03.025. PMID: 19576357Free PMC Article
Asthma in the elderly.
Lee HY, Stretton TB
Br Med J 1972 Oct 14;4(5832):93-5. doi: 10.1136/bmj.4.5832.93. PMID: 5077475Free PMC Article

Diagnosis

Asthma and COPD: Similarities and Differences in the Pathophysiology, Diagnosis and Therapy.
Yayan J, Rasche K
Adv Exp Med Biol 2016;910:31-8. doi: 10.1007/5584_2015_206. PMID: 26820733
Chronic obstructive pulmonary disease in heart failure: accurate diagnosis and treatment.
Güder G, Brenner S, Störk S, Hoes A, Rutten FH
Eur J Heart Fail 2014 Dec;16(12):1273-82. Epub 2014 Oct 27 doi: 10.1002/ejhf.183. PMID: 25345927
Diagnosis of elderly patients with heart failure.
Manzano L, Escobar C, Cleland JG, Flather M
Eur J Heart Fail 2012 Oct;14(10):1097-103. Epub 2012 Jul 6 doi: 10.1093/eurjhf/hfs109. PMID: 22771845
Value of orthopnea, paroxysmal nocturnal dyspnea, and medications in prospective population studies of incident heart failure.
Ekundayo OJ, Howard VJ, Safford MM, McClure LA, Arnett D, Allman RM, Howard G, Ahmed A
Am J Cardiol 2009 Jul 15;104(2):259-64. Epub 2009 May 14 doi: 10.1016/j.amjcard.2009.03.025. PMID: 19576357Free PMC Article
Asthma in the elderly.
Lee HY, Stretton TB
Br Med J 1972 Oct 14;4(5832):93-5. doi: 10.1136/bmj.4.5832.93. PMID: 5077475Free PMC Article

Therapy

Massive adrenocortical carcinoma presenting as peripheral edema: a case report.
Goodkin DA
J Med Case Rep 2022 Jun 20;16(1):249. doi: 10.1186/s13256-022-03397-5. PMID: 35725572Free PMC Article
Asthma and COPD: Similarities and Differences in the Pathophysiology, Diagnosis and Therapy.
Yayan J, Rasche K
Adv Exp Med Biol 2016;910:31-8. doi: 10.1007/5584_2015_206. PMID: 26820733
Chronic obstructive pulmonary disease in heart failure: accurate diagnosis and treatment.
Güder G, Brenner S, Störk S, Hoes A, Rutten FH
Eur J Heart Fail 2014 Dec;16(12):1273-82. Epub 2014 Oct 27 doi: 10.1002/ejhf.183. PMID: 25345927
Nebulized morphine for paroxysmal cough and dyspnea in a nursing home resident with metastatic cancer.
Stein WM, Min YK
Am J Hosp Palliat Care 1997 Mar-Apr;14(2):52-6. doi: 10.1177/104990919701400201. PMID: 9295402
Asthma in the elderly.
Lee HY, Stretton TB
Br Med J 1972 Oct 14;4(5832):93-5. doi: 10.1136/bmj.4.5832.93. PMID: 5077475Free PMC Article

Prognosis

Massive adrenocortical carcinoma presenting as peripheral edema: a case report.
Goodkin DA
J Med Case Rep 2022 Jun 20;16(1):249. doi: 10.1186/s13256-022-03397-5. PMID: 35725572Free PMC Article
Prognostic Significance of Longitudinal Clinical Congestion Pattern in Chronic Heart Failure: Insights From TIME-CHF Trial.
Simonavičius J, Sanders van-Wijk S, Rickenbacher P, Maeder MT, Pfister O, Kaufmann BA, Pfisterer M, Čelutkienė J, Puronaitė R, Knackstedt C, van Empel V, Brunner-La Rocca HP
Am J Med 2019 Sep;132(9):e679-e692. Epub 2019 Apr 30 doi: 10.1016/j.amjmed.2019.04.010. PMID: 31051151
A 58-Year-Old Man With Position-Dependent Nocturnal Dyspnea.
Schertel A, Horvath CM, Pichler Hefti J, Aubert JD, Brill AK
Chest 2017 Aug;152(2):e51-e55. doi: 10.1016/j.chest.2017.03.014. PMID: 28797401
Value of orthopnea, paroxysmal nocturnal dyspnea, and medications in prospective population studies of incident heart failure.
Ekundayo OJ, Howard VJ, Safford MM, McClure LA, Arnett D, Allman RM, Howard G, Ahmed A
Am J Cardiol 2009 Jul 15;104(2):259-64. Epub 2009 May 14 doi: 10.1016/j.amjcard.2009.03.025. PMID: 19576357Free PMC Article
Chronic pulmonary thromboembolism.
Tartulier M, Boutarin J, Ritz B
G Ital Cardiol 1984;14 Suppl 1:13-21. PMID: 6534760

Clinical prediction guides

Prognostic Significance of Longitudinal Clinical Congestion Pattern in Chronic Heart Failure: Insights From TIME-CHF Trial.
Simonavičius J, Sanders van-Wijk S, Rickenbacher P, Maeder MT, Pfister O, Kaufmann BA, Pfisterer M, Čelutkienė J, Puronaitė R, Knackstedt C, van Empel V, Brunner-La Rocca HP
Am J Med 2019 Sep;132(9):e679-e692. Epub 2019 Apr 30 doi: 10.1016/j.amjmed.2019.04.010. PMID: 31051151
A 58-Year-Old Man With Position-Dependent Nocturnal Dyspnea.
Schertel A, Horvath CM, Pichler Hefti J, Aubert JD, Brill AK
Chest 2017 Aug;152(2):e51-e55. doi: 10.1016/j.chest.2017.03.014. PMID: 28797401
Value of orthopnea, paroxysmal nocturnal dyspnea, and medications in prospective population studies of incident heart failure.
Ekundayo OJ, Howard VJ, Safford MM, McClure LA, Arnett D, Allman RM, Howard G, Ahmed A
Am J Cardiol 2009 Jul 15;104(2):259-64. Epub 2009 May 14 doi: 10.1016/j.amjcard.2009.03.025. PMID: 19576357Free PMC Article
Prevalence, clinical features, and acute course of atypical myocardial infarction.
Lusiani L, Perrone A, Pesavento R, Conte G
Angiology 1994 Jan;45(1):49-55. doi: 10.1177/000331979404500107. PMID: 8285384
Dyspnea: the heart or the lungs? Differentiation at bedside by use of the simple Valsalva maneuver.
Zema MJ, Masters AP, Margouleff D
Chest 1984 Jan;85(1):59-64. doi: 10.1378/chest.85.1.59. PMID: 6690252

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