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Shigellosis

MedGen UID:
8513
•Concept ID:
C0013371
•
Disease or Syndrome
Synonyms: Dysenteries, Shigella; Dysentery, Shigella; Infection, Shigella; Infections, Shigella; Shigella Dysenteries; Shigella Dysentery; Shigella Infection; Shigella Infections
SNOMED CT: Shigella dysentery (36188001); Infection by Shigella (111817006); Infection caused by Shigella (111817006); Shigellosis (36188001); Shigella gastroenteritis (36188001); Japanese dysentery (36188001); Flexner's dysentery (36188001)
Modes of inheritance:
Not genetically inherited
MedGen UID:
988794
•Concept ID:
CN307044
•
Finding
Source: Orphanet
clinical entity without genetic inheritance.
See: This record
Not genetically inherited (Orphanet)
 
Monarch Initiative: MONDO:0019345
Orphanet: ORPHA810

Definition

Shigellosis is a bacterial infection leading to dysentery and is caused by <i>Shigella</i>, which are small, ubiquitous Gram-negative bacteria belonging to the enterobacteria family. There are four species: <i>S. dysenteriae</i>, <i>S. flexneri</i>, <i>S. boydii</i> and <i>S. sonnei</i>, all of which cause bacillary dysentery and are strictly limited to human hosts. [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVShigellosis
Follow this link to review classifications for Shigellosis in Orphanet.

Professional guidelines

PubMed

Acute diarrhea with blood: diagnosis and drug treatment.
da Cruz Gouveia MA, Lins MTC, da Silva GAP
J Pediatr (Rio J) 2020 Mar-Apr;96 Suppl 1(Suppl 1):20-28. Epub 2019 Oct 8 doi: 10.1016/j.jped.2019.08.006. PMID: 31604059Free PMC Article
Acute diarrhea: evidence-based management.
Brandt KG, Castro Antunes MM, Silva GA
J Pediatr (Rio J) 2015 Nov-Dec;91(6 Suppl 1):S36-43. Epub 2015 Sep 6 doi: 10.1016/j.jped.2015.06.002. PMID: 26351768
Treatment of shigellosis.
Park JW, Rogers PL
J Pediatr 1991 Nov;119(5):841. doi: 10.1016/s0022-3476(05)80318-x. PMID: 1941398

Recent clinical studies

Etiology

Pathogenicity and virulence of Shigella sonnei: A highly drug-resistant pathogen of increasing prevalence.
Matanza XM, Clements A
Virulence 2023 Dec;14(1):2280838. Epub 2023 Nov 23 doi: 10.1080/21505594.2023.2280838. PMID: 37994877Free PMC Article
Molecular Mechanisms of Shigella Pathogenesis; Recent Advances.
Pakbin B, Brück WM, Brück TB
Int J Mol Sci 2023 Jan 26;24(3) doi: 10.3390/ijms24032448. PMID: 36768771Free PMC Article
Natural Disasters and Cholera Outbreaks: Current Understanding and Future Outlook.
Jutla A, Khan R, Colwell R
Curr Environ Health Rep 2017 Mar;4(1):99-107. doi: 10.1007/s40572-017-0132-5. PMID: 28130661
Acute diarrhea.
Barr W, Smith A
Am Fam Physician 2014 Feb 1;89(3):180-9. PMID: 24506120
Haemolytic uraemic syndrome during shigellosis.
Butler T
Trans R Soc Trop Med Hyg 2012 Jul;106(7):395-9. Epub 2012 May 10 doi: 10.1016/j.trstmh.2012.04.001. PMID: 22579556

Diagnosis

Acute diarrhea with blood: diagnosis and drug treatment.
da Cruz Gouveia MA, Lins MTC, da Silva GAP
J Pediatr (Rio J) 2020 Mar-Apr;96 Suppl 1(Suppl 1):20-28. Epub 2019 Oct 8 doi: 10.1016/j.jped.2019.08.006. PMID: 31604059Free PMC Article
Shigellosis.
Kotloff KL, Riddle MS, Platts-Mills JA, Pavlinac P, Zaidi AKM
Lancet 2018 Feb 24;391(10122):801-812. Epub 2017 Dec 16 doi: 10.1016/S0140-6736(17)33296-8. PMID: 29254859
Shigellosis.
Burnett MW
J Spec Oper Med 2017 Winter;17(4):102-103. doi: 10.55460/2PLM-RQTR. PMID: 29256205
Traveler's myopericarditis.
Vieira NB, Rodriguez-Vera J, Grade MJ, Santos C
Eur J Intern Med 2008 Mar;19(2):146-7. Epub 2007 Oct 1 doi: 10.1016/j.ejim.2007.04.023. PMID: 18249314
Shigella.
DuPont HL
Infect Dis Clin North Am 1988 Sep;2(3):599-605. PMID: 3074117

Therapy

The evolution and international spread of extensively drug resistant Shigella sonnei.
Mason LCE, Greig DR, Cowley LA, Partridge SR, Martinez E, Blackwell GA, Chong CE, De Silva PM, Bengtsson RJ, Draper JL, Ginn AN, Sandaradura I, Sim EM, Iredell JR, Sintchenko V, Ingle DJ, Howden BP, Lefèvre S, Njamkepo E, Weill FX, Ceyssens PJ, Jenkins C, Baker KS
Nat Commun 2023 Apr 8;14(1):1983. doi: 10.1038/s41467-023-37672-w. PMID: 37031199Free PMC Article
Shigellosis.
Burnett MW
J Spec Oper Med 2017 Winter;17(4):102-103. doi: 10.55460/2PLM-RQTR. PMID: 29256205
Acute diarrhea: evidence-based management.
Brandt KG, Castro Antunes MM, Silva GA
J Pediatr (Rio J) 2015 Nov-Dec;91(6 Suppl 1):S36-43. Epub 2015 Sep 6 doi: 10.1016/j.jped.2015.06.002. PMID: 26351768
Treatment of drug-resistant Shigella infections.
Klontz KC, Singh N
Expert Rev Anti Infect Ther 2015 Jan;13(1):69-80. Epub 2014 Nov 17 doi: 10.1586/14787210.2015.983902. PMID: 25399653
Haemolytic uraemic syndrome during shigellosis.
Butler T
Trans R Soc Trop Med Hyg 2012 Jul;106(7):395-9. Epub 2012 May 10 doi: 10.1016/j.trstmh.2012.04.001. PMID: 22579556

Prognosis

Natural Disasters and Cholera Outbreaks: Current Understanding and Future Outlook.
Jutla A, Khan R, Colwell R
Curr Environ Health Rep 2017 Mar;4(1):99-107. doi: 10.1007/s40572-017-0132-5. PMID: 28130661
HIV-Related Opportunistic Infections Are Still Relevant in 2015.
Masur H
Top Antivir Med 2015 Aug-Sep;23(3):116-9. PMID: 26518395Free PMC Article
Acute diarrhea: evidence-based management.
Brandt KG, Castro Antunes MM, Silva GA
J Pediatr (Rio J) 2015 Nov-Dec;91(6 Suppl 1):S36-43. Epub 2015 Sep 6 doi: 10.1016/j.jped.2015.06.002. PMID: 26351768
The Shigella human challenge model.
Porter CK, Thura N, Ranallo RT, Riddle MS
Epidemiol Infect 2013 Feb;141(2):223-32. Epub 2012 Aug 21 doi: 10.1017/S0950268812001677. PMID: 22906296Free PMC Article
Traveler's diarrhea: clinical presentation and prognosis.
Katelaris PH, Farthing MJ
Chemotherapy 1995;41 Suppl 1:40-7. doi: 10.1159/000239396. PMID: 7671646

Clinical prediction guides

Pathogenicity and virulence of Shigella sonnei: A highly drug-resistant pathogen of increasing prevalence.
Matanza XM, Clements A
Virulence 2023 Dec;14(1):2280838. Epub 2023 Nov 23 doi: 10.1080/21505594.2023.2280838. PMID: 37994877Free PMC Article
The evolution and international spread of extensively drug resistant Shigella sonnei.
Mason LCE, Greig DR, Cowley LA, Partridge SR, Martinez E, Blackwell GA, Chong CE, De Silva PM, Bengtsson RJ, Draper JL, Ginn AN, Sandaradura I, Sim EM, Iredell JR, Sintchenko V, Ingle DJ, Howden BP, Lefèvre S, Njamkepo E, Weill FX, Ceyssens PJ, Jenkins C, Baker KS
Nat Commun 2023 Apr 8;14(1):1983. doi: 10.1038/s41467-023-37672-w. PMID: 37031199Free PMC Article
Shigella flexneri: an emerging pathogen.
Nisa I, Qasim M, Yasin N, Ullah R, Ali A
Folia Microbiol (Praha) 2020 Apr;65(2):275-291. Epub 2020 Feb 5 doi: 10.1007/s12223-020-00773-w. PMID: 32026288
Natural Disasters and Cholera Outbreaks: Current Understanding and Future Outlook.
Jutla A, Khan R, Colwell R
Curr Environ Health Rep 2017 Mar;4(1):99-107. doi: 10.1007/s40572-017-0132-5. PMID: 28130661
Doxycycline prophylaxis for shigellosis.
Ben-Yehuda O, Cohen D, Alkan M, Greenbaum A, Jelin N, Steinherz R
Arch Intern Med 1990 Jan;150(1):209-12. PMID: 2404480

Recent systematic reviews

A systematic review of neglected tropical diseases (NTDs) in Myanmar.
Swe MMM, Phyo AP, Cooper BS, White NJ, Smithuis F, Ashley EA
PLoS Negl Trop Dis 2023 Nov;17(11):e0011706. Epub 2023 Nov 1 doi: 10.1371/journal.pntd.0011706. PMID: 37910592Free PMC Article
Shigellosis in Southeast Asia: A systematic review and meta-analysis.
Muzembo BA, Kitahara K, Mitra D, Ohno A, Khatiwada J, Dutta S, Miyoshi SI
Travel Med Infect Dis 2023 Mar-Apr;52:102554. Epub 2023 Feb 16 doi: 10.1016/j.tmaid.2023.102554. PMID: 36792021
Associations between ambient temperature and enteric infections by pathogen: a systematic review and meta-analysis.
Chua PLC, Ng CFS, Tobias A, Seposo XT, Hashizume M
Lancet Planet Health 2022 Mar;6(3):e202-e218. doi: 10.1016/S2542-5196(22)00003-1. PMID: 35278387
The Shigella human challenge model.
Porter CK, Thura N, Ranallo RT, Riddle MS
Epidemiol Infect 2013 Feb;141(2):223-32. Epub 2012 Aug 21 doi: 10.1017/S0950268812001677. PMID: 22906296Free PMC Article
Causative species and serotypes of shigellosis in mainland China: systematic review and meta-analysis.
Chang Z, Lu S, Chen L, Jin Q, Yang J
PLoS One 2012;7(12):e52515. Epub 2012 Dec 20 doi: 10.1371/journal.pone.0052515. PMID: 23285073Free PMC Article

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