U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Dumping syndrome

MedGen UID:
8501
Concept ID:
C0013288
Disease or Syndrome
Synonyms: Dumping Syndrome; Dumping Syndromes; Syndrome, Dumping; Syndromes, Dumping
SNOMED CT: Dumping syndrome (80193009)
 
Monarch Initiative: MONDO:0001979

Definition

A disorder of the gastrointestinal tract. It is typically caused by the rapid emptying of undigested food from the stomach to the small intestine following gastroesophageal surgery but may be seen secondary to diabetes or the use of certain medications. Clinical signs may be seen 30-60 minutes after eating (early dumping): cramping, nausea, vomiting and diarrhea or they may be seen 1-3 hours later as a result of hyperinsulinemic hypoglycemia (late dumping): sweating, dizziness, confusion and heart palpitations. Untreated, the clinical course progresses to malnutrition and weight loss. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDumping syndrome

Professional guidelines

PubMed

Carrillo Lozano E, Osés Zárate V, Campos Del Portillo R
Endocrinol Diabetes Nutr (Engl Ed) 2021 Jun-Jul;68(6):428-438. Epub 2021 Oct 12 doi: 10.1016/j.endien.2020.09.005. PMID: 34742476
Scarpellini E, Arts J, Karamanolis G, Laurenius A, Siquini W, Suzuki H, Ukleja A, Van Beek A, Vanuytsel T, Bor S, Ceppa E, Di Lorenzo C, Emous M, Hammer H, Hellström P, Laville M, Lundell L, Masclee A, Ritz P, Tack J
Nat Rev Endocrinol 2020 Aug;16(8):448-466. Epub 2020 May 26 doi: 10.1038/s41574-020-0357-5. PMID: 32457534Free PMC Article
Malik S, Mitchell JE, Steffen K, Engel S, Wiisanen R, Garcia L, Malik SA
Obes Res Clin Pract 2016 Jan-Feb;10(1):1-14. Epub 2015 Oct 27 doi: 10.1016/j.orcp.2015.07.003. PMID: 26522879Free PMC Article

Recent clinical studies

Therapy

Della Pepa G, Vetrani C, Lupoli R, Massimino E, Lembo E, Riccardi G, Capaldo B
Crit Rev Food Sci Nutr 2022;62(12):3250-3263. Epub 2021 Jan 18 doi: 10.1080/10408398.2020.1864617. PMID: 33455416
Bettini S, Belligoli A, Fabris R, Busetto L
Rev Endocr Metab Disord 2020 Sep;21(3):297-306. doi: 10.1007/s11154-020-09571-8. PMID: 32734395Free PMC Article
Scarpellini E, Arts J, Karamanolis G, Laurenius A, Siquini W, Suzuki H, Ukleja A, Van Beek A, Vanuytsel T, Bor S, Ceppa E, Di Lorenzo C, Emous M, Hammer H, Hellström P, Laville M, Lundell L, Masclee A, Ritz P, Tack J
Nat Rev Endocrinol 2020 Aug;16(8):448-466. Epub 2020 May 26 doi: 10.1038/s41574-020-0357-5. PMID: 32457534Free PMC Article
van Beek AP, Emous M, Laville M, Tack J
Obes Rev 2017 Jan;18(1):68-85. Epub 2016 Oct 17 doi: 10.1111/obr.12467. PMID: 27749997
Malik S, Mitchell JE, Steffen K, Engel S, Wiisanen R, Garcia L, Malik SA
Obes Res Clin Pract 2016 Jan-Feb;10(1):1-14. Epub 2015 Oct 27 doi: 10.1016/j.orcp.2015.07.003. PMID: 26522879Free PMC Article

Prognosis

Yang JC, Zhang GX, Leng C, Chen G, Cheng Z, Du X
Obes Surg 2023 Nov;33(11):3510-3516. Epub 2023 Oct 7 doi: 10.1007/s11695-023-06863-1. PMID: 37804471
Bjørklund G, Semenova Y, Pivina L, Costea DO
Nutrition 2020 Oct;78:110831. Epub 2020 Apr 21 doi: 10.1016/j.nut.2020.110831. PMID: 32544850
Mancini MC
Arq Bras Endocrinol Metabol 2014 Dec;58(9):875-88. doi: 10.1590/0004-2730000003413. PMID: 25627042
Eagon JC, Miedema BW, Kelly KA
Surg Clin North Am 1992 Apr;72(2):445-65. doi: 10.1016/s0039-6109(16)45689-6. PMID: 1549803
van Heerden JA, Phillips SF, Adson MA, McIlrath DC
Am J Surg 1975 Jan;129(1):82-8. doi: 10.1016/0002-9610(75)90172-5. PMID: 1082249

Clinical prediction guides

Müller A, Efeler S, Laskowski NM, Pommnitz M, Mall JW, Meyer G, Wunder R, Köhler H, Hüttl TP, de Zwaan M
Obes Facts 2024;17(2):201-210. Epub 2024 Feb 6 doi: 10.1159/000536602. PMID: 38320543Free PMC Article
van Furth AM, de Heide LJM, Emous M, Veeger N, van Beek AP
Surg Obes Relat Dis 2021 Nov;17(11):1912-1918. Epub 2021 May 19 doi: 10.1016/j.soard.2021.05.020. PMID: 34144916
Straatman J, Wiegel J, van der Wielen N, Jansma EP, Cuesta MA, van der Peet DL
Dig Surg 2017;34(5):364-370. Epub 2017 Mar 18 doi: 10.1159/000454958. PMID: 28315875
Berg P, McCallum R
Dig Dis Sci 2016 Jan;61(1):11-8. Epub 2015 Sep 22 doi: 10.1007/s10620-015-3839-x. PMID: 26396002
Mancini SA, Angelo JL, Peckler Z, Philp FH, Farah KF
Am Surg 2015 Jul;81(7):738-46. PMID: 26140897

Recent systematic reviews

D'hoedt A, Vanuytsel T
Acta Gastroenterol Belg 2023 Jul-Sep;86(3):417-427. doi: 10.51821/86.3.11476. PMID: 37814558
Hong S, Park B, Noh H, Choi DJ
Integr Cancer Ther 2019 Jan-Dec;18:1534735419873404. doi: 10.1177/1534735419873404. PMID: 31549529Free PMC Article
Boshier PR, Huddy JR, Zaninotto G, Hanna GB
Dis Esophagus 2017 Jan 1;30(1):1-9. doi: 10.1111/dote.12488. PMID: 27859950
van Beek AP, Emous M, Laville M, Tack J
Obes Rev 2017 Jan;18(1):68-85. Epub 2016 Oct 17 doi: 10.1111/obr.12467. PMID: 27749997
Shoar S, Nguyen T, Ona MA, Reddy M, Anand S, Alkuwari MJ, Saber AA
Surg Obes Relat Dis 2016 Aug;12(7):1366-1372. Epub 2016 Feb 26 doi: 10.1016/j.soard.2016.02.023. PMID: 27260651

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...