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Dry eye syndrome

MedGen UID:
4411
Concept ID:
C0013238
Disease or Syndrome
Synonyms: Dry Eye Disease; Dry Eye Diseases; Dry Eye Syndrome; Dry Eye Syndromes
SNOMED CT: Dry eye syndrome (46152009)
 
Monarch Initiative: MONDO:0006733

Definition

A syndrome characterized by dryness of the cornea and conjunctiva. It is usually caused by a deficiency in tear production. Symptoms include a feeling of burning eyes and a possible foreign body presence in the eye. [from NCI]

Professional guidelines

PubMed

Amescua G, Ahmad S, Cheung AY, Choi DS, Jhanji V, Lin A, Mian SI, Rhee MK, Viriya ET, Mah FS, Varu DM; American Academy of Ophthalmology Preferred Practice Pattern Cornea/External Disease Panel
Ophthalmology 2024 Apr;131(4):P1-P49. Epub 2024 Feb 12 doi: 10.1016/j.ophtha.2023.12.041. PMID: 38349301
Akpek EK, Amescua G, Farid M, Garcia-Ferrer FJ, Lin A, Rhee MK, Varu DM, Musch DC, Dunn SP, Mah FS; American Academy of Ophthalmology Preferred Practice Pattern Cornea and External Disease Panel
Ophthalmology 2019 Jan;126(1):P286-P334. Epub 2018 Oct 23 doi: 10.1016/j.ophtha.2018.10.023. PMID: 30366798
Rouen PA, White ML
Home Healthc Now 2018 Mar/Apr;36(2):74-83. doi: 10.1097/NHH.0000000000000652. PMID: 29498987

Recent clinical studies

Etiology

Rodrigues C, Carvalho F, Marques M
Aesthetic Plast Surg 2023 Oct;47(5):1870-1883. Epub 2023 Jul 10 doi: 10.1007/s00266-023-03436-6. PMID: 37430010Free PMC Article
Qian L, Wei W
PLoS One 2022;17(8):e0271267. Epub 2022 Aug 19 doi: 10.1371/journal.pone.0271267. PMID: 35984830Free PMC Article
Lee JM, Baek JS
Korean J Ophthalmol 2021 Oct;35(5):349-354. Epub 2021 Jul 8 doi: 10.3341/kjo.2021.0069. PMID: 34237206Free PMC Article
Rouen PA, White ML
Home Healthc Now 2018 Mar/Apr;36(2):74-83. doi: 10.1097/NHH.0000000000000652. PMID: 29498987
Ervin AM, Law A, Pucker AD
Cochrane Database Syst Rev 2017 Jun 26;6(6):CD006775. doi: 10.1002/14651858.CD006775.pub3. PMID: 28649802Free PMC Article

Diagnosis

Amescua G, Ahmad S, Cheung AY, Choi DS, Jhanji V, Lin A, Mian SI, Rhee MK, Viriya ET, Mah FS, Varu DM; American Academy of Ophthalmology Preferred Practice Pattern Cornea/External Disease Panel
Ophthalmology 2024 Apr;131(4):P1-P49. Epub 2024 Feb 12 doi: 10.1016/j.ophtha.2023.12.041. PMID: 38349301
Rolando M, Barabino S
Int J Mol Sci 2023 Jan 11;24(2) doi: 10.3390/ijms24021458. PMID: 36674972Free PMC Article
Akpek EK, Amescua G, Farid M, Garcia-Ferrer FJ, Lin A, Rhee MK, Varu DM, Musch DC, Dunn SP, Mah FS; American Academy of Ophthalmology Preferred Practice Pattern Cornea and External Disease Panel
Ophthalmology 2019 Jan;126(1):P286-P334. Epub 2018 Oct 23 doi: 10.1016/j.ophtha.2018.10.023. PMID: 30366798
Rouen PA, White ML
Home Healthc Now 2018 Mar/Apr;36(2):74-83. doi: 10.1097/NHH.0000000000000652. PMID: 29498987
Sullivan SD, Sarrel PM, Nelson LM
Fertil Steril 2016 Dec;106(7):1588-1599. doi: 10.1016/j.fertnstert.2016.09.046. PMID: 27912889Free PMC Article

Therapy

Rolando M, Barabino S
Int J Mol Sci 2023 Jan 11;24(2) doi: 10.3390/ijms24021458. PMID: 36674972Free PMC Article
Qian L, Wei W
PLoS One 2022;17(8):e0271267. Epub 2022 Aug 19 doi: 10.1371/journal.pone.0271267. PMID: 35984830Free PMC Article
de Paiva CS, Pflugfelder SC, Ng SM, Akpek EK
Cochrane Database Syst Rev 2019 Sep 13;9(9):CD010051. doi: 10.1002/14651858.CD010051.pub2. PMID: 31517988Free PMC Article
Akpek EK, Amescua G, Farid M, Garcia-Ferrer FJ, Lin A, Rhee MK, Varu DM, Musch DC, Dunn SP, Mah FS; American Academy of Ophthalmology Preferred Practice Pattern Cornea and External Disease Panel
Ophthalmology 2019 Jan;126(1):P286-P334. Epub 2018 Oct 23 doi: 10.1016/j.ophtha.2018.10.023. PMID: 30366798
Rouen PA, White ML
Home Healthc Now 2018 Mar/Apr;36(2):74-83. doi: 10.1097/NHH.0000000000000652. PMID: 29498987

Prognosis

Nowowiejska J, Ordon AJ, Baran A, Izdebska J, Woźniak B, Kaminski TW, Szaflik J, Flisiak I
J Eur Acad Dermatol Venereol 2024 Aug;38(8):1522-1530. Epub 2023 Dec 22 doi: 10.1111/jdv.19773. PMID: 38140772
Yin L, Zhang M, He T, Chen S
J Clin Lab Anal 2021 Jan;35(1):e23571. Epub 2020 Sep 16 doi: 10.1002/jcla.23571. PMID: 32935891Free PMC Article
Yoo TK, Oh E
Int Ophthalmol 2019 Nov;39(11):2611-2620. Epub 2019 May 7 doi: 10.1007/s10792-019-01110-y. PMID: 31065905
Rouen PA, White ML
Home Healthc Now 2018 Mar/Apr;36(2):74-83. doi: 10.1097/NHH.0000000000000652. PMID: 29498987
Raoof D, Pineda R
Semin Ophthalmol 2014 Sep-Nov;29(5-6):358-62. doi: 10.3109/08820538.2014.962663. PMID: 25325861

Clinical prediction guides

Yang YJ, Lee WY, Kim YJ, Hong YP
Int J Environ Res Public Health 2021 Mar 1;18(5) doi: 10.3390/ijerph18052383. PMID: 33804439Free PMC Article
Zdebik N, Zdebik A, Bogusławska J, Przeździecka-Dołyk J, Turno-Kręcicka A
Surv Ophthalmol 2021 Jan-Feb;66(1):132-137. Epub 2020 Jun 5 doi: 10.1016/j.survophthal.2020.05.006. PMID: 32512032
de Paiva CS, Pflugfelder SC, Ng SM, Akpek EK
Cochrane Database Syst Rev 2019 Sep 13;9(9):CD010051. doi: 10.1002/14651858.CD010051.pub2. PMID: 31517988Free PMC Article
Sadykov E, Studnička J, Hosák L, Siligardou MR, Elfurjani H, Hoikam JL, Kugananthan S, Petrovas A, Amjad T
Acta Medica (Hradec Kralove) 2019;62(2):45-51. doi: 10.14712/18059694.2019.104. PMID: 31362812
Ervin AM, Law A, Pucker AD
Cochrane Database Syst Rev 2017 Jun 26;6(6):CD006775. doi: 10.1002/14651858.CD006775.pub3. PMID: 28649802Free PMC Article

Recent systematic reviews

Rodrigues C, Carvalho F, Marques M
Aesthetic Plast Surg 2023 Oct;47(5):1870-1883. Epub 2023 Jul 10 doi: 10.1007/s00266-023-03436-6. PMID: 37430010Free PMC Article
Qian L, Wei W
PLoS One 2022;17(8):e0271267. Epub 2022 Aug 19 doi: 10.1371/journal.pone.0271267. PMID: 35984830Free PMC Article
Chan HN, Zhang XJ, Ling XT, Bui CH, Wang YM, Ip P, Chu WK, Chen LJ, Tham CC, Yam JC, Pang CP
Int J Mol Sci 2022 Apr 11;23(8) doi: 10.3390/ijms23084226. PMID: 35457041Free PMC Article
Brito-Zerón P, Retamozo S, Kostov B, Baldini C, Bootsma H, De Vita S, Dörner T, Gottenberg JE, Kruize AA, Mandl T, Ng WF, Seror R, Tzioufas AG, Vitali C, Bowman S, Mariette X, Ramos-Casals M
RMD Open 2019;5(2):e001064. Epub 2019 Oct 28 doi: 10.1136/rmdopen-2019-001064. PMID: 31749986Free PMC Article
de Paiva CS, Pflugfelder SC, Ng SM, Akpek EK
Cochrane Database Syst Rev 2019 Sep 13;9(9):CD010051. doi: 10.1002/14651858.CD010051.pub2. PMID: 31517988Free PMC Article

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