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Dizziness

MedGen UID:
4360
•Concept ID:
C0012833
•
Sign or Symptom
Synonym: Dizzyness
SNOMED CT: Dizziness (404640003); Dizzy (404640003)

Definition

A sensation of lightheadedness, unsteadiness, turning, spinning or rocking. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDizziness

Professional guidelines

PubMed

Vestibular Rehabilitation for Peripheral Vestibular Hypofunction: An Updated Clinical Practice Guideline From the Academy of Neurologic Physical Therapy of the American Physical Therapy Association.
Hall CD, Herdman SJ, Whitney SL, Anson ER, Carender WJ, Hoppes CW, Cass SP, Christy JB, Cohen HS, Fife TD, Furman JM, Shepard NT, Clendaniel RA, Dishman JD, Goebel JA, Meldrum D, Ryan C, Wallace RL, Woodward NJ
J Neurol Phys Ther 2022 Apr 1;46(2):118-177. doi: 10.1097/NPT.0000000000000382. PMID: 34864777Free PMC Article
Upper Gastrointestinal Bleeding in Adults: Evaluation and Management.
Wilkins T, Wheeler B, Carpenter M
Am Fam Physician 2020 Mar 1;101(5):294-300. PMID: 32109037
Clinical Practice Guideline: Benign Paroxysmal Positional Vertigo (Update).
Bhattacharyya N, Gubbels SP, Schwartz SR, Edlow JA, El-Kashlan H, Fife T, Holmberg JM, Mahoney K, Hollingsworth DB, Roberts R, Seidman MD, Steiner RW, Do BT, Voelker CC, Waguespack RW, Corrigan MD
Otolaryngol Head Neck Surg 2017 Mar;156(3_suppl):S1-S47. doi: 10.1177/0194599816689667. PMID: 28248609

Recent clinical studies

Etiology

Effects of vestibular rehabilitation therapy versus virtual reality on balance, dizziness, and gait in patients with subacute stroke: A randomized controlled trial.
Sana V, Ghous M, Kashif M, Albalwi A, Muneer R, Zia M
Medicine (Baltimore) 2023 Jun 16;102(24):e33203. doi: 10.1097/MD.0000000000033203. PMID: 37327306Free PMC Article
Vascular vertigo and dizziness: Diagnostic criteria.
Kim JS, Newman-Toker DE, Kerber KA, Jahn K, Bertholon P, Waterston J, Lee H, Bisdorff A, Strupp M
J Vestib Res 2022;32(3):205-222. doi: 10.3233/VES-210169. PMID: 35367974Free PMC Article
Cerebellar Dizziness and Vertigo: Etiologies, Diagnostic Assessment, and Treatment.
Zwergal A, Feil K, Schniepp R, Strupp M
Semin Neurol 2020 Feb;40(1):87-96. Epub 2019 Dec 30 doi: 10.1055/s-0039-3400315. PMID: 31887755
Diagnostic criteria for persistent postural-perceptual dizziness (PPPD): Consensus document of the committee for the Classification of Vestibular Disorders of the Bárány Society.
Staab JP, Eckhardt-Henn A, Horii A, Jacob R, Strupp M, Brandt T, Bronstein A
J Vestib Res 2017;27(4):191-208. doi: 10.3233/VES-170622. PMID: 29036855Free PMC Article
The epidemiology of dizziness and vertigo.
Neuhauser HK
Handb Clin Neurol 2016;137:67-82. doi: 10.1016/B978-0-444-63437-5.00005-4. PMID: 27638063

Diagnosis

Dizziness: Evaluation and Management.
Rogers TS, Noel MA, Garcia B
Am Fam Physician 2023 May;107(5):514-523. PMID: 37192077
Suboccipital Muscles, Forward Head Posture, and Cervicogenic Dizziness.
Sung YH
Medicina (Kaunas) 2022 Dec 5;58(12) doi: 10.3390/medicina58121791. PMID: 36556992Free PMC Article
Vascular vertigo and dizziness: Diagnostic criteria.
Kim JS, Newman-Toker DE, Kerber KA, Jahn K, Bertholon P, Waterston J, Lee H, Bisdorff A, Strupp M
J Vestib Res 2022;32(3):205-222. doi: 10.3233/VES-210169. PMID: 35367974Free PMC Article
Persistent Postural-Perceptual Dizziness.
Staab JP
Semin Neurol 2020 Feb;40(1):130-137. Epub 2020 Jan 14 doi: 10.1055/s-0039-3402736. PMID: 31935771
Persistent postural-perceptual dizziness (PPPD): a common, characteristic and treatable cause of chronic dizziness.
Popkirov S, Staab JP, Stone J
Pract Neurol 2018 Feb;18(1):5-13. Epub 2017 Dec 5 doi: 10.1136/practneurol-2017-001809. PMID: 29208729

Therapy

Vestibular Disorders.
Strupp M, Dlugaiczyk J, Ertl-Wagner BB, Rujescu D, Westhofen M, Dieterich M
Dtsch Arztebl Int 2020 Apr 24;117(17):300-310. doi: 10.3238/arztebl.2020.0300. PMID: 32530417Free PMC Article
Gepirone hydrochloride: a novel antidepressant with 5-HT1A agonistic properties.
Kaur Gill A, Bansal Y, Bhandari R, Kaur S, Kaur J, Singh R, Kuhad A, Kuhad A
Drugs Today (Barc) 2019 Jul;55(7):423-437. doi: 10.1358/dot.2019.55.7.2958474. PMID: 31347611
Treatment of fatigue in amyotrophic lateral sclerosis/motor neuron disease.
Gibbons C, Pagnini F, Friede T, Young CA
Cochrane Database Syst Rev 2018 Jan 2;1(1):CD011005. doi: 10.1002/14651858.CD011005.pub2. PMID: 29293261Free PMC Article
The Safety of Melatonin in Humans.
Andersen LP, Gögenur I, Rosenberg J, Reiter RJ
Clin Drug Investig 2016 Mar;36(3):169-75. doi: 10.1007/s40261-015-0368-5. PMID: 26692007
Vestibular rehabilitation for unilateral peripheral vestibular dysfunction.
McDonnell MN, Hillier SL
Cochrane Database Syst Rev 2015 Jan 13;1(1):CD005397. doi: 10.1002/14651858.CD005397.pub4. PMID: 25581507Free PMC Article

Prognosis

Effectiveness of conventional versus virtual reality-based vestibular rehabilitation exercises in elderly patients with dizziness: a randomized controlled study with 6-month follow-up.
Kanyılmaz T, Topuz O, Ardıç FN, Alkan H, Öztekin SNS, Topuz B, Ardıç F
Braz J Otorhinolaryngol 2022 Nov-Dec;88 Suppl 3(Suppl 3):S41-S49. Epub 2021 Oct 26 doi: 10.1016/j.bjorl.2021.08.010. PMID: 34799265Free PMC Article
Adverse reactions to radiopharmaceuticals.
Pérez-Iruela JA, Pastor-Fructuoso P, De Gracia-Rodríguez C, Soler-Vigil M, Gómez-Martínez MDV
Farm Hosp 2021 Mar 30;45(3):142-149. doi: 10.7399/fh.11669. PMID: 33941058
Autonomic dysfunction in 'long COVID': rationale, physiology and management strategies.
Dani M, Dirksen A, Taraborrelli P, Torocastro M, Panagopoulos D, Sutton R, Lim PB
Clin Med (Lond) 2021 Jan;21(1):e63-e67. Epub 2020 Nov 26 doi: 10.7861/clinmed.2020-0896. PMID: 33243837Free PMC Article
Seated postural hypotension.
Gorelik O, Cohen N
J Am Soc Hypertens 2015 Dec;9(12):985-92. Epub 2015 Oct 9 doi: 10.1016/j.jash.2015.10.001. PMID: 26515671
The tramadol option.
Desmeules JA
Eur J Pain 2000;4 Suppl A:15-21. PMID: 11310478

Clinical prediction guides

Effect of betahistine treatment on dizziness and anxiety symptoms of BPPV patients.
Erdur ZB, Evran N
Niger J Clin Pract 2023 Sep;26(9):1383-1387. doi: 10.4103/njcp.njcp_305_23. PMID: 37794554
Betahistine add-on therapy for treatment of subjects with posterior benign paroxysmal positional vertigo: a randomized controlled trial.
Sayin I, Koç RH, Temirbekov D, Gunes S, Cirak M, Yazici ZM
Braz J Otorhinolaryngol 2022 May-Jun;88(3):421-426. Epub 2020 Sep 12 doi: 10.1016/j.bjorl.2020.07.011. PMID: 32978116Free PMC Article
Efficacy of Epley Maneuver on Quality of Life of Elderly Patients with Subjective BPPV.
Uz U, Uz D, Akdal G, Çelik O
J Int Adv Otol 2019 Dec;15(3):420-424. doi: 10.5152/iao.2019.6483. PMID: 31846923Free PMC Article
Dizziness handicap and clinical characteristics of posterior and lateral canal BPPV.
Martens C, Goplen FK, Aasen T, Nordfalk KF, Nordahl SHG
Eur Arch Otorhinolaryngol 2019 Aug;276(8):2181-2189. Epub 2019 May 14 doi: 10.1007/s00405-019-05459-9. PMID: 31089808
Use of HINTS in the acute vestibular syndrome. An Overview.
Kattah JC
Stroke Vasc Neurol 2018 Dec;3(4):190-196. Epub 2018 Jun 23 doi: 10.1136/svn-2018-000160. PMID: 30637123Free PMC Article

Recent systematic reviews

Pharmacological interventions for persistent postural-perceptual dizziness (PPPD).
Webster KE, Harrington-Benton NA, Judd O, Kaski D, Maarsingh OR, MacKeith S, Ray J, Van Vugt VA, Burton MJ
Cochrane Database Syst Rev 2023 Mar 9;3(3):CD015188. doi: 10.1002/14651858.CD015188.pub2. PMID: 36906836Free PMC Article
Cannabis-Based Products for Chronic Pain : A Systematic Review.
McDonagh MS, Morasco BJ, Wagner J, Ahmed AY, Fu R, Kansagara D, Chou R
Ann Intern Med 2022 Aug;175(8):1143-1153. Epub 2022 Jun 7 doi: 10.7326/M21-4520. PMID: 35667066
Safety of higher doses of melatonin in adults: A systematic review and meta-analysis.
Menczel Schrire Z, Phillips CL, Chapman JL, Duffy SL, Wong G, D'Rozario AL, Comas M, Raisin I, Saini B, Gordon CJ, McKinnon AC, Naismith SL, Marshall NS, Grunstein RR, Hoyos CM
J Pineal Res 2022 Mar;72(2):e12782. Epub 2021 Dec 30 doi: 10.1111/jpi.12782. PMID: 34923676
Hearing Loss, Tinnitus, and Dizziness in COVID-19: A Systematic Review and Meta-Analysis.
Jafari Z, Kolb BE, Mohajerani MH
Can J Neurol Sci 2022 Mar;49(2):184-195. Epub 2021 Apr 12 doi: 10.1017/cjn.2021.63. PMID: 33843530Free PMC Article
Pregabalin for neuropathic pain in adults.
Derry S, Bell RF, Straube S, Wiffen PJ, Aldington D, Moore RA
Cochrane Database Syst Rev 2019 Jan 23;1(1):CD007076. doi: 10.1002/14651858.CD007076.pub3. PMID: 30673120Free PMC Article

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    Practice guidelines

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