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Dizziness

MedGen UID:
4360
•Concept ID:
C0012833
•
Sign or Symptom
Synonym: Dizzyness
SNOMED CT: Dizziness (404640003); Dizzy (404640003)

Definition

A sensation of lightheadedness, unsteadiness, turning, spinning or rocking. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDizziness

Professional guidelines

PubMed

Benign paroxysmal positional vertigo: Effective diagnosis and treatment.
Cole SR, Honaker JA
Cleve Clin J Med 2022 Nov 1;89(11):653-662. doi: 10.3949/ccjm.89a.21057. PMID: 36319052
Upper Gastrointestinal Bleeding in Adults: Evaluation and Management.
Wilkins T, Wheeler B, Carpenter M
Am Fam Physician 2020 Mar 1;101(5):294-300. PMID: 32109037
Clinical Practice Guideline: Benign Paroxysmal Positional Vertigo (Update).
Bhattacharyya N, Gubbels SP, Schwartz SR, Edlow JA, El-Kashlan H, Fife T, Holmberg JM, Mahoney K, Hollingsworth DB, Roberts R, Seidman MD, Steiner RW, Do BT, Voelker CC, Waguespack RW, Corrigan MD
Otolaryngol Head Neck Surg 2017 Mar;156(3_suppl):S1-S47. doi: 10.1177/0194599816689667. PMID: 28248609

Recent clinical studies

Etiology

Effectiveness of conventional versus virtual reality-based vestibular rehabilitation exercises in elderly patients with dizziness: a randomized controlled study with 6-month follow-up.
Kanyılmaz T, Topuz O, Ardıç FN, Alkan H, Öztekin SNS, Topuz B, Ardıç F
Braz J Otorhinolaryngol 2022 Nov-Dec;88 Suppl 3(Suppl 3):S41-S49. Epub 2021 Oct 26 doi: 10.1016/j.bjorl.2021.08.010. PMID: 34799265Free PMC Article
Chronic Dizziness.
Cha YH
Continuum (Minneap Minn) 2021 Apr 1;27(2):420-446. doi: 10.1212/CON.0000000000000932. PMID: 34351113
Episodic Spontaneous Dizziness.
Eggers SDZ
Continuum (Minneap Minn) 2021 Apr 1;27(2):369-401. doi: 10.1212/CON.0000000000000931. PMID: 34351111
Acute Dizziness.
Gurley KL, Edlow JA
Semin Neurol 2019 Feb;39(1):27-40. Epub 2019 Feb 11 doi: 10.1055/s-0038-1676857. PMID: 30743290
Diagnostic criteria for persistent postural-perceptual dizziness (PPPD): Consensus document of the committee for the Classification of Vestibular Disorders of the Bárány Society.
Staab JP, Eckhardt-Henn A, Horii A, Jacob R, Strupp M, Brandt T, Bronstein A
J Vestib Res 2017;27(4):191-208. doi: 10.3233/VES-170622. PMID: 29036855Free PMC Article

Diagnosis

Chronic Dizziness.
Cha YH
Continuum (Minneap Minn) 2021 Apr 1;27(2):420-446. doi: 10.1212/CON.0000000000000932. PMID: 34351113
Persistent Postural-Perceptual Dizziness.
Staab JP
Semin Neurol 2020 Feb;40(1):130-137. Epub 2020 Jan 14 doi: 10.1055/s-0039-3402736. PMID: 31935771
Vestibular Migraine.
Lempert T, von Brevern M
Neurol Clin 2019 Nov;37(4):695-706. Epub 2019 Aug 20 doi: 10.1016/j.ncl.2019.06.003. PMID: 31563227
Persistent postural-perceptual dizziness (PPPD): a common, characteristic and treatable cause of chronic dizziness.
Popkirov S, Staab JP, Stone J
Pract Neurol 2018 Feb;18(1):5-13. Epub 2017 Dec 5 doi: 10.1136/practneurol-2017-001809. PMID: 29208729
Dizziness: a diagnostic approach.
Post RE, Dickerson LM
Am Fam Physician 2010 Aug 15;82(4):361-8, 369. PMID: 20704166

Therapy

Vestibular Disorders.
Strupp M, Dlugaiczyk J, Ertl-Wagner BB, Rujescu D, Westhofen M, Dieterich M
Dtsch Arztebl Int 2020 Apr 24;117(17):300-310. doi: 10.3238/arztebl.2020.0300. PMID: 32530417Free PMC Article
Gepirone hydrochloride: a novel antidepressant with 5-HT1A agonistic properties.
Kaur Gill A, Bansal Y, Bhandari R, Kaur S, Kaur J, Singh R, Kuhad A, Kuhad A
Drugs Today (Barc) 2019 Jul;55(7):423-437. doi: 10.1358/dot.2019.55.7.2958474. PMID: 31347611
Treatment of fatigue in amyotrophic lateral sclerosis/motor neuron disease.
Gibbons C, Pagnini F, Friede T, Young CA
Cochrane Database Syst Rev 2018 Jan 2;1(1):CD011005. doi: 10.1002/14651858.CD011005.pub2. PMID: 29293261Free PMC Article
The Safety of Melatonin in Humans.
Andersen LP, Gögenur I, Rosenberg J, Reiter RJ
Clin Drug Investig 2016 Mar;36(3):169-75. doi: 10.1007/s40261-015-0368-5. PMID: 26692007
Vestibular rehabilitation for unilateral peripheral vestibular dysfunction.
McDonnell MN, Hillier SL
Cochrane Database Syst Rev 2015 Jan 13;1(1):CD005397. doi: 10.1002/14651858.CD005397.pub4. PMID: 25581507Free PMC Article

Prognosis

Relationship between periodontal disease and dizziness in Taiwanese adults: A nationwide population-based cohort study.
Huang FM, Luo CW, Lee SS, Ho YC, Li YC, Chang YC, Kuan YH
Medicine (Baltimore) 2023 Feb 22;102(8):e32961. doi: 10.1097/MD.0000000000032961. PMID: 36827024Free PMC Article
Effectiveness of conventional versus virtual reality-based vestibular rehabilitation exercises in elderly patients with dizziness: a randomized controlled study with 6-month follow-up.
Kanyılmaz T, Topuz O, Ardıç FN, Alkan H, Öztekin SNS, Topuz B, Ardıç F
Braz J Otorhinolaryngol 2022 Nov-Dec;88 Suppl 3(Suppl 3):S41-S49. Epub 2021 Oct 26 doi: 10.1016/j.bjorl.2021.08.010. PMID: 34799265Free PMC Article
Autonomic dysfunction in 'long COVID': rationale, physiology and management strategies.
Dani M, Dirksen A, Taraborrelli P, Torocastro M, Panagopoulos D, Sutton R, Lim PB
Clin Med (Lond) 2021 Jan;21(1):e63-e67. Epub 2020 Nov 26 doi: 10.7861/clinmed.2020-0896. PMID: 33243837Free PMC Article
Revision stapes surgery.
Ozüer MZ, Olgun L, Gültekin G
Otolaryngol Head Neck Surg 2012 Jan;146(1):109-13. Epub 2011 Sep 22 doi: 10.1177/0194599811423523. PMID: 21940991
Recurrent vestibulopathy.
Leliever WC, Barber HO
Laryngoscope 1981 Jan;91(1):1-6. doi: 10.1288/00005537-198101000-00001. PMID: 6969834

Clinical prediction guides

Motorist disorientation syndrome; clinical features and vestibular findings.
Ainsworth C, Davies R, Colvin I, Murdin L
J Vestib Res 2023;33(5):339-348. doi: 10.3233/VES-220088. PMID: 37248928Free PMC Article
Dizziness, Psychosocial Function, and Postural Stability Following Sport-Related Concussion.
Hunt DL, Oldham J, Aaron SE, Tan CO, Meehan WP 3rd, Howell DR
Clin J Sport Med 2022 Jul 1;32(4):361-367. Epub 2021 Mar 9 doi: 10.1097/JSM.0000000000000923. PMID: 34009789Free PMC Article
Efficacy of Epley Maneuver on Quality of Life of Elderly Patients with Subjective BPPV.
Uz U, Uz D, Akdal G, Çelik O
J Int Adv Otol 2019 Dec;15(3):420-424. doi: 10.5152/iao.2019.6483. PMID: 31846923Free PMC Article
Use of HINTS in the acute vestibular syndrome. An Overview.
Kattah JC
Stroke Vasc Neurol 2018 Dec;3(4):190-196. Epub 2018 Jun 23 doi: 10.1136/svn-2018-000160. PMID: 30637123Free PMC Article
Repositioning nystagmus: prognostic usefulness?
Marques PS, Castillo R, Santos M, Perez-Fernandez N
Acta Otolaryngol 2014 May;134(5):491-6. doi: 10.3109/00016489.2013.872291. PMID: 24702229

Recent systematic reviews

Non-pharmacological interventions for persistent postural-perceptual dizziness (PPPD).
Webster KE, Kamo T, Smith L, Harrington-Benton NA, Judd O, Kaski D, Maarsingh OR, MacKeith S, Ray J, Van Vugt VA, Burton MJ
Cochrane Database Syst Rev 2023 Mar 13;3(3):CD015333. doi: 10.1002/14651858.CD015333.pub2. PMID: 36912784Free PMC Article
Pharmacological interventions for persistent postural-perceptual dizziness (PPPD).
Webster KE, Harrington-Benton NA, Judd O, Kaski D, Maarsingh OR, MacKeith S, Ray J, Van Vugt VA, Burton MJ
Cochrane Database Syst Rev 2023 Mar 9;3(3):CD015188. doi: 10.1002/14651858.CD015188.pub2. PMID: 36906836Free PMC Article
Systematic review and meta-analysis of the therapeutic management of patients with cervicogenic dizziness.
De Vestel C, Vereeck L, Reid SA, Van Rompaey V, Lemmens J, De Hertogh W
J Man Manip Ther 2022 Oct;30(5):273-283. Epub 2022 Apr 6 doi: 10.1080/10669817.2022.2033044. PMID: 35383538Free PMC Article
Lacosamide in status epilepticus: Systematic review of current evidence.
Strzelczyk A, Zöllner JP, Willems LM, Jost J, Paule E, Schubert-Bast S, Rosenow F, Bauer S
Epilepsia 2017 Jun;58(6):933-950. Epub 2017 Mar 11 doi: 10.1111/epi.13716. PMID: 28295226
Vestibular rehabilitation for unilateral peripheral vestibular dysfunction.
McDonnell MN, Hillier SL
Cochrane Database Syst Rev 2015 Jan 13;1(1):CD005397. doi: 10.1002/14651858.CD005397.pub4. PMID: 25581507Free PMC Article

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