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Dentin sensitivity

MedGen UID:
41477
•Concept ID:
C0011432
•
Disease or Syndrome
Synonyms: Dentin Hypersensitivities; Dentin Hypersensitivity; Dentin Sensitivities; Dentin Sensitivity; Dentine Hypersensitivities; Dentine Hypersensitivity; Dentine Sensitivities; Dentine Sensitivity; Hypersensitivities, Dentin; Hypersensitivities, Dentine; Hypersensitivity, Dentin; Hypersensitivity, Dentine; Sensitivities, Dentin; Sensitivities, Dentine; Sensitivities, Tooth; Sensitivity, Dentin; Sensitivity, Dentine; Sensitivity, Tooth; Tooth Sensitivities; Tooth Sensitivity
SNOMED CT: Sensitive dentin (13468005); Tooth sensitivity (13468005); Dentine hypersensitivity (13468005); Tooth hypersensitivity (13468005); Dentine sensitivity (13468005)
 
Monarch Initiative: MONDO:0004059

Definition

Pain or discomfort caused by exposure of the dentin layer of tooth to thermal, tactile, or other stimuli. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDentin sensitivity

Professional guidelines

PubMed

Self-propelled bioglass janus nanomotors for dentin hypersensitivity treatment.
Wu W, Chi H, Zhang Q, Zheng C, Hu N, Wu Y, Liu J
Nanoscale 2023 Dec 14;15(48):19681-19690. doi: 10.1039/d3nr03685e. PMID: 38037416
Lasers for the treatment of dentin hypersensitivity: a meta-analysis.
Sgolastra F, Petrucci A, Severino M, Gatto R, Monaco A
J Dent Res 2013 Jun;92(6):492-9. Epub 2013 Apr 22 doi: 10.1177/0022034513487212. PMID: 23609160
How valid and applicable are current diagnostic criteria and assessment methods for dentin hypersensitivity? An overview.
Gernhardt CR
Clin Oral Investig 2013 Mar;17 Suppl 1(Suppl 1):S31-40. Epub 2012 Dec 6 doi: 10.1007/s00784-012-0891-1. PMID: 23224044Free PMC Article

Recent clinical studies

Etiology

Treatment outcome for dentin hypersensitivity with laser therapy: Systematic review and meta-analysis.
Pion LA, Matos LLM, Gimenez T, Palma-Dibb RG, Faraoni JJ
Dent Med Probl 2023 Jan-Mar;60(1):153-166. doi: 10.17219/dmp/151482. PMID: 37023343
Pathogenesis, diagnosis and management of dentin hypersensitivity: an evidence-based overview for dental practitioners.
Liu XX, Tenenbaum HC, Wilder RS, Quock R, Hewlett ER, Ren YF
BMC Oral Health 2020 Aug 6;20(1):220. doi: 10.1186/s12903-020-01199-z. PMID: 32762733Free PMC Article
Evaluation of the efficacy of dentin hypersensitivity treatments-A systematic review and follow-up analysis.
Marto CM, Baptista Paula A, Nunes T, Pimenta M, Abrantes AM, Pires AS, Laranjo M, Coelho A, Donato H, Botelho MF, Marques Ferreira M, Carrilho E
J Oral Rehabil 2019 Oct;46(10):952-990. Epub 2019 Jul 12 doi: 10.1111/joor.12842. PMID: 31216069
Clinical evaluation of color change and tooth sensitivity with in-office and home bleaching treatments.
Mounika A, Mandava J, Roopesh B, Karri G
Indian J Dent Res 2018 Jul-Aug;29(4):423-427. doi: 10.4103/ijdr.IJDR_688_16. PMID: 30127190
Dentin hypersensitivity: pain mechanisms and aetiology of exposed cervical dentin.
West NX, Lussi A, Seong J, Hellwig E
Clin Oral Investig 2013 Mar;17 Suppl 1:S9-19. Epub 2012 Dec 9 doi: 10.1007/s00784-012-0887-x. PMID: 23224116

Diagnosis

Successful management of dentin hypersensitivity: A narrative review.
Ramli R, Ghani N, Taib H, Mat-Baharin NH
Dent Med Probl 2022 Jul-Sep;59(3):451-460. doi: 10.17219/dmp/143354. PMID: 36206495
Pathogenesis, diagnosis and management of dentin hypersensitivity: an evidence-based overview for dental practitioners.
Liu XX, Tenenbaum HC, Wilder RS, Quock R, Hewlett ER, Ren YF
BMC Oral Health 2020 Aug 6;20(1):220. doi: 10.1186/s12903-020-01199-z. PMID: 32762733Free PMC Article
Clinical evaluation of color change and tooth sensitivity with in-office and home bleaching treatments.
Mounika A, Mandava J, Roopesh B, Karri G
Indian J Dent Res 2018 Jul-Aug;29(4):423-427. doi: 10.4103/ijdr.IJDR_688_16. PMID: 30127190
Age-related morphological, histological and functional changes in teeth.
Carvalho TS, Lussi A
J Oral Rehabil 2017 Apr;44(4):291-298. Epub 2017 Jan 28 doi: 10.1111/joor.12474. PMID: 28032898
Dentin hypersensitivity: pain mechanisms and aetiology of exposed cervical dentin.
West NX, Lussi A, Seong J, Hellwig E
Clin Oral Investig 2013 Mar;17 Suppl 1:S9-19. Epub 2012 Dec 9 doi: 10.1007/s00784-012-0887-x. PMID: 23224116

Therapy

Formulations of desensitizing toothpastes for dentin hypersensitivity: a scoping review.
Martins CC, Riva JJ, Firmino RT, Schünemann HJ
J Appl Oral Sci 2022;30:e20210410. Epub 2022 Mar 7 doi: 10.1590/1678-7757-2021-0410. PMID: 35262559Free PMC Article
Effect of violet LED light on in-office bleaching protocols: a randomized controlled clinical trial.
Kury M, Wada EE, Silva DPD, Tabchoury CPM, Giannini M, Cavalli V
J Appl Oral Sci 2020;28:e20190720. Epub 2020 May 18 doi: 10.1590/1678-7757-2019-0720. PMID: 32428059Free PMC Article
Network meta-analysis on the effect of desensitizing toothpastes on dentine hypersensitivity.
Hu ML, Zheng G, Lin H, Yang M, Zhang YD, Han JM
J Dent 2019 Sep;88:103170. Epub 2019 Jul 17 doi: 10.1016/j.jdent.2019.07.008. PMID: 31325467
Association Between In-Office And At-Home Tooth Bleaching: A Single Blind Randomized Clinical Trial.
Rodrigues JL, Rocha PS, Pardim SLS, Machado ACV, Faria-E-Silva AL, Seraidarian PI
Braz Dent J 2018 Mar-Apr;29(2):133-139. doi: 10.1590/0103-6440201801726. PMID: 29898058
Dentin desensitizing agents: too many options.
AlKahtani R
Gen Dent 2017 Sep-Oct;65(5):17-20. PMID: 28862583

Prognosis

Clinical Efficacy of Different Dentin Desensitizers.
Eyüboğlu GB, Naiboğlu P
Oper Dent 2020 Nov 1;45(6):E317-E333. doi: 10.2341/19-258-C. PMID: 32516395
Evaluation of the efficacy of dentin hypersensitivity treatments-A systematic review and follow-up analysis.
Marto CM, Baptista Paula A, Nunes T, Pimenta M, Abrantes AM, Pires AS, Laranjo M, Coelho A, Donato H, Botelho MF, Marques Ferreira M, Carrilho E
J Oral Rehabil 2019 Oct;46(10):952-990. Epub 2019 Jul 12 doi: 10.1111/joor.12842. PMID: 31216069
Control of dentin/root sensitivity during non-surgical and surgical periodontal treatment.
Giassin NP, Apatzidou DA, Solomou K, Mateo LR, Panagakos FS, Konstantinidis A
J Clin Periodontol 2016 Feb;43(2):138-46. Epub 2016 Mar 1 doi: 10.1111/jcpe.12490. PMID: 26660591
Treatment of dentin hypersensitivity.
Trushkowsky RD, Oquendo A
Dent Clin North Am 2011 Jul;55(3):599-608, x. doi: 10.1016/j.cden.2011.02.013. PMID: 21726693
Understanding and managing dentin hypersensitivity.
Tilliss TS, Keating JG
J Dent Hyg 2002 Fall;76(4):296-310; quiz 311-3. PMID: 12592921

Clinical prediction guides

Treatment outcome for dentin hypersensitivity with laser therapy: Systematic review and meta-analysis.
Pion LA, Matos LLM, Gimenez T, Palma-Dibb RG, Faraoni JJ
Dent Med Probl 2023 Jan-Mar;60(1):153-166. doi: 10.17219/dmp/151482. PMID: 37023343
Evaluation of the efficacy of dentin hypersensitivity treatments-A systematic review and follow-up analysis.
Marto CM, Baptista Paula A, Nunes T, Pimenta M, Abrantes AM, Pires AS, Laranjo M, Coelho A, Donato H, Botelho MF, Marques Ferreira M, Carrilho E
J Oral Rehabil 2019 Oct;46(10):952-990. Epub 2019 Jul 12 doi: 10.1111/joor.12842. PMID: 31216069
At-home vs In-office Bleaching: A Systematic Review and Meta-analysis.
de Geus JL, Wambier LM, Kossatz S, Loguercio AD, Reis A
Oper Dent 2016 Jul-Aug;41(4):341-56. Epub 2016 Apr 5 doi: 10.2341/15-287-LIT. PMID: 27045285
Epidemiology of dentin hypersensitivity.
Splieth CH, Tachou A
Clin Oral Investig 2013 Mar;17 Suppl 1(Suppl 1):S3-8. Epub 2012 Dec 7 doi: 10.1007/s00784-012-0889-8. PMID: 23224064Free PMC Article
Treatment of dentin hypersensitivity.
Trushkowsky RD, Oquendo A
Dent Clin North Am 2011 Jul;55(3):599-608, x. doi: 10.1016/j.cden.2011.02.013. PMID: 21726693

Recent systematic reviews

Treatment outcome for dentin hypersensitivity with laser therapy: Systematic review and meta-analysis.
Pion LA, Matos LLM, Gimenez T, Palma-Dibb RG, Faraoni JJ
Dent Med Probl 2023 Jan-Mar;60(1):153-166. doi: 10.17219/dmp/151482. PMID: 37023343
Evaluation of the efficacy of dentin hypersensitivity treatments-A systematic review and follow-up analysis.
Marto CM, Baptista Paula A, Nunes T, Pimenta M, Abrantes AM, Pires AS, Laranjo M, Coelho A, Donato H, Botelho MF, Marques Ferreira M, Carrilho E
J Oral Rehabil 2019 Oct;46(10):952-990. Epub 2019 Jul 12 doi: 10.1111/joor.12842. PMID: 31216069
Prevalence of dentin hypersensitivity: Systematic review and meta-analysis.
Favaro Zeola L, Soares PV, Cunha-Cruz J
J Dent 2019 Feb;81:1-6. Epub 2019 Jan 11 doi: 10.1016/j.jdent.2018.12.015. PMID: 30639724
At-home vs In-office Bleaching: A Systematic Review and Meta-analysis.
de Geus JL, Wambier LM, Kossatz S, Loguercio AD, Reis A
Oper Dent 2016 Jul-Aug;41(4):341-56. Epub 2016 Apr 5 doi: 10.2341/15-287-LIT. PMID: 27045285
Arginine-containing toothpastes for dentin hypersensitivity: systematic review and meta-analysis.
Yan B, Yi J, Li Y, Chen Y, Shi Z
Quintessence Int 2013 Oct;44(9):709-23. doi: 10.3290/j.qi.a30177. PMID: 23878846

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