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Dens in dente

MedGen UID:
41452
•Concept ID:
C0011320
•
Congenital Abnormality
Synonyms: Dens in Dente; Dens in Dentes; Dente, Dens in; Dentes, Dens in; in Dente, Dens; in Dentes, Dens
SNOMED CT: Invaginated odontome (55197001); Dens in dente (55197001); Dens invaginatus (55197001); Invagination of cusp of crown of tooth (55197001); Invagination of crown of tooth (55197001)
 
HPO: HP:0011088

Definition

An abnormality of the incisor characterized by invagination of the enamel, giving a radiographic appearance that suggests a tooth within a tooth. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDens in dente

Professional guidelines

PubMed

Dens Invaginatus: Clinical Implications and Antimicrobial Endodontic Treatment Considerations.
Siqueira JF Jr, Rôças IN, Hernández SR, Brisson-Suárez K, Baasch AC, Pérez AR, Alves FRF
J Endod 2022 Feb;48(2):161-170. Epub 2021 Dec 11 doi: 10.1016/j.joen.2021.11.014. PMID: 34902355

Recent clinical studies

Etiology

Conservative management of dens in dente.
Castelo-Baz P, Gancedo-Gancedo T, Pereira-Lores P, Mosquera-Barreiro C, Martín-Biedma B, Faus-Matoses V, Ruíz-Piñón M
Aust Endod J 2023 Sep;49 Suppl 1:481-487. Epub 2023 May 8 doi: 10.1111/aej.12763. PMID: 37154212
Prevalence and morphological analysis of dens invaginatus in anterior teeth using cone beam computed tomography: A systematic review and meta-analysis.
Alves Dos Santos GN, Sousa-Neto MD, Assis HC, Lopes-Olhê FC, Faria-E-Silva AL, Oliveira ML, Mazzi-Chaves JF, Candemil AP
Arch Oral Biol 2023 Jul;151:105715. Epub 2023 May 1 doi: 10.1016/j.archoralbio.2023.105715. PMID: 37146389
Assessment of dens invaginatus and its characteristics in maxillary anterior teeth using cone-beam computed tomography.
Alkadi M, Almohareb R, Mansour S, Mehanny M, Alsadhan R
Sci Rep 2021 Oct 5;11(1):19727. doi: 10.1038/s41598-021-99258-0. PMID: 34611255Free PMC Article
Dens invaginatus: a review and orthodontic implications.
Chaturvedula BB, Muthukrishnan A, Bhuvaraghan A, Sandler J, Thiruvenkatachari B
Br Dent J 2021 Mar;230(6):345-350. Epub 2021 Mar 26 doi: 10.1038/s41415-021-2721-9. PMID: 33772187
The apical barrier technique in a "dens in dente".
Castellucci A
Dent Today 2005 Sep;24(9):78, 80, 82 passim; quiz 87. PMID: 16229295

Diagnosis

Conservative management of dens in dente.
Castelo-Baz P, Gancedo-Gancedo T, Pereira-Lores P, Mosquera-Barreiro C, Martín-Biedma B, Faus-Matoses V, Ruíz-Piñón M
Aust Endod J 2023 Sep;49 Suppl 1:481-487. Epub 2023 May 8 doi: 10.1111/aej.12763. PMID: 37154212
Dens invaginatus: a review and orthodontic implications.
Chaturvedula BB, Muthukrishnan A, Bhuvaraghan A, Sandler J, Thiruvenkatachari B
Br Dent J 2021 Mar;230(6):345-350. Epub 2021 Mar 26 doi: 10.1038/s41415-021-2721-9. PMID: 33772187
An update on the diagnosis and treatment of dens invaginatus.
Zhu J, Wang X, Fang Y, Von den Hoff JW, Meng L
Aust Dent J 2017 Sep;62(3):261-275. Epub 2017 May 22 doi: 10.1111/adj.12513. PMID: 28306163
Dens invaginatus: diagnosis and management strategies.
Gallacher A, Ali R, Bhakta S
Br Dent J 2016 Oct 7;221(7):383-387. doi: 10.1038/sj.bdj.2016.724. PMID: 27713460
Dens invaginatus: aetiology, classification, prevalence, diagnosis, and treatment considerations.
Hülsmann M
Int Endod J 1997 Mar;30(2):79-90. doi: 10.1046/j.1365-2591.1997.00065.x. PMID: 10332241

Therapy

Conservative management of dens in dente.
Castelo-Baz P, Gancedo-Gancedo T, Pereira-Lores P, Mosquera-Barreiro C, Martín-Biedma B, Faus-Matoses V, Ruíz-Piñón M
Aust Endod J 2023 Sep;49 Suppl 1:481-487. Epub 2023 May 8 doi: 10.1111/aej.12763. PMID: 37154212
Prevalence and morphological analysis of dens invaginatus in anterior teeth using cone beam computed tomography: A systematic review and meta-analysis.
Alves Dos Santos GN, Sousa-Neto MD, Assis HC, Lopes-Olhê FC, Faria-E-Silva AL, Oliveira ML, Mazzi-Chaves JF, Candemil AP
Arch Oral Biol 2023 Jul;151:105715. Epub 2023 May 1 doi: 10.1016/j.archoralbio.2023.105715. PMID: 37146389
Management of teeth with dens invaginatus and apical periodontitis: A case series.
Hernández SR, Pérez AR, Baasch AC, Brisson-Suárez K, Sellera DP, Ferrari PHP, Alberdi JC, Carreira CM, Gomes-Azevedo S, Alves FRF, Rôças IN, Siqueira JF Jr
J Am Dent Assoc 2022 May;153(5):470-478. Epub 2022 Feb 17 doi: 10.1016/j.adaj.2021.10.009. PMID: 35184866
Management of dens invaginatus type I and open apex: report of three cases.
Schmitz MS, Montagner F, Flores CB, Morari VH, Quesada GA, Gomes BP
J Endod 2010 Jun;36(6):1079-85. Epub 2010 Apr 18 doi: 10.1016/j.joen.2010.02.002. PMID: 20478470
The apical barrier technique in a "dens in dente".
Castellucci A
Dent Today 2005 Sep;24(9):78, 80, 82 passim; quiz 87. PMID: 16229295

Prognosis

Conservative management of dens in dente.
Castelo-Baz P, Gancedo-Gancedo T, Pereira-Lores P, Mosquera-Barreiro C, Martín-Biedma B, Faus-Matoses V, Ruíz-Piñón M
Aust Endod J 2023 Sep;49 Suppl 1:481-487. Epub 2023 May 8 doi: 10.1111/aej.12763. PMID: 37154212
Regenerative endodontic treatment of dens in dente in maxillary lateral incisor with immature root: a case report.
Yuan J, Yu S, You M, Zhang Q, Ye L, Gao B
Hua Xi Kou Qiang Yi Xue Za Zhi 2022 Dec 1;40(6):716-720. doi: 10.7518/hxkq.2022.06.014. PMID: 36416326Free PMC Article
Dens invaginatus: a review and orthodontic implications.
Chaturvedula BB, Muthukrishnan A, Bhuvaraghan A, Sandler J, Thiruvenkatachari B
Br Dent J 2021 Mar;230(6):345-350. Epub 2021 Mar 26 doi: 10.1038/s41415-021-2721-9. PMID: 33772187
The apical barrier technique in a "dens in dente".
Castellucci A
Dent Today 2005 Sep;24(9):78, 80, 82 passim; quiz 87. PMID: 16229295
Dens invaginatus--a pathway to pulpal pathology: a literature review.
Gound TG
Pract Periodontics Aesthet Dent 1997 Jun-Jul;9(5):585-94; quiz 596. PMID: 9550084

Clinical prediction guides

Prevalence and morphological analysis of dens invaginatus in anterior teeth using cone beam computed tomography: A systematic review and meta-analysis.
Alves Dos Santos GN, Sousa-Neto MD, Assis HC, Lopes-Olhê FC, Faria-E-Silva AL, Oliveira ML, Mazzi-Chaves JF, Candemil AP
Arch Oral Biol 2023 Jul;151:105715. Epub 2023 May 1 doi: 10.1016/j.archoralbio.2023.105715. PMID: 37146389
Prevalence, classification and dental treatment requirements of dens invaginatus by cone-beam computed tomography.
Yalcin TY, Bektaş Kayhan K, Yilmaz A, Göksel S, Ozcan İ, Helvacioglu Yigit D
PeerJ 2022;10:e14450. Epub 2022 Dec 5 doi: 10.7717/peerj.14450. PMID: 36523480Free PMC Article
Prevalence of dens invaginatus and its association with periapical lesions in a Western Indian population-a study using cone-beam computed tomography.
Hegde V, Mujawar A, Shanmugasundaram S, Sidhu P, Narasimhan S, Setzer FC, Nagendrababu V
Clin Oral Investig 2022 Sep;26(9):5875-5883. Epub 2022 Jun 1 doi: 10.1007/s00784-022-04545-3. PMID: 35648236
Assessment of dens invaginatus and its characteristics in maxillary anterior teeth using cone-beam computed tomography.
Alkadi M, Almohareb R, Mansour S, Mehanny M, Alsadhan R
Sci Rep 2021 Oct 5;11(1):19727. doi: 10.1038/s41598-021-99258-0. PMID: 34611255Free PMC Article
Investigation of dens invaginatus in a Chinese subpopulation using Cone-beam computed tomography.
Chen L, Li Y, Wang H
Oral Dis 2021 Oct;27(7):1755-1760. Epub 2020 Nov 20 doi: 10.1111/odi.13702. PMID: 33128413

Recent systematic reviews

Prevalence and morphological analysis of dens invaginatus in anterior teeth using cone beam computed tomography: A systematic review and meta-analysis.
Alves Dos Santos GN, Sousa-Neto MD, Assis HC, Lopes-Olhê FC, Faria-E-Silva AL, Oliveira ML, Mazzi-Chaves JF, Candemil AP
Arch Oral Biol 2023 Jul;151:105715. Epub 2023 May 1 doi: 10.1016/j.archoralbio.2023.105715. PMID: 37146389
Atypical Radicular Anatomy in Permanent Human Teeth: A Systematic Review.
Nino-Barrera J, Alzate-Mendoza D, Olaya-Abril C, Gamboa-Martinez LF, Guamán-Laverde M, Lagos-Rosero N, Romero-Diaz AC, Duran N, Vanegas-Hoyose L
Crit Rev Biomed Eng 2022;50(1):19-34. doi: 10.1615/CritRevBiomedEng.2022043742. PMID: 35997108

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