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Coronary thrombosis

MedGen UID:
3625
•Concept ID:
C0010072
•
Disease or Syndrome
Synonyms: Coronary Thromboses; Coronary Thrombosis; Thromboses, Coronary; Thrombosis, Coronary
SNOMED CT: Coronary artery thrombosis (398274000); CT - Coronary thrombosis (398274000); Coronary thrombosis (398274000); Thrombosis - coronary (398274000)
 
Monarch Initiative: MONDO:0006716

Definition

Coagulation of blood in any of the coronary vessels. The presence of a blood clot (thrombus) often leads to myocardial infarction. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCoronary thrombosis

Professional guidelines

PubMed

Diagnosis and Management of Congenital Coronary Artery Fistulas in Infants and Children.
Wu S, Fares M, Zellers TM, Jyothinagaram M, Reddy SRV
Curr Cardiol Rep 2023 Dec;25(12):1921-1932. Epub 2023 Dec 5 doi: 10.1007/s11886-023-02007-0. PMID: 38051412
De-escalation or abbreviation of dual antiplatelet therapy in acute coronary syndromes and percutaneous coronary intervention: a Consensus Statement from an international expert panel on coronary thrombosis.
Gorog DA, Ferreiro JL, Ahrens I, Ako J, Geisler T, Halvorsen S, Huber K, Jeong YH, Navarese EP, Rubboli A, Sibbing D, Siller-Matula JM, Storey RF, Tan JWC, Ten Berg JM, Valgimigli M, Vandenbriele C, Lip GYH
Nat Rev Cardiol 2023 Dec;20(12):830-844. Epub 2023 Jul 20 doi: 10.1038/s41569-023-00901-2. PMID: 37474795
Neonatal Myocardial Infarction: A Proposed Algorithm for Coronary Arterial Thrombus Management.
El-Sabrout H, Ganta S, Guyon P, Ratnayaka K, Vaughn G, Perry J, Kimball A, Ryan J, Thornburg CD, Tucker S, Mo J, Hegde S, Nigro J, El-Said H
Circ Cardiovasc Interv 2022 May;15(5):e011664. Epub 2022 Apr 29 doi: 10.1161/CIRCINTERVENTIONS.121.011664. PMID: 35485231Free PMC Article

Recent clinical studies

Therapy

A Genotype-Guided Strategy for Oral P2Y(12) Inhibitors in Primary PCI.
Claassens DMF, Vos GJA, Bergmeijer TO, Hermanides RS, van 't Hof AWJ, van der Harst P, Barbato E, Morisco C, Tjon Joe Gin RM, Asselbergs FW, Mosterd A, Herrman JR, Dewilde WJM, Janssen PWA, Kelder JC, Postma MJ, de Boer A, Boersma C, Deneer VHM, Ten Berg JM
N Engl J Med 2019 Oct 24;381(17):1621-1631. Epub 2019 Sep 3 doi: 10.1056/NEJMoa1907096. PMID: 31479209
Platelet Reactivity: Is There a Role to Switch?
Aradi D, Merkely B, Komócsi A
Prog Cardiovasc Dis 2015 Nov-Dec;58(3):278-84. Epub 2015 Aug 7 doi: 10.1016/j.pcad.2015.08.008. PMID: 26260612
Intravenous thrombolytics for ischemic stroke.
Barreto AD
Neurotherapeutics 2011 Jul;8(3):388-99. doi: 10.1007/s13311-011-0049-x. PMID: 21638138Free PMC Article
Heparin-coated stents.
Kocsis JF, Llanos G, Holmer E
J Long Term Eff Med Implants 2000;10(1-2):19-45. doi: 10.1615/jlongtermeffmedimplants.v10.i12.50. PMID: 10947628
Development of eptifibatide.
Scarborough RM
Am Heart J 1999 Dec;138(6 Pt 1):1093-104. doi: 10.1016/s0002-8703(99)70075-x. PMID: 10577440

Prognosis

Incidence and timing of coronary thrombosis in Kawasaki disease patients with giant coronary artery aneurysm.
Peng Y, Yi Q
Thromb Res 2023 Jan;221:30-34. Epub 2022 Nov 23 doi: 10.1016/j.thromres.2022.11.014. PMID: 36455387
Platelet activation and stent thrombosis.
Georgiadou P, Voudris V
Hellenic J Cardiol 2017 Jan-Feb;58(1):49-50. Epub 2017 Apr 7 doi: 10.1016/j.hjc.2017.03.013. PMID: 28396052
Pathophysiology of native coronary, vein graft, and in-stent atherosclerosis.
Yahagi K, Kolodgie FD, Otsuka F, Finn AV, Davis HR, Joner M, Virmani R
Nat Rev Cardiol 2016 Feb;13(2):79-98. Epub 2015 Oct 27 doi: 10.1038/nrcardio.2015.164. PMID: 26503410
SPONTANEOUS CORONARY ARTERY DISSECTION.
Jonjev Ž
Med Pregl 2015 Sep-Oct;68(9-10):337-40. doi: 10.2298/mpns1510337j. PMID: 26727831
Thrombosis in pediatric cardiac patients.
Monagle P
Semin Thromb Hemost 2003 Dec;29(6):547-55. doi: 10.1055/s-2004-815637. PMID: 14719171

Clinical prediction guides

Potential Mechanisms of In-stent Neointimal Atherosclerotic Plaque Formation.
Zhang DM, Chen SL
J Cardiovasc Pharmacol 2021 Sep 1;78(3):388-393. doi: 10.1097/FJC.0000000000001059. PMID: 34029271
Updated Expert Consensus Statement on Platelet Function and Genetic Testing for Guiding P2Y(12) Receptor Inhibitor Treatment in Percutaneous Coronary Intervention.
Sibbing D, Aradi D, Alexopoulos D, Ten Berg J, Bhatt DL, Bonello L, Collet JP, Cuisset T, Franchi F, Gross L, Gurbel P, Jeong YH, Mehran R, Moliterno DJ, Neumann FJ, Pereira NL, Price MJ, Sabatine MS, So DYF, Stone GW, Storey RF, Tantry U, Trenk D, Valgimigli M, Waksman R, Angiolillo DJ
JACC Cardiovasc Interv 2019 Aug 26;12(16):1521-1537. Epub 2019 Jun 12 doi: 10.1016/j.jcin.2019.03.034. PMID: 31202949
The role of echocardiography in Kawasaki disease.
McCrindle BW, Cifra B
Int J Rheum Dis 2018 Jan;21(1):50-55. Epub 2017 Nov 19 doi: 10.1111/1756-185X.13216. PMID: 29152929
Platelet Reactivity: Is There a Role to Switch?
Aradi D, Merkely B, Komócsi A
Prog Cardiovasc Dis 2015 Nov-Dec;58(3):278-84. Epub 2015 Aug 7 doi: 10.1016/j.pcad.2015.08.008. PMID: 26260612
Stent thrombosis: a clinical perspective.
Claessen BE, Henriques JP, Jaffer FA, Mehran R, Piek JJ, Dangas GD
JACC Cardiovasc Interv 2014 Oct;7(10):1081-92. doi: 10.1016/j.jcin.2014.05.016. PMID: 25341705

Recent systematic reviews

Nephrotic syndrome and acute coronary syndrome in children, teenagers and young adults: Systematic literature review.
Wolf O, Didier R, Chagué F, Bichat F, Rochette L, Zeller M, Fauchier L, Bonnotte B, Cottin Y
Arch Cardiovasc Dis 2023 May;116(5):282-290. Epub 2023 Apr 13 doi: 10.1016/j.acvd.2023.03.002. PMID: 37088677
Adverse events following COVID-19 mRNA vaccines: A systematic review of cardiovascular complication, thrombosis, and thrombocytopenia.
Yasmin F, Najeeb H, Naeem U, Moeed A, Atif AR, Asghar MS, Nimri N, Saleem M, Bandyopadhyay D, Krittanawong C, Fadelallah Eljack MM, Tahir MJ, Waqar F
Immun Inflamm Dis 2023 Mar;11(3):e807. doi: 10.1002/iid3.807. PMID: 36988252Free PMC Article
Anticoagulation in Acute Coronary Syndrome-State of the Art.
Zeitouni M, Kerneis M, Nafee T, Collet JP, Silvain J, Montalescot G
Prog Cardiovasc Dis 2018 Jan-Feb;60(4-5):508-513. Epub 2018 Jan 13 doi: 10.1016/j.pcad.2018.01.004. PMID: 29339166
Anticoagulation after coronary stenting: a systemic review.
Dong Z, Zheng J
Br Med Bull 2017 Sep 1;123(1):79-89. doi: 10.1093/bmb/ldx018. PMID: 28910988
Simultaneous multi-vessel coronary thrombosis in patients with ST-elevation myocardial infarction: a systematic review.
Mahmoud A, Saad M, Elgendy IY
Cardiovasc Revasc Med 2015 Apr-May;16(3):163-6. Epub 2015 Mar 5 doi: 10.1016/j.carrev.2015.02.009. PMID: 25772369

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