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Coronary thrombosis

MedGen UID:
3625
•Concept ID:
C0010072
•
Disease or Syndrome
Synonyms: Coronary Thromboses; Coronary Thrombosis; Thromboses, Coronary; Thrombosis, Coronary
SNOMED CT: Coronary artery thrombosis (398274000); CT - Coronary thrombosis (398274000); Coronary thrombosis (398274000); Thrombosis - coronary (398274000)
 
Monarch Initiative: MONDO:0006716

Definition

Coagulation of blood in any of the coronary vessels. The presence of a blood clot (thrombus) often leads to myocardial infarction. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCoronary thrombosis

Professional guidelines

PubMed

De-escalation or abbreviation of dual antiplatelet therapy in acute coronary syndromes and percutaneous coronary intervention: a Consensus Statement from an international expert panel on coronary thrombosis.
Gorog DA, Ferreiro JL, Ahrens I, Ako J, Geisler T, Halvorsen S, Huber K, Jeong YH, Navarese EP, Rubboli A, Sibbing D, Siller-Matula JM, Storey RF, Tan JWC, Ten Berg JM, Valgimigli M, Vandenbriele C, Lip GYH
Nat Rev Cardiol 2023 Dec;20(12):830-844. Epub 2023 Jul 20 doi: 10.1038/s41569-023-00901-2. PMID: 37474795
Electrocardiographic Diagnosis of Acute Coronary Occlusion Myocardial Infarction in Ventricular Paced Rhythm Using the Modified Sgarbossa Criteria.
Dodd KW, Zvosec DL, Hart MA, Glass G 3rd, Bannister LE, Body RM, Boggust BA, Brady WJ, Chang AM, Cullen L, Gómez-Vicente R, Huis In 't Veld MA, Karim RM, Meyers HP 3rd, Miranda DF, Mitchell GJ, Reynard C, Rice C, Salverda BJ, Stellpflug SJ, Tolia VM, Walsh BM, White JL, Smith SW; PERFECT study investigators (the complete list of PERFECT study investigators is provided in Appendix E1, available at http://www.annemergmed.com)
Ann Emerg Med 2021 Oct;78(4):517-529. Epub 2021 Jun 23 doi: 10.1016/j.annemergmed.2021.03.036. PMID: 34172301
Lifetime cardiovascular management of patients with previous Kawasaki disease.
Brogan P, Burns JC, Cornish J, Diwakar V, Eleftheriou D, Gordon JB, Gray HH, Johnson TW, Levin M, Malik I, MacCarthy P, McCormack R, Miller O, Tulloh RMR; Kawasaki Disease Writing Group, on behalf of the Royal College of Paediatrics and Child Health, and the British Cardiovascular Society
Heart 2020 Mar;106(6):411-420. Epub 2019 Dec 16 doi: 10.1136/heartjnl-2019-315925. PMID: 31843876Free PMC Article

Recent clinical studies

Etiology

Acute Coronary Stent Thrombosis in Modern Era: Etiology, Treatment, and Prognosis.
Ge J, Yu H, Li J
Cardiology 2017;137(4):246-255. Epub 2017 May 5 doi: 10.1159/000464404. PMID: 28472800
Stent restenosis and thrombosis: etiology, treatment, and outcomes.
van Buuren F, Dahm JB, Horskotte D
Minerva Med 2012 Dec;103(6):503-11. PMID: 23229369
Thrombosis and acute coronary syndrome.
Abbate R, Cioni G, Ricci I, Miranda M, Gori AM
Thromb Res 2012 Mar;129(3):235-40. Epub 2012 Jan 24 doi: 10.1016/j.thromres.2011.12.026. PMID: 22281070
Exercise and thrombosis.
Imhof A, Koenig W
Cardiol Clin 2001 Aug;19(3):389-400. doi: 10.1016/s0733-8651(05)70224-1. PMID: 11570112
Plaque disruption and coronary thrombosis: new insight into pathogenesis and prevention.
Shah PK
Clin Cardiol 1997 Nov;20(11 Suppl 2):II-38-44. PMID: 9422851

Diagnosis

Acute myocardial infarction.
Barnett R
Lancet 2019 Jun 29;393(10191):2580. Epub 2019 Jun 27 doi: 10.1016/S0140-6736(19)31419-9. PMID: 31258118
Evaluation of thrombotic left main coronary artery occlusions; old problem, different treatment approaches.
Akcay M
Indian Heart J 2018 Jul-Aug;70(4):573-574. Epub 2017 Sep 14 doi: 10.1016/j.ihj.2017.09.006. PMID: 30170655Free PMC Article
Stent thrombosis: a clinical perspective.
Claessen BE, Henriques JP, Jaffer FA, Mehran R, Piek JJ, Dangas GD
JACC Cardiovasc Interv 2014 Oct;7(10):1081-92. doi: 10.1016/j.jcin.2014.05.016. PMID: 25341705
Intracoronary thrombus.
Achenbach S, Marwan M
J Cardiovasc Comput Tomogr 2009 Sep-Oct;3(5):344-5. Epub 2009 Jun 21 doi: 10.1016/j.jcct.2009.06.009. PMID: 19643694
Plaque disruption and coronary thrombosis: new insight into pathogenesis and prevention.
Shah PK
Clin Cardiol 1997 Nov;20(11 Suppl 2):II-38-44. PMID: 9422851

Therapy

Stent thrombosis and optimal duration of dual antiplatelet therapy after coronary stenting in contemporary practice.
Cho MS, Park DW
Korean J Intern Med 2017 Sep;32(5):769-779. Epub 2017 Aug 22 doi: 10.3904/kjim.2016.391. PMID: 28823143Free PMC Article
Updates on Acute Coronary Syndrome: A Review.
Eisen A, Giugliano RP, Braunwald E
JAMA Cardiol 2016 Sep 1;1(6):718-30. doi: 10.1001/jamacardio.2016.2049. PMID: 27438381
Platelet-Mediated Thrombosis: From Bench to Bedside.
Gurbel PA, Jeong YH, Navarese EP, Tantry US
Circ Res 2016 Apr 29;118(9):1380-91. doi: 10.1161/CIRCRESAHA.115.307016. PMID: 27126648
Novel oral anticoagulants in acute coronary syndrome.
Costopoulos C, Niespialowska-Steuden M, Kukreja N, Gorog DA
Int J Cardiol 2013 Sep 10;167(6):2449-55. Epub 2012 Sep 16 doi: 10.1016/j.ijcard.2012.08.014. PMID: 22989603
Clinical pharmacology of bivalirudin.
Reed MD, Bell D
Pharmacotherapy 2002 Jun;22(6 Pt 2):105S-111S. doi: 10.1592/phco.22.10.105s.33616. PMID: 12064567

Prognosis

SPONTANEOUS CORONARY ARTERY DISSECTION.
Jonjev Ž
Med Pregl 2015 Sep-Oct;68(9-10):337-40. doi: 10.2298/mpns1510337j. PMID: 26727831
Very late stent thrombosis: current concepts.
Siddiqi OK, Faxon DP
Curr Opin Cardiol 2012 Nov;27(6):634-41. doi: 10.1097/HCO.0b013e3283587c7e. PMID: 23075822
Covered stents: a review.
Jamshidi P, Mahmoody K, Erne P
Int J Cardiol 2008 Nov 28;130(3):310-8. Epub 2008 Jul 30 doi: 10.1016/j.ijcard.2008.04.083. PMID: 18672301
Drug-eluting stent thrombosis.
Steinberg DH, Satler LF
Minerva Cardioangiol 2008 Feb;56(1):127-37. PMID: 18432175
Exercise and thrombosis.
Imhof A, Koenig W
Cardiol Clin 2001 Aug;19(3):389-400. doi: 10.1016/s0733-8651(05)70224-1. PMID: 11570112

Clinical prediction guides

Noninvasive In Vivo Coronary Artery Thrombus Imaging.
Tzolos E, Bing R, Andrews J, MacAskill MG, Tavares AAS, Macnaught G, Clark T, Mills NL, Fujisawa T, Nash J, Dey D, Slomka PJ, Koglin N, Stephens AW, Deutsch MA, van Beek EJR, Williams MC, Hermann S, Hugenberg V, Dweck MR, Newby DE
JACC Cardiovasc Imaging 2023 Jun;16(6):820-832. Epub 2022 Dec 14 doi: 10.1016/j.jcmg.2022.10.002. PMID: 36526577
Diagnosis of coronary microvascular dysfunction in the clinic.
Ong P, Safdar B, Seitz A, Hubert A, Beltrame JF, Prescott E
Cardiovasc Res 2020 Mar 1;116(4):841-855. doi: 10.1093/cvr/cvz339. PMID: 31904824
Updated Expert Consensus Statement on Platelet Function and Genetic Testing for Guiding P2Y(12) Receptor Inhibitor Treatment in Percutaneous Coronary Intervention.
Sibbing D, Aradi D, Alexopoulos D, Ten Berg J, Bhatt DL, Bonello L, Collet JP, Cuisset T, Franchi F, Gross L, Gurbel P, Jeong YH, Mehran R, Moliterno DJ, Neumann FJ, Pereira NL, Price MJ, Sabatine MS, So DYF, Stone GW, Storey RF, Tantry U, Trenk D, Valgimigli M, Waksman R, Angiolillo DJ
JACC Cardiovasc Interv 2019 Aug 26;12(16):1521-1537. Epub 2019 Jun 12 doi: 10.1016/j.jcin.2019.03.034. PMID: 31202949
Stent thrombosis: a clinical perspective.
Claessen BE, Henriques JP, Jaffer FA, Mehran R, Piek JJ, Dangas GD
JACC Cardiovasc Interv 2014 Oct;7(10):1081-92. doi: 10.1016/j.jcin.2014.05.016. PMID: 25341705
Vulnerable plaque imaging-current techniques.
Hilty KC, Steinberg DH
J Cardiovasc Transl Res 2009 Mar;2(1):9-18. Epub 2009 Jan 14 doi: 10.1007/s12265-008-9086-1. PMID: 20559964

Recent systematic reviews

Adverse events following COVID-19 mRNA vaccines: A systematic review of cardiovascular complication, thrombosis, and thrombocytopenia.
Yasmin F, Najeeb H, Naeem U, Moeed A, Atif AR, Asghar MS, Nimri N, Saleem M, Bandyopadhyay D, Krittanawong C, Fadelallah Eljack MM, Tahir MJ, Waqar F
Immun Inflamm Dis 2023 Mar;11(3):e807. doi: 10.1002/iid3.807. PMID: 36988252Free PMC Article
Coronary Stent Thrombosis in COVID-19 Patients: A Systematic Review of Cases Reported Worldwide.
Skorupski WJ, Grygier M, Lesiak M, Kałużna-Oleksy M
Viruses 2022 Jan 27;14(2) doi: 10.3390/v14020260. PMID: 35215853Free PMC Article
Non-vitamin K antagonist oral anticoagulants for the treatment of intracardiac thrombosis.
Ghaffarpasand E, Tehrani MD, Marszalek J, Chi G
J Thromb Thrombolysis 2018 Oct;46(3):332-338. doi: 10.1007/s11239-018-1693-3. PMID: 29876713
Very Late Scaffold Thrombosis of Bioresorbable Vascular Scaffold: Systematic Review and a Meta-Analysis.
Toyota T, Morimoto T, Shiomi H, Yoshikawa Y, Yaku H, Yamashita Y, Kimura T
JACC Cardiovasc Interv 2017 Jan 9;10(1):27-37. doi: 10.1016/j.jcin.2016.10.027. PMID: 28057284
Stent Thrombosis With Drug-Eluting Stents and Bioresorbable Scaffolds: Evidence From a Network Meta-Analysis of 147 Trials.
Kang SH, Chae IH, Park JJ, Lee HS, Kang DY, Hwang SS, Youn TJ, Kim HS
JACC Cardiovasc Interv 2016 Jun 27;9(12):1203-1212. Epub 2016 Jun 1 doi: 10.1016/j.jcin.2016.03.038. PMID: 27262860

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