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Cloudman S91 Malignant Melanoma

MedGen UID:
1011
•Concept ID:
C0009075
•
Experimental Model of Disease; Neoplastic Process
Synonyms: Cloudman S91 Melanoma; Melanoma, Cloudman S91; S91 Melanoma, Cloudman

Definition

A transplantable melanoma that arose spontaneously in a mouse of DBA strain, and which grows and metastasizes in mice of related strains. (dictionarybarn.com) [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCloudman S91 Malignant Melanoma

Professional guidelines

PubMed

The Use of Retinoids for the Prevention and Treatment of Skin Cancers: An Updated Review.
Ramchatesingh B, Martínez Villarreal A, Arcuri D, Lagacé F, Setah SA, Touma F, Al-Badarin F, Litvinov IV
Int J Mol Sci 2022 Oct 20;23(20) doi: 10.3390/ijms232012622. PMID: 36293471Free PMC Article
Drug-induced interstitial lung disease during cancer therapies: expert opinion on diagnosis and treatment.
Conte P, Ascierto PA, Patelli G, Danesi R, Vanzulli A, Sandomenico F, Tarsia P, Cattelan A, Comes A, De Laurentiis M, Falcone A, Regge D, Richeldi L, Siena S
ESMO Open 2022 Apr;7(2):100404. Epub 2022 Feb 24 doi: 10.1016/j.esmoop.2022.100404. PMID: 35219244Free PMC Article
Novel Peptide Therapeutic Approaches for Cancer Treatment.
Li CM, Haratipour P, Lingeman RG, Perry JJP, Gu L, Hickey RJ, Malkas LH
Cells 2021 Oct 27;10(11) doi: 10.3390/cells10112908. PMID: 34831131Free PMC Article

Recent clinical studies

Etiology

Dietary fiber and probiotics influence the gut microbiome and melanoma immunotherapy response.
Spencer CN, McQuade JL, Gopalakrishnan V, McCulloch JA, Vetizou M, Cogdill AP, Khan MAW, Zhang X, White MG, Peterson CB, Wong MC, Morad G, Rodgers T, Badger JH, Helmink BA, Andrews MC, Rodrigues RR, Morgun A, Kim YS, Roszik J, Hoffman KL, Zheng J, Zhou Y, Medik YB, Kahn LM, Johnson S, Hudgens CW, Wani K, Gaudreau PO, Harris AL, Jamal MA, Baruch EN, Perez-Guijarro E, Day CP, Merlino G, Pazdrak B, Lochmann BS, Szczepaniak-Sloane RA, Arora R, Anderson J, Zobniw CM, Posada E, Sirmans E, Simon J, Haydu LE, Burton EM, Wang L, Dang M, Clise-Dwyer K, Schneider S, Chapman T, Anang NAS, Duncan S, Toker J, Malke JC, Glitza IC, Amaria RN, Tawbi HA, Diab A, Wong MK, Patel SP, Woodman SE, Davies MA, Ross MI, Gershenwald JE, Lee JE, Hwu P, Jensen V, Samuels Y, Straussman R, Ajami NJ, Nelson KC, Nezi L, Petrosino JF, Futreal PA, Lazar AJ, Hu J, Jenq RR, Tetzlaff MT, Yan Y, Garrett WS, Huttenhower C, Sharma P, Watowich SS, Allison JP, Cohen L, Trinchieri G, Daniel CR, Wargo JA
Science 2021 Dec 24;374(6575):1632-1640. Epub 2021 Dec 23 doi: 10.1126/science.aaz7015. PMID: 34941392Free PMC Article
Delivery of mRNA vaccine with a lipid-like material potentiates antitumor efficacy through Toll-like receptor 4 signaling.
Zhang H, You X, Wang X, Cui L, Wang Z, Xu F, Li M, Yang Z, Liu J, Huang P, Kang Y, Wu J, Xia X
Proc Natl Acad Sci U S A 2021 Feb 9;118(6) doi: 10.1073/pnas.2005191118. PMID: 33547233Free PMC Article
NR4A transcription factors limit CAR T cell function in solid tumours.
Chen J, López-Moyado IF, Seo H, Lio CJ, Hempleman LJ, Sekiya T, Yoshimura A, Scott-Browne JP, Rao A
Nature 2019 Mar;567(7749):530-534. Epub 2019 Feb 27 doi: 10.1038/s41586-019-0985-x. PMID: 30814732Free PMC Article
Antibody-mediated inhibition of MICA and MICB shedding promotes NK cell-driven tumor immunity.
Ferrari de Andrade L, Tay RE, Pan D, Luoma AM, Ito Y, Badrinath S, Tsoucas D, Franz B, May KF Jr, Harvey CJ, Kobold S, Pyrdol JW, Yoon C, Yuan GC, Hodi FS, Dranoff G, Wucherpfennig KW
Science 2018 Mar 30;359(6383):1537-1542. doi: 10.1126/science.aao0505. PMID: 29599246Free PMC Article
Oral melanoma and other pigmentations: when to biopsy?
Lambertini M, Patrizi A, Fanti PA, Melotti B, Caliceti U, Magnoni C, Misciali C, Baraldi C, Ravaioli GM, Dika E
J Eur Acad Dermatol Venereol 2018 Feb;32(2):209-214. Epub 2017 Sep 14 doi: 10.1111/jdv.14574. PMID: 28862771

Diagnosis

Mitochondrial Lon-induced mtDNA leakage contributes to PD-L1-mediated immunoescape via STING-IFN signaling and extracellular vesicles.
Cheng AN, Cheng LC, Kuo CL, Lo YK, Chou HY, Chen CH, Wang YH, Chuang TH, Cheng SJ, Lee AY
J Immunother Cancer 2020 Dec;8(2) doi: 10.1136/jitc-2020-001372. PMID: 33268351Free PMC Article
Neuropilin-1 is a T cell memory checkpoint limiting long-term antitumor immunity.
Liu C, Somasundaram A, Manne S, Gocher AM, Szymczak-Workman AL, Vignali KM, Scott EN, Normolle DP, John Wherry E, Lipson EJ, Ferris RL, Bruno TC, Workman CJ, Vignali DAA
Nat Immunol 2020 Sep;21(9):1010-1021. Epub 2020 Jul 13 doi: 10.1038/s41590-020-0733-2. PMID: 32661362Free PMC Article
Estrogen Receptors and Melanoma: A Review.
Dika E, Patrizi A, Lambertini M, Manuelpillai N, Fiorentino M, Altimari A, Ferracin M, Lauriola M, Fabbri E, Campione E, Veronesi G, Scarfì F
Cells 2019 Nov 19;8(11) doi: 10.3390/cells8111463. PMID: 31752344Free PMC Article
Malignant Melanoma Cells and Hair Follicles.
Dika E, Veronesi G, Misciali C, Corti B, Dika I, Riefolo M, Scarfì F, Lambertini M, Patrizi A
Am J Clin Pathol 2019 Jun 5;152(1):109-114. doi: 10.1093/ajcp/aqz029. PMID: 31165166
A major chromatin regulator determines resistance of tumor cells to T cell-mediated killing.
Pan D, Kobayashi A, Jiang P, Ferrari de Andrade L, Tay RE, Luoma AM, Tsoucas D, Qiu X, Lim K, Rao P, Long HW, Yuan GC, Doench J, Brown M, Liu XS, Wucherpfennig KW
Science 2018 Feb 16;359(6377):770-775. Epub 2018 Jan 4 doi: 10.1126/science.aao1710. PMID: 29301958Free PMC Article

Therapy

Manganese is critical for antitumor immune responses via cGAS-STING and improves the efficacy of clinical immunotherapy.
Lv M, Chen M, Zhang R, Zhang W, Wang C, Zhang Y, Wei X, Guan Y, Liu J, Feng K, Jing M, Wang X, Liu YC, Mei Q, Han W, Jiang Z
Cell Res 2020 Nov;30(11):966-979. Epub 2020 Aug 24 doi: 10.1038/s41422-020-00395-4. PMID: 32839553Free PMC Article
Built-In Active Microneedle Patch with Enhanced Autonomous Drug Delivery.
Lopez-Ramirez MA, Soto F, Wang C, Rueda R, Shukla S, Silva-Lopez C, Kupor D, McBride DA, Pokorski JK, Nourhani A, Steinmetz NF, Shah NJ, Wang J
Adv Mater 2020 Jan;32(1):e1905740. Epub 2019 Nov 4 doi: 10.1002/adma.201905740. PMID: 31682039Free PMC Article
Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response.
Jiang P, Gu S, Pan D, Fu J, Sahu A, Hu X, Li Z, Traugh N, Bu X, Li B, Liu J, Freeman GJ, Brown MA, Wucherpfennig KW, Liu XS
Nat Med 2018 Oct;24(10):1550-1558. Epub 2018 Aug 20 doi: 10.1038/s41591-018-0136-1. PMID: 30127393Free PMC Article
A major chromatin regulator determines resistance of tumor cells to T cell-mediated killing.
Pan D, Kobayashi A, Jiang P, Ferrari de Andrade L, Tay RE, Luoma AM, Tsoucas D, Qiu X, Lim K, Rao P, Long HW, Yuan GC, Doench J, Brown M, Liu XS, Wucherpfennig KW
Science 2018 Feb 16;359(6377):770-775. Epub 2018 Jan 4 doi: 10.1126/science.aao1710. PMID: 29301958Free PMC Article
Lipid Nanoparticle Assisted mRNA Delivery for Potent Cancer Immunotherapy.
Oberli MA, Reichmuth AM, Dorkin JR, Mitchell MJ, Fenton OS, Jaklenec A, Anderson DG, Langer R, Blankschtein D
Nano Lett 2017 Mar 8;17(3):1326-1335. Epub 2016 Dec 5 doi: 10.1021/acs.nanolett.6b03329. PMID: 28273716Free PMC Article

Prognosis

Nociceptor neurons affect cancer immunosurveillance.
Balood M, Ahmadi M, Eichwald T, Ahmadi A, Majdoubi A, Roversi K, Roversi K, Lucido CT, Restaino AC, Huang S, Ji L, Huang KC, Semerena E, Thomas SC, Trevino AE, Merrison H, Parrin A, Doyle B, Vermeer DW, Spanos WC, Williamson CS, Seehus CR, Foster SL, Dai H, Shu CJ, Rangachari M, Thibodeau J, V Del Rincon S, Drapkin R, Rafei M, Ghasemlou N, Vermeer PD, Woolf CJ, Talbot S
Nature 2022 Nov;611(7935):405-412. Epub 2022 Nov 2 doi: 10.1038/s41586-022-05374-w. PMID: 36323780Free PMC Article
CD36-mediated ferroptosis dampens intratumoral CD8(+) T cell effector function and impairs their antitumor ability.
Ma X, Xiao L, Liu L, Ye L, Su P, Bi E, Wang Q, Yang M, Qian J, Yi Q
Cell Metab 2021 May 4;33(5):1001-1012.e5. Epub 2021 Mar 9 doi: 10.1016/j.cmet.2021.02.015. PMID: 33691090Free PMC Article
NR4A transcription factors limit CAR T cell function in solid tumours.
Chen J, López-Moyado IF, Seo H, Lio CJ, Hempleman LJ, Sekiya T, Yoshimura A, Scott-Browne JP, Rao A
Nature 2019 Mar;567(7749):530-534. Epub 2019 Feb 27 doi: 10.1038/s41586-019-0985-x. PMID: 30814732Free PMC Article
Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response.
Jiang P, Gu S, Pan D, Fu J, Sahu A, Hu X, Li Z, Traugh N, Bu X, Li B, Liu J, Freeman GJ, Brown MA, Wucherpfennig KW, Liu XS
Nat Med 2018 Oct;24(10):1550-1558. Epub 2018 Aug 20 doi: 10.1038/s41591-018-0136-1. PMID: 30127393Free PMC Article
Interferon-γ Drives T(reg) Fragility to Promote Anti-tumor Immunity.
Overacre-Delgoffe AE, Chikina M, Dadey RE, Yano H, Brunazzi EA, Shayan G, Horne W, Moskovitz JM, Kolls JK, Sander C, Shuai Y, Normolle DP, Kirkwood JM, Ferris RL, Delgoffe GM, Bruno TC, Workman CJ, Vignali DAA
Cell 2017 Jun 1;169(6):1130-1141.e11. Epub 2017 May 25 doi: 10.1016/j.cell.2017.05.005. PMID: 28552348Free PMC Article

Clinical prediction guides

Dietary fiber and probiotics influence the gut microbiome and melanoma immunotherapy response.
Spencer CN, McQuade JL, Gopalakrishnan V, McCulloch JA, Vetizou M, Cogdill AP, Khan MAW, Zhang X, White MG, Peterson CB, Wong MC, Morad G, Rodgers T, Badger JH, Helmink BA, Andrews MC, Rodrigues RR, Morgun A, Kim YS, Roszik J, Hoffman KL, Zheng J, Zhou Y, Medik YB, Kahn LM, Johnson S, Hudgens CW, Wani K, Gaudreau PO, Harris AL, Jamal MA, Baruch EN, Perez-Guijarro E, Day CP, Merlino G, Pazdrak B, Lochmann BS, Szczepaniak-Sloane RA, Arora R, Anderson J, Zobniw CM, Posada E, Sirmans E, Simon J, Haydu LE, Burton EM, Wang L, Dang M, Clise-Dwyer K, Schneider S, Chapman T, Anang NAS, Duncan S, Toker J, Malke JC, Glitza IC, Amaria RN, Tawbi HA, Diab A, Wong MK, Patel SP, Woodman SE, Davies MA, Ross MI, Gershenwald JE, Lee JE, Hwu P, Jensen V, Samuels Y, Straussman R, Ajami NJ, Nelson KC, Nezi L, Petrosino JF, Futreal PA, Lazar AJ, Hu J, Jenq RR, Tetzlaff MT, Yan Y, Garrett WS, Huttenhower C, Sharma P, Watowich SS, Allison JP, Cohen L, Trinchieri G, Daniel CR, Wargo JA
Science 2021 Dec 24;374(6575):1632-1640. Epub 2021 Dec 23 doi: 10.1126/science.aaz7015. PMID: 34941392Free PMC Article
IL-2 regulates tumor-reactive CD8(+) T cell exhaustion by activating the aryl hydrocarbon receptor.
Liu Y, Zhou N, Zhou L, Wang J, Zhou Y, Zhang T, Fang Y, Deng J, Gao Y, Liang X, Lv J, Wang Z, Xie J, Xue Y, Zhang H, Ma J, Tang K, Fang Y, Cheng F, Zhang C, Dong B, Zhao Y, Yuan P, Gao Q, Zhang H, Xiao-Feng Qin F, Huang B
Nat Immunol 2021 Mar;22(3):358-369. Epub 2021 Jan 11 doi: 10.1038/s41590-020-00850-9. PMID: 33432230
Tumor suppressor TET2 promotes cancer immunity and immunotherapy efficacy.
Xu YP, Lv L, Liu Y, Smith MD, Li WC, Tan XM, Cheng M, Li Z, Bovino M, Aubé J, Xiong Y
J Clin Invest 2019 Jul 16;129(10):4316-4331. doi: 10.1172/JCI129317. PMID: 31310587Free PMC Article
Tumor metastasis to lymph nodes requires YAP-dependent metabolic adaptation.
Lee CK, Jeong SH, Jang C, Bae H, Kim YH, Park I, Kim SK, Koh GY
Science 2019 Feb 8;363(6427):644-649. Epub 2019 Feb 7 doi: 10.1126/science.aav0173. PMID: 30733421
Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response.
Jiang P, Gu S, Pan D, Fu J, Sahu A, Hu X, Li Z, Traugh N, Bu X, Li B, Liu J, Freeman GJ, Brown MA, Wucherpfennig KW, Liu XS
Nat Med 2018 Oct;24(10):1550-1558. Epub 2018 Aug 20 doi: 10.1038/s41591-018-0136-1. PMID: 30127393Free PMC Article

Recent systematic reviews

Melanoma in children: A systematic review and individual patient meta-analysis.
Pampena R, Piccolo V, Muscianese M, Kyrgidis A, Lai M, Russo T, Briatico G, Di Brizzi EV, Cascone G, Pellerone S, Longo C, Moscarella E, Argenziano G
J Eur Acad Dermatol Venereol 2023 Sep;37(9):1758-1776. Epub 2023 Jun 2 doi: 10.1111/jdv.19220. PMID: 37210654
Immune-related adverse events as potential surrogates of immune checkpoint inhibitors' efficacy: a systematic review and meta-analysis of randomized studies.
Amoroso V, Gallo F, Alberti A, Paloschi D, Ferrari Bravo W, Esposito A, Cosentini D, Grisanti S, Pedersini R, Petrelli F, Berruti A
ESMO Open 2023 Apr;8(2):100787. Epub 2023 Feb 24 doi: 10.1016/j.esmoop.2023.100787. PMID: 36842300Free PMC Article
Association between immune-related side effects and efficacy and benefit of immune checkpoint inhibitors - A systematic review and meta-analysis.
Hussaini S, Chehade R, Boldt RG, Raphael J, Blanchette P, Maleki Vareki S, Fernandes R
Cancer Treat Rev 2021 Jan;92:102134. Epub 2020 Dec 3 doi: 10.1016/j.ctrv.2020.102134. PMID: 33302134
Green tea (Camellia sinensis) for the prevention of cancer.
Filippini T, Malavolti M, Borrelli F, Izzo AA, Fairweather-Tait SJ, Horneber M, Vinceti M
Cochrane Database Syst Rev 2020 Mar 2;3(3):CD005004. doi: 10.1002/14651858.CD005004.pub3. PMID: 32118296Free PMC Article
Selenium for preventing cancer.
Vinceti M, Filippini T, Del Giovane C, Dennert G, Zwahlen M, Brinkman M, Zeegers MP, Horneber M, D'Amico R, Crespi CM
Cochrane Database Syst Rev 2018 Jan 29;1(1):CD005195. doi: 10.1002/14651858.CD005195.pub4. PMID: 29376219Free PMC Article

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