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Chlamydial infection

MedGen UID:
40237
•Concept ID:
C0008149
•
Disease or Syndrome
Synonyms: Chlamydia Infection; Chlamydia Infections; Infection, Chlamydia; Infections, Chlamydia
SNOMED CT: Chlamydial infection (105629000)

Definition

An infection that is caused by Chlamydia trachomatis. [from NCI]

Professional guidelines

PubMed

Chlamydia trachomatis Screening and Treatment in Pregnancy to Reduce Adverse Pregnancy and Neonatal Outcomes: A Review.
Adachi KN, Nielsen-Saines K, Klausner JD
Front Public Health 2021;9:531073. Epub 2021 Jun 10 doi: 10.3389/fpubh.2021.531073. PMID: 34178906Free PMC Article
Update to CDC's Treatment Guidelines for Gonococcal Infection, 2020.
St Cyr S, Barbee L, Workowski KA, Bachmann LH, Pham C, Schlanger K, Torrone E, Weinstock H, Kersh EN, Thorpe P
MMWR Morb Mortal Wkly Rep 2020 Dec 18;69(50):1911-1916. doi: 10.15585/mmwr.mm6950a6. PMID: 33332296Free PMC Article
Treatment of Neonatal Chlamydial Conjunctivitis: A Systematic Review and Meta-analysis.
Zikic A, Schünemann H, Wi T, Lincetto O, Broutet N, Santesso N
J Pediatric Infect Dis Soc 2018 Aug 17;7(3):e107-e115. doi: 10.1093/jpids/piy060. PMID: 30007329Free PMC Article

Recent clinical studies

Etiology

Sociodemographic Factors Associated With Gonorrhea and Chlamydia Infection in Pregnancy.
Gulersen M, Lenchner E, Eliner Y, Grunebaum A, Chervenak FA, Bornstein E
Sex Transm Dis 2022 Nov 1;49(11):750-754. Epub 2022 Aug 6 doi: 10.1097/OLQ.0000000000001688. PMID: 35948286
Genital Chlamydia trachomatis and Neisseria gonorrhoeae infections among women in sub-Saharan Africa: A structured review.
Dubbink JH, Verweij SP, Struthers HE, Ouburg S, McIntyre JA, Morré SA, Peters RP
Int J STD AIDS 2018 Jul;29(8):806-824. Epub 2018 Feb 28 doi: 10.1177/0956462418758224. PMID: 29486628
Chlamydial polymorphic membrane proteins: regulation, function and potential vaccine candidates.
Vasilevsky S, Stojanov M, Greub G, Baud D
Virulence 2016;7(1):11-22. Epub 2015 Nov 18 doi: 10.1080/21505594.2015.1111509. PMID: 26580416Free PMC Article
Trachoma and Ocular Chlamydial Infection in the Era of Genomics.
Derrick T, Roberts Ch, Last AR, Burr SE, Holland MJ
Mediators Inflamm 2015;2015:791847. Epub 2015 Sep 3 doi: 10.1155/2015/791847. PMID: 26424969Free PMC Article
Chlamydial infections of the cardiovascular system.
Kuo CC, Campbell LA
Front Biosci 2003 Jan 1;8:e36-43. doi: 10.2741/859. PMID: 12456307

Diagnosis

AAUS guideline for chlamydial urethritis.
Hiyama Y, Takahashi S, Yasuda M
J Infect Chemother 2022 Feb;28(2):142-145. Epub 2021 Dec 7 doi: 10.1016/j.jiac.2021.11.024. PMID: 34887176
Laboratory diagnosis of persistent human chlamydial infection.
Puolakkainen M
Front Cell Infect Microbiol 2013;3:99. Epub 2013 Dec 17 doi: 10.3389/fcimb.2013.00099. PMID: 24381934Free PMC Article
Male genital tract chlamydial infection: implications for pathology and infertility.
Cunningham KA, Beagley KW
Biol Reprod 2008 Aug;79(2):180-9. Epub 2008 May 14 doi: 10.1095/biolreprod.108.067835. PMID: 18480466
Diagnosis and treatment of Chlamydia trachomatis infection.
Miller KE
Am Fam Physician 2006 Apr 15;73(8):1411-6. PMID: 16669564
Chlamydial infections.
Blanchard TJ, Mabey DC
Br J Clin Pract 1994 Jul-Aug;48(4):201-5. PMID: 7917800

Therapy

Update to CDC's Treatment Guidelines for Gonococcal Infection, 2020.
St Cyr S, Barbee L, Workowski KA, Bachmann LH, Pham C, Schlanger K, Torrone E, Weinstock H, Kersh EN, Thorpe P
MMWR Morb Mortal Wkly Rep 2020 Dec 18;69(50):1911-1916. doi: 10.15585/mmwr.mm6950a6. PMID: 33332296Free PMC Article
Gonorrhea, a current disease with ancient roots: from the remedies of the past to future perspectives.
Vicentini CB, Manfredini S, Maritati M, Di Nuzzo M, Contini C
Infez Med 2019 Jun 1;27(2):212-221. PMID: 31205048
Chlamydia (uncomplicated, genital).
Crofts M, Horner P
BMJ Clin Evid 2015 Apr 16;2015 PMID: 25880031Free PMC Article
Vaginal douching.
Cottrell BH
J Obstet Gynecol Neonatal Nurs 2003 Jan-Feb;32(1):12-8. doi: 10.1177/0884217502239796. PMID: 12570177
Gonococcal infections.
Hook EW 3rd, Holmes KK
Ann Intern Med 1985 Feb;102(2):229-43. doi: 10.7326/0003-4819-102-2-229. PMID: 3917638

Prognosis

A Review of the Challenges and Complexities in the Diagnosis, Etiology, Epidemiology, and Pathogenesis of Pelvic Inflammatory Disease.
Hillier SL, Bernstein KT, Aral S
J Infect Dis 2021 Aug 16;224(12 Suppl 2):S23-S28. doi: 10.1093/infdis/jiab116. PMID: 34396398Free PMC Article
Infections caused by Chlamydophila pneumoniae.
Choroszy-Król I, Frej-Mądrzak M, Hober M, Sarowska J, Jama-Kmiecik A
Adv Clin Exp Med 2014 Jan-Feb;23(1):123-6. doi: 10.17219/acem/37035. PMID: 24596014
Abdominal aortic aneurysms.
Lindholt JS
Dan Med Bull 2010 Dec;57(12):B4219. PMID: 21122465
Chlamydial infections.
Blanchard TJ, Mabey DC
Br J Clin Pract 1994 Jul-Aug;48(4):201-5. PMID: 7917800
Chlamydia trachomatis: serological diagnosis.
Treharne JD
Infection 1982;10 Suppl 1:S25-31. doi: 10.1007/BF01640711. PMID: 7044980

Clinical prediction guides

Bacterial sexually transmitted infections.
Buder S, Schöfer H, Meyer T, Bremer V, Kohl PK, Skaletz-Rorowski A, Brockmeyer N
J Dtsch Dermatol Ges 2019 Mar;17(3):287-315. doi: 10.1111/ddg.13804. PMID: 30920748
Perinatal morbidity and mortality associated with chlamydial infection: a meta-analysis study.
Silva MJ, Florêncio GL, Gabiatti JR, Amaral RL, Eleutério Júnior J, Gonçalves AK
Braz J Infect Dis 2011 Nov-Dec;15(6):533-9. doi: 10.1590/s1413-86702011000600006. PMID: 22218511
Chlamydia (uncomplicated, genital).
Horner P
BMJ Clin Evid 2010 Apr 22;2010 PMID: 21718568Free PMC Article
Abdominal aortic aneurysms.
Lindholt JS
Dan Med Bull 2010 Dec;57(12):B4219. PMID: 21122465
Chlamydia trachomatis: serological diagnosis.
Treharne JD
Infection 1982;10 Suppl 1:S25-31. doi: 10.1007/BF01640711. PMID: 7044980

Recent systematic reviews

Cervicovaginal Microbiota Composition in Chlamydia trachomatis Infection: A Systematic Review and Meta-Analysis.
Di Pietro M, Filardo S, Simonelli I, Pasqualetti P, Sessa R
Int J Mol Sci 2022 Aug 23;23(17) doi: 10.3390/ijms23179554. PMID: 36076948Free PMC Article
Treatment of Neonatal Chlamydial Conjunctivitis: A Systematic Review and Meta-analysis.
Zikic A, Schünemann H, Wi T, Lincetto O, Broutet N, Santesso N
J Pediatric Infect Dis Soc 2018 Aug 17;7(3):e107-e115. doi: 10.1093/jpids/piy060. PMID: 30007329Free PMC Article
Chlamydia (uncomplicated, genital).
Crofts M, Horner P
BMJ Clin Evid 2015 Apr 16;2015 PMID: 25880031Free PMC Article
Antibiotics for trachoma.
Evans JR, Solomon AW
Cochrane Database Syst Rev 2011 Mar 16;(3):CD001860. doi: 10.1002/14651858.CD001860.pub3. PMID: 21412875
Chlamydia (uncomplicated, genital).
Horner P
BMJ Clin Evid 2010 Apr 22;2010 PMID: 21718568Free PMC Article

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