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Chronic brain syndrome

MedGen UID:
14213
•Concept ID:
C0006109
•
Disease or Syndrome
Synonyms: Brain Damage, Chronic; Chronic Brain Damage; Chronic Encephalopathy; Encephalopathy, Chronic
SNOMED CT: Chronic brain syndrome (78689005); Chronic encephalopathy (78689005)

Definition

Encephalopathy that is persistent or long-standing in nature. [from NCI]

Professional guidelines

PubMed

Treatment of the aged mentally ill: further unmasking of the effects of a diagnosis of chronic brain syndrome.
Ernst P, Beran B, Badash D, Kosovsky R, Kleinhauz M
J Am Geriatr Soc 1977 Oct;25(10):466-9. doi: 10.1111/j.1532-5415.1977.tb00809.x. PMID: 903547
ESTROGEN TREATMENT OF PATIENTS WITH CHRONIC BRAIN SYNDROME ASSOCIATED WITH CEREBRAL ARTERIOSCLEROSIS.
LEFSHITZ K, KLINE NS
Am J Psychiatry 1965 Sep;122:329-31. doi: 10.1176/ajp.122.3.329. PMID: 14327479
Meprobamatebenactyzine (deprol) in the treatment of chronic brain syndrome, schizophrenia and senility.
PENNINGTON VM
J Am Geriatr Soc 1959 Aug;7(8):656-9. doi: 10.1111/j.1532-5415.1959.tb00962.x. PMID: 13672742

Recent clinical studies

Etiology

Lithium Neurotoxicity Due to Second-Generation Antipsychotics Combined With Lithium: A Systematic Review.
Netto I, Phutane VH, Ravindran B
Prim Care Companion CNS Disord 2019 Jun 20;21(3) doi: 10.4088/PCC.17r02225. PMID: 31237432
Emission tomography in dementia.
Pakrasi S, O'Brien JT
Nucl Med Commun 2005 Mar;26(3):189-96. doi: 10.1097/00006231-200503000-00003. PMID: 15722899
Acute and chronic brain injury in United States National Team soccer players.
Jordan SE, Green GA, Galanty HL, Mandelbaum BR, Jabour BA
Am J Sports Med 1996 Mar-Apr;24(2):205-10. doi: 10.1177/036354659602400216. PMID: 8775122
Pain assessment in the elderly.
Hayes R
Br J Nurs 1995 Nov 9-22;4(20):1199-204. doi: 10.12968/bjon.1995.4.20.1199. PMID: 8696088
Chronic painters' syndrome. Chronic toxic encephalopathy in house painters.
Arlien-Søborg P, Bruhn P, Gyldensted C, Melgaard B
Acta Neurol Scand 1979 Sep;60(3):149-56. PMID: 517113

Diagnosis

Lithium Neurotoxicity Due to Second-Generation Antipsychotics Combined With Lithium: A Systematic Review.
Netto I, Phutane VH, Ravindran B
Prim Care Companion CNS Disord 2019 Jun 20;21(3) doi: 10.4088/PCC.17r02225. PMID: 31237432
Emission tomography in dementia.
Pakrasi S, O'Brien JT
Nucl Med Commun 2005 Mar;26(3):189-96. doi: 10.1097/00006231-200503000-00003. PMID: 15722899
Pain assessment in the elderly.
Hayes R
Br J Nurs 1995 Nov 9-22;4(20):1199-204. doi: 10.12968/bjon.1995.4.20.1199. PMID: 8696088
Developmental and family effects of autism.
Levitas A
Pediatr Ann 1990 Jan;19(1):52-8. doi: 10.3928/0090-4481-19900101-09. PMID: 1689020
Chronic brain syndrome reconsidered.
Rogers RC, Ferretti SM, Erdman WJ
Bol Asoc Med P R 1982 Sep;74(9):265-7. PMID: 6963916

Therapy

Lithium Neurotoxicity Due to Second-Generation Antipsychotics Combined With Lithium: A Systematic Review.
Netto I, Phutane VH, Ravindran B
Prim Care Companion CNS Disord 2019 Jun 20;21(3) doi: 10.4088/PCC.17r02225. PMID: 31237432
On the effects of pyritinol on functional deficits of patients with organic mental disorders.
Herrmann WM, Kern U, Röhmel J
Pharmacopsychiatry 1986 Sep;19(5):378-85. doi: 10.1055/s-2007-1017274. PMID: 3534901
Endosulfan poisoning and chronic brain syndrome.
Aleksandrowicz DR
Arch Toxicol 1979 Oct;43(1):65-8. doi: 10.1007/BF00695875. PMID: 533363
Chronic painters' syndrome. Chronic toxic encephalopathy in house painters.
Arlien-Søborg P, Bruhn P, Gyldensted C, Melgaard B
Acta Neurol Scand 1979 Sep;60(3):149-56. PMID: 517113
Serentil for chronic brain syndrome.
Med Lett Drugs Ther 1975 Aug 1;17(16):68. PMID: 1152819

Prognosis

Developmental and family effects of autism.
Levitas A
Pediatr Ann 1990 Jan;19(1):52-8. doi: 10.3928/0090-4481-19900101-09. PMID: 1689020
On the effects of pyritinol on functional deficits of patients with organic mental disorders.
Herrmann WM, Kern U, Röhmel J
Pharmacopsychiatry 1986 Sep;19(5):378-85. doi: 10.1055/s-2007-1017274. PMID: 3534901
Prognosis in chronic toxic encephalopathy. A two-year follow-up study in 26 house painters with occupational encephalopathy.
Bruhn P, Arlien-Søborg P, Gyldensted C, Christensen EL
Acta Neurol Scand 1981 Oct;64(4):259-72. PMID: 7315195
Behavioral change in the chronicity pattern of dementia in the institutional geriatric resident.
Katz MM
J Am Geriatr Soc 1976 Nov;24(11):522-8. doi: 10.1111/j.1532-5415.1976.tb03276.x. PMID: 972239
Changing diagnosis of childhood psychosis.
Piggott LR, Simson CB
J Autism Child Schizophr 1975 Sep;5(3):239-45. doi: 10.1007/BF01538154. PMID: 1174126

Clinical prediction guides

On the effects of pyritinol on functional deficits of patients with organic mental disorders.
Herrmann WM, Kern U, Röhmel J
Pharmacopsychiatry 1986 Sep;19(5):378-85. doi: 10.1055/s-2007-1017274. PMID: 3534901
Contribution to the search for vigilance-indicative EEG variables. Results of a controlled, double-blind study with pyritinol in elderly patients with symptoms of mental dysfunction.
Herrmann WM, Kern U, Röhmel J
Pharmacopsychiatry 1986 Mar;19(2):75-83. doi: 10.1055/s-2007-1017159. PMID: 3517890
Continuous reaction time in patients with hepatic encephalopathy. A quantitative measure of changes in consciousness.
Elsass P, Christensen SE, Ranek L, Theilgaard A, Tygstrup N
Scand J Gastroenterol 1981 Apr;16(3):441-7. doi: 10.3109/00365528109181995. PMID: 16435490
Prognosis in chronic toxic encephalopathy. A two-year follow-up study in 26 house painters with occupational encephalopathy.
Bruhn P, Arlien-Søborg P, Gyldensted C, Christensen EL
Acta Neurol Scand 1981 Oct;64(4):259-72. PMID: 7315195
Mortality of the aged with chronic brain syndrome: further observations in a five-year study.
Peck A, Wolloch L, Rodstein M
J Am Geriatr Soc 1978 Apr;26(4):170-6. doi: 10.1111/j.1532-5415.1978.tb05046.x. PMID: 416066

Recent systematic reviews

Lithium Neurotoxicity Due to Second-Generation Antipsychotics Combined With Lithium: A Systematic Review.
Netto I, Phutane VH, Ravindran B
Prim Care Companion CNS Disord 2019 Jun 20;21(3) doi: 10.4088/PCC.17r02225. PMID: 31237432

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