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Arthus reaction

MedGen UID:
2458
•Concept ID:
C0003907
•
Disease or Syndrome
Synonyms: Arthus Phenomenon; Arthus Reaction; Phenomenon, Arthus; Reaction, Arthus
SNOMED CT: Arthus type urticaria (402413008); Arthus reaction (402413008); Arthus reaction, function (29548007); Arthus reaction (29548007)
 
Monarch Initiative: MONDO:0006660

Definition

A localized vasculitis resulting from deposition of antibody-antigen complexes. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVArthus reaction

Professional guidelines

PubMed

Adverse skin reactions to low molecular weight heparins: frequency, management and prevention.
Wütschert R, Piletta P, Bounameaux H
Drug Saf 1999 Jun;20(6):515-25. doi: 10.2165/00002018-199920060-00005. PMID: 10392668

Recent clinical studies

Therapy

Preclinical Efficacy and Anti-Inflammatory Mechanisms of Action of the Bruton Tyrosine Kinase Inhibitor Rilzabrutinib for Immune-Mediated Disease.
Langrish CL, Bradshaw JM, Francesco MR, Owens TD, Xing Y, Shu J, LaStant J, Bisconte A, Outerbridge C, White SD, Hill RJ, Brameld KA, Goldstein DM, Nunn PA
J Immunol 2021 Apr 1;206(7):1454-1468. Epub 2021 Mar 5 doi: 10.4049/jimmunol.2001130. PMID: 33674445Free PMC Article
The vaccines-associated Arthus reaction.
Peng B, Wei M, Zhu FC, Li JX
Hum Vaccin Immunother 2019;15(11):2769-2777. Epub 2019 May 3 doi: 10.1080/21645515.2019.1602435. PMID: 30945978Free PMC Article
Arthus Reaction.
Wang MH, Hu A, Lee YS, Lai CC
J Emerg Med 2019 Apr;56(4):450-451. Epub 2019 Feb 27 doi: 10.1016/j.jemermed.2018.12.047. PMID: 30826085
Immune complex disease.
Carter PM
Ann Rheum Dis 1973 May;32(3):265-71. doi: 10.1136/ard.32.3.265. PMID: 4146024Free PMC Article
Hypersensitivity.
Turk JL
Scott Med J 1971 Jun;16(6):273-9. doi: 10.1177/003693307101600601. PMID: 4103763

Prognosis

Sex differences in injection site reactions with human vaccines.
Cook IF
Hum Vaccin 2009 Jul;5(7):441-9. Epub 2009 Jul 18 doi: 10.4161/hv.8476. PMID: 19377279
Vaccine allergy and pseudo-allergy.
Ponvert C, Scheinmann P
Eur J Dermatol 2003 Jan-Feb;13(1):10-5. PMID: 12609774
Atypical measles syndrome: pathologic and serologic findings.
Annunziato D, Kaplan MH, Hall WW, Ichinose H, Lin JH, Balsam D, Paladino VS
Pediatrics 1982 Aug;70(2):203-9. PMID: 7099785
Prostaglandins. Their potential in clinical medicine.
Zurier RB
Postgrad Med 1980 Sep;68(3):70-81. doi: 10.1080/00325481.1980.11715530. PMID: 7433293
Immunologic evaluation of patients with cancer by delayed hypersensitivity reactions.
Burdick JF, Wells SA Jr, Herberman RB
Surg Gynecol Obstet 1975 Nov;141(5):779-94. PMID: 128144

Clinical prediction guides

Preclinical Mechanisms of Topical PRN473, a Bruton Tyrosine Kinase Inhibitor, in Immune-Mediated Skin Disease Models.
Xing Y, Chu KA, Wadhwa J, Chen W, Zhu J, Bradshaw JM, Shu J, Foulke MC, Loewenstein N, Nunn P, By K, Phiasivongsa P, Goldstein DM, Langrish CL
Immunohorizons 2021 Jul 29;5(7):581-589. doi: 10.4049/immunohorizons.2100063. PMID: 34326199
Preclinical Efficacy and Anti-Inflammatory Mechanisms of Action of the Bruton Tyrosine Kinase Inhibitor Rilzabrutinib for Immune-Mediated Disease.
Langrish CL, Bradshaw JM, Francesco MR, Owens TD, Xing Y, Shu J, LaStant J, Bisconte A, Outerbridge C, White SD, Hill RJ, Brameld KA, Goldstein DM, Nunn PA
J Immunol 2021 Apr 1;206(7):1454-1468. Epub 2021 Mar 5 doi: 10.4049/jimmunol.2001130. PMID: 33674445Free PMC Article
The vaccines-associated Arthus reaction.
Peng B, Wei M, Zhu FC, Li JX
Hum Vaccin Immunother 2019;15(11):2769-2777. Epub 2019 May 3 doi: 10.1080/21645515.2019.1602435. PMID: 30945978Free PMC Article
Sex differences in injection site reactions with human vaccines.
Cook IF
Hum Vaccin 2009 Jul;5(7):441-9. Epub 2009 Jul 18 doi: 10.4161/hv.8476. PMID: 19377279
Pathology of inflammatory demyelinating neuropathies.
Prineas JW
Baillieres Clin Neurol 1994 Apr;3(1):1-24. PMID: 7921584

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