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Arthus reaction

MedGen UID:: 2458
•Concept ID:: C0003907
•: Disease or Syndrome

Synonyms:	Arthus Phenomenon; Arthus Reaction; Phenomenon, Arthus; Reaction, Arthus
SNOMED CT:	Arthus type urticaria (402413008); Arthus reaction (402413008); Arthus reaction, function (29548007); Arthus reaction (29548007)

Monarch Initiative:	MONDO:0006660

Definition

A localized vasculitis resulting from deposition of antibody-antigen complexes. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVArthus reaction

Disease
- Disorder by Site
  - Immune System and Related Disorders
    - Immune system disorder
      - Allergy
        IgE-mediated allergic disorder
        Arthus reaction

Professional guidelines

PubMed

Adverse skin reactions to low molecular weight heparins: frequency, management and prevention.

Wütschert R, Piletta P, Bounameaux H
Drug Saf 1999 Jun;20(6):515-25. doi: 10.2165/00002018-199920060-00005. PMID: 10392668

See all (1)

Recent clinical studies

Etiology

Immunostimulatory and anti-allergic potential of novel heterotrimeric lectin from seeds of Zizyphus mauritiana Lam.

Butle AB, Talmale SA, Jadhao VV, Patil MB, Lambat TL
Int J Biol Macromol 2021 Feb 28;171:389-397. Epub 2021 Jan 9 doi: 10.1016/j.ijbiomac.2021.01.027. PMID: 33428960

The vaccines-associated Arthus reaction.

Peng B, Wei M, Zhu FC, Li JX
Hum Vaccin Immunother 2019;15(11):2769-2777. Epub 2019 May 3 doi: 10.1080/21645515.2019.1602435. PMID: 30945978 Free PMC Article

Sex differences in injection site reactions with human vaccines.

Cook IF
Hum Vaccin 2009 Jul;5(7):441-9. Epub 2009 Jul 18 doi: 10.4161/hv.8476. PMID: 19377279

Intravascular coagulation and osteonecrosis.

Jones JP Jr
Clin Orthop Relat Res 1992 Apr;(277):41-53. PMID: 1532547

Serendipity in immunology.

Humphrey JH
Annu Rev Immunol 1984;2:1-21. doi: 10.1146/annurev.iy.02.040184.000245. PMID: 6100472

See all (29)

Diagnosis

The vaccines-associated Arthus reaction.

Peng B, Wei M, Zhu FC, Li JX
Hum Vaccin Immunother 2019;15(11):2769-2777. Epub 2019 May 3 doi: 10.1080/21645515.2019.1602435. PMID: 30945978 Free PMC Article

Sex differences in injection site reactions with human vaccines.

Cook IF
Hum Vaccin 2009 Jul;5(7):441-9. Epub 2009 Jul 18 doi: 10.4161/hv.8476. PMID: 19377279

Immunopatholgenesis of hypersensitivity pneumonitis.

Schatz M, Patterson R, Fink J
J Allergy Clin Immunol 1977 Jul;60(1):27-37. doi: 10.1016/0091-6749(77)90079-3. PMID: 141470

Hypersensitivity pneumonitis.

Feldman G, Gordon VH
South Med J 1975 Aug;68(8):952-7. doi: 10.1097/00007611-197508000-00006. PMID: 125924

Allergy and drug sensitivity of skin.

Demis DJ
Annu Rev Pharmacol 1969;9:457-82. doi: 10.1146/annurev.pa.09.040169.002325. PMID: 4239726

See all (70)

Therapy

Preclinical Efficacy and Anti-Inflammatory Mechanisms of Action of the Bruton Tyrosine Kinase Inhibitor Rilzabrutinib for Immune-Mediated Disease.

Langrish CL, Bradshaw JM, Francesco MR, Owens TD, Xing Y, Shu J, LaStant J, Bisconte A, Outerbridge C, White SD, Hill RJ, Brameld KA, Goldstein DM, Nunn PA
J Immunol 2021 Apr 1;206(7):1454-1468. Epub 2021 Mar 5 doi: 10.4049/jimmunol.2001130. PMID: 33674445 Free PMC Article

The vaccines-associated Arthus reaction.

Peng B, Wei M, Zhu FC, Li JX
Hum Vaccin Immunother 2019;15(11):2769-2777. Epub 2019 May 3 doi: 10.1080/21645515.2019.1602435. PMID: 30945978 Free PMC Article

Arthus Reaction.

Wang MH, Hu A, Lee YS, Lai CC
J Emerg Med 2019 Apr;56(4):450-451. Epub 2019 Feb 27 doi: 10.1016/j.jemermed.2018.12.047. PMID: 30826085

Immune complex disease.

Carter PM
Ann Rheum Dis 1973 May;32(3):265-71. doi: 10.1136/ard.32.3.265. PMID: 4146024 Free PMC Article

Hypersensitivity.

Turk JL
Scott Med J 1971 Jun;16(6):273-9. doi: 10.1177/003693307101600601. PMID: 4103763

See all (105)

Prognosis

Sex differences in injection site reactions with human vaccines.

Cook IF
Hum Vaccin 2009 Jul;5(7):441-9. Epub 2009 Jul 18 doi: 10.4161/hv.8476. PMID: 19377279

Vaccine allergy and pseudo-allergy.

Ponvert C, Scheinmann P
Eur J Dermatol 2003 Jan-Feb;13(1):10-5. PMID: 12609774

Prostaglandins. Their potential in clinical medicine.

Zurier RB
Postgrad Med 1980 Sep;68(3):70-81. doi: 10.1080/00325481.1980.11715530. PMID: 7433293

Immunologic evaluation of patients with cancer by delayed hypersensitivity reactions.

Burdick JF, Wells SA Jr, Herberman RB
Surg Gynecol Obstet 1975 Nov;141(5):779-94. PMID: 128144

Immunity in cutaneous leishmaniasis of the guinea-pig.

Bryceson AD, Bray RS, Wolstencroft RA, Dumonde DC
Clin Exp Immunol 1970 Sep;7(3):301-41. PMID: 4249071 Free PMC Article

See all (14)

Clinical prediction guides

Clinical observation and analysis of skin reactions caused by COVID-19 vaccination.

Li Y, Fan L, Mao Q, Luan X, Wang Z, Zeng N, Cheng Y, Li Y, Xia Q, Lu Z, Lu Q, Min W, Luo D
Dermatol Ther 2022 Oct;35(10):e15746. Epub 2022 Aug 10 doi: 10.1111/dth.15746. PMID: 36190010

Preclinical Efficacy and Anti-Inflammatory Mechanisms of Action of the Bruton Tyrosine Kinase Inhibitor Rilzabrutinib for Immune-Mediated Disease.

The vaccines-associated Arthus reaction.

Peng B, Wei M, Zhu FC, Li JX
Hum Vaccin Immunother 2019;15(11):2769-2777. Epub 2019 May 3 doi: 10.1080/21645515.2019.1602435. PMID: 30945978 Free PMC Article

Sex differences in injection site reactions with human vaccines.

Cook IF
Hum Vaccin 2009 Jul;5(7):441-9. Epub 2009 Jul 18 doi: 10.4161/hv.8476. PMID: 19377279

Pathology of inflammatory demyelinating neuropathies.

Prineas JW
Baillieres Clin Neurol 1994 Apr;3(1):1-24. PMID: 7921584

See all (39)

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Arthus reaction

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Supplemental Content

Table of contents

Clinical resources

Practice guidelines

Consumer resources

Reviews

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