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Anthracosilicosis

MedGen UID:
1958
•Concept ID:
C0003164
•
Disease or Syndrome
Synonym: Anthracosilicoses
SNOMED CT: Anthracosilicosis (33548005)
 
Monarch Initiative: MONDO:0006653

Definition

Fibrosis of the lung parenchyma caused by inhalation of carbon and silica dust. It manifests as shortness of breath. [from NCI]

Professional guidelines

PubMed

Anthracosilicosis and its symptomatic treatment.
GORDON B, MOTLEY HL
W V Med J 1949 Jun;45(6):125-32. PMID: 18127980

Recent clinical studies

Etiology

Associations of polymorphisms in the cytokine genes IL1β (rs16944), IL6 (rs1800795), IL12b (rs3212227) and growth factor VEGFA (rs2010963) with anthracosilicosis in coal miners in Russia and related genotoxic effects.
Volobaev VP, Larionov AV, Kalyuzhnaya EE, Serdyukova ES, Yakovleva S, Druzhinin VG, Babich OO, Hill EG, Semenihin VA, Panev NI, Minina VI, Sivanesan SD, Naoghare P, da Silva J, Barcelos GRM, Prosekov AY
Mutagenesis 2018 Apr 13;33(2):129-135. doi: 10.1093/mutage/gex047. PMID: 29378067
Diagnostic features of atherosclerosis development in miners having anthracosilicosis.
Panev NI, Zakharenkov VV, Korotenko OY, Filimonov SN, Panev RN, Gafarov NI, Luzina FA
Med Tr Prom Ekol 2016 Aug;(5):16-20. PMID: 30351698
Occupational health and safety regulation in the coal mining industry: public health at the workplace.
Weeks JL
Annu Rev Public Health 1991;12:195-207. doi: 10.1146/annurev.pu.12.050191.001211. PMID: 1828671
Dust exposure and mortality in an American chrysotile asbestos friction products plant.
McDonald AD, Fry JS, Woolley AJ, McDonald JC
Br J Ind Med 1984 May;41(2):151-7. doi: 10.1136/oem.41.2.151. PMID: 6326794Free PMC Article
Anthracosilicosis and bronchogenic carcinoma.
Myers CE
Dis Chest 1967 Dec;52(6):800-5. doi: 10.1378/chest.52.6.800. PMID: 6064983

Diagnosis

Silicosis as an unusual cause of symptomatic cervical adenopathy.
Baerts B, De Belie B, De Vos W, Van de Casteele E
J Stomatol Oral Maxillofac Surg 2023 Dec;124(6S):101493. Epub 2023 May 11 doi: 10.1016/j.jormas.2023.101493. PMID: 37172780
Diagnostic features of atherosclerosis development in miners having anthracosilicosis.
Panev NI, Zakharenkov VV, Korotenko OY, Filimonov SN, Panev RN, Gafarov NI, Luzina FA
Med Tr Prom Ekol 2016 Aug;(5):16-20. PMID: 30351698
The implication of background anthracosis in the development and progression of pulmonary adenocarcinoma.
Wang D, Minami Y, Shu Y, Konno S, Iijima T, Morishita Y, Noguchi M
Cancer Sci 2003 Aug;94(8):707-11. doi: 10.1111/j.1349-7006.2003.tb01506.x. PMID: 12901796Free PMC Article
Carcinoma of the lung and anthracosilicosis.
Scarano D, Fadali AM, Lemole GM
Chest 1972 Sep;62(3):251-4. doi: 10.1378/chest.62.3.251. PMID: 4341426
CARCINOMA AND ANTHRACOSILICOSIS.
NEALON TF Jr
Arch Environ Health 1964 Jun;8:882-5. doi: 10.1080/00039896.1964.10663770. PMID: 14157585

Therapy

Associations of polymorphisms in the cytokine genes IL1β (rs16944), IL6 (rs1800795), IL12b (rs3212227) and growth factor VEGFA (rs2010963) with anthracosilicosis in coal miners in Russia and related genotoxic effects.
Volobaev VP, Larionov AV, Kalyuzhnaya EE, Serdyukova ES, Yakovleva S, Druzhinin VG, Babich OO, Hill EG, Semenihin VA, Panev NI, Minina VI, Sivanesan SD, Naoghare P, da Silva J, Barcelos GRM, Prosekov AY
Mutagenesis 2018 Apr 13;33(2):129-135. doi: 10.1093/mutage/gex047. PMID: 29378067
Debilitating lung disease among surface coal miners with no underground mining tenure.
Halldin CN, Reed WR, Joy GJ, Colinet JF, Rider JP, Petsonk EL, Abraham JL, Wolfe AL, Storey E, Laney AS
J Occup Environ Med 2015 Jan;57(1):62-7. doi: 10.1097/JOM.0000000000000302. PMID: 25563541Free PMC Article
The "dirty chest"--correlations between chest radiography, multislice CT and tobacco burden.
Kirchner J, Goltz JP, Lorenz F, Obermann A, Kirchner EM, Kickuth R
Br J Radiol 2012 Apr;85(1012):339-45. Epub 2011 Sep 21 doi: 10.1259/bjr/62694750. PMID: 21937617Free PMC Article
Dust exposure and mortality in an American chrysotile asbestos friction products plant.
McDonald AD, Fry JS, Woolley AJ, McDonald JC
Br J Ind Med 1984 May;41(2):151-7. doi: 10.1136/oem.41.2.151. PMID: 6326794Free PMC Article
The anthracotic pneumoconioses.
Naeye RL
Curr Top Pathol 1971;55:37-68. doi: 10.1007/978-3-642-65208-0_2. PMID: 4333700

Prognosis

EUS-FNA and FDG-PET are complementary procedures in the diagnosis of enlarged mediastinal lymph nodes.
Bataille L, Lonneux M, Weynand B, Schoonbroodt D, Collard P, Deprez PH
Acta Gastroenterol Belg 2008 Apr-Jun;71(2):219-29. PMID: 18720933
The implication of background anthracosis in the development and progression of pulmonary adenocarcinoma.
Wang D, Minami Y, Shu Y, Konno S, Iijima T, Morishita Y, Noguchi M
Cancer Sci 2003 Aug;94(8):707-11. doi: 10.1111/j.1349-7006.2003.tb01506.x. PMID: 12901796Free PMC Article
Endoscopic ultrasonography of the mediastinum in the diagnosis of bronchial carcinoma.
Schüder G, Isringhaus H, Kubale B, Seitz G, Sybrecht GW
Thorac Cardiovasc Surg 1991 Oct;39(5):299-303. doi: 10.1055/s-2007-1019991. PMID: 1664546
Occupational safety and health implications of increased coal utilization.
Bridbord K, Costello J, Gamble J, Groce D, Hutchison M, Jones W, Merchant J, Ortmeyer C, Reger R, Wagner WL
Environ Health Perspect 1979 Dec;33:285-302. doi: 10.1289/ehp.7933285. PMID: 540621Free PMC Article
Nashville air pollution and health study.
Kenline PA, Conlee CJ
Public Health Rep (1896) 1967 Jan;82(1):17-29. PMID: 4959489Free PMC Article

Clinical prediction guides

Calcareous concretions and psammoma bodies in sputum smears: do these similar structures have different clinical significance?
Martínez-Girón R, Martínez-Torre S, Tamargo-Peláez ML, López-Cabanilles MD, Torre-Bayón C
Diagn Cytopathol 2014 Sep;42(9):759-65. Epub 2014 Feb 18 doi: 10.1002/dc.23120. PMID: 24550186
The "dirty chest"--correlations between chest radiography, multislice CT and tobacco burden.
Kirchner J, Goltz JP, Lorenz F, Obermann A, Kirchner EM, Kickuth R
Br J Radiol 2012 Apr;85(1012):339-45. Epub 2011 Sep 21 doi: 10.1259/bjr/62694750. PMID: 21937617Free PMC Article
EUS-FNA and FDG-PET are complementary procedures in the diagnosis of enlarged mediastinal lymph nodes.
Bataille L, Lonneux M, Weynand B, Schoonbroodt D, Collard P, Deprez PH
Acta Gastroenterol Belg 2008 Apr-Jun;71(2):219-29. PMID: 18720933
Anthracofibrosis attributed to mixed mineral dust exposure: report of three cases.
Naccache JM, Monnet I, Nunes H, Billon-Galland MA, Pairon JC, Guillon F, Valeyre D
Thorax 2008 Jul;63(7):655-7. doi: 10.1136/thx.2006.070243. PMID: 18587036
Dust exposure and mortality in an American chrysotile asbestos friction products plant.
McDonald AD, Fry JS, Woolley AJ, McDonald JC
Br J Ind Med 1984 May;41(2):151-7. doi: 10.1136/oem.41.2.151. PMID: 6326794Free PMC Article

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