U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Amnionitis

MedGen UID:
1490
•Concept ID:
C0002631
•
Disease or Syndrome
Synonym: Amnionitides
SNOMED CT: Amniotic cavity infection (10573002); Infection of amniotic cavity (10573002); Amnionitis (10573002)
 
Monarch Initiative: MONDO:0020710

Definition

Inflammation of the amnion. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAmnionitis

Professional guidelines

PubMed

The antibiotic treatment of PPROM study: systemic maternal and fetal markers and perinatal outcomes.
Mercer BM, Crouse DT, Goldenberg RL, Miodovnik M, Mapp DC, Meis PJ, Dombrowski MP; Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network
Am J Obstet Gynecol 2012 Feb;206(2):145.e1-9. Epub 2011 Sep 8 doi: 10.1016/j.ajog.2011.08.028. PMID: 22000668Free PMC Article
Prenatal diagnosis of thalassemia and hemoglobinopathies in Thailand: experience from 100 pregnancies.
Fucharoen S, Winichagoon P, Thonglairoam V, Siriboon W, Siritanaratkul N, Kanokpongsakdi S, Vantanasiri C
Southeast Asian J Trop Med Public Health 1991 Mar;22(1):16-29. PMID: 1948258
Prenatal diagnosis of beta-thalassaemia and sickle-cell anaemia. Experience with 24 cases.
Kan YW, Trecartin RF, Golbus MS, Filly RA
Lancet 1977 Feb 5;1(8006):269-71. doi: 10.1016/s0140-6736(77)91821-9. PMID: 64802

Recent clinical studies

Therapy

Maternal Origins of Neonatal Infections: What Do Obstetrician-Gynecologist Should/Could Do?
Germano C, Messina A, Massaro A, Attini R, Leo L, Manzoni P, Masturzo B
Am J Perinatol 2022 Dec;39(S 01):S31-S41. Epub 2022 Dec 19 doi: 10.1055/s-0042-1758858. PMID: 36535368
Refractory uterine atony: still a problem after all these years.
Balki M, Wong CA
Int J Obstet Anesth 2021 Nov;48:103207. Epub 2021 Jul 21 doi: 10.1016/j.ijoa.2021.103207. PMID: 34391025
Antenatal steroids and neonatal outcome after chorioamnionitis: a meta-analysis.
Been JV, Degraeuwe PL, Kramer BW, Zimmermann LJ
BJOG 2011 Jan;118(2):113-22. Epub 2010 Nov 4 doi: 10.1111/j.1471-0528.2010.02751.x. PMID: 21054759
Clinical role of amnio-infusion.
Ouzounian JG, Paul RH
Baillieres Clin Obstet Gynaecol 1996 Jun;10(2):259-72. doi: 10.1016/s0950-3552(96)80037-x. PMID: 8836484
Neonatal sepsis.
Driggers DA, Deiss F, Swedberg J, Johnson RB, Steiner JF
Am Fam Physician 1985 Aug;32(2):129-34. PMID: 3895874

Prognosis

Refractory uterine atony: still a problem after all these years.
Balki M, Wong CA
Int J Obstet Anesth 2021 Nov;48:103207. Epub 2021 Jul 21 doi: 10.1016/j.ijoa.2021.103207. PMID: 34391025
Timing of Histologic Progression from Chorio-Deciduitis to Chorio-Deciduo-Amnionitis in the Setting of Preterm Labor and Preterm Premature Rupture of Membranes with Sterile Amniotic Fluid.
Park CW, Park JS, Norwitz ER, Moon KC, Jun JK, Yoon BH
PLoS One 2015;10(11):e0143023. Epub 2015 Nov 17 doi: 10.1371/journal.pone.0143023. PMID: 26574743Free PMC Article
The role of anaerobic bacteria in bacteremia.
Brook I
Anaerobe 2010 Jun;16(3):183-9. Epub 2009 Dec 16 doi: 10.1016/j.anaerobe.2009.12.001. PMID: 20025984
Mode of delivery in the early preterm infant (<28 weeks).
Drife J
BJOG 2006 Dec;113 Suppl 3:81-5. doi: 10.1111/j.1471-0528.2006.01129.x. PMID: 17206971
Streptococcus pneumoniae infections in the neonate.
Hoffman JA, Mason EO, Schutze GE, Tan TQ, Barson WJ, Givner LB, Wald ER, Bradley JS, Yogev R, Kaplan SL
Pediatrics 2003 Nov;112(5):1095-102. doi: 10.1542/peds.112.5.1095. PMID: 14595052

Clinical prediction guides

Refractory uterine atony: still a problem after all these years.
Balki M, Wong CA
Int J Obstet Anesth 2021 Nov;48:103207. Epub 2021 Jul 21 doi: 10.1016/j.ijoa.2021.103207. PMID: 34391025
Pregnancy-related pharmacokinetics and antimicrobial prophylaxis during fetal surgery, cefazolin and clindamycin as examples.
Allegaert K, Muller AE, Russo F, Schoenmakers S, Deprest J, Koch BCP
Prenat Diagn 2020 Aug;40(9):1178-1184. Epub 2020 Jun 14 doi: 10.1002/pd.5753. PMID: 32441341
An elevated maternal serum C-reactive protein in the context of intra-amniotic inflammation is an indicator that the development of amnionitis, an intense fetal and AF inflammatory response are likely in patients with preterm labor: clinical implications.
Park CW, Yoon BH, Park JS, Jun JK
J Matern Fetal Neonatal Med 2013 Jun;26(9):847-53. doi: 10.3109/14767058.2013.783806. PMID: 23484918
Antenatal steroids and neonatal outcome after chorioamnionitis: a meta-analysis.
Been JV, Degraeuwe PL, Kramer BW, Zimmermann LJ
BJOG 2011 Jan;118(2):113-22. Epub 2010 Nov 4 doi: 10.1111/j.1471-0528.2010.02751.x. PMID: 21054759
Streptococcus pneumoniae infections in the neonate.
Hoffman JA, Mason EO, Schutze GE, Tan TQ, Barson WJ, Givner LB, Wald ER, Bradley JS, Yogev R, Kaplan SL
Pediatrics 2003 Nov;112(5):1095-102. doi: 10.1542/peds.112.5.1095. PMID: 14595052

Recent systematic reviews

Prevalence of Urinary Tract Infection and Its Associated Factors among Pregnant Women in Ethiopia: A Systematic Review and Meta-Analysis.
Getaneh T, Negesse A, Dessie G, Desta M, Tigabu A
Biomed Res Int 2021;2021:6551526. Epub 2021 Dec 1 doi: 10.1155/2021/6551526. PMID: 34901276Free PMC Article
Antenatal steroids and neonatal outcome after chorioamnionitis: a meta-analysis.
Been JV, Degraeuwe PL, Kramer BW, Zimmermann LJ
BJOG 2011 Jan;118(2):113-22. Epub 2010 Nov 4 doi: 10.1111/j.1471-0528.2010.02751.x. PMID: 21054759
Amnioinfusion for preterm rupture of membranes.
Hofmeyr GJ
Cochrane Database Syst Rev 2000;(2):CD000942. doi: 10.1002/14651858.CD000942. PMID: 10796224
Amnioinfusion for umbilical cord compression in labour.
Hofmeyr GJ
Cochrane Database Syst Rev 2000;(2):CD000013. doi: 10.1002/14651858.CD000013. PMID: 10796084

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...