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Vulvar intraepithelial neoplasia
Vulvar intraepithelial neoplasia (VIN) is widely accepted as the precursor lesion of vulvar squamous cell carcinoma (VSCC). VSCC arises via either a human papilloma virus (HPV)-associated pathway, or more commonly, via a mechanism independent of HPV, often being linked to chronic inflammatory conditions such as lichen sclerosus (LS). Accordingly, two distinct subtypes of VIN are recognized [from HPO]
Low grade vulvar intraepithelial neoplasia
An intraepithelial lesion of the vulvar squamous epithelium associated with HPV infection. It is characterized by mild cytologic atypia. [from NCI]
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