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The following term was not found in MedGen: Siphonoglossa.

Porcelain gallbladder

MedGen UID:: 1052569
•Concept ID:: CN377283
•: Finding

Synonyms:	Calcified gallbladder; Calcifying cholecystitis; Cholecystopathia chronica calcarea

HPO:	HP:6000451

Definition

Porcelain gallbladder refers to the condition in which the inner gallbladder wall is encrusted with calcium. The wall becomes brittle, hard, and often takes on a bluish hue. It is usually found incidentally on plain abdominal x-rays or other imaging because most patients are asymptomatic. [from HPO]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVPorcelain gallbladder

Abnormality of the digestive system
- Abnormality of the abdominal organs
  - Abnormality of the liver
    - Abnormality of the biliary system
      - Abnormality of the gallbladder
        Abnormal gallbladder morphology
        Porcelain gallbladder

Professional guidelines

PubMed

Interventional radiology's role in the diagnosis and management of patients with gallbladder carcinoma.

Fine GC, Smith TA, Stein SI, Madoff DC
Chin Clin Oncol 2019 Aug;8(4):40. Epub 2019 Aug 5 doi: 10.21037/cco.2019.07.09. PMID: 31431037

Metformin treatment prevents gallstone formation but mimics porcelain gallbladder in C57Bl/6 mice.

Dorvash MR, Khoshnood MJ, Saber H, Dehghanian A, Mosaddeghi P, Firouzabadi N
Eur J Pharmacol 2018 Aug 15;833:165-172. Epub 2018 Jun 5 doi: 10.1016/j.ejphar.2018.06.002. PMID: 29883669

Risk factors for biliary tract and ampullary carcinomas and prophylactic surgery for these factors.

Miyazaki M, Takada T, Miyakawa S, Tsukada K, Nagino M, Kondo S, Furuse J, Saito H, Tsuyuguchi T, Chijiiwa K, Kimura F, Yoshitomi H, Nozawa S, Yoshida M, Wada K, Amano H, Miura F; Japanese Association of Biliary Surgery; Japanese Society of Hepato-Pancreatic Surgery; Japan Society of Clinical Oncology
J Hepatobiliary Pancreat Surg 2008;15(1):15-24. Epub 2008 Feb 16 doi: 10.1007/s00534-007-1276-8. PMID: 18274840 Free PMC Article

See all (5)

Recent clinical studies

Etiology

Imaging Features of Premalignant Biliary Lesions and Predisposing Conditions with Pathologic Correlation.

Zulfiqar M, Chatterjee D, Yoneda N, Hoegger MJ, Ronot M, Hecht EM, Bastati N, Ba-Ssalamah A, Bashir MR, Fowler K
Radiographics 2022 Sep-Oct;42(5):1320-1337. Epub 2022 Aug 5 doi: 10.1148/rg.210194. PMID: 35930475

Rates of hypercalcemia and hyperparathyroidism among patients with porcelain gallbladder.

Berger M, Dy B, McKenzie T, Thompson G, Wermers R, Lyden M
Am J Surg 2020 Jul;220(1):127-131. Epub 2019 Oct 7 doi: 10.1016/j.amjsurg.2019.10.010. PMID: 31648774

Porcelain gallbladder.

Ansari S
Indian J Gastroenterol 2014 Jul;33(4):399. doi: 10.1007/s12664-013-0362-x. PMID: 23982704

Carcinoma gallbladder.

Biswas PK
Mymensingh Med J 2010 Jul;19(3):477-81. PMID: 20639849

Asymptomatic gallstones.

Gibney EJ
Br J Surg 1990 Apr;77(4):368-72. doi: 10.1002/bjs.1800770405. PMID: 2187558

See all (39)

Diagnosis

Gallbladder Disorders: A Comprehensive Review.

Lam R, Zakko A, Petrov JC, Kumar P, Duffy AJ, Muniraj T
Dis Mon 2021 Jul;67(7):101130. Epub 2021 Jan 18 doi: 10.1016/j.disamonth.2021.101130. PMID: 33478678

Porcelain Gallbladder.

Matsuura H, Matsushita H, Imamura R
Clin Gastroenterol Hepatol 2021 Dec;19(12):A30. Epub 2020 Aug 20 doi: 10.1016/j.cgh.2020.08.036. PMID: 32827726

Porcelain gallbladder.

Patel NJ, Caserta MP, DiSantis DJ
Abdom Radiol (NY) 2017 Jan;42(1):322-323. doi: 10.1007/s00261-016-0844-2. PMID: 27444785

The gallbladder: uncommon gallbladder conditions and unusual presentations of the common gallbladder pathological processes.

Revzin MV, Scoutt L, Smitaman E, Israel GM
Abdom Imaging 2015 Feb;40(2):385-99. doi: 10.1007/s00261-014-0203-0. PMID: 25063238

Carcinoma gallbladder.

Biswas PK
Mymensingh Med J 2010 Jul;19(3):477-81. PMID: 20639849

See all (61)

Therapy

Metformin treatment prevents gallstone formation but mimics porcelain gallbladder in C57Bl/6 mice.

Dorvash MR, Khoshnood MJ, Saber H, Dehghanian A, Mosaddeghi P, Firouzabadi N
Eur J Pharmacol 2018 Aug 15;833:165-172. Epub 2018 Jun 5 doi: 10.1016/j.ejphar.2018.06.002. PMID: 29883669

Intraumbilical versus periumbilical incision in laparoscopic cholecystectomy: A randomized controlled trial.

Lee JS, Hong TH
Int J Surg 2016 Sep;33 Pt A:83-7. Epub 2016 Aug 2 doi: 10.1016/j.ijsu.2016.07.071. PMID: 27494996

Gallbladder cancers: associated conditions, histological types, prognosis, and prevention.

Cariati A, Piromalli E, Cetta F
Eur J Gastroenterol Hepatol 2014 May;26(5):562-9. doi: 10.1097/MEG.0000000000000074. PMID: 24614695

Are new treatment methods of gallbladder stones the death-knell for gallstone surgery?

Parish KL, Chapman WC, Williams LF Jr, Richards WO
Am Surg 1991 Oct;57(10):634-41. PMID: 1833999

Asymptomatic gallstones.

Gibney EJ
Br J Surg 1990 Apr;77(4):368-72. doi: 10.1002/bjs.1800770405. PMID: 2187558

See all (6)

Prognosis

Imaging Features of Premalignant Biliary Lesions and Predisposing Conditions with Pathologic Correlation.

Dysplasia in Gallbladder: What Should We Do?

Rais R, González I, Chatterjee D
J Gastrointest Surg 2019 Apr;23(4):686-689. Epub 2018 Sep 13 doi: 10.1007/s11605-018-3955-y. PMID: 30215198

Gallbladder cancers: associated conditions, histological types, prognosis, and prevention.

Cariati A, Piromalli E, Cetta F
Eur J Gastroenterol Hepatol 2014 May;26(5):562-9. doi: 10.1097/MEG.0000000000000074. PMID: 24614695

Porcelain gallbladder: a benign process or concern for malignancy?

Schnelldorfer T
J Gastrointest Surg 2013 Jun;17(6):1161-8. Epub 2013 Feb 20 doi: 10.1007/s11605-013-2170-0. PMID: 23423431

Carcinoma gallbladder.

Biswas PK
Mymensingh Med J 2010 Jul;19(3):477-81. PMID: 20639849

See all (17)

Clinical prediction guides

Porcelain Gallbladder: Is Observation a Safe Option in Select Populations?

DesJardins H, Duy L, Scheirey C, Schnelldorfer T
J Am Coll Surg 2018 Jun;226(6):1064-1069. Epub 2018 Mar 2 doi: 10.1016/j.jamcollsurg.2017.11.026. PMID: 29505824

Porcelain Gallbladder: No Longer an Indication for Prophylactic Cholecystectomy.

Chen GL, Akmal Y, DiFronzo AL, Vuong B, O'Connor V
Am Surg 2015 Oct;81(10):936-40. PMID: 26463284

Seek and ye shall find: the importance of careful macroscopic examination and thorough sampling in 2522 cholecystectomy specimens.

Hayes BD, Muldoon C
Ann Diagn Pathol 2014 Jun;18(3):181-6. Epub 2014 Mar 31 doi: 10.1016/j.anndiagpath.2014.03.004. PMID: 24768494

The role of diffusion-weighted examination in non-polyploid gallbladder malignancies: A preliminary study.

Solak A, Solak I, Genç B, Sahin N
Turk J Gastroenterol 2013;24(2):148-53. doi: 10.4318/tjg.2013.0659. PMID: 23934462

Are new treatment methods of gallbladder stones the death-knell for gallstone surgery?

Parish KL, Chapman WC, Williams LF Jr, Richards WO
Am Surg 1991 Oct;57(10):634-41. PMID: 1833999

See all (8)