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EIF4A2 Gene Rearrangement

MedGen UID:
1809117
•Concept ID:
C5670802
•
Cell or Molecular Dysfunction
Synonyms: DDX2B Gene Rearrangement; eIF-4A-II Gene Rearrangement; eIF4A-II Gene Rearrangement; EIF4A2 Rearrangement; EIF4F Gene Rearrangement; Eukaryotic Translation Initiation Factor 4A2 Gene Rearrangement

Definition

A molecular abnormality indicating rearrangement of the EIF4A2 gene. [from NCI]

Recent clinical studies

Etiology

BCL6 gene translocation in follicular lymphoma: a harbinger of eventual transformation to diffuse aggressive lymphoma.
Akasaka T, Lossos IS, Levy R
Blood 2003 Aug 15;102(4):1443-8. Epub 2003 May 8 doi: 10.1182/blood-2002-08-2482. PMID: 12738680

Diagnosis

BCL6 gene translocation in follicular lymphoma: a harbinger of eventual transformation to diffuse aggressive lymphoma.
Akasaka T, Lossos IS, Levy R
Blood 2003 Aug 15;102(4):1443-8. Epub 2003 May 8 doi: 10.1182/blood-2002-08-2482. PMID: 12738680

Prognosis

BCL6 gene translocation in follicular lymphoma: a harbinger of eventual transformation to diffuse aggressive lymphoma.
Akasaka T, Lossos IS, Levy R
Blood 2003 Aug 15;102(4):1443-8. Epub 2003 May 8 doi: 10.1182/blood-2002-08-2482. PMID: 12738680

Clinical prediction guides

BCL6 gene translocation in follicular lymphoma: a harbinger of eventual transformation to diffuse aggressive lymphoma.
Akasaka T, Lossos IS, Levy R
Blood 2003 Aug 15;102(4):1443-8. Epub 2003 May 8 doi: 10.1182/blood-2002-08-2482. PMID: 12738680

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