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Anti-La/SS-B antibody positivity

MedGen UID:
1780945
•Concept ID:
C5539421
•
Laboratory or Test Result
HPO: HP:0032235

Definition

The presence of autoantibodies in the blood circulation that react against La/SSB autoantigens. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAnti-La/SS-B antibody positivity

Professional guidelines

PubMed

Association of Smoking and Obesity on the Risk of Developing Primary Sjögren Syndrome: A Population-based Cohort Study.
Servioli L, Maciel G, Nannini C, Crowson CS, Matteson EL, Cornec D, Berti A
J Rheumatol 2019 Jul;46(7):727-730. Epub 2019 Jan 15 doi: 10.3899/jrheum.180481. PMID: 30647188Free PMC Article
American College of Rheumatology classification criteria for Sjögren's syndrome: a data-driven, expert consensus approach in the Sjögren's International Collaborative Clinical Alliance cohort.
Shiboski SC, Shiboski CH, Criswell L, Baer A, Challacombe S, Lanfranchi H, Schiødt M, Umehara H, Vivino F, Zhao Y, Dong Y, Greenspan D, Heidenreich AM, Helin P, Kirkham B, Kitagawa K, Larkin G, Li M, Lietman T, Lindegaard J, McNamara N, Sack K, Shirlaw P, Sugai S, Vollenweider C, Whitcher J, Wu A, Zhang S, Zhang W, Greenspan J, Daniels T; Sjögren's International Collaborative Clinical Alliance (SICCA) Research Groups
Arthritis Care Res (Hoboken) 2012 Apr;64(4):475-87. doi: 10.1002/acr.21591. PMID: 22563590Free PMC Article
Early diagnosis and treatment of atrioventricular block in the fetus exposed to maternal anti-SSA/Ro-SSB/La antibodies: a prospective, observational, fetal kinetocardiogram-based study.
Rein AJ, Mevorach D, Perles Z, Gavri S, Nadjari M, Nir A, Elchalal U
Circulation 2009 Apr 14;119(14):1867-72. Epub 2009 Mar 30 doi: 10.1161/CIRCULATIONAHA.108.773143. PMID: 19332471

Recent systematic reviews

Sjögren syndrome associated with obsessive-compulsive disorder.
Freire de Carvalho J, Machado Ribeiro F
Eur Rev Med Pharmacol Sci 2020 Nov;24(22):11801-11803. doi: 10.26355/eurrev_202011_23836. PMID: 33275251

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