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  • The following term was not found in MedGen: <@JYP24>.

Spontaneous Abortion

MedGen UID:
39
Concept ID:
C0000786
Finding; Pathologic Function
Synonyms: Abortion, Spontaneous; Abortions, Spontaneous; Spontaneous Abortions

Definition

Fetal loss at less than 20 weeks of gestation. [from NCI]

Professional guidelines

PubMed

Nyirjesy P, Brookhart C, Lazenby G, Schwebke J, Sobel JD
Clin Infect Dis 2022 Apr 13;74(Suppl_2):S162-S168. doi: 10.1093/cid/ciab1057. PMID: 35416967
Auriti C, De Rose DU, Santisi A, Martini L, Piersigilli F, Bersani I, Ronchetti MP, Caforio L
Biochim Biophys Acta Mol Basis Dis 2021 Oct 1;1867(10):166198. Epub 2021 Jun 10 doi: 10.1016/j.bbadis.2021.166198. PMID: 34118406Free PMC Article
Griebel CP, Halvorsen J, Golemon TB, Day AA
Am Fam Physician 2005 Oct 1;72(7):1243-50. PMID: 16225027

Recent clinical studies

Etiology

Wang YX, Mínguez-Alarcón L, Gaskins AJ, Missmer SA, Rich-Edwards JW, Manson JE, Pan A, Chavarro JE
BMJ 2021 Mar 24;372:n530. doi: 10.1136/bmj.n530. PMID: 33762255Free PMC Article
Grippo A, Zhang J, Chu L, Guo Y, Qiao L, Zhang J, Myneni AA, Mu L
Rev Environ Health 2018 Sep 25;33(3):247-264. doi: 10.1515/reveh-2017-0033. PMID: 29975668Free PMC Article
Griebel CP, Halvorsen J, Golemon TB, Day AA
Am Fam Physician 2005 Oct 1;72(7):1243-50. PMID: 16225027
Nybo Andersen AM, Wohlfahrt J, Christens P, Olsen J, Melbye M
BMJ 2000 Jun 24;320(7251):1708-12. doi: 10.1136/bmj.320.7251.1708. PMID: 10864550Free PMC Article
McBride WZ
Am Fam Physician 1991 Jan;43(1):175-82. PMID: 1986486

Diagnosis

Yao Y, Ye Y, Chen J, Zhang M, Cai X, Zheng C
Am J Reprod Immunol 2024 May;91(5):e13859. doi: 10.1111/aji.13859. PMID: 38722063
Manning S, Kuhn D
Emerg Med Clin North Am 2023 May;41(2):295-305. doi: 10.1016/j.emc.2022.12.003. PMID: 37024165
Levine D
Radiology 2007 Nov;245(2):385-97. doi: 10.1148/radiol.2452061031. PMID: 17940301
Griebel CP, Halvorsen J, Golemon TB, Day AA
Am Fam Physician 2005 Oct 1;72(7):1243-50. PMID: 16225027
McBride WZ
Am Fam Physician 1991 Jan;43(1):175-82. PMID: 1986486

Therapy

McLindon LA, James G, Beckmann MM, Bertolone J, Mahomed K, Vane M, Baker T, Gleed M, Grey S, Tettamanzi L, Mol BWJ, Li W
Hum Reprod 2023 Apr 3;38(4):560-568. doi: 10.1093/humrep/dead029. PMID: 36806843Free PMC Article
Jiang Y, Wang L, Shen H, Wang B, Wu J, Hu K, Wang Y, Ma B, Zhang X
Fertil Steril 2023 Apr;119(4):597-605. Epub 2022 Dec 24 doi: 10.1016/j.fertnstert.2022.12.035. PMID: 36574915
Devall AJ, Papadopoulou A, Podesek M, Haas DM, Price MJ, Coomarasamy A, Gallos ID
Cochrane Database Syst Rev 2021 Apr 19;4(4):CD013792. doi: 10.1002/14651858.CD013792.pub2. PMID: 33872382Free PMC Article
Showell MG, Mackenzie-Proctor R, Jordan V, Hart RJ
Cochrane Database Syst Rev 2020 Aug 27;8(8):CD007807. doi: 10.1002/14651858.CD007807.pub4. PMID: 32851663Free PMC Article
Rooney KL, Domar AD
Dialogues Clin Neurosci 2018 Mar;20(1):41-47. doi: 10.31887/DCNS.2018.20.1/klrooney. PMID: 29946210Free PMC Article

Prognosis

Lawrence ER, Klein TJ, Beyuo TK
Obstet Gynecol Clin North Am 2022 Dec;49(4):713-733. doi: 10.1016/j.ogc.2022.07.001. PMID: 36328676
Wang YX, Mínguez-Alarcón L, Gaskins AJ, Missmer SA, Rich-Edwards JW, Manson JE, Pan A, Chavarro JE
BMJ 2021 Mar 24;372:n530. doi: 10.1136/bmj.n530. PMID: 33762255Free PMC Article
Phillips J, Millum J
Bioethics 2015 Jul;29(6):413-23. Epub 2014 Nov 14 doi: 10.1111/bioe.12120. PMID: 25395144Free PMC Article
Holmes MM, Resnick HS, Kilpatrick DG, Best CL
Am J Obstet Gynecol 1996 Aug;175(2):320-4; discussion 324-5. doi: 10.1016/s0002-9378(96)70141-2. PMID: 8765248
BENSON RC
Calif Med 1950 Jun;72(6):442-6. PMID: 15414445Free PMC Article

Clinical prediction guides

He Y, Wang L, Tang R, Jin H, Liu B, Chen S, Mu H, Wang X
J Affect Disord 2024 Jun 1;354:258-266. Epub 2024 Mar 13 doi: 10.1016/j.jad.2024.03.026. PMID: 38484879
Li LJ, Du R, Loy SL, Chong YS, Chan JKY, Wong TY, Eriksson JG, Huang Z, Zhang C
Fertil Steril 2022 Oct;118(4):748-757. Epub 2022 Aug 16 doi: 10.1016/j.fertnstert.2022.06.033. PMID: 35981917
Kalantari N, Gorgani-Firouzjaee T, Moulana Z, Chehrazi M, Ghaffari S
Microb Pathog 2021 Sep;158:105070. Epub 2021 Jun 26 doi: 10.1016/j.micpath.2021.105070. PMID: 34186117
Practice Committees of the American Society for Reproductive Medicine and the Society for Reproductive Endocrinology and Infertility
Fertil Steril 2021 Jun;115(6):1416-1423. Epub 2021 Apr 4 doi: 10.1016/j.fertnstert.2021.02.010. PMID: 33827766
Houghton DE, Moll S
Vasc Med 2017 Dec;22(6):545-550. Epub 2017 Nov 5 doi: 10.1177/1358863X17737374. PMID: 29103369

Recent systematic reviews

Desaunay P, Eude LG, Dreyfus M, Alexandre C, Fedrizzi S, Alexandre J, Uguz F, Guénolé F
Paediatr Drugs 2023 May;25(3):247-265. Epub 2023 Feb 28 doi: 10.1007/s40272-023-00561-2. PMID: 36853497
Zhao QY, Li QH, Fu YY, Ren CE, Jiang AF, Meng YH
Front Immunol 2022;13:994888. Epub 2022 Dec 8 doi: 10.3389/fimmu.2022.994888. PMID: 36569856Free PMC Article
Fornaro M, Maritan E, Ferranti R, Zaninotto L, Miola A, Anastasia A, Murru A, Solé E, Stubbs B, Carvalho AF, Serretti A, Vieta E, Fusar-Poli P, McGuire P, Young AH, Dazzan P, Vigod SN, Correll CU, Solmi M
Am J Psychiatry 2020 Jan 1;177(1):76-92. Epub 2019 Oct 18 doi: 10.1176/appi.ajp.2019.19030228. PMID: 31623458
Maraka S, Ospina NM, O'Keeffe DT, Espinosa De Ycaza AE, Gionfriddo MR, Erwin PJ, Coddington CC 3rd, Stan MN, Murad MH, Montori VM
Thyroid 2016 Apr;26(4):580-90. Epub 2016 Mar 3 doi: 10.1089/thy.2015.0418. PMID: 26837268Free PMC Article
Pritts EA, Parker WH, Olive DL
Fertil Steril 2009 Apr;91(4):1215-23. Epub 2008 Mar 12 doi: 10.1016/j.fertnstert.2008.01.051. PMID: 18339376

Supplemental Content

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    Practice guidelines

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