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  • The following terms were not found in MedGen: ellipsis, qqtest20, negated, existssimilar.

Tessier number 1 facial cleft

MedGen UID:
1634662
Concept ID:
C4703417
Congenital Abnormality
HPO: HP:0031572

Definition

As seen in a typical cleft lip, a cleft of the lip is found in the region of the cupid's bow. The nostril is cleft through the alar dome and extends above onto the nasal dorsum. It passes medial to a normal, but dys- topic, medial canthus. There is an alveolar cleft between the central and lateral incisors that extends above through the pyriform margin lateral to the anterior nasal spine; the nasal septum is not involved. The bony cleft extends through the nasal bone or between the junction of the nasal bone and frontal process of the maxilla. Above the cleft lip, the clefting of the alar dome is associated with deviation to the opposite side of the shortened and broadened columella and nasal tip. Extension of the soft tissue cleft onto the nasal dorsum can be manifest as a series of vertical soft tissue furrows and ridges. Vertical inner canthal dysto- pia and severe telecanthus mark the superior aspect of the Number 1 facial cleft. A cranial soft tissue extension characterized by a tongue-like projection of the frontal hairline delineates the number 13 cleft. Skeletal clefting of the maxilla may extend posteriorly to form a complete cleft of the hard and soft palate. The maxilla is hypoplastic in all three dimensions. There is a keel-shaped alveolus and anterior open bite. Normal septation is preserved between the nasal cavity and the hypoplastic maxillary antrum on the affected side. Distortion of the nasal skeleton produces gross flattening of the nasal dorsum. There is asymmetry of the pterygoid plates, of the greater and lesser wings of the sphenoid, and of the floor of the anterior cranial fossa. The distortion of the cranial base may result in a mild plagiocephaly. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVTessier number 1 facial cleft

Recent clinical studies

Etiology

Yu BF, Wei SY, Dai CC, Wei J
J Craniofac Surg 2022 Jan-Feb 01;33(1):183-186. doi: 10.1097/SCS.0000000000008032. PMID: 34320576
Raposo-Amaral CE, Oliveira YM, Denadai R, Ghizoni E, Raposo-Amaral CA
J Craniofac Surg 2021 Oct 1;32(7):e638-e642. doi: 10.1097/SCS.0000000000007648. PMID: 33770026
Chapchay K, Zaga J, Billig A, Adler N, Margulis A
Ann Plast Surg 2019 Mar;82(3):289-291. doi: 10.1097/SAP.0000000000001688. PMID: 30562204
Racz C, Dakpé S, Kadlub N, Testelin S, Devauchelle B, Rachwalski M, Picard A
J Craniomaxillofac Surg 2018 Jan;46(1):22-27. Epub 2017 Oct 27 doi: 10.1016/j.jcms.2017.10.012. PMID: 29239768
da Silva Freitas R, Alonso N, Shin JH, Busato L, Ono MC, Cruz GA
J Craniofac Surg 2008 Sep;19(5):1348-52. doi: 10.1097/SCS.0b013e318184326e. PMID: 18812861

Diagnosis

James O, Sabo VY, Adamson OO, Otoghile B, Adekunle AA, Adeyemo WL, Ladeinde AL, Ogunlewe MO
Cleft Palate Craniofac J 2023 Feb;60(2):133-141. Epub 2021 Nov 17 doi: 10.1177/10556656211055012. PMID: 34787018
Bubanale SC, Kurbet SB, De Piedade Sequeira LMG
Indian J Ophthalmol 2017 Jul;65(7):610-612. doi: 10.4103/ijo.IJO_914_16. PMID: 28724820Free PMC Article
Morgan AL, Cason R, El Amm CA
J Craniofac Surg 2016 Nov;27(8):e785-e787. doi: 10.1097/SCS.0000000000003129. PMID: 28005824
Galante G, Dado DV
Plast Reconstr Surg 1991 Jul;88(1):131-5. PMID: 2052642
Delaire J, Tessier P, Tulasne JF, Resche F
Head Neck Surg 1980 Nov-Dec;3(2):105-22. doi: 10.1002/hed.2890030205. PMID: 7440178

Therapy

Stelnicki EJ, Hoffman W, Foster R, Lopoo J, Longaker M
J Craniofac Surg 1998 Nov;9(6):557-62; discussion 563. doi: 10.1097/00001665-199811000-00012. PMID: 10029770
Scheuerle AE, Good RA, Habal MB
J Craniofac Surg 1990 Apr;1(2):88-90. doi: 10.1097/00001665-199001020-00003. PMID: 2094477

Prognosis

Raposo-Amaral CE, Oliveira YM, Denadai R, Ghizoni E, Raposo-Amaral CA
J Craniofac Surg 2021 Oct 1;32(7):e638-e642. doi: 10.1097/SCS.0000000000007648. PMID: 33770026
Watanabe A, Yoshida S, Ishii T, Saito C, Shibahara T
Bull Tokyo Dent Coll 2019 Dec 10;60(4):291-296. Epub 2019 Nov 22 doi: 10.2209/tdcpublication.2018-0070. PMID: 31761879
Racz C, Dakpé S, Kadlub N, Testelin S, Devauchelle B, Rachwalski M, Picard A
J Craniomaxillofac Surg 2018 Jan;46(1):22-27. Epub 2017 Oct 27 doi: 10.1016/j.jcms.2017.10.012. PMID: 29239768
da Silva Freitas R, Alonso N, Busato L, Ueda WK, Hota T, Medeiros SH, Kunz RT
J Craniofac Surg 2010 Mar;21(2):390-5. doi: 10.1097/SCS.0b013e3181cfa6b1. PMID: 20186077
Galante G, Dado DV
Plast Reconstr Surg 1991 Jul;88(1):131-5. PMID: 2052642

Clinical prediction guides

Kalantar-Hormozi A, Noori M, Karimi A
J Craniofac Surg 2023 Nov-Dec 01;34(8):e790-e793. Epub 2023 Aug 25 doi: 10.1097/SCS.0000000000009679. PMID: 37622550
Yu BF, Wei SY, Dai CC, Wei J
J Craniofac Surg 2022 Jan-Feb 01;33(1):183-186. doi: 10.1097/SCS.0000000000008032. PMID: 34320576
Savastano CP, Bernardi P, Seuánez HN, Moreira MÂ, Orioli IM
Birth Defects Res A Clin Mol Teratol 2014 Apr;100(4):300-6. Epub 2014 Feb 12 doi: 10.1002/bdra.23216. PMID: 24677696
Fearon JA
J Craniofac Surg 2008 Jan;19(1):110-2. doi: 10.1097/SCS.0b013e31815ca1ba. PMID: 18216674
Cannistrà C, Bontemps C, Valero R, Iannetti G, Barbet JP
Plast Reconstr Surg 2006 Dec;118(7):1538-1542. doi: 10.1097/01.prs.0000240818.64018.2a. PMID: 17102725

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