Fetal aminopterin syndrome

MedGen UID:: 98491
•Concept ID:: C0432367
•: Disease or Syndrome

Synonyms:	Aminopterin embryopathy syndrome; Aminopterin fetopathy syndrome; Aminopterin syndrome; Aminopterin/methotrexate embryofetopathy; Fetal methotrexate syndrome
SNOMED CT:	Fetal aminopterin syndrome (65986000); Fetal aminopterin/methotrexate syndrome (65986000); Foetal aminopterin/methotrexate syndrome (65986000); Foetal aminopterin syndrome (65986000); Aminopterin embryopathy syndrome (65986000)
Modes of inheritance:	Not genetically inherited MedGen UID: 988794 •Concept ID: CN307044 • Finding Source: Orphanet clinical entity without genetic inheritance. See: This record Not genetically inherited (Orphanet)

Monarch Initiative:	MONDO:0016004
Orphanet:	ORPHA1908

Definition

A syndrome of developmental anomalies characterized by growth deficiency, facial dysmorphism and skull, limb and neural defects secondary to maternal exposure to aminopterin or methotrexate (MTX) during pregnancy. [from ORDO]

Term Hierarchy

GTR
MeSH
Orphanet

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVFetal aminopterin syndrome

Congenital, Hereditary, and Neonatal Diseases and Abnormalities
- Fetal disorder
  - Fetal aminopterin syndrome

Follow this link to review classifications for Fetal aminopterin syndrome in Orphanet.

Professional guidelines

PubMed

Prenatal diagnosis of the fragile X using thymidine induction.

Sutherland GR, Baker E, Purvis-Smith S, Hockey A, Krumins E, Eichenbaum SZ
Prenat Diagn 1987 Mar;7(3):197-202. doi: 10.1002/pd.1970070307. PMID: 2954037

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