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Pectobacterium carotovorum infection

MedGen UID:
965835
Concept ID:
CN281753
Disease or Syndrome
Synonyms: Pectobacterium caused disease or disorder; Pectobacterium disease or disorder; Pectobacterium infectious disease
 
Monarch Initiative: MONDO:0005122

Definition

A bacterial infection induced by Pectobacterium carotovorum which is is a bacterium of the family Enterobacteriaceae. This bacterius is a ubiquitous plant pathogen with a wide host range (carrot, potato, tomato, leafy greens, squash and other cucurbits, onion, green peppers, African violets etc.), able to cause disease in almost any plant tissue it invades. It is a very economically important pathogen in terms of postharvest losses, and a common cause of decay in stored fruits and vegetables. Decay caused by E. carotovora is often simply referred to as "bacterial soft rot" (BSR) though this may also be caused by other bacteria. Most plants or plant parts can resist invasion by the bacteria, unless some type of wound is present. High humidity and temperatures around 30°C favor development of decay. Mutants can be produced which are less virulent. Virulence factors include: pectinases, cellulases, (which degrade plant cell walls), and also proteases, lipases, xylanases and nucleases (along with the normal virulence factors for pathogens – Fe acquisition, LPS integrity, multiple global regulatory systems). [from MONDO]

Recent clinical studies

Etiology

Ahmed NU, Park JI, Seo MS, Kumar TS, Lee IH, Park BS, Nou IS
Mol Biol Rep 2012 Apr;39(4):3649-57. Epub 2011 Jul 1 doi: 10.1007/s11033-011-1139-x. PMID: 21720758
Razavi SM, Zarrini G, Rad FG
Bioorg Khim 2011 Mar-Apr;37(2):269-72. doi: 10.1134/s1068162011020130. PMID: 21717896
Fukuoka S, Howe J, Andrä J, Gutsmann T, Rössle M, Brandenburg K
Biochim Biophys Acta 2008 Oct;1778(10):2051-7. Epub 2008 Apr 6 doi: 10.1016/j.bbamem.2008.03.022. PMID: 18440300

Therapy

Razavi SM, Zarrini G, Rad FG
Bioorg Khim 2011 Mar-Apr;37(2):269-72. doi: 10.1134/s1068162011020130. PMID: 21717896
Choi J, Moon E
J Microbiol Biotechnol 2009 Aug;19(8):792-802. doi: 10.4014/jmb.0809.497. PMID: 19734717

Clinical prediction guides

Benguettat O, Jneid R, Soltys J, Loudhaief R, Brun-Barale A, Osman D, Gallet A
PLoS Pathog 2018 Sep;14(9):e1007279. Epub 2018 Sep 4 doi: 10.1371/journal.ppat.1007279. PMID: 30180210Free PMC Article

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