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Cervical disk degenerative disorder

MedGen UID:
96081
•Concept ID:
C0410606
•
Disease or Syndrome
Synonym: Cervical disc degenerative disorder
 
Monarch Initiative: MONDO:0044343

Definition

Any degenerative disorder affecting one or more vertebral discs of the cervical spine. [from NCI]

Professional guidelines

PubMed

Management of the Patient with Cervical Cord Compression but no Evidence of Myelopathy: What Should We do?
Naito K, Yamagata T, Ohata K, Takami T
Neurosurg Clin N Am 2018 Jan;29(1):145-152. Epub 2017 Oct 27 doi: 10.1016/j.nec.2017.09.010. PMID: 29173427
Cervical radiculopathy: epidemiology, etiology, diagnosis, and treatment.
Woods BI, Hilibrand AS
J Spinal Disord Tech 2015 Jun;28(5):E251-9. doi: 10.1097/BSD.0000000000000284. PMID: 25985461
Thoracic disk disease: diagnosis and treatment.
Vanichkachorn JS, Vaccaro AR
J Am Acad Orthop Surg 2000 May-Jun;8(3):159-69. doi: 10.5435/00124635-200005000-00003. PMID: 10874223

Recent clinical studies

Etiology

Is Cervical Disk Arthroplasty a Suitable Alternative to Treat Degenerative Cervical Myelopathy?
Schupper AJ, Boylan AJ, Houten JK
Clin Spine Surg 2023 Nov 1;36(9):356-362. Epub 2023 Sep 8 doi: 10.1097/BSD.0000000000001528. PMID: 37684716
Spinal Perineural Cysts among European Patients.
Kozłowski P, Kalinowski P, Kozłowska M, Jankiewicz M, Budny A, Starosławska E, Burdan F
J Neurol Surg A Cent Eur Neurosurg 2021 Sep;82(5):463-467. Epub 2021 Apr 1 doi: 10.1055/s-0040-1722194. PMID: 33822351
Management of the Patient with Cervical Cord Compression but no Evidence of Myelopathy: What Should We do?
Naito K, Yamagata T, Ohata K, Takami T
Neurosurg Clin N Am 2018 Jan;29(1):145-152. Epub 2017 Oct 27 doi: 10.1016/j.nec.2017.09.010. PMID: 29173427
Degenerative Cervical Myelopathy: A Spectrum of Related Disorders Affecting the Aging Spine.
Tetreault L, Goldstein CL, Arnold P, Harrop J, Hilibrand A, Nouri A, Fehlings MG
Neurosurgery 2015 Oct;77 Suppl 4:S51-67. doi: 10.1227/NEU.0000000000000951. PMID: 26378358
Cervical disk prolapse.
Houser OW, Onofrio BM, Miller GM, Folger WN, Smith PL
Mayo Clin Proc 1995 Oct;70(10):939-45. doi: 10.4065/70.10.939. PMID: 7564544

Diagnosis

Imaging of Degenerative and Infectious Conditions of the Spine.
Shah LM, Ross JS
Neurosurgery 2016 Sep;79(3):315-35. doi: 10.1227/NEU.0000000000001323. PMID: 27352276
Cervical radiculopathy: epidemiology, etiology, diagnosis, and treatment.
Woods BI, Hilibrand AS
J Spinal Disord Tech 2015 Jun;28(5):E251-9. doi: 10.1097/BSD.0000000000000284. PMID: 25985461
Total disk arthroplasty.
Lin EL, Wang JC
J Am Acad Orthop Surg 2006 Dec;14(13):705-14. doi: 10.5435/00124635-200612000-00002. PMID: 17148618
Thoracic disk disease: diagnosis and treatment.
Vanichkachorn JS, Vaccaro AR
J Am Acad Orthop Surg 2000 May-Jun;8(3):159-69. doi: 10.5435/00124635-200005000-00003. PMID: 10874223
Cervical disk prolapse.
Houser OW, Onofrio BM, Miller GM, Folger WN, Smith PL
Mayo Clin Proc 1995 Oct;70(10):939-45. doi: 10.4065/70.10.939. PMID: 7564544

Therapy

Mid-term and Long-term Outcomes After Total Cervical Disk Arthroplasty Compared With Anterior Cervical Discectomy and Fusion: A Systematic Review and Meta-analysis of Randomized Controlled Trials.
Kim LJY, Mazur MD, Dailey AT
Clin Spine Surg 2023 Nov 1;36(9):339-355. Epub 2023 Sep 22 doi: 10.1097/BSD.0000000000001537. PMID: 37735768
Is Cervical Disk Arthroplasty a Suitable Alternative to Treat Degenerative Cervical Myelopathy?
Schupper AJ, Boylan AJ, Houten JK
Clin Spine Surg 2023 Nov 1;36(9):356-362. Epub 2023 Sep 8 doi: 10.1097/BSD.0000000000001528. PMID: 37684716
Cost-effectiveness of anterior surgical decompression surgery for cervical degenerative disk disease: a systematic review of economic evaluations.
Schuermans VNE, Smeets AYJM, Boselie AFM, Zarrouk O, Hermans SMM, Droeghaag R, Curfs I, Evers SMAA, van Santbrink H
Eur Spine J 2022 May;31(5):1206-1218. Epub 2022 Feb 28 doi: 10.1007/s00586-022-07137-7. PMID: 35224672
Cervical Disk Arthroplasty.
Koreckij TD, Gandhi SD, Park DK
J Am Acad Orthop Surg 2019 Feb 1;27(3):e96-e104. doi: 10.5435/JAAOS-D-17-00231. PMID: 30285984
Cervical radiculopathy: epidemiology, etiology, diagnosis, and treatment.
Woods BI, Hilibrand AS
J Spinal Disord Tech 2015 Jun;28(5):E251-9. doi: 10.1097/BSD.0000000000000284. PMID: 25985461

Prognosis

The imaging of cervical spondylotic myeloradiculopathy.
Hesni S, Baxter D, Saifuddin A
Skeletal Radiol 2023 Dec;52(12):2341-2365. Epub 2023 Apr 18 doi: 10.1007/s00256-023-04329-0. PMID: 37071191
Management of the Patient with Cervical Cord Compression but no Evidence of Myelopathy: What Should We do?
Naito K, Yamagata T, Ohata K, Takami T
Neurosurg Clin N Am 2018 Jan;29(1):145-152. Epub 2017 Oct 27 doi: 10.1016/j.nec.2017.09.010. PMID: 29173427
Is Total Disk Replacement a Cost-effective Treatment for Cervical Degenerative Disk Disease?
Wiedenhöfer B, Nacke J, Stephan M, Richter W, Carstens C, Eichler M
Clin Spine Surg 2017 Jun;30(5):E530-E534. doi: 10.1097/BSD.0000000000000189. PMID: 28525473
Neck pain, cervical radiculopathy, and cervical myelopathy: pathophysiology, natural history, and clinical evaluation.
Rao R
Instr Course Lect 2003;52:479-88. PMID: 12690874
Thoracic disk disease: diagnosis and treatment.
Vanichkachorn JS, Vaccaro AR
J Am Acad Orthop Surg 2000 May-Jun;8(3):159-69. doi: 10.5435/00124635-200005000-00003. PMID: 10874223

Clinical prediction guides

Mid-term and Long-term Outcomes After Total Cervical Disk Arthroplasty Compared With Anterior Cervical Discectomy and Fusion: A Systematic Review and Meta-analysis of Randomized Controlled Trials.
Kim LJY, Mazur MD, Dailey AT
Clin Spine Surg 2023 Nov 1;36(9):339-355. Epub 2023 Sep 22 doi: 10.1097/BSD.0000000000001537. PMID: 37735768
Is Cervical Disk Arthroplasty a Suitable Alternative to Treat Degenerative Cervical Myelopathy?
Schupper AJ, Boylan AJ, Houten JK
Clin Spine Surg 2023 Nov 1;36(9):356-362. Epub 2023 Sep 8 doi: 10.1097/BSD.0000000000001528. PMID: 37684716
The imaging of cervical spondylotic myeloradiculopathy.
Hesni S, Baxter D, Saifuddin A
Skeletal Radiol 2023 Dec;52(12):2341-2365. Epub 2023 Apr 18 doi: 10.1007/s00256-023-04329-0. PMID: 37071191
Safety and Effectiveness of the Flexible Cervical Implant: Preliminary Short-Term Clinical Results.
Alvarez CE, Saal-Zapata G, Rodríguez-Varela R, Ginocchio F, Pacussich C
World Neurosurg 2022 Feb;158:e122-e127. Epub 2021 Oct 20 doi: 10.1016/j.wneu.2021.10.122. PMID: 34687929
Spinal Perineural Cysts among European Patients.
Kozłowski P, Kalinowski P, Kozłowska M, Jankiewicz M, Budny A, Starosławska E, Burdan F
J Neurol Surg A Cent Eur Neurosurg 2021 Sep;82(5):463-467. Epub 2021 Apr 1 doi: 10.1055/s-0040-1722194. PMID: 33822351

Recent systematic reviews

Long-Term Clinical and Radiographic Outcomes After Bryan Cervical Disk Arthroplasty: A Systematic Literature Review.
Perna A, Velluto C, Smakaj A, Caredda M, Proietti L, Santagada DA, Candura D, Meluzio MC, Tamburrelli FC, Genitiempo M
Acta Neurochir Suppl 2023;135:321-329. doi: 10.1007/978-3-031-36084-8_49. PMID: 38153488
Mid-term and Long-term Outcomes After Total Cervical Disk Arthroplasty Compared With Anterior Cervical Discectomy and Fusion: A Systematic Review and Meta-analysis of Randomized Controlled Trials.
Kim LJY, Mazur MD, Dailey AT
Clin Spine Surg 2023 Nov 1;36(9):339-355. Epub 2023 Sep 22 doi: 10.1097/BSD.0000000000001537. PMID: 37735768
Is Cervical Disk Arthroplasty a Suitable Alternative to Treat Degenerative Cervical Myelopathy?
Schupper AJ, Boylan AJ, Houten JK
Clin Spine Surg 2023 Nov 1;36(9):356-362. Epub 2023 Sep 8 doi: 10.1097/BSD.0000000000001528. PMID: 37684716
Cost-effectiveness of anterior surgical decompression surgery for cervical degenerative disk disease: a systematic review of economic evaluations.
Schuermans VNE, Smeets AYJM, Boselie AFM, Zarrouk O, Hermans SMM, Droeghaag R, Curfs I, Evers SMAA, van Santbrink H
Eur Spine J 2022 May;31(5):1206-1218. Epub 2022 Feb 28 doi: 10.1007/s00586-022-07137-7. PMID: 35224672
Cervical Disk Arthroplasty Versus Anterior Cervical Decompression and Fusion for the Treatment of 2-Level Cervical Spondylopathy: A Systematic Review and Meta-analysis.
Kuang L, Chen Y, Wang B, Li L, Lü G
Clin Spine Surg 2016 Nov;29(9):372-382. doi: 10.1097/BSD.0000000000000395. PMID: 27295435

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